Protein
Tyrosine-protein phosphatase 2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.
Similarity
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
Sequence
MLHLLSKDEFNSTLKSFEEQTESVSWIIDLRLHSKYAVSHIKNAINVSLPTALLRRPSFDIGKVFACIKCNVKVSLDEINAIFLYDSSMAGMNRIYDLVQKFRRGGYSKKIYLLSNGFEAFASSHPDAIVSTEMVKESVPYKIDINENCKLDILHLSDPSAVSTPISPDYSFPLRVPINIPPPLCTPSVVSDTFSEFASHAEYPGFSGLTPFSIHSPTASSVRSCQSIYGSPLSPPNSAFQAEMPYFPISPAISCASSCPSTPDEQKNFFIVGNAPQQTPARPSLRSVPSYPSSNNQRRPSASRVRSFSNYVKSSNVVNPSLSQASLEIIPRKSMKRDSNAQNDGTSTMTSKLKPSVGLSNTRDAPKPGGLRRANKPCFNKETKGSIFSKENKGPFTCNPWGAKKVSPPPCEVLADLNTASIFYKFKRLEEMEMTRSLAFNDSKSDWCCLASSRSTSISRKNRYTDIVPYDKTRVRLAVPKGCSDYINASHIDVGNKKYIACQAPKPGTLLDFWEMVWHNSGTNGVIVMLTNLYEAGSEKCSQYWPDNKDHALCLEGGLRISVQKYETFEDLKVNTHLFRLDKPNGPPKYIHHFWVHTWFDKTHPDIESITGIIRCIDKVPNDGPMFVHCSAGVGRTGTFIAVDQILQVPKNILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQFKFLYDVVDYLNSGVNQASKPLMT