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rpfD

Gene
rpfD
Protein
Resuscitation-promoting factor RpfD
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
154 amino acids
Function
Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity).
Similarity
Belongs to the transglycosylase family. Rpf subfamily.
Mass
15.679 kDa
Sequence
MTPGLLTTAGAGRPRDRCARIVCTVFIETAVVATMFVALLGLSTISSKADDIDWDAIAQCESGGNWAANTGNGLYGGLQISQATWDSNGGVGSPAAASPQQQIEVADNIMKTQGPGAWPKCSSCSQGDAPLGSLTHILTFLAAETGGCSGSRDD

Gene
rpfD
Protein
Resuscitation-promoting factor RpfD
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
154 amino acids
Function
Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.
Similarity
Belongs to the transglycosylase family. Rpf subfamily.
Mass
15.679 kDa
Sequence
MTPGLLTTAGAGRPRDRCARIVCTVFIETAVVATMFVALLGLSTISSKADDIDWDAIAQCESGGNWAANTGNGLYGGLQISQATWDSNGGVGSPAAASPQQQIEVADNIMKTQGPGAWPKCSSCSQGDAPLGSLTHILTFLAAETGGCSGSRDD