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p28

Gene
p28
Protein
E3 ubiquitin-protein ligase p28-like
Organism
Variola virus (isolate Human/India/Ind3/1967)
Length
242 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.556 kDa
Sequence
MEFDPTKINISSIDHVTILQYIDEPNDIRLTVCIIQNINNITYYINITKINPHLANQFRAWKKRIAGRDYMTNLSRDTGIQQSNLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIDNNTYTPNTPNNTTTISELDIIKILDKYEDVYKVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin-protein ligase p28-like
Organism
Cowpox virus (strain Brighton Red)
Length
242 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.611 kDa
Sequence
MEFDPTKINISSIDHVTILQYIDEPNDIRLTVCIIQNINNITYYINITKINPHLANQFRTWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNNYTPNTPNNTTTISELDIIKILDKYEEVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin-protein ligase p28-like
Organism
Cowpox virus (strain GRI-90 / Grishak)
Length
242 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.57 kDa
Sequence
MEFDPTKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINPHLANQFRAWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNTPNNTTTISELDIIKILDKYEDVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin-protein ligase p28-like
Organism
Monkeypox virus (strain Zaire-96-I-16)
Length
242 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.64 kDa
Sequence
MEFDPVKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINPHLANRFRAWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNKNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNTPNNTTTISELDIIKILDKYEDMYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGALDNCPICRTRFRKITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin-protein ligase p28
Organism
Ectromelia virus (strain Moscow)
Length
241 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.383 kDa
Sequence
MEFDPAKINTSSIDHVTILQYIDEPNDIRLPVCIIRNINNITYFINITKINPDLANQFRAWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYNPNTPNSTTISELDIIKILDKYEDVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin ligase p28-like
Organism
Vaccinia virus (strain LC16m0)
Length
239 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor (By similarity).
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.185 kDa
Sequence
MEFDPAKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINTHLANQFRAWKKRIAGRDYITNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNNTTTISELDIIKILDKYEDVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHKTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
E3 ubiquitin-protein ligase p28-like
Organism
Vaccinia virus (strain LC16m8)
Length
239 amino acids
Function
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.
Similarity
Belongs to the poxviridae p28 protein family.
Mass
28.185 kDa
Sequence
MEFDPAKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINTHLANQFRAWKKRIAGRDYITNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNNTTTISELDIIKILDKYEDVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHKTRRETGASDNCPICRTRFRNITMSKFYKLVN

Gene
p28
Protein
Truncated p28 protein
Organism
Vaccinia virus (strain Western Reserve)
Length
184 amino acids
Mass
21.604 kDa
Sequence
MEFDPAKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINTHLANQFRAWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNTPNNTTTISELDIIKILDKYEDVYRVSKEKECGICYEVVYSKR