Protein
G1-specific transcription factors activator MSA1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
Activator of G1-specific transcription factors, MBF and SBF. Promotes both the timing of G1-specific gene transcription and cell cycle initiation. Associates with SBF- and MBF-regulated target promoters and this binding is maximal during the G1 phase, prior to maximum budding. Affects cell cycle initiation by advancing the timing of transcription of G1-specific genes. Overexpression advances the timing of SBF-dependent transcription and budding. Depletion delays both indicators of cell cycle initiation.
Sequence
MDKSMIKKRGRPPITKDYPNPLQSPMAHSSMQVQKQGPHSFAKPLMKVGQSSPSPNKRRLSIDHHHNLAATTRKGRYRGVLLSTPTKKSSTNGSTPISTPSSNDSYNNTVFSETRKTFLQSSPPIMTSSPAFQKKNDYMFPSQEQFKLSLTITESGKAVIAGSLPFSPSSKSSHLMNNNNKKIMQNEKIHKGSKKNAPKFEKRRILSLLKQMKNEKYCDTDTLPEAPPAKPSRSDIIDTELPTIIETSASPIGSARNNNILLSQPPQSPPSSAQLKPPSTPKSSLQFRMGFTPNVALNSVSLSDTISKSTNAVGASNNNNQNGNSISNIADANTLLTLTNSPGVFLSPRNKMLPKSTTASNEQQQEFVFKFSSGDPLLLTDDADGNWPEMLFNVSNTPRRQKCFNTPPSWINFGSPGLFSPPRSSNVMVNGTTVATASDSGNVHRQLQAQLEAQVQVQSQSNSPTQRQQQQRQFQIPPPHINMNSSPPQINIASPPHQSMSRVSSIYFNKEKTTTGVANMLGNTKSENLQPPANLFTAAHGPSTPRNQEFQLPTLIECTPLIQQTMNGSLGTKYIPGTSISNSATPNLHGFPVGTGKAPSSFDDSLKQNPYSNKQDDARTALKRLIDDQ