Protein
Ubiquitin thioesterase otubain-like
Organism
Caenorhabditis briggsae
Function
Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin (By similarity).
Similarity
Belongs to the peptidase C65 family.
Sequence
MVNDTSENQPTTAGIVTTTEDELILQDQQMKRIEDEQKASPLVGEKMPCATLVSLYDQETAPAFFEKANELAKVYSHIRFIRGDGNCFIRAIQVGLVEILLNDKERLVKFIASCKEWTERLVKLGFPDWTCTDFCEFFIEFIEKVRDGIHQKEDVFRIFNDDNTANYLLMFFRLITSGYLKEHAAEYEPFLDEGMSLAQYCETEIEAMWKESDHLGIIALVRALNIRIRIEYMDRNAAPNGGTHHNLPDGHDNATFTPDITLLYRPGHYDLIYKAPAETSKPALPPVA