mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

391 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.48 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHAAGYEVVFIDVMDSVINSLQQTPSYDVTEVSEEGESTKTITNYRAINSKTHEADVVQEIASADVVTCAVGPNILKFIAPVIAKGIDARTEERPVAVIACENAIGATDTLHGYIKQHTNPDRLETLSERARFANSAIDRIVPNQPPNSGLNVRIEKFYEWAVEKTPFGEWGHPDIPAIHWVDHLEPYIERKLFTVNTGHATTAYYAHKRGKKMIAEALEDPEIRETVHKVLEETASLIVSKHEISEQEQKEYVDKIVSRISNPYLEDNVERVGRAPLRKLSRKERFIGPASQLAERGQKFDALLGAIEMALRFQNVPGDEESSELARILKENSAEDATSQLTGLEKDHPLYSHVVERVSTVQQGSKSVL

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

42.661 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFVDVMDKIIDALTSNPSYQVTEVSDEGERTKTITNYSAINSKTHESEVVQEIATADVVTCAVGPNILKFIAPVIAKGIDARTASKPLAVIACENAIGATDTLHGFIKQNTDESRLSTMGERAQFANSAIDRIVPNQPAGEGLNVRIEKFYEWVVEKTPFGSVGHPDIPAIHWVDHLEPYIERKLFTVNTGHATTAYYGYQRGKKMIAEALADPEIRQIVHQVLEETASLIVAKHEISEEEQKEYVNTIISRISNPYLEDNVERVGRAPLRKLSRKERFIGPAAQLAEKGMKYDALLGSVEMALRFQNVPGDEESVELAKILNEMSADDATAKLTGLEKSHPLYQPVQNVVAKVQKGGK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.004 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFIDVVDKIIDALKSTPSYEVTEVSEEGEKTKTITNYRAINSKTNEEDVVKEIGTADVVTCAVGPNVLKFIAPVIAKGIDARTASKPVAVIACENAIGATDTLRGFIEQNTDKDRLSSMSERARFANSAIDRIVPNQPPNAGLNVRIEKFYEWTVEQTPFGEFGHPDIPAIHWVDDLKPYIERKLFTVNTGHATTAYYGHMRGKKMIADALADAEIRQIVHKVLEQTAKLITTKHEITEQEQNEYVDTIVKRMSNPFLEDNVERVGRAPLRKLSRNERFIGPASQLAEKGLPFDALLGSIEMALRFQNVPGDEESAELAKILKEMSAEEATGKLTGLEKHHPLYEPVQNVIAKVQKDSK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway. Has a strong preference for NADH over NADPH.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.004 kDa

Sequence

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Aspergillus niger (strain CBS 513.88 / FGSC A1513)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the metabolism of mannitol. Has a strong preference for NADH over NADPH (By similarity).

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.231 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHKAGYEVVFVDVMDKMVEALQQNKSYKVTEVSEEGEHTTTITNYRAINSKTHESDVIQEIATADVVTCAVGPNILKFIAPVIAKGIDARTESKPVAVIACENAIGATDTLHGFIKQHTSQDRVESLYDRAQFANSAIDRIVPQQAPNSGLDVRIEKFYEWAVEKTPFGSVGHPDIPAIHWVDNLEPYIERKLFTVNTSHATTAYFGHFRGKKMIADALEDKEIRGLVHKVLEETASLIVAKHDISEEEQKEYVEKIVSRISNPYLEDNVDRVGRAPLRKLSRKERFIGPASQLAERGMKYDSLMDAVEMALRFQNVPGDDESAELANILQEQPAEDATTNLTGLEKEHPLYPAVLDRVRKVQQGTK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Aspergillus niger

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway. Has a strong preference for NADH over NADPH. Required for protection of conidiospores against exogenous stresses such as high temperatures and an oxidative environment.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.363 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHKAGYEVVFVDVMDKMVEALQQNKSYKVTEVSEEGEHTTTITNYRAINSKTHESDVIQEIATADVVTCAVGPHILKFIAPVIAKGIDARTESKPVAVIACENAIGATDTLHGFIKQHTSQDRVESLYDRAQFANSAIDRIVPQQAPNSGLDVRIEKFYEWAVEKTPFGSVGHPDIPAIHWVDNLEPYIERKLFTVNTSHATTAYFGHFRGKKMIADALEDEEIRGLVHKVLEETASLIVAKHDISEEEQKEYVKKIVSRISNPYLEDKVERVGRAPLRKLSRKERFIGPASQLAERGMKYDSLMDAVEMALRFQNVPGDDESAELANILNEQRAEDATIHLTGLDEEHPLYPAVLERVRKVQQGTK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

42.864 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFVDVMDAVVSALQTTPSYNVTEVSKDGENTKTISNYRAINSKTNESDAVKEIATADVVTCAVGPNILKFIAPLIAKGIDARTESKPVAVIACENAIGATDTLHGFIKEHTPKDRLDTLYDRARFANSAIDRIVPNQPPNSGLNVRIEKFYEWAVEQTPFGSFGHPDIPAIHWVDNLEPYIERKLFTVNTGHATTAYYGHLRGKKMIADALADDEIRSMVHKVLDETASLIVSKHGIPEDEQKEYVDTIIGRMSNPYLEDNIERVGRAPLRKLSRKERFIGPASQLAERGQKFDALVDAIEMALRFQNVPGDQESADLAQILKQKSSEDATSELTGLEKDHPLYSPVLERVAKVQQDTK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)

Length

388 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

42.891 kDa

Sequence

MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFIDVVDKIIDALKSTPSYEVSEVSEEGEKTKTITNYRAINSKTNEEDVVKEIGTADVVTCAVGPNVLKFIAPVIAKGIDARTASKPVAVIACENAIGATDTLRGFIEQHTDKDRLSSMSERARFANSAIDRIVPNQPPNAGLNVRIEKFYEWTVEQTPFGEFGHPDIPAIHWVDDLKPYIERKLFTVNTGHATTAYYGHVRGKKMIADALADAEIRKIVHNVLEQTAMLITTKHEITEQEQNEYVDTIVKRMSNPFLEDNVERVGRAPLRKLSRNERFIGPASQLAEKGLPFDALLGSIEMALRFQNVPGDEESAELAKILKEMSADEATGKLTGLEKSHPLYKPVQNVVAKVQKDSK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA

Gene

mpdA

Protein

Mannitol-1-phosphate 5-dehydrogenase

Organism

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

Length

386 amino acids

Function

Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.

Similarity

Belongs to the mannitol dehydrogenase family.

Mass

43.102 kDa

Sequence

MGKAIHFGGGNIGRGFVGEFLHEAGYEVVFVDVVDDLITSIQNTPSYEITEISEDGEKTKKITNYRALNSKSHEADVVQEIATADIVTCAVGPRVLQFIAPVIAKGLESRNVSTPLTVIACENAINATDTLRGHIEKKTKPEIISERAVFANCAIDRIVPNQPPNNGLNVRIEKYWEWVVEQTPFKEKGVAHPNVSAIHWVDKLDPYIERKLFTVNTGHATTAYYGHLAGKKTIADALHDPKIRENVHKVLDETASLIINKHGISEQEQKEYVDKIISRISNPYLEDGVERVGRAPLRKLSRNERFIGPASQLAERGLKFDALLGAIEQALRFQNVEGDEESKELAKILKEKTAEEATSELTELEKDHPLYSHVLERVRTVQQESK

Protein

Mannitol-1-phosphate 5-dehydrogenase: mpdA