Protein
Ribosomal RNA large subunit methyltransferase E
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Function
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
Sequence
MARDRRDYYYHQAKEEGYRSRASFKLKQINEKHNVIKRGDSVVDLGAAPGGWLQVAKQLSGGKVLGVDLQRIDPIEGVETIQGDINAESTIKKIIKIVGEKGADVVLCDAAPNLSGNWSYDHARSIELATSALECAKKILKPKGNFAVKVFQGDMFNDYLDEVRNNFVRVKAYSPQASRSQSAEIYIIGKKFLTAPLRKGDKFVVDIEKLGSSGDGAVLIEGFVVFVKEVEVGEKVRIKISDVKPNFAFADVEERIESSETENREKSD