priS

DNA primase small subunit PriS

414 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

47.714 kDa

MDNRTARFLKTRFQKYYKNAEIGLPDHLPNREWAFIFFDSMPDKMMHRHKAFGSPGEALDYLYGMAPAHVYNSTAYYEYPDARKMNEKNWLGAELIFDLDADHLPDAPKNYADMLELVKKETFKLMDFLLEDFGFSEQEIELVFSGGRGYHFHVRSPKVLKLGSAERREIVNYLSGRDLDFKYFFREVAMDGEFGTGSKTFKGMKNVPFKCTLVGYDSGWGRRIALYLTDYMKAECGKRYKKDMFPELRRYEKVGDTTIKKLISLTNSENGLKDILEKGRLDFDVRNFKDIAAYFMRESVEDFLHRFGTSVDEPVTADIKRLIRVPGSLHGGSGMLVKKLALSELEKFDPLTDAVVFGERPVKVTVLKPFSVQLKGKDLRVEEGIQEVPEYAAVYLICRGVAEYGHRRNQPGPV

priS

DNA primase small subunit PriS

414 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

47.502 kDa

MDSRTTRYLKSCFQKHYKTAEIGLPDHLPNREWAFIFYDDMPEKMMHRHKSFGSPGEALDYLYGMAPAHVYNSTAYYEYPDARKMNEKNWLGAELIFDLDADHLPNAPRNYADMLELVKKETLKLMDFLLDDFGFSEQDIELVFSGGRGYHFHITSPKVLTLGSSERREIVNYLSGRDIDFKYFFREVSMDGDFGTGSKSFKGIKNLPVKCTLVGYDSGWGKRVALYLTDYMKAECGKKYKKDMFPELRRHEKVGDTTIKKLINITNSENGLKDILERGRLDFGVRNFKEIAAYFMQESMENFLNRFGASVDEPVTADIKRLIRVPGSLHGGSGMLVKKLALCELEKFNPLNDAVVFGERPVKITVSKPFSVQLKGKDLRIEEGIQEVPEYAAVYLICRGVAEYGYRRNQPDAV

priS

DNA primase small subunit PriS

414 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

47.615 kDa

MDKRTTQFLKSRFQSYYKNAEIGLPDHLPNREWAFIFYDDMPEKMMHRHKSFGSPGEALDYLYGMAPAHVYNSTAYYEYPDAKKMNEKNWLGAELIFDLDADHLPNAPRNYADMLELVKKEALKLLDFLLDDFGFSEQEIQLVFSGGRGYHFHIVSPKVLTLGSSERREIVNYVSGRDLEFKYFFREVAMDGDFGTGSKTFKGMKNVPMKCTLVGYDSGWGRRIALYLTDYMKRESEKKYKKDMFPELRRHEKVGDTTIKKLINIANSETGLKDILEKGRLDFDVRNFKEIAAYFMQESAEDFLHRFGASVDEPVTADIKRLIRVPGSLHGGSGMLVKKLALSELEEFDPLNDAVVFGERPVKITASKPFSVQLKGKDLRIEEGIQEVPEYAAVYLICRGVAEYGHRRNQPDTV

priS

DNA primase small subunit PriS

400 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

45.53 kDa

MNDQTRAFLRERFRDYYSRSKVFVPPGLAQREWGFIFHEETVGVAMRRHKAFNSEGELADYLRSMPPAHAYHSAAYYRHPQAPTMQEKDWLGADLIFDLDADHLPGVKNMTYGEMLDNVKVEIIRLIDEFLIDDLGFREKDMDIVFSGGRGYHVHVRDERVRTLKSPERREIVDYLLGTGLEPDRMFIRTNQRIDTGTTSVAGVWLIRGFDSVPGGWDRRVARHIVEKLDQIGRLPDKDAKEALRAFSLESKDVKRILHVARDPASLQKIREKGLIELSGNLEGFFRSILAGTIDQFKVSLAGKTDEPVTADIKRLIRLPGSIHGGSSFRVTPLTRAQLESFNPLEDAIIFSDDPVRVLVTRPAVVEMKGKIYRVSEGVGRLPENVAMFLMCRGSADYEP

priS

DNA primase small subunit PriS

395 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

44.848 kDa

MESKTSTYLRARFREYYLTASMDAPPGMEAREWGFIFYDTPGMRRHRSFRSRKELVDYIRSTVPAHVYHSAAYYLKPDAPTMKEKIWKGADLIFDLDADHLAEYRGSGIRDFREMLERVKGETMKLLEFLLSDFGFDERMISVAFSGGRGYHIHVRDKSVLKLRSDARREIVDYLTGRGLDPERFIHKIGVDGDAGVERARSLRGPASDAPGWGGRINKAIESMVMHLRELDDEEALRLLKNVKGIGKQKARLFLSQIREENAIKSIRAGNLDFFKHASGIWNLIIPYIMEETVRALGGETDEPVTADVHRLIRFPESLHGGTGLRVTSLSINSLHAFDPLKDAVVFGDDPVHVEIIRPTTLELMGERFDLLEGKTELPEYAAVFLLARGFAEVG

priS

DNA primase small subunit PriS

393 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.795 kDa

MNGRTREYLKGRFGDHYRRASLSPPPAANEREWGYITWGDGGTTMVRHHSYLDVTGGGDLGGFLAGERPRHVYFSAGRYDDPGASSMGQKGWRGSDLVFDLDADHLPGIDPSETSYAAMLEACKGALSRLLDLLVEDFGFEPLAVVFSGGRGYHVHVRRDDVLELDRTARREIVEYVLGEGLDFDDIVSTQAVAGSAGRSSPAQKRTLPDGGWAGRVRTRLTTLFDEVLTMEEAAALDRLREFDGIGEGKAKAALTAARNNREELTKGNVDVHPAVYSIARELFETVVEAESAPIDEPVTTDINRLIRLPGSLHGGTGLEVQHLDRDAIDAFDPLSDAVPETFVGNEIAIYTQEPTTVELRGESFRLSEGVSSVPEYVGVFAMARGYASKAGE

priS

DNA primase small subunit PriS

392 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.653 kDa

MEERTRAYLRGRFGDHYRQASVTPPPAANEREWGFIPWTEGPGETMVRHRSLLDLGEIEDFLGRRKPRHVYFSAGRYDEPSASTMSDKGWRSSDLVFDLDADHLPSVVLGEDSYAEMLAKCKDALRRLLDFLEDDFGFDDLTIVFSGGRGYHVHVRDERIRHLERDARREVVDYVRGIGLEFDELVDEESVAGTAGRSSPAQKRTLSTEGGWSARAHRHMLAVVDDLLAMEEADALEQLQEYDGIGEGKATAALNAARSNYEQLEAGNIDVHPAFYQLAKILLHEVVAADNAPIDEPVTTDTNRLIRLPGSLHGGSGLEVQRIDRDDLDAFDPLVDPVPETFRGHDITVEVTDGGLVELDGDSFTLEAGNQTVPEHVGVFLMARGRAEKGKE

priS

DNA primase small subunit PriS

391 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.35 kDa

MEERTRAYLRGRFGDVYRRAEIDLPPRADDREWGYIPWTAGPDTTMVRHKSTLDLGSMTSFLERKCPRHVYFSAGTYDAPGAATMDEKHWQGSDLVFDLDADHLPRVTLGEDSYAEMLSKCKDALLRLLDFLERDFGFEELTVTFSGGRGYHVHVRDAGVYELGSEERREIVDYVRGNDLALETLVEAEPVGGRGLENPTEKRMLPADGGWGRRVTTRLEAFADDLIERGEDDAVATLTEFDGVGERSARAIYNVVADNTTAVKRGNVDVHPAFLTVARRYIDETVAAEQAPIDEPVTTDTNRLIRLPGSLHGGSGLEVQRLDRAALDDFDPLVDAVPETFVGHDITVELPTEHTVELRGESLTVGPGVSTVPEYAGVFMMARGTAEKATE

priS

DNA primase small subunit PriS

391 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.35 kDa

MEERTRAYLRGRFGDVYRRAEIDLPPRADDREWGYIPWTAGPDTTMVRHKSTLDLGSMTSFLERKCPRHVYFSAGTYDAPGAATMDEKHWQGSDLVFDLDADHLPRVTLGEDSYAEMLSKCKDALLRLLDFLERDFGFEELTVTFSGGRGYHVHVRDAGVYELGSEERREIVDYVRGNDLALETLVEAEPVGGRGLENPTEKRMLPADGGWGRRVTTRLEAFADDLIERGEDDAVATLTEFDGVGERSARAIYNVVADNTTAVKRGNVDVHPAFLTVARRYIDETVAAEQAPIDEPVTTDTNRLIRLPGSLHGGSGLEVQRLDRAALDDFDPLVDAVPETFVGHDITVELPTEHTVELRGESLTVGPGVSTVPEYAGVFMMARGTAEKATE

priS

DNA primase small subunit PriS

390 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.866 kDa

MDLKTKYYLKSKFQEYYRTAKIHLPAKLPEREWGVLSFDDMPETVMRRHKSFGSAGEVEDYLTGMAPAHVYYSVAYYTYPNAPTMKEKQWLAADLIFDLDADHIPGAPNSYSDMLDHVKKETLKLYDLLTDDFGFKEEDIGAVFSGGRGYHFHISDPRVLSLESAERREIVDYISGRGLNLDKIFVKKGVSGDAGSEKATMNVFPSEDDGGWGGRINHHMIAYLRELAAKEDAEKLFTGFDRIGKKTAKRIVEILRDETQVDLLKKGNMEALSRVNKDIIQTLAERSVTELSASVDEPVTGDIKRLIRLPGSLHGKSGMCVTSLSISQLEDFDPLNDAIVFSDKPVKLKVIRTFAVQMKGKDLHVEEGVQELPEYAAIYLMCRGAAEYGP

priS

DNA primase small subunit PriS

388 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

44.179 kDa

MRPATRIFIKQRFTDYYDKARISPPSSVKEREFGFIFFDDRYPDDIRMRRHIGFSSGDEMQEYVKSLVPAHAYYSTAYYRTPQAPTMGDKEWLGADLIFDLDADHIMRGSYEAMLERIKGEAEKLLDVLDNELGIDMRTIKLVFSGGRGYHVHVQELAFRDFEPAERRELVDYVCGTGISPSLLLHDWKPGRRGWHDRFRLVLTRYLQDLSTRPIKEVKAELSSLRGVGQVMAERFAGMIPELITLLNTNPSSILLRDQTVRTVFGALTSERESTLLPHIREAAVQADEPVTTDTRRLIRLPGSLHAKSGFKVVPMEVKELHDFDPLIDAVAFGEREVIIESEREYSFSLLGSSYDIPKGRLKVPEAVGVFLCCRGMAEIGGVLDHAS

priS

DNA primase small subunit PriS

387 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.286 kDa

MDDRTREYLKGRFGDYYRRASPALPPDANLREWGHIPWTPGSGTTMLRHQSLYDLGDVDTFFADNAPRHAYFSAARYDDPGASTMSQKGWRSADLVFDLDADHLPGVDPDATSYPEMLAECKQALLRLLDFLEDDFSFDDLTVVFSGGRGYHVHVRDESVRELDSEARREVVDYVRAIDLDTEGLIRTVSERGTTKRVLRTEGGWGARVHEALIEYADDLREMDAEDARERLMELDGIGEGRAETILGAFDRNPTAVREGNVEAGGPGVRRLVSALAARVTATDTAPIDEPVTTDTRRLIRLPRTLHGGSGLVVTPIDRDDLDAFDPLRDAVPDRFVGREIRIETDVDRTVELNGERVRVEPGRNTVPEFAGVFLMARGEARKAPER

priS

DNA primase small subunit PriS

385 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.999 kDa

MEDRTRTYLKGRFGDYYARARMDTPPAANRREWGHIPWSAGSTTMVRHQSLLELGTLDDFLHRTAPKHVYFSAARFNDPGATTMDQKDWQSADLIFDLDADHLPGVNPDTTSYADMLTACKTELQTLLEFIDDDFNFDETQVVFSGGRGYHVHVRDEQVRSLDSAARREIVDYIRAIDLNIETLIETQSNHGTTQRILKHRGGWGQRIHKRLVELIETLQASDDTEALERLQSFEGIGTGRAETILGQIQNNPEAIHAGNLEAGGAGIRILADALAQTAFEAETAPIDEPVTTDTNRLIRLPGSLHGGSGLLVTPLDREEIPSFHPLEHAIADRFRGRDIQIRITDSGVTTFDGETFDITEGNKTVEECLGIFLMARGRAEKVTE

priS

DNA primase small subunit PriS

380 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

41.9 kDa

MKPATLEFLRQRFFAYYNGAIPGAGAGYSPESLTEREWGFLFFTENQRSGMRRHISFTSQDELTSYLKSMVPAHVYYSTAYYTHPGAAQMADKEWRGADVIFDLDADHIVRGPYDIMLARVKEELFKLIDMLTGELGFAKRDLRINFSGGRGYHVHLPLLSVRGWDTAERRELVNYVSGTGLSFDSMMAPSQKSGWKLRYHDALNDELARIAGLPCEDALSYLSGLSGISETFAAGFLKNISQTQNLLKSNPEKLLANKVVRAIANAENEPFQAGILSRAAQADEPVTTDVKRLIRHPGSLHGGSGMRVVPISVDQLDAFDPLIDAVVFGERNVSVDCAFNLSMPILGNNYTLTAGRNVVPEALGVFLCCRGIAELSGGI

priS

DNA primase small subunit PriS

380 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.814 kDa

MPRSQDPVMRTRRFLEHLTRKYYERARVKLPGDFSLREFALQTWTGKSYLRHLSFASTEAVHRLLVEKAPRHFYYSSARYDQPGADDMDAKGWRSADLTFDIDADHLPECSGSIVEVDGGIEGKTSFIEEALCMRAAALRAQILYDILVYELGFDKSRIAIEFSGHRGFHVTVYLDDFDDYAKAGSDVRREIVNYVKALGLRADVLEPWTMLQVRRGKPIPIPPNVQLAGARGRVARIIRRLALRDGAIDIVKAVEGPSTTYSEELREYEDKARQLIGVEIDEQVSVDVKRLIRVPYSINGKTGLLVKPVTVDELDEFVVDETLSPFAREPPVRIRVVTSLPSSVTILGNRLKLREGDSPRLPAPVAVYLMAKGVAVLAQ

priS

DNA primase small subunit PriS

378 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

41.967 kDa

MRPATLEFIKQQFTGYYQRVYPVTPDALLQREWGFIFFDAGREVRMRRHLAFGERQELTEYLKTMVPAHVFYSSAYYESPGAPTMAEKGWSGADLIFDLDADHIMHGSYQAMLARVKEEVQKLLAVLTDELGFSEKYCEVVFSGGRGYHIHVNDLAVRSWGSAERREVVNYVCGIGLDPGLLIRAGTDLSTGWPRRYLGALDGYLAWLKVKNQKDALLHLSSIKGVSRSSAAGLLKSLDQVRATIGGDHPEKVLGDRVLRAVTTNDNPDWKKRLQETGVQADEPVTTDIKRLIRMPTSLHGGSGLRVVPLTISEVQEFDPLIDAVVFGDRDVQVTAEKTLTVSLLGNTYEVSAGTQTVPEAVAVFLCCRGLAEIAEGR

priS

DNA primase small subunit PriS

377 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.866 kDa

MSRQESSNKFFIKKILREYYSRKPLEEPLYIHKREIAIHSLEDEAYIRHLSFPSITHLYNFILNEKTPLHLYYSSAYYESPSVNKMELKGWIGSDLMFDLDSDHYPGCDKILSICIEENTIYDGKIKTCPKTESKPVIHPLIKTECIQKAYRDALRIKYILEDELGLKNIKIYFSGNRGFHVKVIDEKIWDLESDERREIASYISLENFDINKLFPVIGKRKKYVIITRNEHGIRKRVLDYVIKNNIVNGNELFIKLPLKLLEETINDLTIPIDIVVTMDISRLSRFGNSINGKSGLITKLIEPLDNYEFDINDFCPWSGNIVVKPLIDISGLQVFDEKIDLKRGVKKILDSKIAVYLTLKGIVKIISDEKLVIKNV

priS

DNA primase small subunit PriS

374 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

41.592 kDa

MNPATTEFVRQRFAEYYRKAMLVSPSSLAQREWGFVLFNPGAAELRMRRHIAFPERTELFDYIRNLVPSHVYYSSAYYEKPDAPTMAEKGWCGADLIFDLDADHIVKGPYDQMLSRVKTETEKLLAMLTEELGIDSKQIELVFSGGRGYHVHVRDLAFRGWGSAERRELVDYICGIGIDPAVLLNGGLVPGWPARFRSALAEYIGWLGTLSEDGAMAHLTSLEGVGKESAAGFLKKRAEILAGLSGEIDPTLLKDRVIKAVVHETEGEFRKRLNEKAALADEPVTTDIKRLIRMPTSIHGGSGMRVQPLELRDLPDFDPLVDAVVFSAREVRVDARFPLAMPMLGSTYQIQKGISTVPEAVGVFLCCRGIAEIA

priS

DNA primase small subunit PriS

373 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.863 kDa

MNETDIKFLESAFKKYYFEQFELIRVPERTSEREFGYQKFNSGMTRHISVKDDKELHLLLMQNVPSDVYCSNAYYSFPNLPMNEKDWKEADLIFDIDAKDLNLSCRGNHTLSICNECHEISNNSEKCSKCNSTKLEKKSLPCKNCIDSSKIEVKKLSEILTNDLSVNKDDIQVYFSGNEGFHIYVYNSQFQQNGSRERSELVDYIMFNGAIPEKFGMKKFKPNRNSFPDFDEAGWKGRFSKYVYGSKSKRSKIVSELLSNGYSSFQKTLDDVSENIGTKIDPNVTMDIHRIFRLPGSINSKSGLTKIHCKDLVKFDAYVDSSFLSDDSVEVLANCPIEFKLKNKKFGPYHNEKVSVPTFAAVYMVCKKLATIA

priS

DNA primase small subunit PriS

372 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

41.153 kDa

MHEKDLLLLAESFKRYYFEHFERIPVPDRAAQREFGYQRFGGGMVRHMRVKGSDELRLLLMQNSPSDVYCSNGIYSFPELPMSDKDWKEADLIFDIDAKDLGLPCRKDHTFRRCSSCGRSHSGDGCPRCGPGAHDQISVLCKDCIGGAKKEVEKLMHILEEDLGVGRDSVVVYFSGNEGFHVHIGGTQFQGLGSRERGELADYVRFVGAVPQAFGMGRNGAARRDFDYDDEGGWKGRLHREFFGPKSRSSVAITAAIKEGHRAFGERLKQISPVLGANIDPHVTTDIHRIFRLPGSLNGKSGLAKIPCINLDKFDPGSDACLIDSDEVQVTADMPMRLKLGGRRFGPYNGEAVSVPRFAAAYMVCKGLASAA

priS

DNA primase small subunit PriS

370 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

43.752 kDa

MISYDKSLNYFSLYYRSNHLIMPDLISKREIGYIPFSGTMIRHLSFRNHREIESFVKRNTPRHLYYSSAYYIKPDEKRMEKKIWEGAELIFDLDADHIPGSDKMTYEEILLEVKKHVSRLLNYLINDFGFDDDSIKLYFSGGRGYHVHVVSDRVYSLDSDARREIGNYIKMEDFTIDNIIRASREKPESGPLKRFNEYISEIYSDENYLKRFYNGDFDRYYKSLDVYKDGKKKIDIMRENNYEKFKIVSKRDLDVLNNILNDFKDKYSAEIDEPVTTDVHRLIRFPGSLHGKTGLAVTPVNINEFDNFDPLISAVPEVFKDKYEHVYLNSDYMITMMNEKFSLNAGENKVPLYLALFLTGMKIGNFIEKK

priS

DNA primase small subunit PriS

363 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.735 kDa

MTDNPADNKVFNEVSSLYKQYFDYAINVRKWLEIPDDLPHREIGYGMLKKVDNRNMSFNTNGEYLAWVLKESPFHLYKSLSYMEYPDVVGGAAKKGLIKREVAFDIDTHKTEKCTHDDSWICEECLGEARNQVLILIEDFLFPDFGLSEKDLKIVFTGNRGYHIYLKPEDTKKIGDTKLLEKIEKWEKNERRYFIEYILGKNLNLRNMGSRWKNILIREFKKNKISTKKFEKTSDWKTEIDTRKDNVRREIYETIGKVKSRLELDEKVMDDDIRLLRTIGSLHGYTGLMVKEITYSSLKSNQFDPLNHGVFSKFHKIMYNVNIKQEIDPLTLKGDTFDHKSTEIPASYLLFLFGHGIDFEILE

priS

DNA primase small subunit PriS

357 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.089 kDa

MNENPAANKIFNEVSSLYKQYFEYAIKVRKWLEIPDDLPHREIGYGMLKKVDNRNISFNTEGEYLTWVLKESPFHLYKSLSYMEYPDLVGGAAKKGLFKREVAFDIDTHKTEKCTHDDSWICEECLGEARNQVLILIEDFLFPDFGLSEKDLKIVFTGNRGYHIYLKPEDPELLKKIEKWGKNERRYFIEYILGKNLNLRNMGSRWKNILISEFKKNKIATKKFEKNSDWKTEIDTRKDTTRRKIYETIDKVKSRLELDEKVMDDDIRLLRTIGSLHGYTGLMVKEITYSSLKSNQFDPLNHGVFSKFHKIMYNVNIKQEIDPLTLKGDTFNHKSTEIPASYLLFLFGHGIDFEILE

priS

DNA primase small subunit PriS

357 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.095 kDa

MNDNPAVNKVFNEISSLYKQYFEYAIKVRKWLEIPDDLSHREIGYGMLKKVDNRNMSFNTDGEYLTWVLKESPFHLYKSLSYMEYPDVVGGAAKKGLFKREVAFDIDTHKTEKCTHDDSWICEECLGEARNQVLILIEDFLFPDFGLSEKDLKIVFTGNRGYHIYLKPENPELLKKIEKWGKNERRYFIEYILGKNLNLRNMGSRWKNILIREFKKNKIATKKFEKTSDWKTEIDTRKDTTRRTIYETIGKVKSRLELDEKVMDDDIRLLRTIGSLHGYTGLMVKEITYSSLKNNQFDPLNHGVFSKFHKIMYKVNIKQEIDPLTLKGDTFDHKSTEIPASYLLFLFGHGIDFEILE

priS

DNA primase small subunit PriS

357 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

42.294 kDa

MNDNPATDKVFKEVSSLYKQYFEYAILVRKWLEIPDDLSHREIGYGMLKKVDNRNMSFNTERDYLAWVLKESPFHLYKSLSYMEYPDIVGGAAKKGLFKREVAFDIDTHKTEKCTHDDSWICEECLGEARNQVLILIEDFLFPDFGLDEKDLKIVFTGNRGYHIYLKPEDPELLKRIEKWGKNERRYFIEYILGKNLNLRNMGSRWKNILVREFNKNKIATKKFEKTSDWKTEIDNRKDTTRRTIYETIDKVKSRLELDEKVMDDDIRLLRTIGSLHGYTGLMVKEITYNSLKNNQFDPLNHGVFSKFHKKMYNVKIKQELDPLTLKGDTFDHNSTEIPASYLLFLFGHGIDFEILE

priS

DNA primase small subunit PriS

350 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

41.802 kDa

MNTFAEVQKLYREYYNFAIKNNILEIPEGIEYREFGYGYLKKVDNRNLSFKNEREYKDWVLKNAPMHFYKSLAYMLYPNKSGGASKKGIFRRELAFDIDVHKTKKCKHEDDWICKHCLEEAKNQAIYLIEEFLIPDFGLNEEDLKIVFSGNRGYHIYIKPRDEKIRDIIESYSKEDRRFLMDYILGKNLNLNSVGSGWRRRLIKAIKERDKRISTKKLENEKNWKKVIENLKSKNKIYNIIEETKNKIELDEKVMDDDIRLLRVINSLHGYTGFIVKPLSGLDELRRFNPLEDAIFKDFENKVYEVNIFDDRKFEIEICGKKYNNKSKKITASALLYLFGHNIKFELLKS

priS

DNA primase small subunit PriS

347 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

40.772 kDa

MLMREVTKEERSEFYSKEWSAKKIPKFIVDTLESREFGFDHNGEGPSDRKNQYSDIRDLEDYIRATSPYAVYSSVAFYENPREMEGWRGAELVFDIDAKDLPLKRCNHEPGTVCPICLEDAKELAKDTLIILREELGFENIHVVYSGRGYHIRILDEWALQLDSKSRERILAFISASEIENVEEFRRFLLEKRGWFVLKHGYPRVFRLRLGYFILRVNVPHLLSIGIRRNIAKKILDHKEEIYEGFVRKAILASFPEGVGIESMAKLFALSTRFSKAYFDGRVTVDIKRILRLPSTLHSKVGLIATYVGTKEREVMKFNPFRHAVPKFRKKEVREAYKLWRESLEYE

priS

DNA primase small subunit PriS

346 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

40.405 kDa

MLLREVTREERKNFYTNEWKVKDIPDFIVKTLELREFGFDHSGEGPSDRKNQYTDIRDLEDYIRATAPYAVYSSVALYEKPQEMEGWLGTELVFDIDAKDLPLRRCEHEPGTVCPICLNDAKEIVRDTVIILREELGFNDIHIIYSGRGYHIRVLDEWALKLDSKSRERILSFVSASEIEDVEEFRKLLLNKRGWFVLNHGYPRAFRLRFGYFILRIKLPHLINAGIRKSIAKSILKSKEEIYEEFVRKAILAAFPQGVGIESLAKLFALSTRFSKSYFDGRVTVDLKRILRLPSTLHSKVGLIAKYVGTNERDVMRFNPFKHAVPKFRKEEVKVEYKKFLESLGT

priS

DNA primase small subunit PriS

346 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

40.297 kDa

MSKLLREVTPEERRLYYSGEWDAKKLPEFIVESIERREFGFDHTGEGPSDRKNAFSDVRDLEDYIRATAPYAAYSSVAFYRNPQEMEGWLGAELVFDIDAKDLPLRRCQNEHPSGQVCPICLEDAKELARDTLIILKEDFGFENIHVVYSGRGYHIRVIDEWALKLDSKARERILSYVSAAEEVTFDDIQKRYIMLSSGYFRVFRLRFGYFIQRINENHLKNIGLKRSTAEKLLDEKTRQDIVEKFVNKGLLAAFPEGVGYRTLLRLFGLSTTFSKAYFDGRVTVDLKRILRLPSTLHSKVGLVATYIGSDEKRLEKFDPFKDAVPEFRKEEVQKAYQEWKELHEG

priS

DNA primase small subunit PriS

346 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

39.973 kDa

MAELFREVTKEERVLYYKAEWNAKKLPRFLVEKLENREFGFDHTGEGPSDRKNVFMDVRDLEDYIKATAPYAIYSSVALYEDPKGMSGWLGAELVFDIDAKDLPLRRCGHIHEHGKVCPICLGDAKELARDTLVILKEDFGFEDVHVVYSGRGYHIRVLDDWAIQLDSKSREKILAYISAAEEVTFEDIQSRKIMLSSGYFRVFRLRFGYFIARANENHLLNIGLRKGQVKKILESRDEIYEGFVRKGLLTAFPQGIGYKTLARLFALSSTFSKAYFDGRVTVDVKRILRVPSSLHSKVGLVATYIGSDERKLEKFNPFRDAVPKFREEEVKEAYEEWLELHGDEL

priS

DNA primase small subunit PriS

345 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own, synthesizing DNA strands up to 3 kB. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability for RNA fragments up to 150 bases. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. Displays gap-filling and strand-displacement activities.

Belongs to the eukaryotic-type primase small subunit family.

40.508 kDa

MLLREVTKEERKEFYSNEWNAKQIPDFILQNLDKREFGFDHTGEGPSDRKNSYTDVRDLEDYIKATAPYAVYSSVAFYEKPQEMEGWLGAELVFDIDAKDLPLRRCNHEPGKVCPICLNDAKEIARDTLIVLKEELGFEDVHVVYSGRGYHIRVMDGWALSLDSKSRERILSFISASEIEDHSEFRKMLLERRGWFVLNHGYPRVFRLRFGYFILRVKVEHLINFGIRKNIAKRILDNKETIYEEFVRKGILAAFPDGVGIESLAKLFALSTRFSKAYFDGRVTVDLKRILRLPSTLHSKVGLIAKYIGNNERDVMRFNPFKHAVPKFRRKEVKEEYKRFLEENF

priS

DNA primase small subunit PriS

342 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

40.121 kDa

MSELFKEMTKEERKIYYLKEWNVKKIPSFITKTLENREFGFDHTGEGPNDRKNVFHHIKDLEDYVKITAPYSIYSSVALYEEPKNMEGWLGAELVFDIDAKDLPLKRCNHETGKVCPICLDDAKELTKDTLLILREDFGFENIHLIYSGRGYHIRVLDDWALGLDSKAREKILSYISSAEEITFEDLQERKILLSSGYYRVFRLRFGYFIKRVSEYHLRNIGLNKRQIEQIIDGRDEIYENFVKKAMISAFSQGVGYKTLLRLFSLSTTFSKAYFDGRVTVDVKRILRVPSSLHSKVGLVATYIGNDEKDLEKFNPFKDAVPKFREKEVKEAYDLWKETMEE

priS

DNA primase small subunit PriS

342 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

38.118 kDa

MVEARGGLDPRRLFKAYYSLSPPVEEPRDIAYREFAFQLFDGDVYVRHIGFDSMEELLSYMAREAPKNAYYSVARYSLPTARSMEEKGWLGSELMFDIDVDSLEGCGEVLGDSCLSRGYKQAVRLVEALYRDFGVPSTLYFTGNRGFHVLADCGWCRRLGREERREIARYFTLEGLRLELIIPRPGRRGVRPAPPSPDDPGLRGWIARAALERGVDLSAVHEAIEDLLDDVRVAIDVKVTQDISRLARIVGSLNGKAGLLVARLGLEGFHPGDWLSPFRGEVEFRASARLEESRILGRTVSLEPGRVYSMPAHIAVLLQLKGYGAVAGGEVVVRAAAGWRPL

priS

DNA primase small subunit PriS

335 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

38.567 kDa

MLTKLFLKKKFEEYYSKNEVELPRKFKNREFAFVPLELLPDFVMHRHISFRSETDFRAYILSNVPAHIYFSSAYYERPAEDKMENKGWLGADLIFDIDADHLPVKAQSFEKALEMAKREIKKLTAVLRADFGIRDMKIYFSGGRGYHVHVHDEEFLSLGSAERREIVDYLRLNSPKIVVEDRFANSNAAKRVLNYLRKKLEEDERLTSKLKIKPADLKKEKLTKKVIRAVEKFDYSALSIYIDAPVTADVKRLIRLPGSLHGKTGLRVTEVEDIESFNPLKDALAFGDEAVVVKVARKLNLSIGDFSGKIYPGRVKLPEYAAVFLICRGDASYDS

priS

DNA primase small subunit PriS

333 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

38.387 kDa

MMRDFVSEEKLKLLFEKYYRSTDIDPPALITKREVGFMTFEGEIIRHMHLSNKFELNNMLRTTVPRHVYSSAAYYKKPDEKKMPEKIWEGADLIFDLDSDHLPGAEKMTYEEMLNSIKEQTKRLVNKFLVSDLGISEKDIRIYFSGSRGYHVHVSSEDVYPLGSDARREITDYVSGNSLSISVIDKALKTGEKRPGGWIKDVISKLYELGINAEKISQKQIERAIDQVKSHNATMVDAPVTYDIHRLIRMPQSLHGKSGMMVKEVDLDKFDDFDPLSDAIPKIFLEGDYDINVHEKTRKLRLLDYKIDLPPGRNRVPQYVAIFLVSSGRADFL

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. Possesses a template-independent 3'-terminal nucleotidyl transferase activity.

Belongs to the eukaryotic-type primase small subunit family.

37.598 kDa

MGTFTLHQGQTNLIKSFFRNYYLNAELELPKDMELREFALQPFGSDTYVRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARNMEEKAWMGSDLLFDIDADHLCKLRSIRFCPVCGNAVVSEKCERDNVETLEYVEMTSECIKRGLEQTRNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGNCALLDSDERKEIAEYVMGIGVPGYPGGSENAPGWVGRKNRGINGVTIDEQVTIDVKRLIRIPNSLHGKSGLIVKRVPNLDDFEFNETLSPFTGYTIFLPYITIETEVLGSIIKLNRGIPIKIKSSIGIYLHLRNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.391 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPAARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGGENAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.377 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPGARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGGENAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.41 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.391 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPAARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGGENAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.41 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

330 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.44 kDa

MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDMYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR

priS

DNA primase small subunit PriS

324 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.939 kDa

MFSKATLKERRQYYREEWSTKDMPDFILKDLKKREFGFDHNGKGPNDRYKVFRGSESLKKFLRYKAPFAAYISVAFYNNPRRREDWQKAEYIFDVDAKDIPIRSCQCDGVCEVCLGQALEIVNSLIDTLQDDLGLNNIHLVYSGRGYHIRILDEEMMTSGSELRSEVLKYVAGAEVPKSNFFNPDISNKSFNFEHFSIPVGYSKIFTDKLKYNIQHLVGNEELDEINPKLMKDIIKYRHHLDNDNWGYFKRDIGPRRYKNLTEAMARVNLSTIDAKVSIDLKRILRLPSSLHSKVSMKCMEVKNRETFDPLQEAVPKFVEERGE

priS

DNA primase small subunit PriS

324 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.84 kDa

MSVELKPASKYERKIFYKEEWNVKDVPDFIRNSLTSREFGFDHYGNGPNDRYKVFVDDLRLKRFIKVKQPFAAYCSVAFYDKPNQRKGWQKSELVFDVDAKDIPIRTCDCAEGEVCEKCLNQAKEIVLMIRDVLSGDFGLTNINLIYSGRGYHVRVLDEDVMDASSELRGDIIQYVTGSKLPDLSNEYGFNDLQPFIIPFGYPKNFTRWSKYTILHLRRSSKLDDVNNQLLRDVLKHRNLLQEDLWGMFRSNIGPIRYKKVMNAISRINMQITDTKVSIDLKRILRLPSTLHSKVSMKSTLIKNIETFDPFDDAVPKFVYERND

priS

DNA primase small subunit PriS

323 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

37.892 kDa

MMPMFEPATPLERKRYYREEWNVRDLPDFIADNLHMREFGFDHNGRGPSDRYRVFRDERSLARFMRVRYPFAAYSSVAFYREPWKRKGWQRSELIFDVDAKDLPVRSCECDGVCPTCLDEARELVLMMVDTLKGDLGLGDIHVIYSGRGYHVRVLDPEVMELGSEVRAEILRYTAGAREPRRKFTDGVSSYEMEHFSIPLGYHRVFTERARHVLLHLRGDEDIEDVTARTVKTAVRNRNLILEDRWGEFRSVIGPRVYPRLVKGISKINMRMLDAKVTIDLKRILRLPTSLHSKVSMICMEVKNPETFDPLKSAVPRFVDERE

priS

DNA primase small subunit PriS

322 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

36.708 kDa

MQISISLQGQSKIIYQIFRSYYENAVLDLPQDIELREFAYQPFNSDTYVRHLTFSSVDELRSFILSNVPLHLYFSAARYQIPSAKEMEQKGWLGSDLLFDLDADDICEINVRRFCSGMEILSETCDGEVREISEITVDCINRVFENALVLKDILIQDFGLKPRIFFSGNRGFHIRVDCYNEWANLDSEDRREIAEYIMSPSPPYESNSESGPGWLGRFARGINGVKIDEQVTVDPKRLVRIPGSLNGKAGLKVIEIVNDKFEYDEYLSPFEGIVAFQSNLSGKFNVLGHEIQLRRGEITKLSAKTGVYLALKGYGVIKAHVR

priS

DNA primase small subunit PriS

322 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

36.925 kDa

MIDLFRRYYRENNIDPPELISKREVGYMTFSGEVIRHLKINNRFELNMLLRDAAPMHVYSSAAYYRKPDERKMPEKEWGGADLIFDLDSDHLPGSEKLSQKEMLIQIRDQTERLVSDFLIADFGIPKSSIKIYFSGNRGYHVHISDDRVYRLGSDARREITDYITGNSLDETVVRRAIDMLGIASGGWPAVVSKELGEASPANQRRESDLRKAIKRARENHSVLIDSPVTYDIHRIIRMPNTLHGKSGLIVKEVEIDHLGEFDPFQECIPDQFRDGEYDVFLPEKIKPVEIGGIESPKMPGKHRVKTFMAVYLVASGRAVFP

priS

DNA primase small subunit PriS

318 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

36.702 kDa

MHQEQNKIIKILFSEYYEKAELDLPNDMELREFAYQPFDSETYVRHLSFSSPQELRQYILQNVPLHLYYSSARYQLPSAKEMDEKGWLGSDLLFDLDADEICEVKVRRFCPQDGYETLASNCNGEPPIEYAEITTECIMKVFEKALLIRDILKEDFGLNARIFFSGNRGFHLRVTCYEDCALLDPDDRKEIAEYFTSPKPPVIYEGNPGWSGRIAKGIEGINIDTQVTIDIRRLVRIPGSLNGKAGLMVVEIKNDKFEYGEWLSPFDGDCIFLPYVSAELTLFNNKYTVKRTYPIKIDTRIGVYLALKGLGKVKAYVR

priS

DNA primase small subunit PriS

312 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

35.868 kDa

MIVEVFFRNFYRNFAKFEIDAVDKREFAFQPFSGGMVRHKSFKSLEDLRKFVVEKTPRHIYHSAAYYERPGEEDMERKGWIGADLIFDIDGDHLDTEACRESKIVSLRCLEDAREEANKLIDVLIQELDLKPTRIVFSGNRGFHIHVSSEEVMKLGSRERRELVNYLKAVGFDPSRFIAKLGRRKVVLYEEEAVGNLLRIKQGVEDARAMKVEIDEVVTQDIHRLIRAPGSLNGKTGLVALPISLKELDKGVEYIVDKAIAFRKGHLKFKFEKPVEGPVLFEKVGGREGDVKVLPAYVAIYLELQEFGKIYD

priS

DNA primase small subunit PriS

312 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

36.064 kDa

MITEVFFRNFYRNYAKFDVVSVERREFAFQPFGGGMVRHKSFNSVDELRRYIVEKTPKHIYHSVAYYERPGEEDMDRKGWLGADLVFDIDGDHLNTEACKGSAVVSLRCLEDAKEETNKLIDILVRELDLRPTRIVFSGNRGFHIHITSEEVLKLGTKERREVVNFIKGVGFDPSRFEVKLGRRRVKLYEEEPVGSLLRVRQAVENPDTLRVEIDEVVTQDIHRLIRLPGSLNGKTGLVAMPLELKDLERGVENIVERAIAFRKGNLKFRFEKPLIGEVLFEKIEARAGDLKILPAHVAIYLELQEFGKIYD

priS

DNA primase small subunit PriS

312 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

36.076 kDa

MIVEVFFRNYYRNYAKLEVDEVEKREFAFQPFVGGMVRHKAFKNLEELKRHLVEKTPRHVYYSTARYERPWEEDMERKGWLGADLVFDIDGDHLDTEACRESKVVSLACLEDAKEEANKLIDVLTEELGLKPTKVVFSGNRGFHVHVVDEEVLALGQKERRELVNYLKAVGFDPSKFHMKVGRRKVVLYEEEAVGNLLRIRRGIEDPEALKVEVDEVVTQDVHRLIRAPGSLNGKTGLVALPLSVRDLEKEVAHIVERAIAFRKGNLRLRFEKPFQGTVLFEKVEAREGDIKTLPAHVAIYLELQEFGKIYD

priS

DNA primase small subunit PriS

312 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

35.981 kDa

MIVEVFFRNFYRNYAKFDIDAVEKREFAFQYFEGGIVRHRAFKTLEELKKFVIEKTPRHIYHSSAYYERPGEEDMERKGWLGADLIFDIDGDHLDTEACRESKLVSIACLNDAKEEANKLIDVLTGELGLKPRRVVFSGNRGFHIHVSEEEVLTLGAKERRELVNYLKAVGFDPSRFVVKKGRKKVVLYEEEVGGNLFRIRQGVEDPRALKIEIDEVVTQDIHRLIRVPGSINGKTGLLALPLSQQDLEKDVEQIVERAIVFKKGNLKLRFNKTFEGAVLFEKINAREGDVKVLPAYLAIYLELQEIGKIYD

priS

DNA primase small subunit PriS

312 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

35.688 kDa

MIVEVFFRNYYRNYAKFDVDAVEKREFAFQPFGGGMVRHKAFKSVEELRRFAVEKTPRHMYHSSAYYERPDEGDMERKGWLGADLIFDIDGDHLDTEACRESKLVSIACLNDAREEANKLLDVLTRELGLKPRRIVFSGNRGFHVHVADEEVLALGARERRELVNYLKAAGFDPTRFAAKLGRRKVLLYEEEVEGNLLRIRQGVEDPRALKVEIDEVVTQDIHRLIRLPGSLNGKTGLAALPLTQQDLEKDAGEIVEKAVAFRKGNLKVRFTKDLRGPVLFDRIDAGEGDVKVLPAYLAIYLELQDFGKIYD

priS

DNA primase small subunit PriS

296 amino acids

Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

Belongs to the eukaryotic-type primase small subunit family.

33.662 kDa

MDVKTLVGEYYASLPSGVLREFVEDPSSREWAYTFLKGRDIVFTRKRRLDEVSGFLELYHSTGKFKNPKSWEGLLGWDLVIDVDAELPEEPEAFLKSLGRLLKDVVIACDELRRALGFPRPDVVNFSGSKGFHVRYFDSTVRRWLRWDLHERRGIKPGEIIQRVGRGVVWLAREGFVAGDRVRALREGLLDDSMYDLKRLIRCVGSMNVKSLLPAVPVWSREGGRWVDFRDEVLGMNDLELGCLVAHRTLTWPGRGGLGVVLSRVLDLDTDADPEDPSDFVEVWGNVMSVLGELKP