msl-3

Protein male-specific lethal-3

543 amino acids

The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation).

62.126 kDa

MTAHENEVQLFNRGEKVLCYEPDESKARVLYDSKVLAVYERKDAANLRYFDYKIHFQGWNSSWDRNVRAASLLKDNEENRKLQRELAEAAQLQKTGGYSYKDSKTPTLPSSKKKRLARGGHVEDPTADPLDISLPSSKKKRLARGGHVEDPTADPLDISLAHLPATPKPELPAQQKRGARSRDGSGNRSRDGSGNRSRDNSSGRKKQRDKSKGGDKNDDGERRSARSQFSLHVSPKDTHTTDAEKRIHQEDRVMLRISERLREYMEYDYNMVCKLEKQHALPARTPIVTILENFVKQRAVELAIGIKQDSSRARNTLSRNARMEREYDRVMSIVCMLKEVVDGLRIYFEFHLEDHLLYREEKDYALGFLTDNNMKNCSLLLNKSYEFINPSGDNELISMAGNVNGTNGVDGPLLGDIEYENQLQKCLRYIEKNSAKNNIALAYTAAYKLPMEMRGFLRETFSWSLLSEESPPEKSIIFGAPHLARMLVLLPECLNASPISNEKLVDLLPHLDSFINYLENHKEWFDKQNYLDPLIDQGRELSV

msl-3

Protein male-specific lethal-3

512 amino acids

The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.

58.853 kDa

MTELRDETPLFHKGEIVLCYEPDKSKARVLYTSKVLNVFERRNEHGLRFYEYKIHFQGWRPSYDRCVRATVLLKDTEENRQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEPIVVPMDTGHLEAEHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGNRGRQTETFYNNAINDVSVYNHVPQEDRIMMRVSERLRELIEYDRNMIKVLGKQHALPARVPIVTIMENFVKQQAVELAISIKQDSSRARNTQSRNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYTEEKEYVHNYLTDDNMRNCSLILNKSYEYINPSGDTELIGLDGTPVVEGSGDTNGQIGVINIGGPEYEKQLQKCLLYIVTASGKNTAQAYERTSPYTAAYKLPVEMRGFLNETFKWRLLSAESPPEKSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENFVNSTALPQEDLQRELLDSLDGIAA