Protein
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Function
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
Similarity
Belongs to the AB hydrolase superfamily. MenH family.
Sequence
MSLVCRKFNGYNDRPWLVWLHGLLGCGDEWLPLVNLCAQHPSLVIDLPGHGDSTDVRVKDLLEMSCLLSETLAEQRISQYWLIGYSLGGRIAMHHACYGDIRGLCGLLIEGGNPGLFSQQERNNRLEHDRNWAGRFRSQPIEQVLSDWYQQPVFSDLLPEQRQQLIKVRRHNNGDGVANMLENTSLGHQPWLVPVLQQLTLPFVYLCGENDKKFQHLAKRCALPLQTIPRVGHNAHRANAVAFAAVVNHFLSLFNKEYEYDLPERRRTLFPNCMAGLL