phnPP

Phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase

262 amino acids

Involved in degradation of methylphosphonate. Catalyzes the hydrolysis of the phosphate ester at carbon-1 of 5-phospho-D-ribose 1,2-cyclic phosphate to form ribose 2,5-bisphosphate. This intermediate is then hydrolyzed to ribose-5-phosphate and inorganic phosphate.

Belongs to the PHP family.

28.613 kDa

MIEDLHVHSTMSDGSDTFEQVLEQAAQRGVERLAFTNHDTTAGLTAARELGERLGVQVVGGIEVSAYDFERGRKVHILGLGVEEGAPALAALCGSTLERRHANSLWQLDRLVEAGYEVDVERALELGRASTCLYKQHLMAALTSEPYPSAAYRTLYRSLFKNGGICDRDIDYVDARDAVRVVVEDGGLAVLAHPGQLDSYDLLPDLVECGLGGIERFHPDHTLADHARCAELAVRYRLVCTGGSDYHGKFGRVPHVGFRVPA