moody

G-protein coupled receptor moody

675 amino acids

Required in glia to regulate the acute sensitivity to cocaine and to continuously maintain the proper blood-brain barrier (BBB) function. A moody-mediated signaling pathway functions in glia to regulate nervous system insulation and drug-related behaviors (By similarity).

Belongs to the G-protein coupled receptor 1 family.

72.863 kDa

MSDETTGSLGDAFSPMDTPTTTIMPPPADVDESGFSHSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQGTWRHGEVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHYSLYNRIYKRHWIAIMIAACWLFSYGMQLPTLLGAWGRFGYDARLQTCSIMSDRHGHSSKTTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLAAATSMPSGDGANPSQVPAGCRVSSDSSSNYSTDVPDTTPGGAGGGAGVKQQPSRVKDQREVRAKRNEWRITKMVLAIFLSFVICYLPITIVKVADKDVEHPSLHIFSYIMLYLSACINPIIYVIMNKQYRKAYKTVVFCQPAARLLMPFGKGNGASSAAEKWKDTGLSNNHSRTIVSQMSAGATATATATAAAGTQPQSTSTQGPVQALELTARVPDLISKSSNLPLPQPLPQIPPAGARPSLTPPPPPSVLTATHSNGSGSQRLPLKKNNHSYTNSGFNSSVISANPSSSPSPSSSGGGIYRPGIGSMGNGSASIRRITMVGDDIILEEEELPPTPTASSPPQMQAPPPPPSSSRQTTMNALNTTPKTPIYMNVDSPKRNQSYSERNIPVPAREGHDQGVKDSQGLPSKLMDKKKFPKD

moody

G-protein coupled receptor moody

670 amino acids

Isoform A and isoform B are required in glia to regulate the acute sensitivity to cocaine and to continuously maintain the proper blood-brain barrier (BBB) function. A moody-mediated signaling pathway functions in glia to regulate nervous system insulation and drug-related behaviors. Galphai and Galphao, and the regulator of G protein signaling, loco, are required in the surface glia to achieve effective insulation. The components function by regulating the cortical actin and thereby stabilizing the extended morphology of the surface glia, which in turn is necessary for the formation of septate junctions of sufficient length to achieve proper sealing of the nerve cord.

Belongs to the G-protein coupled receptor 1 family.

71.932 kDa

MSDETTISLEDGYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHHGLYARIYKRHWIAVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTDDHGHSSKTTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADKNVEHPSLHICSYILLYLSACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEKWKDTGLSNNHSRTIVSQMSGGTGAASGAGTATGTAAVAVMQTPPEVQQAQALEMVSRGPDLISKSNLPQPNVTPPPPSVLTATPNGSNSNSLTLRLPLKKNNHCYTNSGFNSSTPSPSSGLGIGISSSSIYRPGVGSLGSGSASIRRITMVGDDIILEEEELPPTPPATSAPTTPAPPPPSSPLHPLSTDSSTTTISGGAVVAGSSAPKPATPTPHIYMNVDSPKRNQYYMDRNTNAVAPESDSGPANTSATVSISGSKLTAKMKFPKD