About Products Protein Database Contact

maf

Gene
MAF
Protein
Transcription factor Maf
Organism
Bos taurus
Length
377 amino acids
Function
Acts as a transcriptional activator or repressor. When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T-helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells. It may interact with additional basic-zipper proteins that determine a subtype of Maf-responsive element binding (By similarity).
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
38.987 kDa
Sequence
MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLASAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAAPHYHHHHHHHHAAGHHHHPTAGAPGAAGSASASAGGAGGSGGGSGGPASAGGGGGGGGGGGGGAAGAGGALHPHHAAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFM

Gene
MAF
Protein
Transcription factor Maf
Organism
Homo sapiens
Length
373 amino acids
Function
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters.
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
38.492 kDa
Sequence
MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFM

Gene
Maf
Protein
Transcription factor Maf
Organism
Mus musculus
Length
370 amino acids
Function
Acts as a transcriptional activator or repressor. When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters (By similarity). Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells. It may interact with additional basic-zipper proteins that determine a subtype of Maf-responsive element binding.
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
38.435 kDa
Sequence
MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAAPHYHHHHHHAAGHHHHPTAGAPGAAGGASASASGAGGAGGGGPASAGGGGGGGGGGGTAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSNGFRENGSSSDNPSSPEFFM

Gene
Maf
Protein
Transcription factor Maf
Organism
Rattus norvegicus
Length
369 amino acids
Function
Acts as a transcriptional activator or repressor. When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T-helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells. It may interact with additional basic-zipper proteins that determine a subtype of Maf-responsive element binding (By similarity).
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
38.457 kDa
Sequence
MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPASGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGGAPHYHHHHHHATGHHHHPTAGAPGAAGSASASASGAGGAGGGGPASAGGGGGGGGGGTAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENCSSSDNPSSPEFFM

Gene
MAF
Protein
Transcription factor Maf
Organism
Gallus gallus
Length
359 amino acids
Function
Acts as a transcriptional activator or repressor. Positively regulates the expression of alpha A crystallin genes during lens fiber cell differentiation. Binds to Maf recognition elements (MARE).
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
37.708 kDa
Sequence
MASELAMSGSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGTDQKTHLEDYYWMTGYPQQLNPEALGFSPEDAVEALINSSHHPLPGAFDGYARGQQLAAAAGGSVPAEEMGSAAAVVSAVIAAAAAQGGAPHYHHHHHHPHHGGGGGGGGHPHGAAPGSAPPSSASSSAAGSGGGGGGGGGGAGGLHHPHHGGGGGGGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVEHLKQEISRLVRERDAYKEKYEKLVSNGFRENGSSSDNPSSPEFFM

Gene
maf
Protein
Transcription factor Maf
Organism
Xenopus tropicalis
Length
352 amino acids
Function
Acts as a transcriptional activator or repressor.
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
38.603 kDa
Sequence
MASELAMSSSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKSHLEDYYWMSAYPQQINPEALGFSPEDAVEALISNSNQQQQQQQQQQLQAGYDGFARGQQYASSGGMPGEDMGSAAAVVSAVIAAAAAQNPHHHHHHHHHSVGHQAGVQPPGGGTGGGGSSGSSTSSSVVGALHPPAAHHHHHHHHLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVEHLKQEISRLLRERDAYKEKYEKLLGSGFRENGSSNSDNPSSPEYFMS

Gene
maf
Protein
Transcription factor Maf
Organism
Danio rerio
Length
327 amino acids
Function
Acts as a transcriptional activator or repressor.
Similarity
Belongs to the bZIP family. Maf subfamily.
Mass
35.825 kDa
Sequence
MASELAMSSSDLPTSPLAMEYVNDFDLMKFEVKKEPVEPDRSISQCSRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDFYWMTGYQQQLNPEALGFSPEDAVEALISSSHQLQSFDGYARGQQFGSAAGAGGAMAGEEMGSAAAVVSAVIAAAAAQNGAPHHHHHHHHHHPAGHHHHHAAPGAQSNGASAGHPGHMHLDERFSDEQLVNMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHVLEGEKTQLMQQVDHLKQEISRLVRERDAYKEKYEKLISSGFRENGSSSDNNPSSPEFFM

Gene
maf
Protein
Nucleoside triphosphate pyrophosphatase
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Length
208 amino acids
Function
Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family.
Mass
23.045 kDa
Sequence
MLILASASQARRNLLEQLSIKYAVMVSHIDEGKYNSQNVKELVQALSFAKTESVVSEYIFNCRKENKALAILGCDSLFEFDGEILGKPRNKSEAICRLEKFSSKSGILHTGHCLMYRQNLNNKVIGKSFDGIICDVVSTRINFSELSNVEITKYVETGEPINCAGGFAIDGKGAVFIKSIEGCYSNVIGLSLPWLRYALNKAGMSLWK

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
207 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
23.626 kDa
Sequence
MGCMKIFLASKSPRRRELLENLNFPFQIVENDIEEVSSEKEPSKYVMDLAFKKALKAAENIKEEAIVIAADTIVVVDGEILGKPKDREEAFSMLKTLQGREHIVYTGIAVIKLPEMKHSVDYQETKVWIRRLEDEDISNYIDTGECWDKAGAYAIQGFGSLIVEKIEGDYFNVVGLPVAKLFDLLKREFGVKWVGRGFEYKDKRLAL

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
203 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
22.414 kDa
Sequence
MILLHVRKEGENMKKIILASGSPRRKELLELAGVPFEIVVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYIASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Length
199 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
22.766 kDa
Sequence
MLDNLKKYKIVLGSQSPRRKELLSGLDIRFEQKAMPDIAEDYPAGLDREKVPLYLARMKAEAYRSKGMMQDSTLLITADTVVIIDGTILGKPQDREEAARMLRTLSGRTHQVVTGVCISHRWETRAFSCSSLVTFAHLSDEEIDYYLERYRPYDKAGSYGIQEWIGYIAIQRVEGSFYNVMGLPVHLLYNELKDFGESN

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
197 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.438 kDa
Sequence
MTSHRKLILASQSPRRRELLAMTGIPFETASVEIDETFDPVLTAEENVMEISKQKAEAVLRSISADEACAVVLGSDTTVVLDGKPLGKPGDFDHAFDMLSTLQGRSHEVLTGFCILHNGKAITDYARTIVEIGPMTPREITRYIEVMKPFDKAGSYGIQDPLLACFVTGIDGCYYNVVGLPVSKVYAALKPLFPAEG

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Clostridium perfringens (strain 13 / Type A)
Length
192 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.536 kDa
Sequence
MKVILASKSPRRVEILEKIVKEFEVVQSNFDENTIDFKGDIEKYVKDLSRNKAIEVSKRLNEPSIVISADTVVFQDGKVLEKPKNEEDAFSMLSSLSGNTHKVYSGICLINTYDDTVVTDCDCTEVRFSELNPRQIRNYINSGEPMDKAGAYGIQGLGGAFVEGIKGCYYNVMGLPLNKLYKALENYDITIL

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.047 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDYIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus clausii (strain KSM-K16)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
20.972 kDa
Sequence
MNTFLLASSSPRRSEFLKQCHYQFFTQPSNVEETFDPTWENDTIVKELARRKAASVAANHPNAVVLGADTIVVHNGKHLGKPANVAEAKTMLMALSNSTHTVYTGVAILHGNKEHVFSDAAKVTFDELTPERLERYLQSGDSLDKAGAYGIQSFGAIFVSRIEGDFYTVAGLPLSKTAKALEKFHIYPNIG

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.023 kDa
Sequence
MRKIILASGSPRRKELLELADVPFEIVVSEVEETIGAYSSPSDIVMSLALQKASAVAENHSNQVVLGADTIVTYDSRILGKPSNEAEAKEMLRLLSGKTHEVYTGVAIISKEKTVTFYERTEVTFWGLTEEEIDVYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPIARLVRELKQFDSDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus anthracis (strain A0248)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.02 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus anthracis (strain CDC 684 / NRRL 3495)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.02 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus anthracis
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.02 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain AH820)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.021 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain G9842)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.119 kDa
Sequence
MKKIILASGSPRRKELLELASIPFEIVVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEDEAKEMLQLLSGKTHEVYTGVAIISKEKTVTFYERTEVTFWELTEEEIDTYVTSKEPLDKAGSYGIQGKGSIFVQNIQGDYYSVVGLPIARLVRELKQFDIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain 03BB102)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.021 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain B4264)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.087 kDa
Sequence
MRKIILASGSPRRKELLELASVPFEIVVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEDEAKEMLQLLSGKTHEVYTGVAIIAKEKTVTFYERTEVTFWELTEEEIDTYVASKEPLDKAGSYGIQGKGSIFVQNIQGDYYSVVGLPIARLVRELKQFDIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain AH187)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.114 kDa
Sequence
MRKIILASGSPRRKELLELASVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAEYNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYIASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
20.957 kDa
Sequence
MKKFILASGSPRRKELLELANVPFEVVVSEVEETIGAYSSPADIVMALALQKASAVAETHEESIVLGADTIVTYDSRILGKPKDAAEAKEMLQLLSGKTHEVYTGVALMSKEKTVTFYERTEVTFWELTEEEIDVYIATKEPLDKAGSYGIQGKGAIFVQHIQGDYYSVVGLPIARLVRELKQFDSGASHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain Q1)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.14 kDa
Sequence
MRKIILASGSPRRKELLELASVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAEYNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYIALKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.121 kDa
Sequence
MRKIILASGSPRRKELLELASVPFEIVVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEDEAKEMLQLLSGKTHEVYTGVAIIAKEKTVTFYERTEVTFWELTEEEIDTYVASKEPFDKAGSYGIQGKGSIFVQNIQGDYYSVVGLPIARLVRELKQFDIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus cereus (strain ZK / E33L)
Length
191 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.035 kDa
Sequence
MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYIASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
190 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.329 kDa
Sequence
MTRQLILASQSPRRKELLDLLQIPYSIVTSNAEEKLIRNFSPAENVKWLAEQKVRAVAEQYPDAVVLGADTIVYYDGAYLGKPKDAEDAERMLSMLSGQTHSVLTGVCIKDGERCETFFEETEVSFWPLEEKEISAYIATGEPFDKAGSYGIQGKGALFVKQIKGDYYTVVGLPISKTMRMLKTFDLHSF

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
190 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.24 kDa
Sequence
MKPLILASGSPRRKQLLEQMNVPFTVCKSTIDETFDPTFPPDEVVQQLARQKAQDVAKKHEDSFILAADTIVVFQGRILGKPATEQEARQMLSQLSDQSHEVLTGVALLHQGQVETFVETTEVRFWPLTDTEIETYLQTGEPFDKAGAYGIQGLGAYLVKELKGDYYNVVGLPLSRTVRALKVHGFSTRF

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus pumilus (strain SAFR-032)
Length
189 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.058 kDa
Sequence
MNQLILASQSPRRKELLDLAGFSYDIQASHLKEEINRNLSPAENVQWLAEQKANDIQRLNPKAVVIGADTIVAIDGKCLGKPKDKKEAAFMLQLLSGKTHQVLTGVTVQSENRKETFYEQTEVTFWTLTQNEIDRYIETGEPLDKAGSYGIQGKGALFVQKIDGDYFSVVGLPIAKTVRVLETFGITPF

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus subtilis (strain 168)
Length
189 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo-UTP, 5-methyl-CTP (m(5)CTP) and 5-methyl-UTP (m(5)UTP) (PubMed:24210219). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids (PubMed:24210219).
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.295 kDa
Sequence
MTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEENVQWLAKQKAKAVADLHPHAIVIGADTMVCLDGECLGKPQDQEEAASMLRRLSGRSHSVITAVSIQAENHSETFYDKTEVAFWSLSEEEIWTYIETKEPMDKAGAYGIQGRGALFVKKIDGDYYSVMGLPISKTMRALRHFDIRA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)
Length
189 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
21.023 kDa
Sequence
MTKRLILASQSPRRKELLNLLQIPYSIIASRTEEKLNRNLSPEENVQCLAEQKAGAVLAENPDAVVIGADTMVCIDGECLGKPHDREEAAHMLRRLSGRSHQVITAVSIQTHDRKETFCDTTEVTFWPLSEDDIQLYIETKEPMDKAGAYGIQGKGALLVKKIDGDFYSVVGLPVAKTMRALKEFNIKA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
186 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
20.434 kDa
Sequence
MLASRSPRRRQILELAGWPFDVQESHADETIPPGTPPDEAVQLLARRKVEAVMSSFPDAYVLGADTIVVCDGRLLGKPRTEEEAFAMLRQLSGRTHDVWTGVAIALPQGSITSFAEKTAVTFWELDDEEIAAYIATGEPMDKAGAYGIQGRAALFVKRIEGDYLTVVGLPLSRTVRELRRLGWPPA

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Geobacillus sp. (strain WCH70)
Length
186 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
20.91 kDa
Sequence
MKQLILASSSPRRKQLLELANLRFQILASHIDEQIHETKSPEQAVQLLAYRKAKAVADHYPHSYVIGADTVVVYQDNILGKPKTEEEAAAMLRMLSGNEHHVLTGVAILSPNGQSLFVEKTKVFFWDLTEEEIFDYIATGEPMDKAGAYGIQGRAALFVKRIEGDYFNVVGLPLSRTVREVKRLGW

Gene
maf
Protein
dTTP/UTP pyrophosphatase
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
184 amino acids
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Mass
19.843 kDa
Sequence
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN