Protein
Ultraviolet N-glycosylase/AP lyase
Organism
Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230)
Function
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. Initiates repair at cis-syn pyrimidine dimers. Proceeds via an imino enzyme:DNA intermediate.
Similarity
Belongs to the Nth/MutY family.
Sequence
METESTGTPTGETRLALVRRARRIDRILAETYPYAVAELDFETPFELLVATVLSAQTTDVRVNAATPALFARFPDAHAMAAATEPELQELVRSTGFYRNKASAILRLSQELVGRHDGEVPARLEDLVALPGVGRKTAFVVLGNAFGQPGITVDTHFGRLARRLGFTDETDPGKGRARRGRPVPPARDWTMLSHRLIFHGRRVCHARRPACGRCPIARWCPSYAAGETDPERARALLAYELKPGREELLELLRAGRTAGAAGPRPRAGGXAPGLPAQPFR