Protein
Pyrethroid hydrolase
Organism
Sphingobium wenxiniae (strain DSM 21828 / JZ-1)
Function
Catalyzes the hydrolysis of pyrethroids pesticides. Catalyzes the hydrolysis of cypermethrin to equimolar amounts of cyano-3-phenoxybenzyl alcohol and 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid. Hydrolyzes cis-permethrin at approximately equal rate to trans-permethrin.
Similarity
Belongs to the AB hydrolase superfamily.
Sequence
MTVTDIILIHGALNRGACYDAVVPLLEARGYRVHAPDLTGHTPGDGGHLSVVDMEHYTRPVADILARAEGQSILLGHSLGGASISWLAQHHPDKVAGLIYLTAVLTAPGITPETFVLPGEPNRGTPHALDLIQPVDEGRGLQADFSRLERLREVFMGDYPGEGMPPAEQFIQTQSTVPFGTPNPMEGRALEIPRLYIEALDDVVIPIAVQRQMQKEFPGPVAVVSLPASHAPYYSMPERLAEAIADFADAPAEYRQTATKAGPDRPAGADGGRADRADLP