Protein
mRNA-capping enzyme subunit alpha
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity).
Similarity
Belongs to the eukaryotic GTase family.
Sequence
MEQPGPITDIAKPGIKAPRDLAISLREEVARILGRSSIGFPGAQPVSFARKHLEELRREDYYVCEKSDGIRYLLYLTVDEEGQEVQYLIDRKNDYWFLPRNSMHFPMPNDIQAFHRGTIIDGELVMDTVPGTNGRKEPRFLVFDLLALDDKAELLNKPLDKRLGYFSAYIYEPYKKLLQQFPQEIPFMAFKVEMKRMELSYGIETMFREVIPALKHDSDGLIFTCRTTPYHFGTDPHILKWKAPHENTLDFRMRLNFPLVQATEAELDEGFPEQFTDYDSVPQAELYVFCGNDGPGGSKYELFPDPLYIAEDEWETLKALGDPLQDRVVECCLDAENRWRLFRFRDDKNEANHTSTVSSVMASIRDGVSDQELLSAATAIKESWKIRAQKRKEQQQQQQPKH