nsaD

2-hydroxychromene-2-carboxylate isomerase

195 amino acids

Involved in the naphthalene and naphthalenesulfonate catabolic pathway. Catalyzes the reversible glutathione-dependent isomerization of 2-hydroxychromene-2-carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). It can also use 2-hydroxybenzo[g]chromene-2-carboxylate as substrate.

Belongs to the GST superfamily. NadH family.

22.064 kDa

MTKTIDFYFDFISPFSYLAQVKLPDLARRTGCVIEYRPIDIPEAKIAAGNYGPSNREVVPKIKVMMADLERWAAKYEVPLTFPASFACSDWNCAALYARGQDQAEAFVTAAYHRIWGIGIDPRDQNELRGCAEDVGLDADALCEFVRSPAGQGEYRKARTQAYQRGVFGAPMMFVDDQIFWGNDRLDFLESYLLD