phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

636 amino acids

Polymerizes D(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.

Belongs to the PHA/PHB synthase family. Type I PhaC subfamily.

71.936 kDa

MYNKRIKRVLPPEEMVTDSKQESGGQKNGDKTGFDATDLKPYLLKDPETMAMNFARALENLGQAASAWLAPRERGEITETAIDPMTDMVKTLSKISEYWISDPRRTFEAQTQLMSSFFGIWMRSMQRMQGTRGMQGEPLPPEPDTRKDKRFSDEDWQKNPFFDFLRQVYFVTSDWVDKLVSETDGLDEHTKHKAGFYVKQITAALSPSNFIATNPQLYRETIASNGENLVRGMKMLAEDIAAGKGELRLRQTDMTKFAVGRDMALTPGKVIAQNDICQIIQYEASTETVLKRPLLICPPWINKFYILDLNPQKSFIKWCVDQGQTVFVISWVNPDGRHAEKDWAAYAREGIDFALETIEKATGEKEVNAVGYCVGGTLLAATLALHAKEKNKRIKTATLFTTQVDFTHAGDLKVFVDEEQLAALEEHMQAAGYLDGSKMSMAFNMLRASELIWPYFVNSYLKGQEPLPFDLLFWNADSTRMAAANHAFYLRNCYLRNALTQNEMILDGKRISLKDVKIPIYNLATREDHIAPAKSVFLGSRFFGGKVEFVVTGSGHIAGVVNPPDKRKYQFWTGGPAKGEYETWLEQASETPGSWWPHWQAWIETHDGRRVAARKPGGDALNAIEEAPGSYVMERT

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

611 amino acids

Polymerizes D(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.

Belongs to the PHA/PHB synthase family. Type I PhaC subfamily.

68.04 kDa

MTAEKAEGATGFAGFDPKSVEPYIVKDPESLAINMARAAEQLGKAASAWLAPREAGEKTDSFAEPVSDMVKTLSKVSEYWLSDPRRTLEAQTHLLGSFFDMWSRTLQRMAGDAVEDPANLQRNDKRFADEDWVKNPFFDFIRQAYFVTSDWAERMVRDAEGLDDHTRHKAAFYVRQIASALSPTNFITTNPQLYRETVASSGANLVKGMQMLAEDIAAGRGELRLRQTDTSKFAIGENIAITPGKVIAQNDVCQVLQYEASTETVLKRPLLICPPWINKFYVLDLNPEKSFIKWAVDQGQTVFVISWVNPDERHASKDWEAYAREGIGFALDIIEQATGEREVNSIGYCVGGTLLAATLALHAAEGDERIRSATLFTTQVDFTHAGDLKVFVDDDQIRHLEANMSATGYLEGSKMASAFNMLRASELIWPYFVNNYLKGQDPLPFDLLYWNSDSTRMPAANHSFYLRNCYLENRLSKGEMVLAGRRVSLGDVKIPIYNLATKEDHIAPAKSVFLGSSSFGGKVTFVLSGSGHIAGVVNPPARSKYQYWTGGAPKGDIETWMGKAKETAGSWWPHWQGWVERLDKRRVPARKAGGPLNSIEEAPGSYVRVRA

phaC

Poly(3-hydroxyalkanoate) polymerase

605 amino acids

Belongs to the PHA/PHB synthase family.

66.773 kDa

MGTERTNPAAPDFETIARNANQLAEVFRQSAAASLKPFEPAGQGALLPGANLQGASEIDEMTRTLTRVAETWLKDPEKALQAQTKLGQSFAALWASTLTRMQGAVTEPVVQPPPTDKRFAHADWSANPVFDLIKQSYLLLGRWAEEMVETAEGIDEHTRHKAEFYLRQLLSAYSPSNFVMTNPELLRQTLEEGGANLMRGMKMLQEDLEAGGGQLRVRQTDLSAFTFGKDVAVTPGEVIFRNDLMELIQYAPTTETVLKRPLLIVPPWINKFYILDLNPQKSLIGWMVSQGITVFVISWVNPDERHRDKDFESYMREGIETAIDMIGVATGETDVAAAGYCVGGTLLAVTLAYQAATGNRRIKSATFLTTQVDFTHAGDLKVFADEGQIKAIEERMAEHGYLEGARMANAFNMLRPNDLIWSYVVNNYVRGKAPAAFDLLYWNADATRMPAANHSFYLRNCYLNNTLAKGQMVLGNVRLDLKKVKVPVFNLATREDHIAPALSVFEGSAKFGGKVDYVLAGSGHIAGVVAPPGPKAKYGFRTGGPARGRFEDWVAAATEHPGSWWPYWYKWLEEQAPERVPARIPGTGALPSLAPAPGTYVRMKA

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

589 amino acids

Polymerizes (R)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.

Belongs to the PHA/PHB synthase family. Type I PhaC subfamily.

64.317 kDa

MATGKGAAASTQEGKSQPFKVTPGPFDPATWLEWSRQWQGTEGNGHAAASGIPGLDALAGVKIAPAQLGDIQQRYMKDFSALWQAMAEGKAEATGPLHDRRFAGDAWRTNLPYRFAAAFYLLNARALTELADAVEADAKTRQRIRFAISQWVDAMSPANFLATNPEAQRLLIESGGESLRAGVRNMMEDLTRGKISQTDESAFEVGRNVAVTEGAVVFENEYFQLLQYKPLTDKVHARPLLMVPPCINKYYILDLQPESSLVRHVVEQGHTVFLVSWRNPDASMAGSTWDDYIEHAAIRAIEVARDISGQDKINVLGFCVGGTIVSTALAVLAARGEHPAASVTLLTTLLDFADTGILDVFVDEGHVQLREATLGGGAGAPCALLRGLELANTFSFLRPNDLVWNYVVDNYLKGNTPVPFDLLFWNGDATNLPGPWYCWYLRHTYLQNELKVPGKLTVCGVPVDLASIDVPTYIYGSREDHIVPWTAAYASTALLANKLRFVLGASGHIAGVINPPAKNKRSHWTNDALPESPQQWLAGAIEHHGSWWPDWTAWLAGQAGAKRAAPANYGNARYRAIEPAPGRYVKAKA

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

583 amino acids

Polymerizes D(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.

Belongs to the PHA/PHB synthase family. Type I PhaC subfamily.

64.74 kDa

MEAFAQNLAKMVEEGGKAVAAYMRPREEGKPDDMTDDIADALKTIGEVANYWMSDPKRSFEAQSRLMMGYMGVWAGALQKLSGEKAEPIAKADPKDGRFKDPEWESPFFDALKQTYLVTSNWAESMVKEAEGLDPHTKHKAEFLVRQLSNAVAPSNFLMTNPELIRETLSSSGENLVRGMKNLAEDLVEGKGDLKIRQTDMSAFEVGRNLALSPGKVIFETELMQLIQYAPSTPSVKKTPVLIVPPWINKFYILDLTPEKSLIKWMVDQGLTVFVISWVNPDARLADKGFDDYMRDGIFAALDAVEKATGEHQAHTIGYCVGGTLLAVTLAYMAATGDDRVASSTFLTTQIDFTHAGDLKVFVDEAQLSVIERRMKEMGYLEGRKMADAFNMLRSNDLIWPYVVNNYLKGKQPFPFDLLFWNADSTRMPAANHSYYLRNCYLQNNIAKGLAEIAGVKIDMGKVTIPVYSLATREDHIAPPNSAYIGAGLLGGPVRFVLAGSGHIAGVVNPPVKHKYQYWTGGPTGGDYDVWLKGAQEHKGSWWPDWAQWFSALHPDEVPAREPGGSAFNPIEDAPGRYVREKS

phaC

Poly(3-hydroxyalkanoate) polymerase

568 amino acids

Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV).

Belongs to the PHA/PHB synthase family.

63.27 kDa

MQQFVNSLSQPPAPDGAAHPFAGAWAQLMNQTNQLFALQSSLYQQQLNLWSQFLGQAAGQEAAAEAGAKPADRRFASPEWNEHPFYNFLKQSYLQTSKWMMELVDKTQLDEDAKDKLAFATRQYLDAMSPSNFMLTNPDVVKRAIETKGESLVEGMKNMLDDFQKGHISMSDESKFEIGKNLVVTPGQVVFRNELIELIQYTPTTDKVYEKPLLFVPPCINKYYLMDLQPDNSMVRHFVAQGYRVFLISWRSAVAEMKHFTWETYIEKGVFAAAEAVQKITKQPTMNVLGFCVGGVILTTALCVAQAKGLKYFDSATFMTSLIDHAEPGEISFFIDESVVAGREAKMASGGIISGKEIGRTFASLRANDLVWNYVVNNYLLGKTPAPFDLLFWNNDAVDLPLPMHTFLLRQFYMNNALVRPGAITLCGVPIDIAKIDVPVYMFAARDDHIVLWSSAFSGLKYLQGAPSRRFVLGASGHIAGSINPVTKDKRNYWANDTLPLHAEEWLESAESRPGSWWKDWDAWLAPQSGKQVAAPKSLGNKEFPPLLAAPGSYVLAKAMPSVAASLQ

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

492 amino acids

Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV). Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).

Belongs to the PHA/PHB synthase family.

54.765 kDa

MTPVTFALDLQRRQWEQAAELVDRTSAASDRAETVSEVSVGKTPNEVVYKENKLRLLHYESKTETQYDVPILIVYALINRPYILDLQPDRSVVQTLLEQGFDVYLIDWGEPSRLDTHLTLDDYVTRYIDNCVDIVRDRSGQDSINLLGYCMGGTMSVMYAALFPEKVRNLGLMAAGLVFDDTGGVLERWGDEQYYSPKAVTDAFGNVPSEFLDVGFALMDPVENFVTKYVRLFENVENESFVENFSRMEQWLSDGIDVAGETYKQFLEDVYQQNKLAQNELMLDGKQVDLERLEMPILQIVGEYDHLIPPEASKPFNDLVPSEDTEVIEGATGHIGLSVSSRSHGDLWPAVSDWFAERSETGTDETPDSETEETRPDSQAEETDETPDEGLKPQAAASNETVAEEPEPQVVESNETTEEELEPQAVEANETAPEELESIDGIGPTYAERLASVGITSVSGLAAADPSEIAATIDVPVSRVTAWVEQASDRTD

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

475 amino acids

Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV). Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).

Belongs to the PHA/PHB synthase family.

53.121 kDa

MSSNPFNPFEAALNWQRKTLENMTDAAETSQVADERLELMESVDVGQTPSNVVYEENKLELLHYDAEAAGIEVPDEEKEDVPILIVYALINRPYILDLQEERSVVRRLLEAGHDVYLIDWNEPSRLDQHLTLDDYVNRYMDNCVDVVRDRSGQDAINILGYCMGGTMSVMYTALHKEKVNTLGLMAAGLCFDHTGGVLEEWGSEEYYSPQDVVDTFGNVPADMLDIGFALMDPVENYVTKYIRFAENMENEGFVENFGRMEQWLGDGIDVAGEAYVQFLEDVYQDNKLYKNELELDGKHVDLDNIDMPVLQLMGEYDHLIPPEASKPFNDVIASDDTRTIEFSTGHIGLSVSSSTHADLWPEVAEWYSERSTGSEEVDIEVESPEAAEDDAVDQSELTDIDVDATDDVDADATEDDATDEPADVDSVSGIGPTYAERLHDAGIHSVADLAEYDAADLADIAETTESRAQDWLDQL

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

474 amino acids

Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV). Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).

Belongs to the PHA/PHB synthase family.

52.982 kDa

MSSNPFNPFEAALNWQRKTLENMTDAAETSQIADERLELMESVEVGQTPSDVVYEENKLELLHYDAEATGIEVAEEDKEAVPILIVYALINRPYILDLQEERSVVRRLLEAGHDVYLIDWNEPSRLDQHLTLDDYVNRYMDNCVDVVRERSGQDAINILGYCMGGTMSVMYTALHKEKVNTLGLMAAGLCFDHTGGVLEEWGSEEYYSPQDVVDTFGNVPSDMLDIGFALMDPVENYVTKYIRFAENMENEGFVENFGRMEQWLGDGIDVAGEAYVQFLEDVYQDNKLYKNELELNGKHVDLDNIDMPVLQLMGEYDHLIPPEASKPFNDVIASDDTRTIEFSTGHIGLSVSSSTHADLWPEVAEWYSERSTGGEEVDIEVESPEDDTVDQSESTDIEVDATDDVDADATEDDADAADEPADVDSVSGIGPTYAERLHAAGIHSVADLAEYDAAELADIAETTESRAQDWLDQL

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

378 amino acids

When expressed in E.coli with Synechocystis PhaE and C.necator PhaA and PhaB, confers the ability to synthesize up to 13% (w/w) poly(3-hydroxybutyrate) (PHB) depending on the carbon source; all 4 genes are necessary for PHB production (PubMed:9683655). Cell-free in vitro coexpression with PhaE gives a heterodimer able to polymerize 3-hydroxybutyrate-CoA (PubMed:25629766).

Belongs to the PHA/PHB synthase family. Type III PhaC subfamily.

42.961 kDa

MFLLFFIVHWLKIMLPFFAQVGLEENLHETLDFTEKFLSGLENLQGLNEDDIQVGFTPKEAVYQEDKVILYRFQPVVENPLPIPVLIVYALVNRPYMVDLQEGRSLVANLLKLGLDVYLIDWGYPSRGDRWLTLEDYLSGYLNNCVDIICQRSQQEKITLLGVCQGGTFSLCYASLFPDKVKNLVVMVAPVDFEQPGTLLNARGGCTLGAEAVDIDLMVDAMGNIPGDYLNLEFLMLKPLQLGYQKYLDVPDIMGDEAKLLNFLRMEKWIFDSPDQAGETYRQFLKDFYQQNKLIKGEVMIGDRLVDLHNLTMPILNLYAEKDHLVAPASSLALGDYLPENCDYTVQSFPVGHIGMYVSGKVQRDLPPAIAHWLSERQ

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

355 amino acids

Polymerizes D(-)-3-hydroxybutyryl-CoA to create polyhydroxybutyrate (PHB) which consists of thousands of hydroxybutyrate molecules linked end to end (PubMed:7957260). This subunit has catalytic activity that is enhanced 100-fold by PhaE, the non-catalytic subunit (PubMed:9888824).

Belongs to the PHA/PHB synthase family. Type III PhaC subfamily.

39.775 kDa

MFPIDIRPDKLTQEMLDYSRKLGQGMENLLNAEAIDTGVSPKQAVYSEDKLVLYRYDRPEGAPEAQPVPLLIVYALVNRPYMTDIQEDRSTIKGLLATGQDVYLIDWGYPDQADRALTLDDYINGYIDRCVDYLREAHGVDKVNLLGICQGGAFSLMYSALHPDKVRNLVTMVTPVDFKTPDNLLSAWVQNVDIDLAVDTMGNIPGELLNWTFLSLKPFSLTGQKYVNMVDLLDDPDKVKNFLRMEKWIFDSPDQAGETFRQFIKDFYQNNGFLNGGVVLGGQEVDLKDITCPVLNIFALQDHLVPPDASRALKGLTSSPDYTELAFPGGHIGIYVSGKAQKEVTPAIGKWLNER

phaC

Poly(3-hydroxyalkanoate) polymerase subunit PhaC

355 amino acids

Polymerizes D(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.

Belongs to the PHA/PHB synthase family. Type III PhaC subfamily.

39.595 kDa

MRPIDIRPDKLAQEMLDYTSKLGQGMENLLNADAIDTGVSPKEAVYSEDKLVLYRYDTPAGVTPQKTPLLIVYALVNRPYMTDIQEDRSTIKGLLATGQDVYLIDWGYPDQADSALTLDDYINGYIDSCVDYLCETHEVDQVNILGICQGGAFSLMYASLHPDKVKNLVTMVTPVDFKTPGNLLSAWVQNVDIDLAVDTMGNIPGELLNWTFLSLKPFSLTGQKYVNMVDMLDDPDKVKNFLRMEKWIFDSPDQAGETFRQFTKDFYQKNGFINGGVKLGGKEIDLKNVDCPVLNIYALQDHLVPPDASKALNPWSAARTYTELAFPGGHIGIYVSGKAQKEVTPAIGKWLNERS

phaC

Probable K(+)/H(+) antiporter subunit C

115 amino acids

Part of a K(+) efflux system which is required for the adaptation of R.meliloti to alkaline pH as well as for the infection process during symbiotic nodule development.

Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.

12.214 kDa

MELILSAGIGTLTASGVYLLLRPRTYQVIIGLSLLSFAVNLFIFGMGRLRVNAPPILDPGGVGDLARYTDPVPQALVLTAIVIGFAMTALFLVVLLASRGFTGTDHVDGREQRGD