nhaS2

Na(+)/H(+) antiporter NhaS2

540 amino acids

Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios. May be part of a sodium cycle that permits re-entry of sodium into the cell.

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

58.117 kDa

MIKLPVLLADINIQSLPTEPELILNNLAITTLVENLIILLLVATLVALVARWLKIPYVIGLVLAGLAIPRGLSVGLNPELILNFFLPILIFEAAINTDISRLRSTIKPITVLAGPGVVISAAITAVLLKIGLGLAWVTAAGVSVILTITDTVSVIAAFRSVPVPRRLATIVEGESMLNDGVAMVLLSVITTIHIQGGFSAGEGIRQIFVAFVGGGLVGLGLGYLCVGLFRQLNDDLSDILLTVSVSLGTFQIGQMLGVSSAIAVVVAGLVIGNLALKQTSASIKVTLLSFWEYAGFGVNTLIFLLVGIEVYPSILLSTIPAALIAIVAYQIGRVFSIYPLLYLLSFFDRPLPLRWQHVLIAGNVKGSLSMALALALPLTLPGRDQVVTLVFSTVMVSLIGQGLSLPWVVKKLQLSKPSPLAQKIAMLQLNLVTAKAAQGELKYLLEAGSLPKFLYEELFADYQARIANSEQELREFYNQRNLIFSEGEVEKKYIDGLYRRLYIAEKSAINDALAKGILADDISDEYLQVLNEKLLALQDD