melY

Melibiose permease

425 amino acids

Responsible for transport of melibiose into the cell, with the concomitant import of a proton (symport system) (PubMed:9209070, PubMed:9375783, PubMed:12775706, PubMed:18177889). Can also transport lactose, and has weak activity with maltose (PubMed:18177889, PubMed:12775706). Cannot transport the analog methyl-1-thio-beta,D-galactopyranoside (TMG) (PubMed:18177889).

Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.

46.701 kDa

MNTTTCTHKDNPNFWIFGLFFFLYFFIMATCFPFLPIWLSDIIGLNKTHTGIVFSCISLSAIAFQPVLGVISDKLGLKKHLLWIISVLLFLFAPFFLYVFAPLLKTNIWLGALSGGLYIGFVFSAGSGAIEAYIERVSRNSAFEYGKARMFGCLGWGLCASTGGILFGIDPSYVFWMGSAAALLLMLLLVVAKPKPNQTAQVMNALGANQPQITAKKVFNLFRQRRMWMFILYVIGVACVYDVFDQQFATFFKTFFATPQEGTRAFGFATTAGEICNAIIMFCSPWIINRIGAKNTLLIAGLIMATRIIGSSFATTAVEVIALKMLHALEVPFLLVGAFKYITGVFDTRLSATIYLIGFQFAKQSAAIFLSAFAGNMYDRIGFQETYLMLGCFVLAITVVSAFTLSSRQEIAAAAGAAALTSQSR