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pytH

Gene
pytH
Protein
Pyrethroid hydrolase
Organism
Sphingobium wenxiniae (strain DSM 21828 / JZ-1)
Length
280 amino acids
Function
Catalyzes the hydrolysis of pyrethroids pesticides. Catalyzes the hydrolysis of cypermethrin to equimolar amounts of cyano-3-phenoxybenzyl alcohol and 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid. Hydrolyzes cis-permethrin at approximately equal rate to trans-permethrin.
Similarity
Belongs to the AB hydrolase superfamily.
Mass
30.012 kDa
Sequence
MTVTDIILIHGALNRGACYDAVVPLLEARGYRVHAPDLTGHTPGDGGHLSVVDMEHYTRPVADILARAEGQSILLGHSLGGASISWLAQHHPDKVAGLIYLTAVLTAPGITPETFVLPGEPNRGTPHALDLIQPVDEGRGLQADFSRLERLREVFMGDYPGEGMPPAEQFIQTQSTVPFGTPNPMEGRALEIPRLYIEALDDVVIPIAVQRQMQKEFPGPVAVVSLPASHAPYYSMPERLAEAIADFADAPAEYRQTATKAGPDRPAGADGGRADRADLP