pldA

Phospholipase D A

1269 amino acids

Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization.

Belongs to the phospholipase D family.

142.142 kDa

MSNNSKSPPNEQHQQQPHPPDVLVQLTESFQHFFQSLSPQYQSMTSLPSINKDSYTSVGSAPTTNNNSNSNSNSNSSNRSLNNSGSSNSGGGGSNSNKKVNNNNNNNNNNNNNNLQSPTQSQFPYHYQYSSKALHDFEEKRKLLIEQLKSVKINLDTQCDDDPISFIKIRMELTKVKTSLETELKSLDELLHTTSEVEEPNPTPIDSITSLLTMIMPSSISNSVTNNTPSSATPLTLSNNNNYTSSSLATSPTTNSSSSSSSSSSSSSTHYYNSSISSNSLSSNLPPSSIPILNTSNNKNSYPNSIIPQGTPLDNPDPNLPRFPQRDHISVKLYVDCDDYFAASAQAIENATREVFITAWFLSPEVYLIRFPSLDERYRLDNLLKRKAMQGVKIFIILWDETKIATFKGSKRAKDKLEELHTNIKVIKHPPIIPIYWSHHQKTLIIDQEIAFVGGVDFCFGRFDTWCHHLIDVNSTLWKGKDYYNPILGDMGDILVPFEDSVDRKKIPRMPWHDVMAGVNGLAARDVALNFILRWNHHKDDYYPQLYFDTTPLSPVGTSQCQLLRSMDEWSGGGRIERSIHTAYVQAIEDANHYIYIENQNFVSTHAPNVWNQISFEIVKRIKRAIRKKEVFRVFIVIPCQQDGKVEETQIKGLMHWQYSTIIRGENTIMKLLRRDCPDVDLTEYICFLSLRTHAFLEGTFVTEQIYVHSKLMIVDDRTIIVGSANINDRSLIGERDSELAFIIRDEIDTIQTKMNGQDYIASRLVFNFRLRLWKEHLGLLPQINYPPHDQINNDINNIVNLNNNNNSNINNNINNNNNEINNNNNNNNNNNSNEINNNNSDGILNNSNSFHHGSVSDNLPPLNPSSNLNSSNKKLPTTTTAAAAATTTTTTTTTTTTTNGTGTTNKQKTSHHRSNSFQGLVLQSPGSNRSNLSSPQDSPQDSPRLKNLAEEISPPPTEQHQHQSPITDINLILENVDTIIHSNEQLPPPPSSTTPPPPPPPLTTTDSVIIEDYKSDGGNLNIENNNSNNTILTNAATSMNNSTSSLSSTSLPTTTTTTTAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPSQQQQQQQQQLSQQQQLQIKKKRSSISPSTSSNKLLLSGNGSGDSIRVVTDSGSSPRGQPRSMSSLHDHADSSYCQKSNIDLIDPTCSDFYFGVWIATAASNTRIYDTVFPAIPKNSIKTCEQFAQLQKIPVSLADSKLLSEVRGNLVFHPLDFLEGEDLQPSFLFTDDLFQ

pldA

Phospholipase A1

289 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

33.163 kDa

MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF

pldA

Phospholipase A1

289 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

33.163 kDa

MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF

pldA

Phospholipase A1

289 amino acids

Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins.

Belongs to the phospholipase A1 family.

33.163 kDa

MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF

pldA

Phospholipase A1

289 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

32.945 kDa

MRTGPGWLLAAAALPFFACAQEATIDKVHDTPAVRGSIIANMLQEHDNPFTLYPYESNYLLYTYTSDLNKKAIESYNWSDNANKDEVKFQLSLAFPLWRGILGDNSLLGASYTQRSWWQLSNTGESAPFRETNYEPQLFLGFATDYSVGDWTLRDAEFGYNHQSNGRSDPTSRSWNRLYSRLMAQNGNWLVEVKPWYVIGDTSDNKNITKYMGYYQLKIGYQLGEAVLSAKGQYNWNTGYGGAELGVSYPITKHVRFYTQVYSGYGESLIDYDFNQTRVGMGVMLNDLF

pldA

Phospholipase A1

289 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

32.967 kDa

MRAILRGLLPATLLPLAAYAQEATIKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTNTSDLNKEAISTYNWSENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSKESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVIGSTDDNPDITKYMGYYQLKIGYHLGEAVLSAKGQYNWNTGYGGAEVGLSYPVTKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDIF

pldA

Phospholipase A1

289 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

32.967 kDa

MRAILRGLLPATLLPLAAYAQEATIKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTNTSDLNKEAISTYNWSENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSKESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVIGSTDDNPDITKYMGYYQLKIGYHLGEAVLSAKGQYNWNTGYGGAEVGLSYPVTKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDIF

pldA

Phospholipase A1

286 amino acids

Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.

Belongs to the phospholipase A1 family.

32.544 kDa

MRISLACLAALCALPAGVMAQDASVHDKPAVRGSIIANLLQDHDNPFLLYPYESNYLLYTWTSDLNKEAIRSYDWAENARKDEVKFQLSLAFPLWRGILGDNSLLGASYTQKSWWQLSNSKESAPFRETNYEPQLFLGFATDYQFAGWTLRDIEMGYNHDSNGRSDPTSRSWNRLYARLMAQNGNWLVEVKPWYVVGSTDDNPDITKYMGYYRLKVGYQLGEAILSAQGQYNWNTGYGGAELGVSYPITKHVRAYTQIYSGYGESLIDYNFNQTRVGVGLMLNDLF