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mao

Gene
mao
Protein
Amine oxidase [flavin-containing]
Organism
Danio rerio
Length
522 amino acids
Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA).
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
58.765 kDa
Sequence
MTANAYDVIVIGGGISGLSAAKLLVDSGLNPVVLEARSRVGGRTYTVQNKETKWVDLGGAYIGPTQNRILRIAKQYGVKTYKVNEEESLVHYVKGKSYPFKGPFPPMWNPFAYMDYNNLWRTMDKMGMEIPKEAPWRAPHAEEWDKMTMQQLFDKICWTRSARRFATLFVNVNVTSEPHEVSALWFLWYVKQCGGTMRIFSTTNGGQERKFAGGANQISEGMARELGDRVKLSRAVCSIDQTGDLVEVRTVNEEVYKAKYVILAIPPGLNLKIHFNPELPPLRNQLIHRVPMGSVIKCMVYYKENFWRKKGYCGSMVIEEEDAPIGLTLDDTKPDGSVPAIMGFILARKSRKLANLTRDERKRRICEIYARVLGSEEALYPVHYEEKNWCEEEYSGGCYTAYFPPGIMTQFGRVLREPVGRLYFAGTETATEWSGYMEGAVQAGERASREVMCAMGKLHASQIWQSEPESMDVPARPFVTTFWERNLPSVGGFLKFMGVSSFLAAATAAGLVACKKGLLPRC

Gene
mao
Protein
Amine oxidase [flavin-containing]
Organism
Oncorhynchus mykiss
Length
522 amino acids
Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA).
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
58.937 kDa
Sequence
MTAQNTFDVIVIGGGISGLSAAKLLKEKGLSPVVLEARDRVGGRTFTVQNEQTKYVDLGGAYVGPTQNRILRLAKECGVKTIKVNEEERLVHYVKGKSYPFKGSFPPMWNPFALMDYNNLWRKMDEMGSEIPREAPWKAPHAEEWDKMTMKQLFDKICWTSSARRFATLFVNVNVTSEPHEVSALWFLWYVKQCGGTMRIFSTTNGGQERKFLGGSSQISECMAKELGERVKMESPVYKIDQTGDMVEVETLNKETYKAKYVIVATPPGLNLKMHFNPELPPLRNQLIHRVPMGSVIKCIVYYRENFWRKKGYCGTMVIEEEEAPIGLTLDDTKPDGTVPAIMGFILARKCRKLCGLTKEERKKRICEIYSRVLGSEEALHPVHYEEKNWCEEEYSGGCYTAYFPPGILTQYGKVLREPVGRLYFAGTETATEWSGYMEGAVQAGERAAREVMYEMGRIPQSQIWQTEPESVEVPALPFVTTFWERNLPSVGGFINFLAASVLSVATAAGMLAYQKGLLTRS

Gene
mao
Protein
4-methylaminobutanoate oxidase (methylamine-forming)
Organism
Paenarthrobacter nicotinovorans
Length
421 amino acids
Function
Catalyzes the removal of methylamine from 4-methylaminobutanoate with the formation of succinate semialdehyde. Is involved in the catabolism of 4-methylaminobutanoate produced from nicotine. Has a very weak monoamine oxidase activity with 4-aminobutanoate. Cannot use spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyrate, methylamine propionitrile and methylamino propylamine as substrate.
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
44.431 kDa
Sequence
MGRIGILGAGLAGLAAATKLAEAGENVTVFEARNRPGGRVWSETLDTPKGSYVIERGAEFVLDGYTSMRRLLSQFGLSLVDTGMSYYVREPGDTTGITCDDIIRTGREALELASGSGLQGTAEELLAKLPDEPELVDALRARIEISTAVSASEVTARSLQHIASFEPKPSWRVAGGNQRLPDAMAAALGSAVRYGETVRAVENISDGGVLVTTDTDTSVFDTVVVALPLAVIRDSQLNLPTTEARDAALKHVLQGHAAKLHLPLETQPATSAVMSVEGRYWTWTATDESGAVAPVLNAFMGSPSAITRANLKQRPAEWVAKARALRTDLAIPQDAAALTTVWSEDQLAGGAYAAHAPGVTAAGTALLEKPVGDVFWAGEYSEPEFVGLMEGAIRSGERAAGRVMQRLETKSGNSDSERSKA

Gene
mao
Protein
4-methylaminobutanoate oxidase (methylamine-forming)
Organism
Paenarthrobacter nicotinovorans
Length
421 amino acids
Function
Catalyzes the removal of methylamine from 4-methylaminobutanoate with the formation of succinate semialdehyde. Is involved in the catabolism of 4-methylaminobutanoate produced from nicotine. Has a very weak monoamine oxidase activity with 4-aminobutanoate. Cannot use spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyrate, methylamine propionitrile and methylamino propylamine as substrate.
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
44.431 kDa
Sequence
MGRIGILGAGLAGLAAATKLAEAGENVTVFEARNRPGGRVWSETLDTPKGSYVIERGAEFVLDGYTSMRRLLSQFGLSLVDTGMSYYVREPGDTTGITCDDIIRTGREALELASGSGLQGTAEELLAKLPDEPELVDALRARIEISTAVSASEVTARSLQHIASFEPKPSWRVAGGNQRLPDAMAAALGSAVRYGETVRAVENISDGGVLVTTDTDTSVFDTVVVALPLAVIRDSQLNLPTTEARDAALKHVLQGHAAKLHLPLETQPATSAVMSVEGRYWTWTATDESGAVAPVLNAFMGSPSAITRANLKQRPAEWVAKARALRTDLAIPQDAAALTTVWSEDQLAGGAYAAHAPGVTAAGTALLEKPVGDVFWAGEYSEPEFVGLMEGAIRSGERAAGRVMQRLETKSGNSDSERSKA