About Products Protein Database Contact

nhp-1

Gene
nhp-1
Protein
Non-histone chromosomal protein 6
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
103 amino acids
Function
DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
Similarity
Belongs to the NHP6 family.
Mass
11.609 kDa
Sequence
MPKAAAKSKTTGKVEKRRAKKDPNAPKRGLSAYMFFANEQRENVREENPGVSFGQVGKILGERWKALSDKQRAPYEAKAAADKKRYEDEKQAYNAEADEEESS