PUS10

Putative tRNA pseudouridine synthase Pus10

529 amino acids

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.

Belongs to the pseudouridine synthase Pus10 family.

60.244 kDa

MFPLTEENKHVAQLLLNTGTCPRCIFRFCGVDFHAPYKLPYKELLNELQKFLETEKDELILEVMNPPPKKIRLQELEDSIDNLSQNGEGRISVSHVGSTASKNSNLNVCNVCLGILQEFCEKDFIKKVCQKVEASGFEFTSLVFSVSFPPQLSVREHAAWLLVKQEMGKQSLSLGRDDIVQLKEAYKWITHPLFSEELGVPIDGKSLFEVSVVFAHPETVEDCHFLAAICPDCFKPAKNKQSVFTRMAVMKALNKIKEEDFLKQFPCPPNSPKAVCAVLEIECAHGAVFVAGRYNKYSRNLPQTPWIIDGERKLESSVEELISDHLLAVFKAESFNFSSSGREDVDVRTLGNGRPFAIELVNPHRVHFTSQEIKELQQKINNSSNKIQVRDLQLVTREAIGHMKEGEEEKTKTYSALIWTNKAIQKKDIEFLNDIKDLKIDQKTPLRVLHRRPLAVRARVIHFMETQYVDEHHFRLHLKTQAGTYIKEFVHGDFGRTKPNIGSLMNVTADILELDVESVDVDWPPALDD

Pus10

Putative tRNA pseudouridine synthase Pus10

527 amino acids

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity).

Belongs to the pseudouridine synthase Pus10 family.

59.71 kDa

MLPLTEENKHVAQLLFSSGTCPRCILRFCGVDLPAPYKHPSKELLNELQKFLEPEKPELILEAPNPPLKKIRLHEDGIDNLSEDGKEGVSVTEDESMAEKPSKLRVCNVCLGILQEFCEKGFITKVCQKVEASGFEFTSVVLSVSFPPQLSVREHAAWLLVKQEMGKQSLSLGRNDVVQLKEAYKWITHPLFSEELGVPTDGKSLFEVSVVFAHPETAEDCHFLGEVCRDCFKPAKNKQSVFTRMAVLKALSKIKEEDFLGQFPCPPNSPKTVCTVLEVECTHGAVFVAGRYNKYSRNLPQTPWIIDGERKMESSVEELISDHLLAVFRAESFNFSSSGREDVDVRTLGNGRPFAVELLNPHRVHFTSQEMKELQQTINKSSDKIQVRDLQLVTREAIGHMKEGEEEKTKTYSALIWTNRAIQKKDIGFLDDLKDLKIDQKTPLRVLHRRPLAVRTRAIHSMKTHYLDEHHFRLHLKTQAGTYIKEFVHGDFGRTKPNLGSLMNVTADILELDVESVDVDWPPALDD

pus10

tRNA pseudouridine synthase Pus10

519 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

60.469 kDa

MDYENKILQKYNLCNRCYGRIYAKLMRMGNKDRGTSIKTVIAMNFEEKLKDLIEEKNNLIDIISNSQDINENEEIDENTKNNEDTENKADDKSQSNEEKIQEIDEKINIIKENLTLLRKTGLNGIKNEYIIEELLKDDITREENESEENESNIFLTPEQKCPWCKDVFNIQNLEEIADKIVEALSEYEFDRFLIGTRLPKRIKELEKDLETTFNEKNTESLRNEFGRELGKILTKKLEKPVDKETPDIVVMVNPYNQKIYLQINPIFIKGRYRKTKRGIPQSHWDCRSCRGKGCEKCNFTGKQYPTSVEEIIAEPVMNIAKGSGEALHAAGREDIDVKMLGKGRPFVIEVKEPKVRKMDLLKIMDEINKIEGVEVSDLEYGVKNDVRFFKNEPHTKTYCALVSIVDEELENHDFENDKIVELSEKLENLRIDQRTPHRVSHRRADLVRVRNIYKAWCEPIDEKSFKLTVYCDGGLYIKELISGDEGRTKPSISEILDIPCYCKLLTVMEVHDENNPANY

pus10

Putative tRNA pseudouridine synthase Pus10

515 amino acids

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

58.59 kDa

MLLIEEKYRSVAQVLLSSGTCSRCVLRFCCVGSPANYRLPCKEVTYELQKYLSHGDPAEENDTPPSKKAKIEEDTSSNEHLGNCEDVNGSQVVRICPLCLGILQQFCEPEFIEKVFVKINSAVYELKDFVLSISLPAQLSVREHSAWLQAKQEMGKHGHSLDKTDIVQLKEAYKWIIHPLLSDQLGIQADSKSLFEVAVVFTHPETDGDCHFLATVCRDCFKPTKNKQSVFTRMAVVKALEKIKEEDFRVQFPFPPSSPETTCEVVDIQCNHSPVFVAGRYNKYSRNLPQTPWIIDGERKIESSVEELITDHLVAAFRSSSFNFSSSGREDVDVRTLGKGRPFAIELLNPHKVQFTGQEIKALQQKINTSDKIKVRDLQIVSREAVAHMKEGEEEKTKCYCALIWIEKMVRNEDLQLLDGLEELTIAQKTPLRVLHRRPLASRSRTIHTMRTEYVDEHHFRLYLKTQAGTYIKEFVHGDFGRTKPNVGSIMETNADILELDVESVDVDWPPSLDD

Pus10

Putative tRNA pseudouridine synthase Pus10

500 amino acids

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

56.763 kDa

MKNQDLVEYLRSCGVCEICQLRYLKARGAEYRNINETLQKLDVKLNENVENEELVISEGSQPSKRARLGVCSTCLGLFSKDFQNELLSSILASDFAKYDCQKIVLAICLPMSLQLRQLAMWFALRRRFGPSIDENNPPDVPIKEAVKLILHPIICEKLAKVYDANGLMINIDLTHSLEGEEVEKLVKLNKEAFPAKASHQKRIEISRGLLEKQYQPSKVKAETYEKYFQIPCSNVEESIKLTSIDLQGPLICVAGRYRKLSRELSHTPWILNGQRLMEDSIEEIIIRHVGPHFTEKLGKITFMSSGREDVDVRCLGKGRPFVLEIPNAKRSCLTKDEAFAMERAVDASGMVSIHHLQVVPREELTHIKTGEEQKKKFYRALCALQEPVSVKILEQLQISASFNIQQKTPIRVLHRRPLHTRPRTIYSVTAKVHRGNPKALIIDIVTQAGTYIKELVHGEFGRTTPSLSSIIGKPMDIQALDVVGIDLDWPHEVDNSKHKE

pus10

tRNA pseudouridine synthase Pus10

454 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

52.927 kDa

MASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKALELEAKIKKAKEKGINYEEELELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEKLLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFMESIKQEFGREFGKMLAVRLDKAPDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNYTGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINKDGRVEVLNLEFGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHFEMIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG

pus10

tRNA pseudouridine synthase Pus10

452 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

50.596 kDa

MPSENPTDNCIASDLISTAVRILRLGPICDSCFGRQFAMLGTGMTNSERGRSIKTLMVMSADLQASDESREMLRALAPSCRQARLRLGVEGDDENCWVCLGQMYPERLEELADRAVDELKGIECSRFLVGTFMSGLLAENEELLLADGCSRHAEPMKSEINREVGKLIALKSGKQPDLNNPEVVVHLHLSDGHVEIQIQPLYIYGRYRKLQRGFPQTRWPCRVCGGRGCERCGNTGRMYQESVDELIRGPIVEAADAEDTVFHGAGREDIDARMLGSGRPFVVEVVRPRRRDLDLNALRDEINRRCSGKVEVSDLIFVDKSMVEMVKNERFEKTYEALIEFSVPVEEEKLKSALSRLIGFVEQRTPTRVSHRRADKVRRRAVHSAELEEFSGRTARITVRCDSGLYVKELISGDAGRTRPSLAELLESDARVVELDVIDVGGVPNAKITRIS

pus10

tRNA pseudouridine synthase Pus10

444 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

50.205 kDa

MSTGTSASYKRDNAFYALDKVERILLDGYSLCDACTGRLFGLRGYGLSNTERGRALKTLLIMKAFQASPRQADLELLRVLARTGFEPARELLKKLSGEDVEVKACSICEGLTGRYYELALRAVEEAKSYEFNTFEVGVRIDAEVIRREEELWRRYGLESAESIRNEASREVGKIISKLTGKEYSRNNSELLIIVDLSAGAIELHPAPVFVYGRYRKYARGLPQNPWPQPDERIKFNTSIEELIVKPALELFEAEKAKFHAAGREDIDVRTLGTGRPFVLEIKKPRKRNIDLKVLAEKINSGAGGLIEVLDLAYTDRKTIKKLKSLASIAKKAYVARVKFEKPVDDEKLAEISKVFSNAVINQRTPTRVLHRRVDKLRKKIVYRLEARKISQDEVEFYLETQGGFYVKEFIHGDNGRTTPSIAEFLGNNVLSIELDVVSIEETAA

pus10

tRNA pseudouridine synthase Pus10

441 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

50.097 kDa

MGGSSISTPLDFNKIVEDVEKTLSKYPLCDHCLGRFFAKYGLGLSNRERGSSLKTMLGFKLYDDYSSKRIGRDSLLALAENAGEPLTRMVEKLFAENVNPKTCFICGGRISDEWLDSVAEAVYEKLKEASVTRFVVGVKLGRNLREKELQLVTETGFTRAESLKNEIKREVGKKVMAKYGLVPDFEKPEATAIVKLDENFNYRVELVITPVLLKGVYNKRGRNISHVPWLAKQGGRKYPLSIQEYLESRLADPFKAKKVKIHAAGREDVDARTLGPGRPLVIEIVEPLVRSYDIEDVNKLIRSDLVEVRVHKPASRRDIELLKQTSREKRKVYRLLVVSSTPISEAQLNELEAYFNDIAIQQRTPIRILTRKKDVLRVRKVYEVRTKPVSSTSFEALVYCDGGLYVKELVHCDQGRTNPCFASILNTELKPVELDVLYIEH

pus10

tRNA pseudouridine synthase Pus10

437 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

48.151 kDa

MDSRVLESALRALSRYPLCDRCLGRLFARLGRGWSNRERGEAVKRVLVMELHRRVLEGDEAALKTLVSAAPNIGEVARDVVEHLSPGSYREGGPCAVCGGRLESVIASAVEEGYRLLRAYDIERFVVGVRLERGVAMAEEEVKLAAGAGYGESIKAEIRREVGKLLVSRGGVTVDFDSPEATLMVEFPGGGVDIQVNSLLYKARYWKLARNISQAYWPTPEGPRYFSVEQALWPVLKLTGGERLVVHAAGREDVDARMLGSGRPMIVEVKSPRRRRIPLEELEAAANAGGKGLVRFRFETAAKRAEVALYKEETARVRKVYRALVAVEGGVSEVDVEGLRRALEGAVIMQRTPSRVLHRRPDILRRRRLYSLDCSPLEGAPLMECILEAEGGLYIKELVSGDGGRTRPSFAEVLGREAVCIELDVVWVEHEAPAAPG

pus10

tRNA pseudouridine synthase Pus10

436 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

50.019 kDa

MIDRLREALKRFNPCDSCLGRAFGYGLTGLENRERGRAIKLYLGMRAHLEGEEETLELLARSGLEEAAAVLDDPPEPEPCGVCRGVLDKVDEFAEVVACELKDLEFRGFVVGSRWPEEIRKAEKELWETLGVEGEPIKREFNREVGKRVEHLLDVRADPRNPDIEVVFDFRPSLEDPKFEVHVRPIYVRGRYLKLRRGIPQTKWPCPRCRGAGCPNCDFTGKLYTESVEELIGMVLKDAFLAESHKFHAAGREDIDVRMLGNGRPFVMELLYPKRRNVDLKEIEGEINRKVGDDVQVVGLEYGDPEDVGKVKDLSERSRKRYRAWVKFGKPVPEDKLREVLKGLERSVIEQRTPRRVLHRRADKVRRKRVHEAKLIEYDGDRAVIEFLCDPGLYVKELISGDAGRTRPSLAELVEVEAECERLDVIEFLDEGGDRS

pus10

tRNA pseudouridine synthase Pus10

430 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

50.02 kDa

MSIIDIANNILRKYCLCDRCLGRLFASLGRGLSNDERGKAIKIALVLELHKRYLDGDKDSLKQLVELSPNIGPIAVNLIKNLGIEIEYTPRTCFICDNKINDIIDTYSQRIADIINERHINSFVLGIRGVTSYIRKEESIANEFKLLYWENIKRELKREIGKKIQMMTNAKVDFLNPEAMIIIDIDRDRIYIESPSLLIYGRYWKLGRMISQNIWLTKNGVKKYPLSIEEIAKMLVKDGFGDDVVLHIAGREDVDVRTLGSGRPFVLEIKRPRKRNIDIKDIENRLNSISRWLKFELNMFVDRDFVSRVKKGCRTSYKIYRAIVVADRDIGIEDIKRLEEFFRDRIIEQRTPTRVLRRKKDVLRRRKVFEIKTRVISPRVFEALIKCEGGLYVKELISGDNGRTVPSFSSVLNANTLCLTLDALYVHEYI

pus10

tRNA pseudouridine synthase Pus10

427 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

47.333 kDa

MDVLEVAARATGTGPVCDACLGRLVADRSFGLSNAERGSALRTSLALRDDEDYEPVETADCWVCEGRCTEFDEWAERAAEAVEDVEFATYNVGTRPPPLIEENEALLREEAGLDDDAGEPFKSEFNREVGKRFGRLTETEVSFDRPDVQFTIDLAEDEIDAKVNSTFVYGRYRKLERDIPQTEWPCRECKGSGRQGADPCDHCGGSGYLYDDSVEEYTAPVVEDVMDGTEATFHGAGREDVDALMLGTGRPFVIEVEEPRRRRVDTDRLQADINAFADGAVEVEGLRLATYDMVERVKEHDAAKRYRAEVAFDADVDADALAAAVEELEGTTVEQYTPNRVDHRRASITRERDVYEATAELDDARHAIVEIHGEGGLYIKELISGDEGRTEPSLAGLLGVGAEVTALDVVAVEGEDEPFEREEFFRE

pus10

tRNA pseudouridine synthase Pus10

412 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

46.904 kDa

MSIERAMDILRKYPLCNHCLGRLFARLGTGLDNEERGRAIKDYLLMRIHERILNEGLSDELLNDVKALAVSGHEPSIKFLSNMGINVSPARCYVCGDTIFNRLNEWVNNIVNSLRSLGIEFRSFRLGSRVPLDIQNRELSITTEFNISSAESIKREINRELGKRVSAMLGVSFNREEPDVEVVIDVNTGSVEVQIMPIYISARYRKVHRLINEEGQVKWPIDRVIQAYNAQDVVIHTGGEDPMGVRVLGNGRPVILQVVKPSKRPDVNDVYALLKDSGYDIVLDNLSRVRASAVVKMKARVRDYVITYRVLAITDNSVTNENIKSLHDYFRNRQVVQVFRRGRRIRRRISMVYELDGRVIRDRLVEFLIRCQGNLYIRGFVHGGLGDVEPSIAGTLGFSVRPVEIDILNISD

pus10

tRNA pseudouridine synthase Pus10

411 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

46.535 kDa

MELISKALEAVRRYPLCDSCLGRLFALMGYGIENRERGQAIKTILHMAAVSDYRKGKDVTADLIALAKCHLPTRRFLAGVGIRVDEERCYICGDLMEGVEKYAEMAVEQLRGLDFVSFAVGSTLPEELLEKEAEVVKSLLVTTGESVKHEVNRRIGKELLRRLSDKRVDKLRPNVVVNVDLVSGQVKVVRNPILIGGRYLKLGRKIAQAKRFGNVRTTLLEKLAYLRDTFGGEDHVIHVSGREDSDARMLGSGRPLVVEVKQPLRYTAQVAPFRDKDVIFLPVGFTDRNEVRRLKEKAKTDIKLYRVLVLSESPLKQDDLSKLSALSGATVTQYTPRRIKRLHPRKKRVRMVYDVAWRLVSPHVFELYIRCQGGLYVKEFVHGDGGRTAPNVAELLNTRLEVLELDVLYIE

pus10

tRNA pseudouridine synthase Pus10

407 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

47.445 kDa

MTEKEYNTRQTQNYALCPKCLSRIYRNPKDRDNSIIPLINNTQKCSICNNLLLNEDKIFKLILKKIKMLKIEFDTFLIATQINNQTITKNQKEIYKITNYHGNNDIKHQIRRDISRLIEEKLGKTYDYKNPEVVIMVKIRKKPYKHNPYPEISNVNIFIDSNPIFIEGKYRKLVRGIPQTKWPCTHCKGKGCEACDYTGQQYKDTVEDLISREILPMTNGNTTKFHGSGREDIDVRMLGEGRPFVIEVKHPFKRKIDLKFLRVLVNSHSDGKIEINDLKYVTKERKASIKNSSVESYKIYSAIAEFENGVTSKDIYNIEKLKTIDQRTPIRVEHRRADLIRTREIKNIEVERINSKKLHLIIKCQGGLYIKELISGDNNRTKPSVSSITNNQAECTQLDVLKVHIPE

pus10

tRNA pseudouridine synthase Pus10

402 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

42.855 kDa

MRPERGYVLCDPCLGRLFGSGNILHCEKRGRIIRGKGRDRPSECHICKGLCPSLEESCGPSLWGAAAYEFETFVVGVRLKSSMAERDDEVRSRCRLAGAAALRAYVAAMLSSYLGAMTGASVDHGAPELSITADLRDNTAEFHPRPVVLSGRYTKSVRGLSQKGAPCGGCAGEGCTSCGMLGVDTGGSVEGVISGHACGTYSARRASFTWVGGEDQESLVGGRGRPFVAQLVQPHRRGLVHPATVRLGGVVLHGLREVRSMPQLPVRFRSKVRLAVSAKGEISDDTLGRLADLGGSTLAVYEGRRRVERAIHSASHSRTGPGSFELHMEVDGGVPFKRFVSGETVFPNLSDLLGTVCSCGGFDFEEITVERGGHPGARGGTRRRPRKGPARPAGGRDRPRKT

pus10

tRNA pseudouridine synthase Pus10

402 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

45.699 kDa

MDVQERLDAILDITDSKICPHCLGRRFSDVMEGPGNRLRGERLVEKFSLHLEGPCLVCGDVFERLDEAALRVREKVDDLNLEYSSVLVGTRLPDDVLRIDEEIDRRLGIQVEGIKREVNRELGKRVTSILRCPADFESPDLVITVDLRGQIRVHVQINPIFIEGRYRKLVRGIPQTKWPCRSCRGRGCSRCDYTGKMYPTSVEELISEPVLEATGGSDSKFHGSGREDVDVRMLGTGRPFVLEIKEPAIRTPDLRALEDEINRRARGMVEVADLRFSSRNRKVELKESSRKKYKVYRAIVELEGAVSDEDLVKLEKLDLIRQRTPLRVSHRRADRIRERRVLEISWKRLDDHLELIIKAEGGLYIKELISGDSGRTEPSVSSILGVPARCASLDVLEVGEPA

pus10

tRNA pseudouridine synthase Pus10

401 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

44.601 kDa

MSIIEDARKALLKYPLCDHCLGRLFASRGLMISNEERGRSIKNVLFMESLNSSTGTYNEDTLVALAKSGHRESLLFLRRMGKVIEQQPCFICGNLFDKININDIVSKVEEEINRQGIEFNSFQVGSTVNKGVIENEVKVSTELGITSSESIKRELNRLIGKVLADKLGKRYSRLNPDVVIKVNTSDGSVSVEVMPIYIEARYRKLIRGIPQVGDSSVASVAREVVSELRPLNVVLHFAGIEGPEVRVLGLGRPMIIEATRPLRRSLPGGIITRHGVQLLNLKAAGKVQVREIKSKAGELRRVFRILVKLHGSVTDEQLRSLEDYFSNRQIRQSMGKGRRVKLIYGLKVVPVHGSILELIVNTQGGFSVRRFITGEGTEPSVSGTLGIKVTPIEIDILNIWH

pus10

tRNA pseudouridine synthase Pus10

400 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

43.128 kDa

MNEDPAQQAMKVLAKYPLCDRCLGRLFAGLGRGLSNAERGRALKLSVVMSLHAMSLSGRLPENARDVLANAGGAAAQVYVELFGSPPEHRSCYICNDALDKFLDEMPQRVADAVKEWGGSTFLVGAKVDPGVIAREERIKAEFGLAFGESIKSEIKRELGKRAQQLGPKVSFDRPDVVVMVSFPDGSVSVQPRRLVVKGLYRRLRRDLQLRPREALSHPLVARLINDTRSSRVGIVGLVRDEKEVRALGLGIPVEFHLGGPRVRLVPPDGSIIEAEGASLEVNSSVEASGPEDLSRRVRVYRCVLYVEGGAFESLQLAAASLRGKEVRQKFMGKEVSGVVRGAECVDMGGGLAECIIALDERLHVMELVSGSGTEPSLSGLLGTAAECVVADLLGVIPLR

pus10

tRNA pseudouridine synthase Pus10

389 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

44.511 kDa

MFQISELANYRLCKRCSGRIFAYHYHGISNLERGEYLQFAIGCETGNPDFSFVDSKNCDICHGIFDRFDDIYDLVAKKVGDAQYSTFLVGSVFPQDTIRMEEDIQKKFGSSGESIKKEFNREFGKYFSARTGKEYSQDNPDLTILVNAEYLFVDVKIRSIYIYGKYRKFRRDMPQTRWIHRPNGDTVESVIGSVFTRYAGGTNYYLHGSGREDVDVRMLGNGREFVLEVENPRYREFELDPVVKEINTSGKGVEIFDVKFSSHDAVSEVKLEKHRKVYDALVVSDRPIDESRLLEACINLTGKNIYQRTPLRVAQRRSDLVRTRRIDQVDLVGVSANEAEILISAEAGTYIKELVNGDGGRTRPSLSEMYGSPLNVKELDVIKICRGED

pus10

tRNA pseudouridine synthase Pus10

388 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

44.68 kDa

MILEKAREILEEHQLCNHCLGRLFGKLGKGTNEERGRAIRLLLSMETGKEYKEPEKCELCGGVFNNLDKFAELCIKAAEGIEFETFWVGSRFPEEIEKKEEEIWRKFRVVSGEKITKEFNRELGKVIAVRYGKTPVKERPDVVFIVEPFSEKVELQVNPIYVAGRYRKLIRGIPQTPAPGFKESIATIICRAFKKHFHGKCIFKGAGREDVDVRMLGNGRPFVVEIKRPRKRKVNLKDIEEEINQSGKVEVLNLRFITPEEAERILTTRHRKVYEAIVYVKDGITKEEVEKVVKSLKNAEIKQRTPRRVLNSRADLVRVRKVYDVKGELIDDKHFKLRLVTDGGLYIKELISGDRGRTTPSVSEILGKEAWCEILDVLEVLDDVEGDN

pus10

tRNA pseudouridine synthase Pus10

381 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

43.236 kDa

MTTYQKIIPIANQILKKYDLCDHCLGRLFTKQLYLSSNKLLGKKLKKNSKSSQRCYICKNLFDNLNYFLNMMIDSASHYSYSSFSVGATIKPSIIDRDDVIRSKYKLKGIDGIKTDVTKELGKLFSKKTKKSFDSLDPEIVFTVNLKDEFCDIRSKSLTLSGRYVKPVRGFLQKQKSCSNCSGKGCRICDFHGIKEFDSVEGEISQFLFKKLGGTTAKFTWIGGEDKSSLILGTGRPFFVKIQNPHKRKLRAKSANLEHIKVSNFKIVADSPKKPLKFNSSVEARISTSSIIDAKLLRKLKNLTKKPIAVYEKSGKRSEKRILSIKYKKSDETSFTLFFKFEGGLPVKRFVTGDDVSPGISQILDMSCKCLEFDFHDVEVK

pus10

tRNA pseudouridine synthase Pus10

377 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

43.311 kDa

MDLKELFDLNLCLRCTGRIFAAVDTGLTNEERGARLYFAYKSIYGERDVPESCYLCNGVFKKFDEFFNILMSKLNNYEFNSILVGSTFDENIIEMEKDIQSRFGSKGESIKKEFNREFGKYLSKRLGKPFSKDADLTIEVDALYENVNIIVKPVYIYGVYIKKSRDISQTRWIHKTGESIESIIGNELRSMTGCENYYLHGSGREDVDVMMLGNGREFVIEAAMPKRRYIDLYELQLRVNASGILFIYNLSYSSKATVRRIKSELHEKLYIAEVTGDLNKDIKKACSKFNNLIIEQRTPLRVINHRSDLVRRKKINYINIISIMNGRALLKICAEAGTYIKELVNGDNGRTVPSLSSVYGSQLQVSSLDVVKIYRDD

pus10

tRNA pseudouridine synthase Pus10

373 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

41.854 kDa

MGKPVDDLLNSLMNLLDSETPSGGGCHLCDGLLSRELGKMLRKALSELEGVELSSVKSGVSLPAILIEREDRIRANHNPPKMRSLKVTLTRLLDVAISSLTGLKVSQEPDAILIFDFERGDVKLELAPVFIFGRYRKLQRGISQSRRKCPECGGRGCEACGWKGKIPQGSVEGIVGEVMREFFSAEDYVLHGAGREDVDARMLGEGRPFVMELLSPKRRSADLREVESEINRRAAGLIEVKNLEFSRREKIRILKERSPNVKKLYRALVEVEGGVEEGELELLKGLEGAVIRQRTPKRVLWRRADITRLKRVYEVNFRRIDDKKFELFVLCDGGLYVKELISGDDGRTSPSVTEILGKKSFCSELDVLEVMVE

pus10

tRNA pseudouridine synthase Pus10

357 amino acids

Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

Belongs to the pseudouridine synthase Pus10 family.

41.287 kDa

MNLCRECYGIIGEGVVAEKCEACCNAFDRVEEFAEEIVKKMSEYEFETFNVGSRVWGSLKALQEYLSLKGIEYEIKQRFNTKLARAIEEKTGSKRTLNPDITVLFDLETFTFELQIRPVFIYGRYLKRVRNISQTRWLCGYCNGEGCEVCNFTGKKYVSSVEELIAMPAVRLFKARDAKLHGAGREDVDARMLGTGRPFVLEVIEPRKRFVDLKELEEAINSQKWVAVRDLEYTDAEKVREVKTERHRKTYRAKVVFEEKVERERLIEALESLKGEIRQRTPMRVSHRRADRVRVRRLYDARLIHHTGRVAVVEFEAEAGLYIKELVSGDNGRTRPSLAEKVGVNARVDRLDVIAVS