Protein
OTU domain-containing protein 5-A
Function
Deubiquitinating enzyme that may function as negative regulator of the innate immune system. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).
Similarity
Belongs to the peptidase C85 family.
Sequence
MTILPKKKPNSSVGVSDHPDDPDRRTGSDPHQHQHQHSHGVRPGARPRASPPPWSYQAAPPASREDRRTESSSRPQQASPPPVGAGSSGGPGDATGMACVSGNRAELSGGVGCGGGMGGCCSGPGLSKRRRQATCSGGVAGGGTGPGAAGGGGGGGGGGGVGGPSPEQEEGAGYNSEDEYENASRLQSEDPATVEQQEHWFEKALQEKKGFVIKKMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQSGTEPINTFHGIHQNNDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPAFKPGFADQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQPRKASATCSSATAAASSGLEEWNARSPRQRSSAPSPEIPDPAHSDTAAKPPSPAGALALSKPPSPCAPGPSNQACVGPDRPTSSSLVSLYPALGYRAIMQEMSPTAFGLTDWEDDEILASVLAVSQQEYLDSMKKNAMHREPSPDSS