mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)

Length

398 amino acids

Function

Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.761 kDa

Sequence

MNEQGLSEREIFSYLENAKSEDTDYYRVFSSMCTRPHKIAIEANRLFIEANLGDLGLFAGAHKLEQEVVRMLGNLLHASSIDVPSGGLCQSSVCGYLTTGGTESNIQAVRGMKNLVTAGKKEFKGTPNIVIPASAHFSFDKVADMMGIEVRRASLDSEFRVDMASVEKLINENTIGLVGIAGNTEFGQIDPIDKLSEVALENELFLHVDAAFGGFVIPFLEKPQPFDFKVPGVTSIAIDPHKMGLSTIPSGALLFRSPSFLDSLKVSTPYLTTKSQFTLTGTRSGASAAATCAVMKYLGYEGYRKNVQYCMELTSKIVEEARKLGFEPLIEPVMNVVALKVPNPDLVRERLLKKFGWNVSITRTPRALRLVLMPHNSPEDIELFLEDLKKVTAEIKSP

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

L-tyrosine/L-aspartate decarboxylase

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Length

396 amino acids

Function

Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis (PubMed:15715981). Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis (PubMed:24891443).

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

45.05 kDa

Sequence

MRNMQEKGVSEKEILEELKKYRSLDLKYEDGNIFGSMCSNVLPITRKIVDIFLETNLGDPGLFKGTKLLEEKAVALLGSLLNNKDAYGHIVSGGTEANLMALRCIKNIWREKRRKGLSKNEHPKIIVPITAHFSFEKGREMMDLEYIYAPIKEDYTIDEKFVKDAVEDYDVDGIIGIAGTTELGTIDNIEELSKIAKENNIYIHVDAAFGGLVIPFLDDKYKKKGVNYKFDFSLGVDSITIDPHKMGHCPIPSGGILFKDIGYKRYLDVDAPYLTETRQATILGTRVGFGGACTYAVLRYLGREGQRKIVNECMENTLYLYKKLKENNFKPVIEPILNIVAIEDEDYKEVCKKLRDRGIYVSVCNCVKALRIVVMPHIKREHIDNFIEILNSIKRD

Protein

L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

Length

395 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.305 kDa

Sequence

MNEQGLSEKEIFSYLENAKSEDTDYYRVLSSMCTHPHKIAVEANRLFIEANLGDLGLFAGASRLEQEVVGMLGELLHAPSIDVPFGGSCESSACGYLTTGGTESNIQAVRGMKNLVTTGKKELKGAPNIVIPESAHFSFDKVADMMGIEVRRASLDSEFRVDMASIESLIDANTIGLIGIAGNTEFGQIDPIDKLSEIALENELFLHIDAAFGGFVIPFLEKPQPFDFKLPGVTSIAVDPHKMGLSTIPSGALLFRSASFLDSLKVNTPYLTTKAQFTLTGTRSGASAAATCAVMKYLGNEGYRKNVQYCMQLTEKLVIEARKIGFEPLLEPVMNVVALKVPNPDFVREQMLERFGWNVSITRTPRALRLVLMPHNTLEDIEIFVQDLKEVTVEI

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanosarcina barkeri (strain Fusaro / DSM 804)

Length

395 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.889 kDa

Sequence

MNEQGLSEKEIFSYLEDVKSEDTDYYRVLSSMCTHPHRIAVEAHRLFIEANLGDLGLFAGAHRLEKEVIRMLGELLHAQSVEIPSGEACESSVCGYLTTGGTESNIQAIRGMKNLVTEDGKKSGEILNIVVPESAHFSFDKVANMMGIEVKRASLDPEFRVDIASAESLIDANTIGLVGIAGNTEFGQVDPIEELSKLALENELFLHVDAAFGGFVIPFLEKPYSFDFKVPGVTSIAIDPHKMGLSTIPSGALLFRSPFFMDSLKVNTPYLTTKSQFTLTGTRSGASAAATYAVMKYLGREGYRKNVQYCMQLTTKLVKEARKFGFEPLIEPVMNVVDLRVPNPDIVREQLLKKFGWNVSITRNPRSLRLVLMPHNTARDIEEFLQDLRKVTTEL

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)

Length

390 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.926 kDa

Sequence

MDERAVLEELKKYRKMDLKYEDGAILGSMCTKPHPITKKISDMFFETNLGDPGLFRGTKKLEDEVINNIGKFLNNPNPFGYIISGGTEANITAMRAINNIAKAKRKNHKTTVIMPETAHFSFEKAREMMDLNLITPPLTKYYTMDLKYINDFIEDRNNKNDISVDGIVGIAGCTELGAIDNIKELSKIAEQNNIFLHVDAAFGGFVIPFLDDKYKLDNYCYEFDFSLNGVKSMTVDPHKMGLAPIPAGGILFRDKSFKKYLDVEAPYLTDIHQATIIGTRSGVGVASTWGVMKLFGEEGYKNLASECMDKTHYLVKEAKKLGFKPVIDPVLNIVALEDDNPEETSLKLRKMGWFISICKCVKALRIIVMPHVEKEHIDKFLGALTEVKKN

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)

Length

389 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.719 kDa

Sequence

MFDKGRSKEDVFRDLNVFHNMDMKYSSGRILGSMCTKPDPVGLEAYKMFIETNLGDPGLFKGTALMEQEVINSLGNLLHLKNPCGHIVTGGTEANIMAMCVAKYLYEEENEGTPELILPKSAHFSFKKVLSMLSVKPVYVPLNNEYKIDVTKLPDLITDNTMAMVGIAGTTELGLVDDIPEISKIAKSYGVYLHVDAALGGFIIPFLNYKNNNQLNFDFKCKGVSSITIDPHKMGLAPVPSGGIIFRKKKYLEKLSIKTPYLTKDKQTTIVGTRTGASTAATWTLLNYHGMEGYKKIVEKVINLTTYTYNKLNKNKHVTIIHKPELNIISFKVDNIDVDTLQKQLQAYGWIVSLAEYPHVIRLVLMPHIKKEHIDEFLVDLDIIIQKNR

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)

Length

385 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.725 kDa

Sequence

MEDKPISKKDILKELNEIQSKDHKYSDGRILGSMCTEAHPFAKEVYCKFLDSNLGDPGLFKGTKYIENEVIKSIGELLSISEPYGNIVTGGTEANIMAMRAARNHARKYKGIKEGEIIIPDSAHFSFKKAADMMNLKIIEAKLDENYKIDVDSVKENISDNTVAIVAIAGTTELGLVDPIEELSEIAYENNIYFHVDAAFGGFSIPFLRKIGYEFPPFDFSLPGVCSITVDPHKMGLAPIPAGGILFRKKEYLEVMAVDSPYLTVKTQSTIVGTRSGAASAATYAIMKYLGNEGYEKLAGNLMDNTHYFKEGLEKIGYDVVVEPELNIVAFNHPDMEAHDLADKLEDLGWRVSVAKCPIAIRVVLMNHITKQHLTDLLDDLTEIY

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333)

Length

384 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.335 kDa

Sequence

MEEQDILNELRKYRSQDLKYEEGYILGSMCTKPHPIARKISEMFFETNLGDPGLFNGTSKLEKEVVSMLGSILHNNNAFGYIISGGTEANLTAMRAFKNISKSKDKKQNIIIPETAHFSFDKARDMMDLNVVRPPLTEYFTMDVKFIRDYVEDSKNEISGIVGIAGCTELGSIDNIYELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLKGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFRDNTFKKYLDVDAPYLTEKQQATLIGTRSGVGVASTWGIMKLLGIEGYENLVNESMEKTKHLVKKAREYGFETAIDPVMNIVALKDENKQDTCMKLREENWYVSVCRCVEALRIVVMPHLEIEHIDGFLESLSNTKKY

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331)

Length

384 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.32 kDa

Sequence

MDEQDILKELRKYRSQDLKYEEGYILGSMCTKPHPMARKISEMFFETNLGDPGLFKGTSKLEKEVVSMLGGILHNNNAFGYIISGGTEANLTAMRAFKNISKSKDKQQNIIIPETAHFSFDKARDMMDLNVVRPPLTEYFTMDVKFIRDYIEDSKNEISGIVGIAGCTELGSIDNIYELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLKGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFKNNTFKNYLDVDAPYLTEKQQATLIGTRSGVGVASTWGIMKLLGIDGYKKLVNESMEKTMHLVKKAREYGFETAIDPVMNIVALKDEDKHDTCMKLREENWYVSVCRCVEALRIVVMPHLEIEHIDGFLESLSNTKKY

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcus maripaludis (strain S2 / LL)

Length

384 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.145 kDa

Sequence

MDEQDILNELREYRNQDLKYEEGYILGSMCTKPHPMARKISEMFFETNLGDPGLFKGTSKLEKEVVSMIGGILHNKNAFGYLISGGTEANLTAMRAFKNISKSKGKPQNIIIPETAHFSFDKAKDMMDLNVVRPPLTKYFTMDVKFIKDYIEDSKNEVSGIVGIAGCTELGSIDNICELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLDGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFRDNMFKKYLDVDAPYLTEKQQATIIGTRSGVGVASTWGIMKLLGIDGYETLVNESMEKTMYLVKKAREYGFETAIDPVMNIVALNDENKHDTCMKLRDENWYVSVCRCVDALRIVVMPHLEIEHIDGFLESLSNTKKY

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)

Length

384 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

43.124 kDa

Sequence

MDELSILNELRKYRDMDLDYEDGTILGSMCTKPHPLTRKISEMFFETNLGDPGLFKGTRELEKQAISMIGNVLGNKDAFGYIISGGTEANLTAMRAFKNVSKKSGKSLNIIIPETAHFSFDKAKDIMDLNVIRPPLTKYFTMDVKFIRDYVFDNPNKISGIVGISGCTELGSIDNIAELSKIAVDNDILLHVDAAFGGFVIPFLYDKYKLKNYRYEFDFSLEGVSSITIDPHKMGLAPISAGGILFRNNSFKKYLDVDSPYLTEKQQATLIGTRSGVGAAATWGVMKLLGTSGYKKIVNDSMEKTYYLTRKLREYGFKTAIDPVINIVSIVDEHKNETCAKLRENGFHVSVSRCVDALRIVIMPHIEFEHIDIFLDCLSNTKRY

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Pyrococcus abyssi (strain GE5 / Orsay)

Length

384 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.887 kDa

Sequence

MSKFPEKGLPREEVLNLLEDKTKVDLTFSSGKILGSMCTMPHELAIEVFARYIDRNLGDPGLHPGTRKIEEEVIEMLSDLLHLEKGYGHIVSGGTEANILAVRAFRNISDAERPELILPKSAHFSFIKAGEMLGVKLVWAELKQDYAVDVKDVEAKISDNTIGIVGIAGTTGLGVVDDIPALSDLAREYGIPLHVDAAFGGFVIPFAKSLGYDLPDFDFKLKGVESITIDPHKMGMAPIPAGGIIFRRKKYLKAISVLAPYLAGGKVWQATITGTRPGASVLAVWALIKHLGFEGYREIVRKAMELSRWFAEEIKKLNNAWLVREPMLNIVSFQTKNLRKVERELKRRGWGISAHRGYIRIVFMPHVTKEMVEEFLRDLREVLK

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

L-aspartate decarboxylase

Organism

Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

Length

384 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine. In vitro, can also catalyzes the decarboxylation of L-glutamate to produce 4-aminobutanoate, but this activity does not seem necessary in vivo. Shows much higher activity with L-aspartate than with L-glutamate. Does not decarboxylate L-tyrosine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.545 kDa

Sequence

MFPERGASEEEVLRELEEKTREDLTFDSGKILGSMCTYPHPFAVKVVMKYIDRNLGDPGLHIGSQKIEKEAVDMLANLLGLEKGYGHIVSGGTEANILAVRAMRNLAGIEKPELILPESAHFSFIKAAEMLGVKLVWAELNDDYTVNVKDVEKKITDRTIGIVGIAGTTGLGVVDDIPALSDLALDYGLPLHVDAAFGGFVIPFAKALGYEIPDFDFRLKGVKSITIDPHKMGMVPIPAGGIIFREKKFLDSISVLAPYLAGGKIWQATITGTRPGANALAVWAMIKHLGFDGYKEVVKEKMELARWFASELKKIPGIYLIREPVLNIVSFGSEKLEELEKELKARGWGVSAHRGYIRIVVMPHVKREHLEEFLRDLREIAKRL

Protein

L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)

Length

383 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.137 kDa

Sequence

MYTFPEKGLSEDMVTDLLKEMRSRDCPYDRLLSTMCTRPHPVAVRAYSMFLETNLGDPGLFPGTAEIERRVVGILGSLLGCSDATGYVSTGGTESNIQAVRAARNSSGRRDGNIVVPRSAHFSFDKIADLLNLEVRKAELDESLRVDVGDVERLIDDRTVCLVGIAGTTEFGQVDPIGDLSELAIENGIPLHVDAAFGGFVLPFLEKDCMWDFRAEGVQSITIDPHKMGMSPIPAGGLIFRSSDPLRRLETETYYLTVSRQASLTGTRSGAAAAATYAVIMHLGIDGYRKVVRRCMDMTEHLVSEARAMGIEPVIEPVMNVVALRVDDPPGVRRALLERGWHVSMTREPKALRLILMPHMTDENLDLFLSDLEDVLISLRRGG

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

L-aspartate/L-glutamate decarboxylase

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

Length

383 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine, and the decarboxylation of L-glutamate to produce 4-aminobutanoate. Can also use cysteate and cysteine sulfite, but not L-tyrosine. Specific activities toward L-aspartate and cysteate are higher than toward L-glutamate.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.694 kDa

Sequence

MKFPRIGLPKEKVIELINEKTKKDLTFSSGKILGSMCTMPHDLAIEVYTKYIDRNLGDPGLHPGTRKIEEEVIEMISDLLHLEKGHGHIVSGGTEANILAVRAFRNLSDVEKPELILPKSAHFSFIKAGEMLGVKLVWAELNPDYTVDVRDVEAKISDNTIGIVGIAGTTGLGVVDDIPALSDLARDYGIPLHVDAAFGGFVIPFAKELGYELPDFDFKLKGVQSITIDPHKMGMAPIPAGGIVFRRKKYLKAISVLAPYLAGGKVWQATITGTRPGASVIAVWALIKHLGFEGYMRIVERAMKLSRWFAEEIKKINNAWLVREPMLNIVSFQTKNLKKVERELKSRGWGISAHRGYIRIVFMPHVTREMIEEFLKDLKEVLS

Protein

L-aspartate/L-glutamate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)

Length

383 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.646 kDa

Sequence

MFPERGTDEEEVLEELRRKTREDLTFDSGKILGSMCTYPHPFAVKIITEFIDRNLGDPGLHIGSRKVEEEAVEMLSNLLGLKKGYGHIVSGGTEANILAVRAFRNLAGVEKPELILPKSAHFSFIKAGEMLGVKLIWAELNEDYTVNVRDVEEKITDNTIGIVGIAGTTGLGVVDDIPALSDLALDYGLPLHVDAAFGGFVIPFAKALGYDIPDFDFRLKGVKSITIDPHKMGMVPIPAGGIIFRERKYIDAISILAPYLAGGRIWQATITGTRPGANALAVWAMIKHLGFEGYKEIVRKAMELSQWFAGELKKIPGVYLIREPVLNIVSFGTENLERVEEELKRRGWGISAHRGYIRIVMMPHVRREHLEEFLRDLEEIVRG

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)

Length

379 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

42.116 kDa

Sequence

MEENGKTKEEILLFLKKAKSADASYERVLSSMCTYPHEIAVLAHTQFIESNMGDPGLFPGTFNLEKQVLAMFGKMLHHKNSPEKAGYLTTGGTESNIQAIRSMHNFRHDISRPNIVMPESAHFSFDKVANLSGIEIRKASLDKLLKVDLDSVRSLIDKNTIGLVGIAGTTEFGQLDPINELSKIAIEKGIFLHIDAAFGGFVIPFMDIDYTYDFRLEGVTSMTIDPHKMALSTIPSGGLLFKEPEYFECLEIHTPYLSVNKQYSLTGTRSGAGVASTYAVMKHLGRKGYKKVVSDCMSVTKKLVDGAEKLGINTVIDPVLNIVALDVPEADLVRKKLLDEYGWHVSITRNPRALRIVIMPHIKNETIELFLKDLAKVIK

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)

Length

375 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

41.138 kDa

Sequence

MRERGLGEEEIFAELCEARSRDVPYGRVLSSMCTNPHPIAVKAHQEFVNTNLGDPKLFPGTADIEHRCIGLIGDLLHLPAATGYISTGGTESNIQALRTAIQMKHTDRRRANIVVPESAHYSFEKASQMLGIAIRRAPLDDLLRADPSEMAALIDKNTIALVAVAGTTEFGQIDPIEEIGRLAQEHDLYLHVDAAFGGFVIPFMDRPAKFDFEIPGVQSITIDPHKMGLSTIPSGGLLYRSESLMKVLEINAQYLTSMVQTSLAGTRSGASAASAYAVLQYLGRAGYREIVATCMENTRILREQLEDMGMEPIIEPVLNIVTARAKDPVGLRKKLAEKNWYVSTTVHPCALRMVVMPHVTADVIEAFTADLKKVI

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)

Length

372 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

40.407 kDa

Sequence

MILQRDSDYSDGTVLGSMCTEPHPVAAEAFVAGLHVNLGDPYLFPNAYRAERECIGWLAETLLDHPAPEEAEGSIVSGGTEANILAAYAAREVTGGREIIVPATRHFSFEKAARMLRMKLVEAPLRSDYTVDVDAVQDLISRDTALIVGIVGTTETGSVDDIEALSDVAEDHGVPLHVDAAFGGFTAPFLREEYPLPRFGFDLEAVVSVTVDPHKMGLVPPPAGGIVFRDDEFPKAIEVYAPYLSGGGASQYTITGTRPGAPVLALYANILELGEEGYRRIAFRCYEETLKVAEKARELGLELAVDPPHLNLVNIRLPDRGTAERLLRESEREGWKISVSTKPLGVRIVMMPHLDAETVSRFLELVARVLGG

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Length

371 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

40.996 kDa

Sequence

MKFPRKGIPQEEVMRELEKYTSKDLSFSSGKILGSMCTLPHELAKEVFCMYMDRNLGDPGLHPGTKKIEEEVIEMLSDLLHLERGYGHIVSGGTEANILAVRAFRNLADVENPELILPKSAHFSFIKAGEMLGVKLIWADLNPDYTVDVKDVEAKISENTIGIVGIAGTTGLGVVDDIPALSDLARDYGIPLHVDAAFGGFVIPFAKELGYDLPDFDFKLKGVQSITIDPHKMGMAPIPAGGIVFRHKKYLRAISVLAPYLAGGKIWQATITGTRPGASVLAVWALIKHLGFEGYMEIVDRAMKLSRWFAEEIKKTPGAWLVREPMLNIVSFKTKNLRRVERELKSRGWGISAHRGYIRIVSHASCDGGHD

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)

Length

369 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

40.25 kDa

Sequence

MDAEGLSTDELFCFLQAKRNEDFSYSHILSSMCTTPHPVAVQAHNLFMETNLGDPGLFPGTATLEDRLIRWFADLYHEPSAGGCTTSGGTESNIQVLRFCKKTKNVKEPNIIVPASAHFSFEKACGMMDIEMRVVPVDEQYRMKTDAAGELIDKNTCCIVGVAGTTEYGMTDPIPALGKLAEQEGVHLHVDAAFGGYVLPFLDDAPPFDFSVPGVGSIAVDPHKMGLSTIPSGVLMVRDERVFCNLLVETPYLTTKQAYSLTGTRPGASVAAAYAVMAYLGRKGMKALVTGCMENTRRMIEGMEAFGVHRKVTPDVNVATFEHVSVPSPWVVSYTRKGDLRIVCMPHVTRDVVEAFLSDFGESYVSHIS

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Length

367 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

41.171 kDa

Sequence

MDIIEELRAYREKDIPYSRVLSSMCTVPHPVAVEAHRMFIETNLGDPGIFRGTVELEAKLMRLIGDILHCETPAGYICSGGTEANIQGIRAARNVQKKENPNIVIPKTAHFSFEKIGDILGVKIKRAGVDEEYKVDVGQVEDLMDENTVAIVGIAGTTELGQIDPIVELSKLAEERQVELHVDAAFGGLVIPFMDNPYPFDFQNRGVSSITIDPHKMGMATIPAGGIIFRNESYLRALEVETPYLTSKTQFTLTGTRPGTGVASAYAVLKSLGFEGMREVVKNCLKNTRILVEEMRDLGFEPVIEPVMNVVSFRTDEAERIKEELYRMRWVISTIREPKAIRFVVMPHVTEEVIKNFISDFRKVLRR

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)

Length

365 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

39.263 kDa

Sequence

MLSNGISEDDLFSFLSLHKKEDLDHRYILSSMCTLPHPVAVRAHCMFMETNLGDPGLFPGTAALERLLVERLGTLFHHKNAGGYATSGGTESNIQALRLAKALRPGSSPNVVLPESVHFSFKKACDLLSLEMRSVPLGTDRRIMADKAAELIDKNTICLVGVAGTTEYGMVDPIADLAKIAAQQDIFLHVDAAFGGMVIPFLPKPVPFDFALPGVTTLAVDPHKMGMSTIPAGVLLTREPDMLDALNIDTPYLTVKKGYTLGGTRPGAPMAGALAVLDYLGISGMKAVVAGCMKNTERLIAGMETRGIQPAASPDVNVATFVCDRVPEPWKVSWTRAGHLRIVCMPHVTADRIEAFLSDFGDMYA

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)

Length

365 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

39.705 kDa

Sequence

MEEKGCKREEVISLLSAYRAEDLHHDHILSSMCTIPHEMAVFVHGMFSATNLGDPGLFPGTTKIEDRLVHSLGELMHHPGAGGYATSGGTESNLQAIRIAKKLKPEIKNPNIVVPASAHFSFDKTCDILGLEMRTVPYGKNYTVDCDKMAEMVDKNTISVSAIAGTTEYGMIDDVERIAKIALENDLFFHVDAAFGGMVIPFLPNPAPFDFEVPGVSSISLDPHKMGMSTIPCGCLLLREPEQFGTLNVDTPYLTVKKECTLAGTRPGADVAGAYAVIKLLGREGFRAVVAGCMENTRRLIEGMEAFGYTRAVDPVMNVATFEAGPVPKGWIVSHTRAGHLRFVVMPHVTRDVIENFLADVAKIN

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)

Length

365 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

39.401 kDa

Sequence

MREVGCPEEDLFSFLSSKRREDLGYRNILSSMCTPPHPVAARAHAMFLETNLGDPGLFPGTAALEDLLVRRLGTLMHLPDAGGYATSGGTESNIQAFRIAKKLKSAKSPNVVVPASSHFSFTKACDILGLEMRTVPLDAGFRMETEAVDGLIDHNTVALVGVVGTTEYGMVDPISRLSEIALDRNVFLHVDAAFGGMVVPFLDRPVPFDFSLPGVSSISVDPHKMGMSTIPAGCLLTRSAEWFSCLNVDTPYLTVKRECTLAGTRPGASVAAAIAVLEYLGMDGMRAVVAGCMENCRRLIEGMETLGYPRAVTPDVNVATFSCERAPVGWRVSTTRNGHMRIVCMPHVTRDVVEQFLVDMGDTDA

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)

Length

363 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

39.265 kDa

Sequence

MLNKGLAEEELFSFLSKKREEDLCHSHILSSMCTVPHPIAVKAHLMFMETNLGDPGLFPGTASLERLLIERLGDLFHHREAGGYATSGGTESNIQALRIAKAQKKVDKPNVVIPETSHFSFKKACDILGIQMKTVPADRSMRTDISEVSDAIDKNTIALVGIAGSTEYGMVDDIGALATIAEEEDLYLHVDAAFGGLVIPFLPNPPAFDFALPGVSSIAVDPHKMGMSTLPAGALLVREPQMLGLLNIDTPYLTVKQEYTLAGTRPGASVAGALAVLDYMGRDGMEAVVAGCMKNTSRLIRGMETLGFPRAVTPDVNVATFITNHPAPKNWVVSQTRRGHMRIICMPHVTADMIEQFLIDIGE

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-tyrosine/L-aspartate decarboxylase

Organism

Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

Length

363 amino acids

Function

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

39.902 kDa

Sequence

MTYTSGRILGSMCTSSHPLARRVYCDFLESNLGDPGLFRGTRELESGVIGMLGELLSEPDAAGHIITGGTEANLMAMRAARNMAGAEKPEIIVPKSAHFSFRKAADILGLRLREAELDQDYRVDVESVRKLISENTVAVVGVAGTTELGRIDPVEELSEICLDEDIHLHIDAAFGGFIIPFLRETGAELPEFDFKLQGVSSITVDPHKMGLAPIPSGCILFRDASYLDAMSIETPYLTEKQQSTIVGTRTGASAAATWAIMKHMGREGYRKLALRVMGVTRRLRDGLVELDYQLVVEPELNIVAFNHPAMGPHELADRLEELGWAVSVSSCPPAIRVVLMPHIMEEHIELLLRDLEGIRLREE

Protein

Probable L-tyrosine/L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)

Length

355 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

37.357 kDa

Sequence

MTRGEARRPPQEFDRVLSSMCTTPHPAAREAAQAFLATNPGDPETYPAVAERERDAVALLGEIVGLSSPHGYIAAGGTEANLQAVRAARNRADADAVNVVAPASAHFSFQKAADVLGVELRLAPTDGDHRADVAAVADLVDGDTAVVVGVAGTTEYGRVDPIPALADIAAGVDANLHVDAAWGGFVLPFTDHDWSFADAPVNTMAIDPHKMGQAPVPAGGFLARDPETLDALAIETPYLESDTQPTLGGTRSGAGVAGALASLRALWPDGYREQYERTQGNAEYLAAELAARGYDVVDPELPLVAADMPDAEFQALREEGWRISRTASDALRVVCMPHVTREMLAAFLDDVDALA

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)

Length

355 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

37.357 kDa

Sequence

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Length

350 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

37.666 kDa

Sequence

MLQRAEPQDFERVLSSMCTVPHPSAREAAERFLATNPGDPGTYETIAGLEREAVEYLGDITGLSDPAGYVASGGTEANLQAIRIARNRADTDDPNVVAPVHAHFSFTKAADVLGVELRTAPAADYRVNMAAMAELVDEDTVCVVGVAGSTEYGYVDPIPAIADLAETVDALCHVDAAWGGFYLPFTDHDWHFGHADIDTMTIDPHKVGQAAVPAGGLLARDRTLLDELAVETPYLESTDQLTLTGTRSGAGVASAVAAMESLWPAGYRQQYETSMANADWLADQLSARGHDVVGPELPLVAADLSMPMTDELRDRGWRVSKTGAGEMRVVCMPHVTRSMLRSFVADLDWY

Protein

Probable L-aspartate decarboxylase: mfnA

Gene

mfnA

Protein

Probable L-aspartate decarboxylase

Organism

Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)

Length

350 amino acids

Function

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

Similarity

Belongs to the group II decarboxylase family. MfnA subfamily.

Mass

37.765 kDa

Sequence

MQRAEPQEFSRVLSSMCTEPHPAAREAAERFLATNPGDPGTYETVSKLEREAVDMLGEVAGLPDAAGYIASGGTEANIQAVRIARNRADTRTPNFVAPASAHFSFRKAADILGVELRTAPLEDYRANLDGVAELIDSDTALVVGVAGTTEYGRVDPIPALADMAADAGALCHVDAAWGGFVLPFTEHAWDFDDADIHTMTIDPHKMGQAAVPAGGLLARGPELLDELAIDTPYLESTSQVTLTGTRSGAGVASAAAVMDELWRDGYRQQYETAQTNAHWLAAEVESRGFDVVDPVLPIVAMDLPYDLVADLRERGWRLSRTEADEARIVCMPHVTRSMLEEFLTDLDRLA

Protein

Probable L-aspartate decarboxylase: mfnA