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nuf2

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
488 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
56.914 kDa
Sequence
MSRPSSIYRPGNSSLTSRRIHHVIPQDSFPLLDFKEISICLQSCDFIANEELVSRPTSQYIKTLLEQLLDSFMGLSADNINGMVRNVNKNDLSMTKTQDAQMEEEPENGGSQIEDDDDITSSVRLILLHRGAYEFFSICGVNDFTLMDIMRPEPQRIRRILSAVVNYARFREENSVECEKLVSISEGNLEQLKVVQNENSRLSNKINDLKYKIEANETDEGNKKATLKQITTYNSKLENELKKLKKNQEILTLEHSKYKDEKRRLIEKLEDHNYLIMESNKELDKLKSYLLSNPEILTKIIEDLKTNLSEYQTNLADLESKNKNMTISIESFQLVEQELKNLFRILEEVLNDLTKEETSLDKLNKYQEFKEQQNLTLNDLNRQIQQVTRQLNNTEEKIKRLRHQSSERSEASKQKLISLKDGYDTLVKERKVKEQELNKKKDFISELETKMNGERSNFQIELRNAELAVAKLNSHVKLYLTEMNKKVD

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
485 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
56.646 kDa
Sequence
MSRQSFYADPSSAGRQMKYRKDLFPLLDTREITACLLECEFNVTQELIVKPTADFVTNLFEQFLDTFMGIPLGTIRKKARKMSRINPLESDQANGKPQQSPEEDFNDNQENDKTKDTFSALQLLILHRYLAIFFSTCGINDFVLTDIARPDGYRIRRILSAVINFIRFREDQSPKFDHLANECEATADKVSEVQAENSATMQKINAIKEKLEMDSENDESNRKNLQYINSYNRKLETKLRELKVMQERLTKEHDDYKQEKALLAKKLYDINFLYNETQEQVANLTKYAETDLSILVKITEDLSNDLSSMQTNYKNLEKSYQNMGITIDSIQVNEINLKDLLKLAEDITRNVEKRQIEGKILKDNQDNLDELTRKQMELEGQILIVQNQLNKSNKKYQDLIVQADKKESAVKLKLEETKQEFNDILSEKEKHNEEHKRIMDQIVKIQQETTAIQDAFVKESKEVELKLINLMSIIKRYMSDLRNNI

Gene
NUF2
Protein
Kinetochore protein Nuf2
Organism
Gallus gallus
Length
469 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12829748). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (By similarity). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (By similarity).
Similarity
Belongs to the NUF2 family.
Mass
55.127 kDa
Sequence
MEALTFPRYSPDDIVAYLRSHVLVGAEARNLTKADLFATLKPEVLHMIFIRILQKVYGIRLEHFYMMPVNVDIVYPQIFEGFLPVCNLYIHMERFLPVCRVNDFQMSDVINPKAKRTARFLSGILNFVHFRECRREAYLELQLNYKSAMEKHQQLETANQELEMKLEKLNTVPVEQQAEFKQLSDDIQELEQLLSHDYRRKTAALQEVISQKKSDITERTRKLNELKVTMATLKEEQEQLKSKIVESPEELKNYKELMKETVKKLKKSKQEVIEKYEGYRDLVEVLPSCQLEVQLYQKKMERQAANVERLASVLSEVRNLEDQLESAQIELKKGKTDEMSLKRLVTAKHERLSTAEIRIKKKREDVEQYKHTVFEYFNRVQEKRGVVYDKVTAIQKEIQQMRFKIQQLNESAEEEEMKAKEIYQNLKAGLEKRHDSLIKTAKNYAASREDKIAELQKGLLRVQSPGSSS

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
467 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.35 kDa
Sequence
MSQQNRRVQQNTAAFPLLTAHDILECLAALDIPAQMEDLTKPTAQSTQSIYGSLLEVLMGASINSIEGPKQALLGMMEYKVLSFRSMKRTQINLSRQEMYSDTLQFMMFFKHCRRLALLCGIPDFAISDLARPDANRLRKVLSGIMNFAKFRDERMQTQARFQENLQKHQKKAVDLRRKTEELETQFQEITARNAAERPQSEQAQKRNELLKSELLELNSQRLKEVQEYEELKKERQTLLEQVNHNNRIVTQLELQIGSAKSRLVQSPDRIKRHISEMSFAIQSEKAKLASFQQKARELTNRLEVIGALEVDLRGLIDLEHSIQDQRAKTEEAKRSKSALEARLEGRQIESQGLAAKLEQLQRQLQNASHKLARQEETRKGMRERGARRIDELKAEYKVRARERGEWQKQRDDLLAEQKELESEMAAFVTKHENEINEFLHAYWTMRRQAEDYMNTMTVKLGLQVQL

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
467 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.295 kDa
Sequence
MSQQNRRVQQNTAAFPLLTAHDILECLAALDIPAQMEDLTKPTAQSTQSIYGSLLEVLMGASINSIEGPKQALLGMMEYKVLSFRSMKRTQINLSRQEMYSDTLQFMMFFKHCRRLALLCGIPDFAISDLARPDANRLRKVLSGIMNFAKFRDERMQTQARFQENLQKHQKKAVDLRRKTEELETQFQEITARNAAERPQSEQAQKRNELLKSELLELNSQRLKEVQEYEELKKERQTLLEQVNHNNRIVTQLELQIGSAKSRLVQSPDRIKRHISEMSFAIQSEKAKLASFQQKARELTNRLEVIGALEVDLRGLIDLEHSIQDQRAKTEEAKRSKSALEARLEGRQIESQGLAAKLEQLQRQLQNASHKLARQEETRKGMRERGARRIDELKAEYKVRARERGEWQKQRDDLLAEQKELESEMAAFVTKHENEINEFLHAYWTMRRQAEDYMNTMTVKLGLQTAI

Gene
NUF2
Protein
Kinetochore protein Nuf2
Organism
Homo sapiens
Length
464 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
Similarity
Belongs to the NUF2 family.
Mass
54.304 kDa
Sequence
METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST

Gene
Nuf2
Protein
Kinetochore protein Nuf2
Organism
Rattus norvegicus
Length
464 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Similarity
Belongs to the NUF2 family.
Mass
54.556 kDa
Sequence
METLSFPRYNIAEIVVHIRNKLLTGADGKNLSKSDFLPNPKPEVLYMIYMRALQLVYGVRLEHFYMMPVNIEVMYPHIMEGFLPVSNLFFHLDSFMPICRVNDFEIADILYPKANRTSRFLSGIINFIHFRETCLEKYEEFLLQNKSSVDKIQQLSNAHQEALMKLEKLNSVPVEEQEEFKQLKDDIQELQHLLNQDFRQKTTLLQERYTKMKSDFSEKTKHVNELKLSVVSLKEVQDSLKSKIVDSPEKLKNYKEKMKDTVQKLRSAREEVMEKYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSILKESLNLEGQIDSDSSELKKLKTEENSLIRLMTLKKERLATMQFKINKKQEDVKQYKRTMIEDCNKVQEKRDAVCEQVTAINQDIHKIKSGIQQLRDAEKREKLKSQEILVDLKSALEKYHEGIEKTTEECCTRIGGKTAELKRRMFKMPP

Gene
nuf2
Protein
Probable kinetochore protein nuf2
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
463 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.522 kDa
Sequence
MAYNHRMSQQFRGSQQHHGRGRKKEDENDALMRLPDKEIAGCINDIGIPFTAADLIKPNPQQIQMVFEWFAELLMNITHEAVEPAMRAAADDVGGDFPDIVPTDTRNLMGFFVSLRKLMMECGVNDFTFTDLTKPTHDRLVKIFSYLINFVRFRESQTPVIDEHFNKSEKTKARIDTLYAENQEMEQRLEEMRRNLRANEAQVKEKVRRNDELKARLLELRRNQERVAETLERVKADKTRRQTQLEEKTEKVVRTRQEVEKLRPYAMESPVSLQASLTELSENLLREKAQIDAMEKRARALQTSSDTFTVVSNDVQACVKLLEDISVELQKEEDEESRASRNKEAISERGNSVREVEQTEKLLQRQLARWNERIETLRKNAQEKAEAAQARMEELREVQKQLREERAEKQRDMERRRIRIEQTEKKMVDLKENIESEIQSAHDEYLRLESHIKLYITEMEKCI

Gene
nuf2
Protein
Probable kinetochore protein nuf2
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
463 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.529 kDa
Sequence
MAYNHRISQQFHSSQQHGRGSRKKEDENDALMRLPDKEIAGCINDIGIPFTAADLIKPNPQQVQMVLEWFAELLMNTTRETVEPAMRAAADDICGDFPDIVPTDTRNLMGFFVNMRRLMAECGVNDFTFTDLTKPTHDRLVKIFSYLINFVRFRESQTAVIDEHFNKTEKTKQRIETLYTENQEMEQRLEEMRRVLKANEAEVKEKVRRNDELKSRLRELGRTQEKVAETLERVKAEKARQQNLLKEKMERTVRTRQEVEKLRPYVMESPASLQSSLTELSESLLREKNQIDAMEKRARALQTSSDTFTVVSNDVQACIKLLEDIAVELQKEEDEESRASRNKEAISERGNNVREVEQTEKLLQRQLARWNERIEALRNTAHEKAQVAQKRMEELREVQIKLREERTEKQRDMERRRIRIEQTEKKMADLKESIETEIQSAHDEYLKLESHIKLYITEMEKSL

Gene
Nuf2
Protein
Kinetochore protein Nuf2
Organism
Mus musculus
Length
463 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Similarity
Belongs to the NUF2 family.
Mass
54.594 kDa
Sequence
METLSFPRYNVAELVVHIRNKLLTGADGKNLSKSDFLPNPKSDVLYMIYMKALQLVYGVRLEHFYMMPMNIEVTYPHLMEGFLPVRSLFFYMDSFMPICRVNDFEIVDILNPRTNRTSRFLSGIINFIHFRETCLEKCEEFLLQNKSSMVRMQQLSNVHQEALMKLEKLNTVPAEEREEFKQFMDDIQELQHLLNEEFRQKTTLLQEEYAKMKSDISEKTKHLNEQKLSLVSLKEVEDNLKSKIVDSPEKLKNYKDKMKGTVQKLRSAREKVMEQYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSLLKESLNLEDQIESDSSELKKLKTEENSLIRMTTVKKEKLATARFKINKKQEDVKHYKQAMIEDCNKVQEKRDAVCEQVTTVNQEIHKIKSAIQQLRDTKKREILKSQEIFVNLKSALEKYHEGIEKVAEERSAKLEEKTAELKKRMVRMV

Gene
nuf2
Protein
Probable kinetochore protein nuf2
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
463 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.724 kDa
Sequence
MAYNHRMSQQFHGTQQHHNRGRKKEDENDALMRLPDKEIAGCINDIGIPFTAADLIKPNPQQIQMVFEWFAELLMNTTKETVEPAMRAAAEDICGDYPDIVPLETRNLMGFFISLRRLMMECGVNDFTFTDLTKPTHDRLVKIFSYLINFVRFRESQTQVIDEHFNKTEKTKARIDTLFMENQEMEQRLEEMRRSLKANEAQVKEKVRRNDELKARLLELRRNQERIAETLERVKADKARRQAQLEEKTERSVRTRQEVEKLRPYAMQSPVSLQSALTELSENLLREKAQIDAMEKRARALQTSSDTFTVVGNDVQACIKLLEDISVELQKEEEEESRASRNKEAISERGNNVREVEQTEKLLQRQLARWNERIEALRKNAQEKAEVAQARMDELRDVQKKLREERAEKQRDMERRRIRIEQTEKKMADLKENIENEIQSAHEEYLKLESHIKLYITEMEKCL

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
462 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.047 kDa
Sequence
MAYNPRMSIIPTSQQNSRTRKKEEEADAFMRLPDREIVGCITDIGITFTVADLQKPNAAHVQQIFEWFAELLLNATRETVEPAMRAAAEDIAGEYADIIPSDTRNLMGFYVSLRRLLFECGITDFSFNDLYKPTYDRLVKIFSYLINFVRFRESQTAVIDQHYNKAESTKTRIETLYGENQENEGRLEDMKRNRKAMEAQVQQKTMRNEELKKRLLELRRNQERVAARLEEAKQKKGELTTALEQKTHEKVTLKQESTKLRPYVLQSASDLQENLAELRDILNNDKSHIDALDRRARALQTSTDSFSVVSTDVASCIKILDEIASELAKEEEELARNAKQRDALSERSNNAREVERTETMLKRQLSKWMERTEKLREQSNHKAHEAKEKMHELRAIHRQLTEEHTEKGKEMEVRRVRIEQTEKKMLDLKENIENEVHSAHEEYRKMEAHIKLYIAEMEQAIA

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
460 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
54.195 kDa
Sequence
MATPTQDIFPLLDLEELVICLQSCDFAMATEEHIARPTSQYVITLYKQIIENFMGISPEQVLAEQLSSRQNTEGNDESTSVDMFDGPYRETLQMLTLNKICYKFFENVGINDFNIVDLYKPEAYRTRRLLSAVVNYARFREERMFDCNQFIIQMEEMLDELKSKFDDFNYLKAQLTAIEDDDEKTPGELEDLLQKNKVLETNLKKLTILQEKLSIDYNNYKMKKQELLRELEKNSFTLIELESKKERLMNYNDDDQDLQNSLNNSIDRLTEEKKKQIGYVSKLEGNVSNLKVTVDTLEKAIEHIYDILRLLSTDLQESHRAELNIEGIKGPLTEKRTRLKNLLESNVIYKYDVLKEQLNVAETEYQRINEEHYRETLENKKLIQELEGKYNNIIHNKMQEAEVYIENEITEKKIKILQSELNDIQIQFNNEIDNIELHYSTLVGHINNYMKKLITALNNH

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
455 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
53.091 kDa
Sequence
MSSDNFPLLDIPELVTCLQECDFSLATIQNVERPSSQFVITLYKQIIDTFMGVSPDSLLEDSRNFVENGDTSEQEVYDASLVYHDTLKILALNKICYKFFLDIGVSDFNVMDLYKPDPHRTRRFLSAVANYARFREEAMLELDGDQHPDGVRYLEQTDKLLKELRLKFDANNLLHSRVQKYKEFQKSDDLEALESDNKNMESELRHLNQVQETLTVDYERYKAEKQRHLSELETLGYELIELESERDKLRKYSQTDAEVLRKGVRELSLLLEQQQVQLEKLEQKQKNLQISFETFQASTQELYEVLQIVSTDLQDSHLKESTLLDAKHKLMQNHKNLNNLLSAGIMAKITLLQEQLDSQKRKLAELELNTQAKESENSATLKRLRKQHTDDVLPEVRNIEQRYKTKVADTITNYESQMRNIKVDFDNEVALIENECSLLFNHIKNYMTTIGEKLG

Gene
nuf2
Protein
Kinetochore protein Nuf2
Organism
Danio rerio
Length
454 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
53.632 kDa
Sequence
MSENTFPVYKVDVIVQFYRTEVLTGQESKHFTKNDLTPTPKPESVQRLYMRILQLLFRFRPECHYTVPLSENIQYPMLYESFAPIMSVYMRMCQFLPVCRVYDFSLSDLLNPKTKRTITILSAIQNFLHFRKQRLEITAAHQQSFRADMDRLQAYTREIKEAEKKIEKLTTIPPEQQAEAKELASALAELSTNTQHEYQDVSAINEKVAQFKTEIAELSQKLTQRKVEVATLKDEISKLKSQIVESPEELKNEMERMRETAKNIKMSKELADERLVELQMLVQCASQVEAEIQILLKQLQDLQSSMSKTKQRKEEVQSLEVMNESLQKELKSLSSEEAQLKRALTMKLDKESKQQIRRQKKKEVKDQQVKNIYGQYDKMHQKRQEIVKKIEECNRETKQFKEKMQALRENCNQRTQKAQEIYERLLTTLEQYHKRIEKILVETNADALKMKSHF

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
452 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
52.702 kDa
Sequence
MSHMAYTPKKQVRTRNTHAAFPTLPIDEIVQCLPGLDCMVTEEELLRPTSKFVQSMYAQIATSLLGINRESMAPALAACAAGTEHPETQEDARMLFALQKPLYDLFVASGVTDYNISDILKPSPERLRVQLSAIINYARFREIREKWYEKMSEELNEEEEARTMRLKNQEEKLRRKVELIALIGDTPDQDLVEQHRINDSRKSELKRLHDQNLQLNDERERNKAELRVVVNRLRHKHQLMESLQEEVARLNSYVVDNPKNLQEEVVELSKRVKERETVRRMLGERVQKLDLSVDSFKDFQVDVSSCLSAFQKLSDEQEAHSKAVRKITTQKELLEHVGINSRQAEGRRDVLQQEIEAAESKIARIQQDMSESDRQTSRRMEELRRQIGTLDAERALVVQQNNTAQKRLAELENDMATERDRYEAQLKMAREEAEKLQTQFREYFVEVGRRLN

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
451 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
52.887 kDa
Sequence
MSKDVFPLLELSELVTCLQSCDFSLAVEENISKPSSQYVITLYKQIIDTFMGVSPDTLLSNEALFDNSGSNDIQQNPAYTETVKVLALNKICFKFFQDIGVSDFNMMDLYKPDSLRTRRLLSAVVNYARFREERMFDCDKFMSKTEFLLNQLRSKFDDYNYLQQQINKHRNEIELREGETFETLQQQNKHLDQQISRLKGLQETLNIDYNAYKSRKQSLLHDLEKFGFELIELEFERNKLEKHSKTDFNELNLNIEKLSTLLATQQTNLNNLEQKHRKLRISMNTFQTLTHELYDVLQLISTDLQESHLREANLIDMREQLLQTDQKLNNILSSGVMVKMKILQSQLDNQKKKLHQLEGETKAKQIENSETLQLLQRQYTDEVVPDLRAAEEQVENDLANGTIKNYDYEISQLKQAFQTEIDAIDLEYSLLSSHINRYMEEMLRVMVEVTS

Gene
NUF2
Protein
Kinetochore protein NUF2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
451 amino acids
Function
Acts as component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
52.973 kDa
Sequence
MSRNQDVFPILDLQELVICLQSCDFALATQENISRPTSDYMVTLYKQIIENFMGISVESLLNSSNQETGDGHLQEENENIYLDTLNVLVLNKICFKFFENIGVQDFNMTDLYKPEAQRTQRLLSAVVNYARFREERMFDCNSFILQMESLLGQLRSKFDDYNLIQQQLKQYEDVDGDNIPDEQELQKLEEQNKELEIQLKKLTKIQETLSIDYNDYKISKQSIFKDLEALSFQIVELESNRDKLIKISNTDMEELSEGIKELNDLLIQRKKTLDDLTAQQKNLQDTVTTFETIISELYDVLRIISSEVQESNRTETELVGLKQNLINNKLKLMNVLETGIMYKLEILQEQLDLQLKNLEKLSQDTKEESRLNDTKLMDLQIKYENEIKPKIDKTDIFIQEELISGKINKLNDEIKQLQKDFEVEVKEIEIEYSLLSGHINKYMNEMLEYMQ

Gene
nuf2
Protein
Kinetochore protein nuf2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
441 amino acids
Function
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
51.911 kDa
Sequence
MARKHTFPSLKRAEILECIDGLGIPFTAKELDQPTSKAVIPLYEEFLDLFMGLTRQNLEEKVNSLQDSVENFEIIHESLRFTVFYQILSQFMQNICFHDFTIQDLLKPDRNRLQLILSAVINFAKLREERLQQFDDDIQKRESLLETYTLLDAQRKDLEEKVLLSQDRKLESEAIIKQNEERNEEMFQSLIEDKRLCSQVRTEYDRIRMEASELKIRYHNVDSLMASTLEEIEKLQSSIVHSPEKLKGKIADTSLRIQNDRSQQVELDKKSKILHTKLNSLQLIEGDLNACLKVLEECLVELDKLEHATVLLSTNQELCDQIEINKKKLEFRKEQLLKQLSNAQEKLEHEQHSRNQKLEAAKQRMDNIREEYKVITQERNKKIQETEKKNAMIEMTEQKIAGMREELESQISSITMEFEKLKSHVELYIAELLRNLRSSNS

Gene
NUF2
Protein
Kinetochore protein NUF2 homolog
Organism
Arabidopsis thaliana
Length
440 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division.
Similarity
Belongs to the NUF2 family.
Mass
50.532 kDa
Sequence
MSAYEYPRLSRSDIITALKDAQIASVTETDLKTPTSDFVSELYTRILIYLDALDEEEKGQVDFEALEQLENPDHHATSMQAMKLYCKVKDMLEMLDCPLPISFKDLLRPESSRTEFFISALLNYGLYKDSKMDLIRPKAEELGLLDEQRKQCEAKVAQLNAEIGEFDEAVERDLPFVQELEANIEQLNKKILELNNQQMSLRATFQKMREKSTQMDNEISKAEFDLVETVQENANLRSQIVQSPDKLQGALEEKKLVLGETKKAEQSAMVTFQEKAAILEVFEKALKKILKSSSQLQLINEQVTNAKTVEKEFKALKDKLSEDGVAYKSLEAKVVERERIVEQLNESLKQLEKEKAVMFDDWTKQLNELKVEVESRRRELETRQTNVESVVAMVDDNTAKTNQVRQSGEAKVKKLAAKYEEIVKQFHEYTVSFDAFLPSL

Gene
NUF2
Protein
Probable kinetochore protein NUF2
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
439 amino acids
Function
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Similarity
Belongs to the NUF2 family.
Mass
50.906 kDa
Sequence
MQKRNVYAVPDLPVKEIMQYFSEMEINIKASDILKPTPQSTQRIYEVLLEVYCGVKTSDLLPRINSGESIEAFEESLSCILLQKRMSGFLKRIGIDNFGLRDLVPDSRRLIGILSVVVNFSMFRDNKRHVYERVCQMNDEKLLLKNEIDEKVHNAKKELERCERDARKSIEEAKGVEEEISLLESELKDFYRHQRALVQETERSKTERNEYSDKLSSLKLMVLNLNQEITCLKTQIVSDPTKLMELLDEMRCLIAKESEIMKGLEVKRVGLKEKIEFMQVLKEDTMKAITLAISNREADKTIDKTNREISELEVQMKNLDSGINALKIRLNHVSRQISHIESKIFNLQDNDKRCSEEISAKLEKLKSNYGVVSDERNSIRGKIEENVRLTKSIEYELVKRRNEHANDITAIQSALCRLKDDVFNYFAEAKGIIDKTMSD