Protein
50S ribosomal protein L1
Organism
Helicobacter pylori (strain ATCC 700392 / 26695)
Function
Peptides originating from the N-terminal end of L1 have antibacterial activity against bacteria such as E.coli and B.megaterium and modest antifungal activities. Has no effect on H.pylori itself. Peptides are not hemolytic against mammalian cells. These peptides may be released in the stomach during altruistic lysis to kill other fast growing bacteria.
Similarity
Belongs to the universal ribosomal protein uL1 family.
Sequence
MAKKVFKRLEKLFSKIQNDKAYGVEQGVEVVKSLASAKFDETVEVALRLGVDPRHADQMVRGAVVLPHGTGKKVRVAVFAKDIKQDEAKNAGADVVGGDDLAEEIKNGRIDFDMVIATPDMMAVVGKVGRILGPKGLMPNPKTGTVTMDIAKAVSNAKSGQVNFRVDKKGNVHAPIGKASFPEEKIKENMLELVKTINRLKPSSAKGKYIRNAALSLTMSPSVSLDAQELMDIK