mrcA

Penicillin-binding protein 1A

853 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

94.221 kDa

MRIAKLILNTLLTLCILGLVAGGMLYFHLKSELQQPMQIYTADGKLIGEVGEQRRIPVKLADVPQRLIDAFLATEDSRFYDHHGLDPIGIARALFVAVSNGGASQGASTITQQLARNFFLTSEKTIIRKAREAVLAVEIENTLNKQEILELYLNKIFLGYRSYGVAAAAQTYFGKSLNELTLSEMAIIAGLPKAPSTMNPLYSLKRSEERRNVVLSRMLDEKYISKEEYDAALKEPIVASYHGAKFEFRADYVTEMVRQEMVRRFGEENAYTSGYKVFTTVLSKDQAEAQKAVRNNLIDYDMRHGYRGGAPLWQKNEAAWDNDRIVGFLRKLPDSEPFIPAAVIGIVKGGADILLASGEKMTLSTNAMRWTGRSNPVKVGEQIWIHQRANGEWQLGQIPAANSALVSLNSDNGAIEAVVGGFSYEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPISIQKPGQKMWQPKNSPDRYDGPMRLRVGLGQSKNIIAIRAIQTAGIDFTAEFLQRFGFKRDQYFASEALALGAASFTPLEMARAYAVFDNGGFLIEPYIIEKIQDNTGKDLFIANPKIACIECNDIPVIYGETKDKINGFANIPLGENALKPTDDSTNGEELDQQPETVPELPELQSNMTALKEDAIDLMAAAKNASSKIEYAPRVISGELAFLIRSALNTAIYGEQGLDWKGTSWRIAQSIKRSDIGGKTGTTNSSKVAWYAGFGANLVTTTYVGFDDNKRVLGRGEAGAKTAMPAWITYMKTALSDKPERKLSLPPKIVEKNIDTLTGLLSPNGGRKEYFIAGTEPTRTYLSEMQERGYYVPTELQQRLNNEGNTPATQPQELF

mrcA

Penicillin-binding protein 1A

850 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

93.636 kDa

MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDASAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF

mrcA

Penicillin-binding protein 1A

825 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

91.987 kDa

MKFIKRLLVFSLICIILGVTTIFGFYFYVKSDLPDVATLRDVQLQTPMQVFSQDGKLIAQFGEKRRIPLKLEEMPKELIEAVIATEDSRYYEHYGFDPIGITRAAFAVLASGSASQGASTITQQLARNFFLSNEKKVMRKVKEIFIAIHIEQLLSKQEILELYLNKIYLGYRSYGVGAAAQAYFGKEVKDLTLGEIALIAGLPKAPSTMNPIYSVERATNRRNVVLQRMLDEKYITKAEYDAARAEPVLPKYHGAEIELNAPYVAEIARAWMVERYGEEAAYTSGMNVYTTVDSKLQRAANQAAINNLLAYDERHGYRGAEKELWQVNQPAWSSTQLSEYLSNEPTYGDMFPAAVLSVEEKSAQVWVKSYGVQTIAWEDMNWARRFINDDRQGPLPKSANEFLAAGQQIWVRPRTQDGAITAWKLTQVPNANTAFVAMNPENGAVTALVGGFNFVHNKFNRATQSVRQVGSSIKPFIYSAALNKGLTLATLINDAPINQWDESQGTAWRPKNSPPTYTGPTRLRIGLAQSKNVMAVRVLREVGLDETREYLTRFGFKLDQLPRSETIALGAGSLTPVQMAQGFSVFANNGYFVEPFYISRVENPFGNIEFSAEPKVVCHRECSSELDEFAEQDAASPYAPKVISEQNAFLTREMLYSNIWGGGEWSSDTGWNGTGWRAQALKRRDIGGKTGTTNDSKDAWYNGYAPGIVGVAWVGFDDHSRNLGKTAPNRNIEDDVSGAESGGKTALPAWVEFMSLALQDVPVQQKAVPNNIARVRIDRDTGLLTNKLDSSSMFEYFEAGTEPTEYVSEHVNESIYSTSSGEELF

mrcA

Penicillin-binding protein 1A

822 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

91.2 kDa

MRLLKFLWWTCVTLICGVLLSFSGAYLYLSPSLPSVEALRNVQLQIPLKVYSEDGKLISEFGEMRRTPIRFADIPQDFIHALLSAEDDNFANHYGVDVKSLMRAAAQLLKSGHIQTGGSTITMQVAKNYFLTNERSFSRKINEILLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKPIKDLSLAEMAMIAGLPKAPSRYNPLVNPTRSTERRNWILERMLKLGFIDQQRYQAAVEEPINASYHVQTPELNAPYIAEMARAEMVGRYGSEAYTEGYKVITTVRSDLQNAASQSVRDGLIDYDQRHGYRGPETRLPGQTRDAWLKHLGQQRSIGGLEPAIVTQVEKSGIMVMTRDGKEEAVTWDSMKWARPFLSNNSMGPMPRQPADVAQAGDQIRVQRQEDGTLRFVQIPAAQSALISLDPKDGAIRSLVGGFSFEQSNYNRAIQAKRQPGSSFKPFIYSAALDNGFTAASLVNDAPIVFVDEYLDKVWRPKNDTNTFLGPIPLREALYKSRNMVSIRVLQGLGIERAISYITKFGFQRDELPRNFSLALGTATVTPMEIAGAWSVFANGGYKVNPYVIERIESRDGQVLYQANPPRVPVEEQVAADAEDAGNPGDPEHPESAEGEGSIEAQQVAAKAQTTFEPTPAERIIDARTAYIMTSMLQDVIKRGTGRRALALKRTDLAGKTGTTNDSKDGWFSGYNSDYVTSVWVGFDQPETLGRREYGGTVALPIWIRYMGFALKDKPMHTMAEPPGIVSLRIDPVTGRSAAPGTPGAYFEMFKNEDTPPSVNELPPGSFPGSPLPDDEGAPIDLF

mrcA

Penicillin-binding protein 1A

809 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

90.224 kDa

MYRLRGWLGWLLTILIILTLVGILAAGGMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLMAIFGEIRRYPVQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNFITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAVVVRSDRSELTLPPAAARWTGTPLNKLLKRGDVVRVRPGEKWGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASIVPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGVDFARNYITQFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNTPKVACRSCTSANTNVTQSTSQLVDGFNFGAPTKTEPSKPVKNNNEPPQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYVTTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNVPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEESDEQTFDIF

mrcA

Penicillin-binding protein 1A

809 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

90.178 kDa

MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYPVQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNFITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDVVRVRPGEKRGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASIVPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKPVKNNNEPTQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYVTTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEESDEQTFDIF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

87.843 kDa

MIKKIVTTCFGLVLGLCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGIYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYQHWGVDVWGVARAVVGNIVAGGVQSGASTITQQVAKNFYLSSEKTFTRKFNEALLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKDVRELTLAEVAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITLQQRDQALNEELHYERFVQKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRTDHQKVATEALRKALRNFDRGSSYRGAESYIDLSKGEDVEETVSQYLSGLYTVDKMVPAIVLDVTKRKNVVIQLPSGKRVTLDGRSLGFAARAVNNEKMGESRIRRGSVIRVRNNGGRWVVVQEPLLQATLVSLDAKTGAVRALVGGYDFHSKTFNRAAQAMRQPGSTFKPFIYSAALSKGMTASTMVNDAPISLPGKGANGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAHEYIQRFGFKPSELPASLSMALGTGETTPLKIAEAYSVFANGGYRVSSHVIDKIYGSDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRSDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGGQGKGMKVPEGVVSSNGEYYMKERMVTDPGLVVDNSGIAAQPSRRIREDKEAGAEDVERGAADEVRQEVQETPVLPSNTGSKQPQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

87.704 kDa

MIKKIITTCMGLNNGLALFGVGLIAIAILVTYPKLPSLDSLQHYKPKLPLTIYSSDGQVIGVYGEQRREFTKIDDFPKILKDAVIAAEDKRFYDHWGVDVWGVARAVIGNVMAGGVQSGASTITQQVAKNFYLSSERSFTRKFNEALLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQTYFNKNVNDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQAYILNNMLEEGMITLQQRDQALKEELHYERFVQNIDQSALYVAEMARQELFEKYGEDAYTQGFKVYTTVDTAHQRVATEALRKVLRNFDRGSSYRGAENYIDLSKSDNVEETVSQYLSTLYTVDKMIPAVVLEASRKGVQIQLPSGRKVTLNNHALGFAARAVNNEKMGDDRIRRGSVIRVKGSGDTFTVVQEPLLQGALVSLDAKTGAVRALVGGYDYHSKTFNRATQAMRQPGSTFKPFIYSAALAKGMTASTMINDAPISLPGKGANGKAWNPKNSDGRYAGYITLRQALTASKNMVSIRILMSIGIGYAQQYIQRFGFKPSEIPASLSMALGAGETTPLRIAEGYSVFANGGYKVSAHVIDKIYDSQGRLRAQMQPLVAGENAPQAIDPRNAYIMYKIMQDVVRVGTARGAATLGRSDIAGKTGTTNDNKDAWFVGFNPNVVTAVYIGFDKPRSMGRAGYGGTIAVPVWVEYIGFALKGTSVKPMKAPEGVVTNGGEVYMRERMTTSSDLALDNSGIRPRPTQPARRAVPNENRRRAESNTAPAREESDETPVLPSNTGNNNRQQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). Essential for cell wall synthesis.

In the C-terminal section; belongs to the transpeptidase family.

88.495 kDa

MIKKILTTCFGLFFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRRELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAPQPSRRAKEDDEAAVENEQQGRSDETRQDVQETPVLPSNTDSKQQQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). Essential for cell wall synthesis.

In the C-terminal section; belongs to the transpeptidase family.

88.495 kDa

MIKKILTTCFGLFFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRRELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAPQPSRRAKEDDEAAVENEQQGRSDETRQDVQETPVLPSNTDSKQQQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.109 kDa

MIKKIMTTCFGLVFGLCVFAVGLLAIAILATYPKLPSLDSLQHYQPKMPLTVYSADGKIIGIYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYQHWGVDVWGVARAVVGNIVSGSMQSGASTITQQVAKNFYLSSEKTFTRKFNEALLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKDVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITLQQRDQALNEELHYERFVQKIDQSALYVAEMVRQELYEKYGEDAYTQGLKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAESYIDLGRDEDAEEAVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGKRVTLDRRALGFAARAVDNEKMGEDRIRRGAVIRVRNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRATQAMRQPGSTFKPFVYSAALSKGMTASTMINDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFKPSELPVSLSMALGTGETTPLRIAEAYSVFANGGYRVSSYVIDKIYDSEGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGASALGRSDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGRPGKGMKMPDGVVAGNGEYYMKEHMVTDPGLMLDNGGAAPQPSRRVKEDDGGAAEGGRQEADDESRQDMQETPVLPSNTDSKRQQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.148 kDa

MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLTLDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF

mrcA

Penicillin-binding protein 1A

798 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.148 kDa

MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLTLDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF

mrcA

Penicillin-binding protein 1A

791 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.946 kDa

MYKSLFFCLKILALLFLIGCGIVAYIIYYYSRDLPDYRQLARYYPPSVTRIYSRDGKLMEEYAFERRVFIPINSIPTSLKESFIAAEDKNFYNHQGVDLFGIVRAAFLNISNFLHHRRMEGASTITQQVVKNFLLTNEVSFQRKIKEAILSYMISRVFTKDQILELYLNQTFFGRGAYGVATAAQNYFNKSVEELTIAESAFIAALPKAPSELNPEKNYARVKARRDYVIMRMLEDGYITSDAAKEAVDSPITLRKRDQDETVTADYYAEQVRDEVIKMLGSKDEFYTSGLTIITSLDAKMQKFAEESLRKGLRDFDRKRGFRKAIATISLDNWQEELKKLPTTPSLLEYKIAVVLEVTDTQAEIGFASGAKSKIPISEMKWAKSELKSAKKLLTKGDVIVVEPVKDYYALRQIPEVNGAIMVMNPNTGQVLTSVGGYDFFASKFDRVTQALRQPGSLSKTFVYLAALENGVKPNQIFNDGPIEISQGPGMPSWRPKNYEGKFLGPITMRTGLEKSRNLVTVRVATAVGLTKIVDIIKRFGINDNPQKVYSMVLGSIETTLERITNAYGIIANGGKRIKPHFVELIKDRNGKVIYRRDDRECTTCNVSDNDLDNAILEIPAENIYMVTDAASDYQITSLLTGVVDRGTAYSAKKLGKVIGGKTGTSNDSKDTWFIGFTPKIVVGSYVGYDTPRTLGRRATGSSVVLPIFIDFMSNAYKDEPPLPFKVPDSVKLQAVDRATGQITPSGSVMEAFKINNILIIEDDSEIIDNNHNNDVFDYVPTEKDQSQEIY

mrcA

Penicillin-binding protein 1A

790 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.684 kDa

MYKSLLFCLKIFVFLILVGCGITAYIIYHYSRDLPDYSQLARYYPPSVTRIYSRDGKLMEEYAFERRVFVPINSVPSSLIESFIAAEDKNFYNHPGVDLFGIVRAAFLNISNYLHHRRMEGASTITQQVVKNFLLTNEVSLERKIKEAILSYMISRVFTKDQILELYLNQTFFGRGAYGVAVAAQNYFNKSVEELTIAESAFIAALPKAPSELNPERNYARVKARRDYVITRMFEDGYITRDAAKEAMDSPIVLRKRAKEETVTADYYAAQVREEVIRMLNSKEVFYTGGLTIITSLDAKMQQLAENSLRKGLREFDRRCGFRKPIANISLDNWQGELKKLPTPPSLLEYKLAVVLDVADNHVEIGLIDGSKSKMPIAEMKWARSNFKSVKTLLKKGDVIVVEAIKEGYALRQIPEVNGAIMVMNPNTGQVLASVGGYDFSTSKFDRVTQALRQPGSLSKTFVYLAALENGVKPNQIFNDGPIEISQGPGMPSWRPKNYEGKFLGEITMRTGLEKSRNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRMTNAYAIIANGGKKVEPHFVELIKDRNGKIIYRRDDRECLACNVSDSNLDTAILEIPKEYIYRVTDEASDYQITSFLTGAIDRGTGYAAKKLGKIIGGKTGTSNDSKDTWFVGFTPKIVVGSYVGYDTPKELGKRATGSNVVLPIFIDFMSNAYKDKPSLPFKVPDSIKLIAVDSATGKITPGGTVIEAFKVNNVQMLENEDMIDNQDNNDIFDYVPSKEDQSQEIY

mrcA

Penicillin-binding protein 1A

790 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.742 kDa

MYKSLFFCLKIFAVLILVGCGITAYIIYHYSRDLPDYSQLARYYPPSVTRIYSHDGKLMEEYAFERRVFVPINSIPSSLIESFIAAEDKNFYNHPGVDLLGIVRAAFLNISNYLHHRRMEGASTITQQVVKNFLLTNEVSLERKIKEAILSYMISRVFTKEQILELYLNQTFFGRGAYGVAAAAQNYFNKSVEELTIAESAFIAALPKAPSELNPERNYARVKARRDYVIARMFEDGYITKDAAKEAMDSPIVLRKRAKEETVTADYYAAQVREEVIRMLNSKEEFYTGGLTIITSLDAKMQQLAENSLRKGLREFDRRRGFRKPIANIPLDNWQEEIKKLPSPPSLLEYKLAVVLDVADNHAEIGLIDGSKSKILIAEMKWARSNLKSVKTLLKKGDVIVVEPIKDGYALRQIPEVNGAIMVMNPNTGQVLASVGGYDFSTSKFDRVTQALRQPGSLSKTFVYLAALENGIKPNQIFNDGPIEISQGPGMPSWRPKNYEGKFLGEITMRTGLEKSCNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRMTNAYAIIANGGKKVEPHFVELIKDRNGKIIYRRDNRECLSCNVSDSNLDIAILEIPKEDIYRVTDEASDYQITSFLTGAIDRSTGYAAKKLGKIIGGKTGTSNDSKDTWFVGFTPKIVVGSYVGYDTPKELGKRATGSNVVLPIFIDFMSNAYKDEPSLPFKVPDSIKLIAVDRATGKITPSGTVIEAFKVNNIQMLENEDMIDNRDNNDIFDYVPSKEDQSQEIY

mrcA

Penicillin-binding protein 1A

787 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.694 kDa

MYKSLFLCLKIFAVLILIGCSVTAYIIYHYSHDLPDYSQLARYYPPSVTRIYSRDGKLIEEYAFERRVFVPINNVPSSLIESFIAAEDKNFYTHPGIDLLGIVRAAFLNISNYLHNRRMEGASTITQQVVKNFLLTNEVSLERKIKEVIISYMISRIFTKHQILELYLNQTFFGRGAYGVAAAAQNYFNKSVEELTIAESAFIAALPKAPSELNPDKNYSRVKARRDYVIERMFEDGYITRDTMKEAIGSPIVLRKRAKEETVTADYYAEQVREEVIRMLNSKEEFYRGGLTIITSLDAKMQQLAENSLRKGLREFDRKSGFRKPIANIPLDNWQEELKKLPTPSSLLEYKLAVVLDVSDNHAKIGLIDGSKAKIPIVEMQWARSNLKSVKTLLKKGDVIVVEPIKDCYALRQIPEVNGAIMVMNPHTGQVLASVGGYDFSTSKFDRVTQALRQPGSLSKTFVYLAALENGVKPNQIFNDGPIEIIQGPGMPSWCPKNYEGQFLGDMTMRTGFEKSRNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRITNAYAIIANGGKKVEPHFVELIQDRNGKIIYRRDNRECFSCNIADSDLDTAILEIPKEDIYRVTDEASNYQITSFLTGAIDSGTGYAARKLGKIIAGKTGTSNDSKDTWFIGFTPKIVVGSYVGYDTPKELGKKATGSNVVLPIFIDFMNHAYKDEPSLPFKVPDSIKLIAVDRITGKMIPNGTVIEAFKVNNIQMLENDYMIDNHDIFDYVPGMLDQSQEIY

mrcA

Penicillin-binding protein 1A

785 amino acids

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

In the C-terminal section; belongs to the transpeptidase family.

88.677 kDa

MYKSLFFFLKIFAILILLGCSVTAYIIYHYSHDLPDYSQLVRYYPPSVTRIYSRDGKLMEEYAFERRVFVPINNVPSSLIESFIAAEDKNFYNHPGIDLLGIVRAAFLNISNYLHNRRMEGASTITQQVVKNFLLTNEVSLERKIKEVIISYMISRVFTKHQILELYLNQTFFGRGAYGVAAAAQNYFNKSIEELTIAESAFIAALPKAPSELNPDKNYSRVKARRDYVIERMFEDGYITRDTMKEAIGSPIVLRKRAKEETVTADYYAAQVREEVIKMLNSKEEFYRGGLTIITSLDAQMQKLAENALRKGLREFDRRHGFRKPIANIPLDHWQEALKNIPTPSSLLEYKLAVVLDVSDNHAKIGLIDGSKARIPIIEMQWARSNLKSVKTLLKKGDVIVVEPIKDCYALRQIPEINGAIMVMNPHTGQVLASVGGYDFSTSKFDRVTQALRQPGSLTKTFVYLAALENGVKPNQIFNDGPIEIMQGPGMPSWRPKNYEGQFLGEMTMRTGFEKSRNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRITNAYAIIANGGKKVEPHFIELIKDRNGKIIYRRDNRECFSCNILDSDLDTAILEIPKEDIYRVTDEASDYQITSFLTGAIDSGTGYAARKLGKIIAGKTGTSNDSKDTWFIGFTPKIVVGSYVGYDTPKELGKKATGSNVVLPIFIDFMNHAYKDEPSLPFKVPDSIKLIAVDRITGKMIPDGTVIEAFKVNNIQMLENDYMIDNHDIFIPGISDQSQEIY

mrcA

Penicillin-binding protein 1A

726 amino acids

In the C-terminal section; belongs to the transpeptidase family.

81.824 kDa

MKKLVIGILGIVIALFVGLLVFLIPIYKNLPDPKLLESWTPPQASEVYDAKGRLYGTIGIQKRFYVSIDKIPEHVINAFVATEDRNFWHHFGIDPVAIVRAAIVNYRAGRIVQGGSTITQQLAKNLFLTRERTLERKIKEALLAIKIERTFDKKKIMELYLNQIYLGSGAYGVEAAAQVYFGKHVWELSLDEAALLAALPKAPAKYNPFYHPERALQRRNLVLKRMLEEGYITPEQYEEAVNKPLTVKKENKYKFSDYFLDMVKSYVFNKYGEIAYKGRLKIYTTIDLDYQKIAQKSLEEGLKRVAKIIGLPFLPKSEEDMELAYEKEAQLKRLKRGKIYVAKILKYDGNFMKVEIHGKKLKGEIKGLNTEGHKYVFVKYLGGNRAEIIPDLEGSLVSIDVKTGEIKAIVGGRSYAYSQFNRAVKALRQPGSAIKPVIYLSALLKGMTQISTIDASSKPYYDPSKGEDWIPKNYDEKEYGNVTLRYALAHSINTAAVNLLDKVGFELVLEVGKKVGLDNLKPYYSLALGTVEVTPLQLTAAYQVFANLGTECKPFFIKKIVDENGEVLEENVPECEEVLPKPETRVPVDMLRAVVLEGTARRASVLDRIVAGKTGTTDDFQDAWFVGFSPYIVTGVWVGYDVKKSLGKHMSGSRVALPIWIDYMKVVTRMYPNEDFELPPENIVVNINPKDLVLADETCEGVPMVFVKGTEPHITCSDLNAILGLR