Protein
Pseudaminic acid synthase
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Function
Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid.
Similarity
Belongs to the pseudaminic acid synthase family.
Sequence
MQIGNFNTDKKVFIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQTYTPDSLTLNSDKEDFIIKGGLWDKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIASFEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAIEDMNLKGIVSLKEKFNVEVGLSDHSFGFLAPVMAVALGARVIEKHFMLDKSIESEDSKFSLDFDEFKAMVDAVRQAESALGDGKLDLDEKVLKNRVFARSLYASKDIKKGEMFSEENVKSVRPSFGLHPKFYQELLGKKASKDIKFGDALKQGDFQ