About Products Protein Database Contact

mqnE

Gene
mqnE
Protein
Aminodeoxyfutalosine synthase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
387 amino acids
Function
Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
Similarity
Belongs to the radical SAM superfamily. MqnE family.
Mass
44.42 kDa
Sequence
MDAGLKRELEQKVRSGERLTREDGIALYESDDLAWLGGLAHEVRTRKNGDVVHFNVNRHLNMTNVCTASCAYCSFQRKPGEKDAYTMRIEEAVKLAKAMEGENLTELHIVNGLHPNLPWRYYPRSLRELKAALPEVSLKAFTATEIHHFETISGMSASDILDELIDAGLESLTGGGAEIFDWEVRQHIVDHRTHWEDWSRIHRLAHEKGLKTPCTMLYGHIEEPRHRVDHVLRLRELQDETGGFQVFIPLRYQHDFVDMKDGKVRNRLQARTQMATGAEALKTFAVSRLLFDNVPHVKVFWVMHGVQTAQLALQHGADDMDGSVVEYKITHDADDFGTPNKLTREDLLDLIRDAGFRPVERNTRYEILREYEGPDPARRESPQPMRV

Gene
mqnE
Protein
Aminodeoxyfutalosine synthase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
372 amino acids
Function
Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
Similarity
Belongs to the radical SAM superfamily. MqnE family.
Mass
42.613 kDa
Sequence
MRGIRDPRLIPIAEKVMEGKRLSFEDGLVLYQTKDLPTLMRLANLVRERKHGHKTYFVHSIRVSQTNICYVGCTFCAFQRRFGEEGAWDWDVDEVVAWVKERYQPGLTEIHLTAGHHPKRPFAYYLDLVRALKENFPGVQVKAWTAAEIHHFSKIARLPYREVLKALKEAGLDAMPGGGAEIFAERVRRKIARAKVSAEGWLEIHRTAHELGIPTNATMLYGHIETLEERLDHMDRLRRLQDETGGFMSFIPLAFQPDGNQLARELGKKEFTTGLDDLRNLAVARLYLDNFPHIKGYWATLTPELAQVSLDWGVTDVDGTLIEERIVHMAGSPTPQGLTKRELARIILMAGRIPVERDALYREVRVWDRVEA