Protein
GrpE protein homolog, mitochondrial
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Sequence
MRPSTRFLRSVTRTVPIGFRSTTVPFVSSTLRSSAATSNQFSARFSGVRFYADEAKKEEPKDENDAAAAEEDANLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN