Function
Catalyzes the removal of methylamine from 4-methylaminobutanoate with the formation of succinate semialdehyde. Is involved in the catabolism of 4-methylaminobutanoate produced from nicotine. Has a very weak monoamine oxidase activity with 4-aminobutanoate. Cannot use spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyrate, methylamine propionitrile and methylamino propylamine as substrate.
Sequence
MGRIGILGAGLAGLAAATKLAEAGENVTVFEARNRPGGRVWSETLDTPKGSYVIERGAEFVLDGYTSMRRLLSQFGLSLVDTGMSYYVREPGDTTGITCDDIIRTGREALELASGSGLQGTAEELLAKLPDEPELVDALRARIEISTAVSASEVTARSLQHIASFEPKPSWRVAGGNQRLPDAMAAALGSAVRYGETVRAVENISDGGVLVTTDTDTSVFDTVVVALPLAVIRDSQLNLPTTEARDAALKHVLQGHAAKLHLPLETQPATSAVMSVEGRYWTWTATDESGAVAPVLNAFMGSPSAITRANLKQRPAEWVAKARALRTDLAIPQDAAALTTVWSEDQLAGGAYAAHAPGVTAAGTALLEKPVGDVFWAGEYSEPEFVGLMEGAIRSGERAAGRVMQRLETKSGNSDSERSKA