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ptsH

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Length
109 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
11.597 kDa
Sequence
MSGGNDSVLHRPVEAPLMEDGELSAVFTIRNSSGIHVRPAGTIVKLFEGEECEATLTYLGKTVNARSVMSILMLGASYNGEVAVHIKGPSASRVMQKLSEVFNSGFGEL

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Chlamydia pneumoniae
Length
108 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
11.86 kDa
Sequence
MNEPTRTYLESEKDTQDQIEELQATCIVKNAAGIHVRPAGVIVRLFDGEPCDVHFTYAGKTINAKSIMSILMLGAPQGGEILVTIRSKEAHRILQKIQDAFSSGFGEL

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Length
104 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
11.148 kDa
Sequence
MSGGDDLVLHNPVEDGELSAIFMIRNPSGIHVRPAGTIVKLFDGEDCEATFTYLGKTVNARSVMSILMLGASYNGEITVRIKGPSASRVMQKLAEVFNSGFGEL

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
93 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.391 kDa
Sequence
MAERRVNVGWAEGLHARPASIFVRAATATGVPVTIAKADGSPVNAASMLAVLGLGAQGGEEIVLASDAEGAEAALERLAKLVAEGLEELPETV

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
90 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.702 kDa
Sequence
MPALEITIINKLGLHARAAAKFVGVAGRYPCQVRVGRNPESCVDGKSIMAVMMLAAGKGTNLHLHTEGEQEDEALNALVELINNRFDEGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Pseudomonas putida
Length
90 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.6 kDa
Sequence
MPAREITIINKLGLHARAAAKFVGVAGRFPCQVPVGRAPDKLVDGKSIMAVMMLAAGKGTQVHLHTXGEQDSDAMDALVELINNFFDEGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154)
Length
89 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.418 kDa
Sequence
MAKFSAIITDKVGLHARPASVLAKEASKFSSNITIIANEKQGNLKSIMNVMAMAIKTGTEITIQADGNDADQAIQAIKQTMIDTALIQG

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
89 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.693 kDa
Sequence
MLKQSIEIINKLGLHARASNKFTQTASQFKSEVWVTKNDSRVNGKSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
89 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.693 kDa
Sequence
MLKQSIEIINKLGLHARASNKFTQTASQFKSEVWVTKNDSRVNGKSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Xylella fastidiosa (strain 9a5c)
Length
89 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.875 kDa
Sequence
MLEHELIVTNKLGLHARATAKLVQTMSKFQSNTTLSTKGREVNAKSIMGVMLLAASQGTVIRVRIDGEDEHTAMQALSELFENRFNEDT

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
89 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.863 kDa
Sequence
MLEHELTVTNKLGLHARATAKLVQTMSKFQSNTTLSTKGREVNAKSIMGVMLLAASQGTVIRVRIDGEDEHTAMQALSELFENRFNEDT

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.321 kDa
Sequence
MEKKEFHIVAETGIHARPATLLVQTASKFNSDINLEYKGKSVNLKSIMGVMSLGVGQGSDVTITVDGADEAEGMAAIVETLQKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Geobacillus stearothermophilus
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.167 kDa
Sequence
MAEKTFKVVSDSGIHARPATILVQTASKFNSEIQLEYNGKTVNLKSIMGVMSLGIPKGATIKITAEGADAAEAMAALTDTLAKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Lactobacillus casei
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.254 kDa
Sequence
MEKREFNIIAETGIHARPATLLVQAASKFNSDINLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADEADAIAAITDTMKKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.179 kDa
Sequence
MASKEFHIVVETGIHARPATLLVHTASKFTSEITLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADADDAISTIAETMTKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Lactococcus lactis subsp. cremoris
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.126 kDa
Sequence
MASKEFHIVAETGIHARPATLLVQTASKFTSEITLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADADDAIATIAETMTKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Lactobacillus sakei
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.338 kDa
Sequence
MEKRDFHVVADTGIHARPATLLVQTASKFNSDVNLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADEADAINAIEETMKKEGLSE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.404 kDa
Sequence
MEQASFVVIDETGIHARPATLLVQAASKYSSDVQIEYTGKKVNLKSIMGVMSLGIGKGADITIYTEGSDEKEAIEGLTEVLKKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.404 kDa
Sequence
MEQASFVVIDETGIHARPATLLVQAASKYSSDVQIEYTGKKVNLKSIMGVMSLGIGKGADITIYTEGSDEKEAIEGLTEVLKKEGLAE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Lysinibacillus sphaericus
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.45 kDa
Sequence
MKTQQFTVIDPLGIHARPASQLVAKATPFASAIEVRTEEKAANLKSILGVMGLALKQGSQFTLYVEGEDEDQAFEALATLLTEMGLAQ

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.41 kDa
Sequence
MKKFQAVIKDPVGIHARPASILASEASKFKSELKLVAPSGVEGNIKSIINLMSLGIRHNDNITIKADGADEEEALAAIKACLEKNKVI

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.495 kDa
Sequence
MKKIQVVVKDPVGIHARPASIIAGEANKFKSELKLVSPSGVEGNIKSIINLMSLGIKQNDHITIKAEGTDEEEALNAIKAVLEKHQVI

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain COL)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain N315)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain MRSA252)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain MSSA476)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus aureus (strain MW2)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.496 kDa
Sequence
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus carnosus
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.511 kDa
Sequence
MEQQSYTIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDEADAIQAITDVLSKEGLTE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Staphylococcus xylosus
Length
88 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.553 kDa
Sequence
MEQKSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDETDAIEAITDILSKEGLTK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Treponema pallidum (strain Nichols)
Length
88 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.527 kDa
Sequence
MVVKTVRVLNRAGVHARPAALIVQAASRFDSKIMLVRDTIRVNAKSIMGVMAMAAGCGSELELVVEGPDEVAALSAIERLFQNKFEEE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Bacillus megaterium
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MAQKTFTVTADSGIHARPATTLVQAASKFDSDINLEFNGKTVNLKSIMGVMSLGIQKGATITISAEGSDEADALAALEDTMSKEGLGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Bacillus subtilis (strain 168)
Length
88 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.
Similarity
Belongs to the HPr family.
Mass
9.189 kDa
Sequence
MAQKTFKVTADSGIHARPATVLVQTASKYDADVNLEYNGKTVNLKSIMGVMSLGIAKGAEITISASGADENDALNALEETMKSEGLGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Streptococcus equinus
Length
87 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
8.937 kDa
Sequence
MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNLKSIMGVMSLGVGQGADVTISAEGADADDALAAIEETMTKEGLA

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Length
87 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
8.936 kDa
Sequence
MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNLKSIMGVMSLGVGQGADVTITAEGADADDAIAAINETMTKEGLA

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Streptococcus salivarius
Length
87 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
8.907 kDa
Sequence
MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNLKSIMGVMSLGVGQGADVTISAEGADADDAIVAIAETMTKEGLA

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
87 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
9.124 kDa
Sequence
MAEKTFTITAETGIHARPATQLVNKAGQYSSEITLEYKGKAVNLKSIMGVMSLGVGKGAQVTIKAEGSDEAEALKGIEEVIKEGLGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Bacillus thuringiensis subsp. israelensis
Length
87 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr mediates glucose catabolite repression of cry4A toxin expression.
Similarity
Belongs to the HPr family.
Mass
9.238 kDa
Sequence
MEKIFKVTSDSGIHARPATLLVNTASKFGSDINLEYNGKNVNLKSIMGVMSLGIQQNAEIKITANGDDAAQALAAIEETMKNEGLGE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Length
86 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.386 kDa
Sequence
MVKKEAIIKAVNGLHVRPASTFVKKAKEYSSEITIESDGKSVSGKSLFRLQTLELSSGKKLLICAEGEDEEIAASELAELIESFKE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.304 kDa
Sequence
MFQRDIKITTPNGLHTRPAALLVKEAKKFISEINIISNGKSANAKSLFKLQTLGLVQNSLITISAHGIDEKVAVEDLAKFLTTLK

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Escherichia coli O157:H7
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Escherichia coli (strain K12)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.004 kDa
Sequence
MYSKDVEIIASNGLHTRPAAQFVKEAKAFSSEITVTSGGKSASAKSLFKLQTLALTQGTILTISADGEDEQQAVEHLVALIPTLE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Klebsiella pneumoniae
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTLSAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Salmonella typhi
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Shigella flexneri
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.119 kDa
Sequence
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.109 kDa
Sequence
MYEKQVEITAENGLHTRPAAQFVKEAKAFDADITVTSNGKSASAKSLFKLQTLGLVKGTVVTISAEGPQAKEAVEHLVALMDQLH

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.412 kDa
Sequence
MFQNQVKITAPHGLHTRPAAQFVKEAKKFTSEISIIYNGKSVNAKSLFKIQTLGLIQGSLITLSAEGEDEKKAIEHLSLIMTELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
85 amino acids
Function
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Similarity
Belongs to the HPr family.
Mass
9.571 kDa
Sequence
MFQKEIKINALHGLHTRPAAEFVKEAKNFISDIHIIYHGKSVNAKSLFKIQTLGLVKDSVIILSAEGEDEKKAVEHLSKIMTELE

Gene
ptsH
Protein
Phosphocarrier protein HPr
Organism
Streptococcus sanguinis
Length
19 amino acids
Function
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
Similarity
Belongs to the HPr family.
Mass
2.031 kDa
Fragment
single
Sequence
AIKVFHIVAETGIHARPAT