Protein
Dual specificity protein kinase pyk3
Organism
Dictyostelium discoideum
Function
Involved in the development. Negatively regulates tyrosine phosphorylation and activation state of dstC/STATc, probably by activating a dstC/STATc phosphatase.
Similarity
Belongs to the protein kinase superfamily. TKL Tyr protein kinase family.
Sequence
MDSFNNNNNNNNNNNNNNNNINGEGITLRTLLNSCTNTSSNEQLIVNNVNKNSNIINNININNTPSPISTCINVNKIELRGSSNGIFLNSKIKVPLPNSTLLEQQQDGADEQDKKQQSLSDKNILFSSGDKEFLNHGSNNIITDQNTLLYQLQQQQQKEKEKENDEIMNHDDIIGYNEENEDNFFNEGMDPILAHSIEHHLHNHHHHHGEFDTQENEDTSGESSDESENIDEVLVYTEDIESEKEKKRERLITSPPSFDPHTLYSMSQSLLNCSLNNNNNNNNSISSPSSSINNSGNNINLNNSGNNNVNSNNNTNIINNSNDNFISQPLFNPLSMPNNEQYELLPNPTTTTSTITSTTTTTTITNLPPALPSFPSSSSIKSLKNSFGSNSITSSGELNNVFSSSMSPPMSPPNRNVRSLTFPGTNPINCINTSVINSITANTNCINHHHHHHQHNHHNHHQGHNNINNSGHIRKSADDTVTLSPTLSSGSSSTSSSNPHHPNHNHQKGLNNKTLEKLSCTRKEIYELIEKKESLIEKQNLIDEGYSENADSFENLSEEIQKINEKIIELENLITSLSNSNSNWSLNGSSTSTISCNPLSPRSMNPSSSTSSTSSNLTNSLRKFSQELKIELRPLDLRAELYSSINTSPRGSASISGGSGSGGGGNNNGCFKTSSNSSINSPIQFFENENESIDSYEKKNEEQFESLTQLIRENQLYTKPIEFKEIKLLEKLESNSKSSNIWQIEYKSTQLVLKQPKDQDSDKNIEKRKQLFNGSNVSGSNNSGSSGGNNHNHHHCNNSNGSNSEVIPSKYTMIQHKNLGLLVGWCGDSIIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIASVMGLLHSKDVAHGNLTSRSIYLDRFQIVKVSFPKLNATDLNNPAIEPRYMAPEMTRMEEDQISCSIDVYAYAFVLWEALTSHLPFRKFNDISVAAKVAYENLRPKIPTSCPLIIRKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGILWSLNNDQEVERELQKKERFNEITEFLRGKKEIKFDEVAIVEKVGAGSFANVFLGIWNGYKVAIKILKNESISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPPCIFTEYLQGGSLYDVLHIQKIKLNPLMMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDDMTLSGITNPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTGKIPFEGLDGTASAAKAAFENYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETMKSKFIKQLSFLNDLIQNPDDDYNNNLNYDEEVDS