Protein
Probable histone-binding protein rbbD
Organism
Dictyostelium discoideum
Function
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism (By similarity).
Similarity
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
Sequence
MTTQMEDVEEKVINEEYKIWKRHTPFLYDMVITHALEWPSLTVAWLPVKTSQPNKPYSIEKVILGTHTSDEEQNYLMVAKVHLPVDEASIESLKYDDTKGEVGGIGNVSEKIEIIQKINHEGEVNRARVMPQNHSIIATKTVSSEVYIFDTTKHPLEPTPDGKCSPNLKLTGHKKEGYGISWNPRKEGHLLSCSDDQSICMWDISAASKSDSTLDALNIYNGHTSIVEDVAWHYIHDTFFGSVGDDKKLMIWDTRTGTKPIHVVEAHNSEVNCLSFNPFCEFLVATGSTDKTVALWDMRNLGNRLHSLISHTDEVFQVQFSPHNETVLASCGSDRRVNVWDLSRIGEEQNNEDAADGPPELLFIHGGHTSKISDFSWNPNDPWSIASVAEDNILQIWQMAENIYNDREDDLENSKVTNAQIGE