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pah-1

Gene
pah-1
Protein
Phenylalanine-4-hydroxylase
Organism
Caenorhabditis elegans
Length
457 amino acids
Function
Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine (PubMed:18460651, PubMed:10928216). Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan (PubMed:10928216). Plays a role in the biosynthesis of a melanin-like cuticle pigment (PubMed:18460651).
Similarity
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Mass
52.129 kDa
Sequence
MPPAGQDDLDFLKYAMESYVADVNADIGKTTIVFTLREKAGALAETLKLFQAHDVNLSHIESRPSKTHEGCYEVLVEFAEAEDHRKIEGVIEHFQQKAEKKVLVQDWNTKNKQNKDSVPWFPQKINDIDQFANRILSYGAELDADHPGFKDMTYRERRKFFADIAFNFKHGDKIPTITYTDEEIATWRTVYNELTVMYPKNACQEFNYIFPLLQQNCGFGPDRIPQLQDVSDFLKDCTGYTIRPVAGLLSSRDFLAGLAFRVFHSTQYIRHHSAPKYTPEPDICHELLGHVPLFADVEFAQFSQEIGLASLGAPDDVIEKLATLYWFTIEFGICQQDGEKKAYGAGLLSSFGELQYALSDKPEVVDFDPAVCCVTKYPITEYQPKYFLAESFASAKNKLKSWAATINRPFQIRYNAYTQRVEILDKVAALQRLARDIRSDISTLEEALGKVNNLKMK