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nde1

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
666 amino acids
Function
Required for nuclear migration.
Similarity
Belongs to the nudE family.
Mass
72.16 kDa
Sequence
MVDDEDDITFDSPEEEIAHYREKYRQALDMLTDTRAELEEFQQSSKELEDEMEQELAANDKQQADLREKIKRLDAEKEEWRTKHIALQKMHSSTTSAMQREMDNLRSERDKTLVALRDLEMGNDELERNERVAISSLLDLESKYNRAIEEKTLLEQDLAQKDELETETQRLKDELREANEEISILKDQLARAIATPPSSVSTSSPIHDAACDLSRIHLSDDINASPLPPPVPSKNKSITPEGHSPRRGLSRSGTMSSIPVASPSTKRFSQQIPHSPSFSTLSRSTTSRNLAAAAGTPGSPALARSRSGIPQASPARGIVLASHQQTKSRGFKLLHDLQARLKATDDKLGGAKVPRRNVSNPASVFGVGKRVTSTTSTTSSTTTAPAPHARVTALAKDHNTTPTAQSQQFPGSGIMSPGWVLVGEGEGEDTPTGPWSMTLPAEPNSPLDPTFRSSSTTSNRSLPSRPGIPSPLASGSARSTTSGTAQRQAGQRPSSRLGLKASRRDSEARPLSPSMIPVPSFSSRPMSPDVYQPLRSATPTSGFSSFSASASTSNPPRPNSRTGKRNPIGRGPPPLSSSTRLHHQRSRQSLSGAGPTPTTGADKVERAKRGPRRSSLSNMDKPSLMSASPGSRTPSGRPTSVHVFRETPPPVPRIPSAILKESKVKK

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
666 amino acids
Function
Required for nuclear migration.
Similarity
Belongs to the nudE family.
Mass
72.15 kDa
Sequence
MVDDEDDITFDSPEEEIAHYREKYRQALDMLTDTRAELEEFQQSSKELEDEMEQELAANDKQQADLREKIKRLDAEKEEWRTKHIALQKMHSSTTSAMQREMDNLRSERDKTLVALRDLEMGNDELERNERVAISSLLDLESKYNRAIEEKTLLEQDLAQKDELETETQRLKDELREANEEISILKDQLARAIATPPSSVSTSSPIHDAACDLSRIHLSDDINASPLPPPVPSKNKSITPEGHSPRRGLSRSGTMSSIPVASPSTKRFSQQIPHSPSFSTLSRSTTSRNLAAAAGTPGSPALARSRSGIPQASPARGIVLASHQQTKSRGFKLLHDLQARLKATDDKLGGAKVPRRNVSNPASVFGVGKRVTSTTSTTSSTTTAPAPHARVTALAKDHNTTPTAQSQQFPGSGIMSPGWVLVGEGEGEDTPTGPWSMTLPAEPNSPLDPTFRSSSTTSNRSLPSRPGIPSPLASGSARSTTSGTAQRQAGQRPSSRLGLKASRRDSEARPLSPSMIPVPSFSSRPMSPDVYQPLRSATPTSGFSSFSASASTSNPPRPNSRTGKRNPIGRGPPPLSSSTRLHHQRSRQSLSGAGPTPTTGADKVERAKRGPRRSSLSNMDKPSLMSASSGSRTPSGRPTSVHVFRETPPPVPRIPSAILKESKVKK

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
635 amino acids
Function
Required for nuclear migration.
Similarity
Belongs to the nudE family.
Mass
68.418 kDa
Sequence
MSEHGADLRFDSPEKEIKHWKSKVADMQDALRETESSLQDFVESSKELEQEMEKELSASNKTISDLKRRNEQLSGDLEDWKSKYSRALSEHNATLTTLQKELGQLRESVDIYKAKLRDTELTNDELENAERMVASSLADMEGKYNKTIEKTALLEEELIEKTRLDEENQRLKDELREMTEEMTILRDLVTRSRAISRADTMASSTYDDSTAPRSEQSFDSSPIKPSSAARATERPSSRQALSSPVTNRVPISRRLGAMGHNRRLSRDVRAAEAPSLAAVLDDSPTATTTSAAPTRSSTLSRRDPLAATPYHHGASTSHGLTSSPSARAQLRASVRAAARIGGAVSVSSAPRSTNLSANGGAAGSKRMMAEMISKMKALESRINSAKDLSRVVGPGDESAIPRPSSRMATIGSPSANGHNSIHMPTSTPRAPRASMDGNRTIGSSIPVPSRVRRPSSRMSERGTPPMPSLGLPRAQTPSSLHARGSSRADGPSPLPLHEFMDHDPASTLPHAARYAAAQASVAKRRTSMSGSGMSHSASHGSLAKVRSGSTLPRSTTPSTVAAPRVTQSSMTYYGAEASMSKRTPLSTRLASSHRNASSARGSINGPPSSWKTSAMPAQTLSRSRSSSLGSETETF

Gene
nde1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
621 amino acids
Function
Required for nuclear migration within hyphae during vegetative growth.
Similarity
Belongs to the nudE family.
Mass
68.763 kDa
Sequence
MPSADGSSSARPNGTSSRSDQLAWYKSQYEQLEAELADFQASSRELEAELEKDIEASEKRERLLKEKVDSLKYEVEEWKVRLEFTTFIADDGPRANLSLPRQTKYKQSKAEGNSAQNTLQKEITTLRDANRTLQLKLRDIEVANDDYERQARHTTSSLEDLESKYNVAIERAVLLEEEMRAGEQEREKLRIENQRLRDELSDLKIETEIIHEKLRNAELQNSRRRKPISLRSPSTPQTPDLFNRSPASSIVSSPLFSTPTLKTSLMSATATPPSPPISESSSSLRKSMNAMPGFPLQKASASDSSFGSRSLHGSRTQKHNNHSRATSYAFTSNRPTPSVTNRPGLPKPKPKPNENTNKHNNNARSSGLPKSGSLYQIRGLIGKMQKLEERVQSAKSKLPPPSDSPSRTSSRSGSILGESPVASTITARRNSRKRLSGSSFSSSVRDGDSVPSYAPHSRPSFGARTQGDSRPSSRTSYSSHSSVSHSTHPSVTPSTRPESRQSRTKTPLGHYSTNPTTESRRPRSSLSNPSNQNGVVNGMAHIDEDEDLAMHMSLRARISEIRETRLPSISTPTGLKKRTPSGISGIPAPRTLRTSTGFDRLEGDMGPPERKSNITDLGETY

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
583 amino acids
Function
Required for nuclear migration.
Similarity
Belongs to the nudE family.
Mass
63.65 kDa
Sequence
MASEPPSSPPGAGATLEDTLGWYKSQYEQLESELAEFRDSSRELEQELEKDIERAEKQERHHQEKAETLGFEVEEWKRKYRESKTEASASQNALEKEITTLRDTNRTLQLKLRDIEVANDDFERQARNTTSSLEDMESKYNQAIERAVMMEEEIKIGEQEREQLRIESQRLREELGDLKIEAELLQDKFKKQESRHLSTISTDLSVLASPTFDGHPASPGSTASSPLITTPTDSKSMTEDGDTLSELPDPPSPPMSDVSAPLPKVAASRPSAHRRTVSRSRLPSTDISTTPLPRSKPPTATTRAPGSRISTGGTTTMRTPAQRAVGPRSASNKLPTSNSLTHIRTLTAQMQRLEARVHSVRSKLPGPTRTPPRASPRTNVYSATNMPASITIRSRKRTSGSAASSVTGDDPTPTNIPTSTPKGSHVPRLSTSGVSRLSFGPLPNRGGPDEISRPSSRASTSYATSYARPPSRAAGEGIPRPISRASLTGVRTPMGRSRSSMGFHGHSASISSHLDLEEQDEGEFRTPSRRGTYSSQGGEVSGSGIPMPATRRRSGSRRISASTMRSSVSGPPRKQLSDLGETY

Gene
NDE1
Protein
External NADH-ubiquinone oxidoreductase 1, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
560 amino acids
Function
External NADH dehydrogenase required for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol. With NDE2, performes the mitochondrial oxidation of cytosolic NADH under these growth conditions. Regulates the mitochondrial glycerol-3-phosphate dehydrogenase, GUT2, also involved in cytosolic NADH oxidation.
Similarity
Belongs to the NADH dehydrogenase family.
Mass
62.774 kDa
Sequence
MIRQSLMKTVWANSSRFSLQSKSGLVKYAKNRSFHAARNLLEDKKVILQKVAPTTGVVAKQSFFKRTGKFTLKALLYSALAGTAYVSYSLYREANPSTQVPQSDTFPNGSKRKTLVILGSGWGSVSLLKNLDTTLYNVVVVSPRNYFLFTPLLPSTPVGTIELKSIVEPVRTIARRSHGEVHYYEAEAYDVDPENKTIKVKSSAKNNDYDLDLKYDYLVVGVGAQPNTFGTPGVYEYSSFLKEISDAQEIRLKIMSSIEKAASLSPKDPERARLLSFVVVGGGPTGVEFAAELRDYVDQDLRKWMPELSKEIKVTLVEALPNILNMFDKYLVDYAQDLFKEEKIDLRLKTMVKKVDATTITAKTGDGDIENIPYGVLVWATGNAPREVSKNLMTKLEEQDSRRGLLIDNKLQLLGAKGSIFAIGDCTFHPGLFPTAQVAHQEGEYLAQYFKKAYKIDQLNWKMTHAKDDSEVARLKNQIVKTQSQIEDFKYNHKGALAYIGSDKAIADLAVGEAKYRLAGSFTFLFWKSAYLAMCLSFRNRVLVAMDWAKVYFLGRDSSI

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
461 amino acids
Function
Required for nuclear migration.
Similarity
Belongs to the nudE family.
Mass
50.801 kDa
Sequence
MTDIDTPASPLTPNSKAHLEVIAYNQYLQAKEQIQQLEHELTEFQESSKELELELEQELAESDKRQAKLEDRISALESEVTEWRKKALDAHKEAASTQQALQREVSSLRDAHKLVKERLRETENANDDIEQRERITCSTLEDIQTRYNEALENVAILEAELAAKDVLIGEHHRAKEEIKDLTEELEHTRKKLAIRDQELEDANKRIMNPPPATNHNATTHRRAVSGTAQVSAEGYLTPLTSTGAKPLSSSRSMQFIHGLQSQMRSLESRVAHVKSSLPKPTTPKRAKSSASAVSGASTIKSSPSMALLTRKLSEADDVVSLSPSRSTSSLEDLCTPSPSPQVARRDMSGGGSRLDLRADPRLNGRPKTQQPRPSYNSALATAKPLDPIEGSPTSLEGRNRTRSASPTKKLSSLSLNAPSLPQSQARVNIPALMRPASPIKQPSPPKPAPGSKFADVYGRRR

Gene
nde1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Xenopus tropicalis
Length
349 amino acids
Function
Required for centrosome duplication and formation and function of the mitotic spindle.
Similarity
Belongs to the nudE family.
Mass
39.553 kDa
Sequence
MDDLENNIFNSVEEEIIYWKSVAMKYKTCSEEAQQELQEFQEASREYEAELEAQLQQIEGRNRDLFSENNRLRMELDGIKEKYEEQHSENYVQICSLEGDLSQTKAVRDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPKSNMGSPETERMDTSVKASVAIPSAPLTPLSQRGCASTLTSPLSFRTSLDDGYSGTPLTPCARISALNIVGDLLRKVGALESKLASCRNFVHEQSPNRPLTSVSARMNKTREGIENRLSMASGSSVEKGLIKRLEFGSLPSNTPVQGMHSPQGVVKMII

Gene
Nde1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Mus musculus
Length
344 amino acids
Function
Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.
Similarity
Belongs to the nudE family.
Mass
38.523 kDa
Sequence
MEDSGKTFESEEEETNYWRDLAMTYKQRAENTQEELREFQEGSREYEAELEAQLQQIETRNRDLLSENNRLRMELESVKEKFEMQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQDKPRTPMPGSGQAKRTDMAVQATGSVPSTPVAHRGPSSGLNTPGMFRRGLDSSTSGTPLTPAARISALNIVGDLLRKVGALESKLASCRNFMYDQSPSRTSGPASGRGTKNRDGVDRRPGSTSVGDKGSGKRLEFGKPASEPASPALPSAQGVVKLLL

Gene
Nde1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Rattus norvegicus
Length
344 amino acids
Function
Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex (By similarity).
Similarity
Belongs to the nudE family.
Mass
38.528 kDa
Sequence
MEDSGKTFGSEEEETNYWRDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQAETRNRDLLSENNRLRMELESVKEKFEMQHSEGYRQISALEDDLAHTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQDKPRTPMPSSGETKRTDMAVQATGSAPSTPITHQGSSSGLNTPETFRCGLGSPSSGTPLTPAARISALNIVGDLLRKVGALESKLASCKNFMYDQSPSRKSGPALGRGTKNRDGIDRRPGSTAVGDKGSGKRLEFAKPSSQLSSPALPSTQGVVKLLL

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Gallus gallus
Length
342 amino acids
Function
Required for centrosome duplication and formation and function of the mitotic spindle.
Similarity
Belongs to the nudE family.
Mass
39.564 kDa
Sequence
MEDSEEHHFSSVEEETRYWKELAMKYKQCAENIQEELCEFQEGSREYEAELETQLQQTESRNRDLLSENNRLRIELESVKEKFEMQHSEWYRQVSALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAAIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPKTPMRTSLETERTDTAVQASLSLPSTPSLHRAPNINIPTPATFRRGFEDSYCATPLTPAARISALNIMGDLLRKVGALESKLASCRNFVYDQSPDRTTVSMYMNRDALETRMSPHQPLCDTGLVKRLEFGTRPSSTPGPMSHPSQSVVKMLL

Gene
NDE1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Homo sapiens
Length
335 amino acids
Function
Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.
Similarity
Belongs to the nudE family.
Mass
37.721 kDa
Sequence
MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDGGERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC