mptE

6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

241 amino acids

Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

Belongs to the archaeal 6-HMPDK family.

27.581 kDa

MDMKEWEIFYNKIMEDFGFDKDKDVESAVILNNILENANTIPVDKLKDIIEGREVFIFGAGPSIKKHINILKELREINYKNPIIVADGACKAFLEENIIPDIIVSDLDGDLEALFECNRKGSIIVVHAHGDNIEKIKKYVPKLKNVVGSCQIPNYKELNLRNVINFGGFTDGDRCCFLAYHFKAKKLILGGMDFGIYITKYSRPNIKEDIAIGDEIKIKKLEYAKTLINYLKDKIEIEFLK

mptE

6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

232 amino acids

Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

Belongs to the archaeal 6-HMPDK family.

25.95 kDa

MEVQVWLRWYTRILDDFGFDRRADEESASYLDAFLREHGCLRVDDIDVPSSDFIVFGAGPSLRSHLKRFRALDEPMTVISADGATTALLEEDVLPDIIVTDLDGKMEDIIEANRQGAVVVVHAHGNNLPALRRYLPLLQNIIGTTQSIPHGCLHNFGGFTDGDRAVFLAAALGAGRIVLAGMDFGEVVTRYSRPDMDSELGPADPVKRLKLEYASRLIDWLERNGDVRIERW

mptE

6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

231 amino acids

Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP). To a lesser extent, can also use CTP, UTP, and GTP as the nucleotide triphosphate substrate.

Belongs to the archaeal 6-HMPDK family.

26.262 kDa

MKWEEWKPFYERIVKEMGYSIEEDRRAAELLRDILMENDNYIIKEELNSIIMQKVYVFGAGPNLEEALKKGDFKDGTKIAADGATSALLEYGITPDVVVTDLDGRIRDLLEASRKAVMVVHAHGDNMDKLPLVVEFPLVLGTCQTEPLDIVYNFGGFTDGDRAAFLAEEMGAKEIVLVGFDFSGIVGKWSKPWLRDHTPAWESKMKKLKFARELLEWLKNNGRAKIIEFSI