PHC2

Polyhomeotic-like protein 2

858 amino acids

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

90.713 kDa

MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS

Phc2

Polyhomeotic-like protein 2

850 amino acids

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

89.799 kDa

MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGSGGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELCTGSPARPPTPAQVQNLTLRTQQTPAAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQGSPAGAKPSGTDNAPETLKAGDGNCNMEGRPGPGRAVPAVATHPLIAPAYAHLQSHQLLPQPPAKHPQPQFVAQQQPQPPRPAPQVQSQPQLASVSPSLALQSSPEDHALPLGSVTQALPLQCSTTHVHKPGNSQQCHLPTLDTGSQNGHPEGGSHPPQRRFQHTSAVILQVQPASPVTPQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGGLPGPKSPNIQQCPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKPPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS

phc2

Polyhomeotic-like protein 2

827 amino acids

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

88.68 kDa

MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNSSSRQQTVPQISVYGGITDRQTVQVIQQALNRQPSTVAAQYLQQMYAAQQQHLMLQTAALQQQHLSLAAVQQASIVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSGSSVPVCIGQQAVLLGNSSTPTLTASQAQMYLRAQMAQQTNLVQVARSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPPTSGQVQNLALRSQQGALTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAEPSPQGTAAKASPAETSSETTAKNDKTSDLTTSVCPSVTSVAGHPFISTAYTQIQTHQLLQQHKQQFVIQQQPQILQRGQAQLLEAAAIHPHTVQAVAIQSALPAQPQQCPIPLLPKVPVTCQQATIFHSTTVSQQALAQNGQAHILTHTKAPPLQLTAVKCQIHPVQIQQGVASQNVPDKDTPVLLEPQLLSIPIQEPTRTELRQSDKESQVKENTQGSVNVKAGVGSPPAMTSGSGNNAPTVTGSAPQNGESKPPPQAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQHHAYSDLQKHNADSEMEDLSLQELNNQPEPVRTCEFCGNVDFAFNFKRSKRFCSTVCAKRYNVGCTKRMGLFPGKSSPEDTKKPKASDESPKNCSTETRKRNPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFGAPIEHEESFDHSRELTPLLTQHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS

phc2

Polyhomeotic-like protein 2

344 amino acids

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

37.932 kDa

MTSGNGSSPVPTAATGNRTQNGENKPPQAVVKPQILTHFIEGFVIQEGAQPFPSHRSRAVLEVGHSSLLTGAQEKYQQSLLAEKVPQQDNNTTTTTTDSEMEETLVPGFPESKGDGDPPKLKCELCGRVDFEYKFKRSKRFCSMACAKRYNVGCTKRVGLFHPDRSKLQKPTVAKHARRRSRKTPLQTVGADPKKQQAAPVTPMNPGPIPSPSALKLSNSQEDSSRCSDNSSYEEPLSPMSASSSLSRARQEHNVEPPNLHSRDPIAMSQDFLPSDPTKWNVEDVYDFVRSLPGCQEISEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKLYARISMLKDS