About Products Protein Database Contact

mge1

Gene
Mge1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Arabidopsis thaliana
Length
302 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). Binds ATP (PubMed:17137349). Interacts with copper ions Cu(2+) (PubMed:20018591).
Similarity
Belongs to the GrpE family.
Mass
33.203 kDa
Sequence
MLVSRVLSRVSRSAGLRSSFSSVVTPKRNQIPIVASRFHSLVHGTPNKLVAVPVSLRNHGTLDLNVLQRFGFFSSSSAEPKGNESNTEVPKTGETSENVEVGKATDAEIDFDDLSRDDLVKLVSEKEDLLKVQQKDIMEMKDKFLRTYAEQQNLMDRTNRNAESAKKFAVQNFATSLLDVADNLERASSVVKESFSKIDTSKDLAGATPLLKNLLEGVEMTEKQLAEVFRKAGLVKEDPLNEPFNPNRHNAVFQVPDASKPKGTIAHVLKSGYSLYDRVIRPAEVGVTCAVENQEGGKESAA

Gene
mge1
Protein
GrpE protein homolog, mitochondrial
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
243 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
27.529 kDa
Sequence
MRPSTRFLRSVTRTVPIGFRSTTVPFVSSTLRSSAATSNQFSARFSGVRFYADEAKKEEPKDENDAAAAEEDANLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN

Gene
mge1
Protein
GrpE protein homolog, mitochondrial
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
243 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
27.231 kDa
Sequence
MQRALLSSLRRSAGIRSGVNSMRVVRPTVLAPRMSMIRFASTEASKKEGKEDKAEAQGSQEPETAAETNKEAEGAKVEVSEIDELKAKLTKKDRELADMKNHYARAIADFRNLQESTKLEKQKARDFALQKFAKDLLESVDNFDLALNAVKEDTLKNNSEVKNLYDGVDMTRNVFEKTLARHGIEKVDPIGEQFDPNQHEATFEIAQPDKEPGTVFHVQQNGYTLNSRVLRPAKVGVVKDAEN

Gene
mge1
Protein
GrpE protein homolog, mitochondrial
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
231 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
26.299 kDa
Sequence
MRAFSNVSRISRVSRVSRVALAAPARTVPLMNRNAMSMMRFYSEDAKASEKAGEKAEEKAEEQNLSAEEQKLKDLQEQLDKKTKEAAELKDRLLRSVADFRNLQEVTKKDVEKAKSYALQKFAKDLLESVDNFGHALGAFKEEDLEKSKEISDLYTGVKMTRDVFEKTLKKYGIEKLDPLGERFDPNKHEATFELAQPDKEPGTVFHVQQLGYTLNERVIRPAKVGVVKED

Gene
MGE1
Protein
GrpE protein homolog, mitochondrial
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
228 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins and the association of SSC1 with TIM44.
Similarity
Belongs to the GrpE family.
Mass
26.066 kDa
Sequence
MRAFSAATVRATTRKSFIPMAPRTPFVTPSFTKNVGSMRRMRFYSDEAKSEESKENNEDLTEEQSEIKKLESQLSAKTKEASELKDRLLRSVADFRNLQQVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKEEDLQKSKEISDLYTGVRMTRDVFENTLRKHGIEKLDPLGEPFDPNKHEATFELPQPDKEPGTVFHVQQLGFTLNDRVIRPAKVGIVKGEEN

Gene
mge1
Protein
GrpE protein homolog, mitochondrial
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
223 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of ssc1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
25.334 kDa
Sequence
MLGLGRVFSSAVRPRTLIRAPINKRSFLWYSTEAAKEEKPAEEKVAETENVDVKELQSKLSELKSKYEAKDKEVAELKGSIRQSLADYRNLENRMKRDMEQTRAFAVQKLTKDLLDSVDNLERALSIVPEEKRNNRESNKDLVDLYEGLAMTESNLMKTLGKYGLVRYDGIGEDFDPNIHEAVFQIPVEGKKPNTVFHCESKGFQLNGRVIRPAKVGVVKGDD

Gene
mge1
Protein
GrpE protein homolog, mitochondrial
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
212 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
23.297 kDa
Sequence
MGPYLPAILRPIGRYATLYNVPRVAGQLRCYAADAKDAADAQGESAADPRVAELEKQLADKSKEAADLKDRLLRSVADFRNLQEVTRRDVQKARDFALQRFSKDLLESLDNFGHALGAVSPEALQRSPEIADLHAGVRLTRDVFEKTLLKHGIAPIDALGQPFDPNLHEATFELPQPDKTPGTVFHVQQPGYTLNGRVIRPAKVGVVKDPDA