Lon

Lon protease homolog, mitochondrial

1024 amino acids

ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by stabilizing the mitochondrial TFAM:mtDNA ratio via selective degradation of TFAM.

Belongs to the peptidase S16 family.

115.033 kDa

MLARAIRVRPMMRGIASSSVWNRNRPIQSSLMQYCRDRSLRLQRLHGANLMVQRFYSRKRDDSNGDIIMGPDLMSDQDTHLPATVAVPDVWPHVPLLAMRKNPLFPRFMKIVEVSNPIIMDLLRRKVKLNQPYVGVFLKKTDGEEELITNLNDVYNLGTFAQIQELQDLGDKLRMVVVAHRRIRITGQVVEDVPPPKPVKMTTLHYPLFNIKLQIPAEDQSTDQADAAPIKSRSDPARKPRGRIPRSRTGKSRESAAAEELIQNQTLEPPLKSGKVESSSLPKPPTEEKIVEPETGAKENVNQSAPSAQPVLIVEVENVKQPIYKQTEEVKALTQEIIKTLRDIITMNPLYRESLQQMLHQNQRVVDNPIYLCDLGASLSAGEPAELQKILEETDIPERLQLALTLLKKELELSRLQQKIGREVEEKVKQQHRKYILQEQLKVIKKELGIEKDDKDAIGEKYREKLKDKVVPEAIMTVIDEELTKLNFLESHSSEFNVTRNYLDWLTSLPWGVISTENLCLEKATETLNDDHYGMEDIKKRILEFIAVSSLKGSTQGKILCFHGPPGVGKTSIAKSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKLIQCLKKTKIENPLVLIDEVDKIGKGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSRVLFICTANVIDTIPEPLRDRMELIEMSGYVAEEKIAIARQYLMPQAMKDCGLTDKHINISEDALNMLIRSYCRESGVRNLQKHIEKVIRKVAFRVVKKEGEHFPVNADNLTTFLGKQIFSSDRMYATTPVGVVMGLAWTAMGGSSLYIETSRRHIRQGAKTDPNTVAGSLHITGNLGDVMKESAQIALTVARNFLYSLEPNNLFLEQEHIHLHVPEGATPKDGPSAGITIITALVSLATGKPVRQDIAMTGEVSLKGKVLPVGGIKEKTIAARRSGVNCLILPVDNKKDFEELPTYITDGLEVHFATTYEDVYKIAFTDVTETTTNNVEEQEPLQKLSSAAAAKSETWPYS

lon

Archaeal Lon protease

998 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively (By similarity).

Belongs to the peptidase S16 family. Archaeal LonB subfamily.

111.704 kDa

MLKFYKMGIKRLSGEMTMGEERMDLGIEFETTEEIPVPERLIDQVIGQDHAVEVIKTAAKQRRHVLLIGEPGTGKSMLGQAMAELLPTEDLEDILVFPNPEDENMPRIKTVPAGQGRRIVEEYKRKAKEQENIRFYLLFFVFFIVAMAVFMSRGDPNTLLLGVFVILIALMVTANMRFRTQAMVPKLLVDNSGRKRAPFVDATGAHAGALLGDVRHDPFQCFSGEETVVIRENGEVKVLRLKDFVEKALEKPSGEGLDGDVKVVYHDFRNENVEVLTKDGFTKLLYANKRIGKQKLRRVVNLEKDYWFALTPDHKVYTTDGLKEAGEITEKDELISVPITVFDCEDEDLKKIGLLPLTSDDERLRKIATLMGILFNGGSIDEGLGVLTLKSERSVIEKFVITLKELFGKFEYEIIKEENTILKTRDPRIIKFLVGLGAPIEGKDLKMPWWVKLKPSLFLAFLEGFRAHIVEQLVDDPNKNLPFFQELSWYLGLFGIKADIKVEEVGDKHKIIFDAGRLDVDKQFIETWEDVEVTYNLTTEKGNLLANGLFVKNSGGLGTPAHLRVEPGMIHRAHKGVLFIDEIATLSLKMQQSLLTAMQEKKFPITGQSELSSGAMVRTEPVPCDFILVAAGNLDTIEKMHPALRSRIRGYGYEVYMRTTMPDTVENRRKLVQFVAQEVKKDGRIPHFTRDAVEEIIREAQRRAGRKGHLTLRLRDLGGVVRAAGDIAVRKGKKYVTREDVLEALQMAKPLEKQLADWYIERKKEYQVIRTEGGEIGRVNGLAIIGEQSGIVLPIEAIVAPAASKEEGKIIVTGKLGEIAREAVLNVSAIIKRYKGEDISRYDIHVQFLQTYEGVEGDSASISVATAVISALEEIPVRQDVAMTGSLSVRGEVLPVGGVTPKIEAAIEAGIKKVIIPKANEKDVFLSPDKREKIEIIPVERIDEVLEVALVESEKKKELIKRIRETLPLGVSESAGSETLHEHGRDSGSALSVEESKA

lon

Lon protease

996 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity).

Belongs to the peptidase S16 family.

113.743 kDa

MLFDREVAKLEITDELITQTTYWKQIIDEYTKDNSNGAEIINKARIMLVYYRPAEDNRVILESELQSKPTATYADVLENVNISNLDSNMTLCQVESVEKVYDNGSQKWHYIATLKAIHKYILQDIYGDEETISSSSIDIEKLPLKYIEGMVATRFGSENNGDEMALADPSLDFNGFEEVINTLIYDRNWNDAMLLYRYIRGYSAKEIRNWTKGTSEMMPDFINDDESRLETLVRALTGFFLLPPYELFTIYSMPSALHQFEALKSNFVLMVRLIKKFINELNLGNTDKLLNIYNALTDNELFKNSMEQIKENSELEVQFNYEVERIYKWHKEYLQLGYITEDDLKLIISLIEQNQNNLSKRSSKKDTSAMKDKIDKELNKKIQSNLDKQQKEFLLREKMKAIKEQLNEADDEDGDDEYSKIVNDPVLKQMYPEWIIKAIKTERDKLKNMMSSSPDANITQTYISNLKKLPWRKVEVENLDINRAREILDKNHYGLKEVKERVIEYLSLIINHRNINKESSEKDLIKIDDHNQIDLQLFKENTKNKAQKQFNNVPILTLVGPPGTGKTSLARSIAEALDKSYVKLSLGGLHDESEIRGHRKTYVGAMPGKIIKGLQSAGVSNPLILLDEIDKMSSDIKGDPTSAMLEVLDPEQNTKFQDNYIEHEYDLSKVLFIATANYYENIPAPLLDRVEIIELNSYTINEKIKIAKEHLVEVVLAQAGLKPDQFIIDDKALEFIIKHYTAEAGVRSLKRNLDKIARKIVTKIVSGEKIDKFVIDQNNIPELLGTPKISESEKEMQPQIGSVNGLAFTSIGGTTLQIEVSWFKSKQPGIRLTGQLKEVMQESAKIALSYVRANAEKFGIKNVDFDTTEIHVHVPEGAVPKDGPSAGVTFTTALISALAKIPVSQEVAMTGEITLRGKVLEIGGLKEKSFAAFKKGIKTVFIPKNNEKNLSDIPEEVKEAINFIPVSHYEQIWEHLFKGKKSDESETESKKKKQSK

lon

Lon protease

890 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity).

Belongs to the peptidase S16 family.

102.244 kDa

MQKKQTLNYVIVKTDEISFPFGYSEVLILEQDSIELLETTKFKFKNEDRLVIVYAEDVYTEEVKFLQRGLYIKPLDAKEVMYQGEKALILTFKALHFFDIQNFSYEMNQDEIMSANFLVDGNAKGTVGYEMVLSGHINNVEDVKENLMNEFRQDQNKMNFFSIFETLVNNSNSFGISTNNQAGTAMLFKQNYGAKDEVKPYDIEEIKALIDSKITQDNDPSEFLLNNFESLMTYFGFLDLNKFPHKWHLYNSFDYGNFTRLINEVGNFIQTALKLEENITSEISKKLNNQQKEFMLREKRKVIDDELAKLGKDTLQDDKDEYVKKLKNKTLKKMYPDSIKEIIRDETKRYSEMMQASPEANLVKNYVEYLKKLPWRKVSKDRLDIKYAREVLEKYHYGIKEVKERILEHLGVLINAQTYNKNYKNEVVSIDENYEIDLNLFKDKPSEKTVFNNVPILALVGPPGTGKTTLAKAISEALNKKYVKISLGGVKDESEIRGHRRTYVGAMPGKIVKGVAKAGVSNAVFLLDEIDKMASDHKGDPASAMLEVLDPEQNAQFQDHYLEQEYDLSKIIFIATANYFQNIPEALIDRVEVIELDPYTLNEKVQIAQKHLIPKVINEVYLDEKLFNIPEETLRFIINRYTREAGVRGLKRILDKIARKIVIKRVLEPDLKSFDISLNNLEELLGVAPYKTDEDKHDEIPGIATGLAYSTHGGSDLEIEVNVFKSEKGGIQLTGSLKDVMKESAQIALTYVRSNAKYFGIHSFDFDKHTIHIHVPEGATPKDGPSAGVTFTTAIISALTRLPVPNNYAMTGEITLQGKVLPIGGLKEKSFAAYWKKIKYVFIPHANIDNLQKIPDEIKREITYIPVKRYDEIFQILFRDQKPENTITFN

lon

Lon protease

881 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

97.728 kDa

MAKNTDIEHDAHEPAGHGDVRESAVENPSASAVSDGEERATFAPEVAPQTDTESAQGAAQESEPEVQRAGEAEKGVPEKAKAVVPLDELLPQKVHLIPLTGRPIYPGIFTPLLISDEDDVRSVESAYSDSGFIGLCLVKTDTQNPTISDLYEVGSVARIVKKINLPDGGLNVFISTQKRFRIRKHVHHSKPIVAAVQYLSDLIEGDPLEIKALVRGLIGEMKELSENNPLFSEEMRLNMINIDHPGKIADFIASILNISKEEQQRTLEILDVRKRMEEVFVYIKKEKDLLEIQRKIQNDLNSRVEKNQREYFLREELRSIKEELGLTTDPKERDQRKFRALIDSFHFEGEVKEAVESELEKLSLTDPNSPEYSVGRTYLETVLSLPWHAPEKEEYDLKKAQKLLDEDHYGLENVKERIVEYLAVRKLRADTKGSIILLVGPPGVGKTSVGKSIARAIHKPFFRFSVGGISDEAEIKGHRRTYIGALPGKVLQGLKIVKTKAPVFMIDEVDKIGSGARGDPAGALLEVLDPEQNTTFRDHYLDLPFDLSHIVFVLTANSTDPIPRPLLDRAEIIRLSGYIDTEKVEIAKRHLVPKTLEKNGLKRACVSYRKEVLLHLVHSYARESGVRGLEKSLDKLHRKLATEIVLGKRSFDDKCLMDEALIGTFLGKPVFRDDMLKDANKVGTAVGLAWTGMGGDTLLVEAITIPGKASFKLTGQMGAVMKESASIALSWLRRYSAQQRIASPNWFEKRAIHLHIPEGATPKDGPSAGITMTTTLFSLLTQQKVKPRLAMTGELSLTGQVLPIGGLKEKTIAARRGGIKEIIMPKANVRDLDEIPEHVKKGMVFHLVESMEEVLSLAFPKGKRVRAGTAAQSASPETLTG

lon

Lon protease

880 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

96.389 kDa

MADYNDKNYLLHMSGPDSDTGPGIENEDPRAVENPGHDLAESEGGLAAAMQSIPDTLPILPVRDVVIFNYMILPLFIGREKSVQAVEAALKSGRHLLVCAQKEEATEDPGPEDIYQVGTVVQVMRMLKMPDSRVKILVQGVSRARVREFSQVEPFLEAHIETLPEATPKVDATVEALLRSVREQSEKVLSLRGLSSPDVLAVLQGVDDPGRLADLIAANMRMKTADAQQILETEDPLDRLMLVNTQLQREVEVATVQARIQSSAREGMDKAQKDYFLREQLKAIRSELGDKDDEGEEELESLRAALDKAGMPKDVRKEADKQLRRLAGMHADSSEANVVRTYLDWLAELPWKKLSRDRLDIAHAKQILDEDHCGLEKIKDRILEFLSVRKLNPQSKGPILCFAGPPGVGKTSLGRSVARALGRKFQRLSLGGMHDEAEIRGHRRTYIGAMPGRIIQSLKQAGTRNPVIVLDEVDKLGADFRGDPSSALLEVLDPEQNHTFSDHYLNVPFDLSKVMFLCTANHLETIPAPLRDRMEVITLPGYTMQEKAEIARKHLLPKKIKENGLQEKDVTLDDAALEKVIREYTREAGLRNLERELSSICRKLARRKAEGKKGPFRVSTADVEKLLGAPRFIEDEKEKKLMPGMALGLAWTPAGGEVLTVEATVMKGKGGLTLTGQLGDVMKESAQAALSYIRSRAEELGVDPSFVSEYDIHVHVPAGATPKDGPSAGVTLTTALISALNGHRVRADLCMTGEITLQGRVLPVGGIKEKILAGVARGLKHVVIPWQNTKDLEDVPKELLKRITVHPVHHYDELLPLVFEGKSGKGGVSGAGQAGDKGGKSKAAAGKKDVVAARPAKPAAPARRRKDKTEDELPTAEAGA

lon

Lon protease

880 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

96.389 kDa

MADYNDKNYLLHMSGPDSDTGPGIENEDPRAVENPGHDLAESEGGLAAAMQSIPDTLPILPVRDVVIFNYMILPLFIGREKSVQAVEAALKSGRHLLVCAQKEEATEDPGPEDIYQVGTVVQVMRMLKMPDSRVKILVQGVSRARVREFSQVEPFLEAHIETLPEATPKVDATVEALLRSVREQSEKVLSLRGLSSPDVLAVLQGVDDPGRLADLIAANMRMKTADAQQILETEDPLDRLMLVNTQLQREVEVATVQARIQSSAREGMDKAQKDYFLREQLKAIRSELGDKDDEGEEELESLRAALDKAGMPKDVRKEADKQLRRLAGMHADSSEANVVRTYLDWLAELPWKKLSRDRLDIAHAKQILDEDHCGLEKIKDRILEFLSVRKLNPQSKGPILCFAGPPGVGKTSLGRSVARALGRKFQRLSLGGMHDEAEIRGHRRTYIGAMPGRIIQSLKQAGTRNPVIVLDEVDKLGADFRGDPSSALLEVLDPEQNHTFSDHYLNVPFDLSKVMFLCTANHLETIPAPLRDRMEVITLPGYTMQEKAEIARKHLLPKKIKENGLQEKDVTLDDAALEKVIREYTREAGLRNLERELSSICRKLARRKAEGKKGPFRVSTADVEKLLGAPRFIEDEKEKKLMPGMALGLAWTPAGGEVLTVEATVMKGKGGLTLTGQLGDVMKESAQAALSYIRSRAEELGVDPSFVSEYDIHVHVPAGATPKDGPSAGVTLTTALISALNGHRVRADLCMTGEITLQGRVLPVGGIKEKILAGVARGLKHVVIPWQNTKDLEDVPKELLKRITVHPVHHYDELLPLVFEGKSGKGGVSGAGQAGDKGGKSKAAAGKKDVVAARPAKPAAPARRRKDKTEDELPTAEAGA

lon

Lon protease

874 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.415 kDa

MTQLPHVRVDHMPQIRVLPVLPLDDAVVLPGMVVSLDMSDEQTRAAVDAARTGGSAGSSDARAPGISSRAAGRPAEVLLVPRVGGELAEVATVGVIEQVGRLPRGGSAAVVRGTARAQVGGVRPAPAGTDTTGTGTADATSGAGSGAGVQWVDAVVLDDSAATPFGALDDPAGTRAGSPADEAARVDKLAKEYRALVTDLLRQRGAWQVVDSVSAITDPGTLADTAGYSSYLTTAQKIELLGTPAVGTRLERLLTWTKEHLAEQDVAETIRRDVQEGMDRQQREFLLRRQLEAVRKELSELDGSGGGADGASGSEPADYRARVEAADLPEKVRAAALKEVDKLERTSDSSPEGGWIRTWLDTVLDLPWNVRAEDSYDIIAARAVLDADHAGLDDVKDRIIEHLAVRRRRADAGLGVVGGRRGGAVLALAGPPGVGKTSLGESIARAMGRSFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAIREAGSMNPVVLLDEVDKLGADYRGDPTAALLEVLDPEQNHTFRDHYLEVELDLSDVLFLATANVLEAIPAPLLDRMELIRLDGYTEDEKVVIARDHLLHRQLDRAGLAEGDVSVGDDALHALAGEYTREAGVRDLERSIARLLRKVVAQVALGAAALPVTIDAGDLTGYLGRPRHTPESAERTALPGVATGLAVTGAGGDVLFVEASLADAETGGGGITLTGQLGDVMKESAQIALSYLRSHGVELELPVGDLADRGVHVHVPAGAVPKDGPSAGVTMTTALASLLSGRPVRADVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGLTTVLLPQRNGPDLDDVPAPVRDALTVHLVTDVREVLDLALEPAFDADHGGRSPGRAGHSPTALAA

lon

Lon protease

870 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

98.728 kDa

MPTNSYRFLVASEDIYFQNTLQQSITFSDPESIKVLKDFYHSNSRPTLTNKDFLIVYRKEKEKDTKKKNSSVIKFPRNDFNSFEDSKNDIQNQAKILNGKVGDFENSLLPRIYDLDELSKYASLARIQSYRAKTSPDKSEWQTVILDFIVTEKVQLVELINDPQNPKVGQIIIKPVRETIKSPEIHINLINDLLEMARKAKNFRIPTELLLIVDKFGANSEYSTNEYIKGVTNTLSCSPSLTYPQKYQLFSYNSYPAKIKKLYEHIHTFAEQIKLEDEINVILKTNLDKQQTEFILKEKIKAIRKKLGEDSRYEDEIEELLHSELGKKVFPKEVAKTIMRETNKLKSMIVTSPESNITKSYLDLLVALPWKKVKKDILDIKNVREKLEEAHYGLDEIKKRIIEYLAALIHRRSQSEGKPELEKVGSDYIDSNLFLSHKIRKVRSNSIPILTLVGPPGTGKTSIAMAVAEAIGKEFVKISLGGIRDEAEIRGHRRTYVGALPGKIIQALKKVGVSNPLILLDEIDKMGADFKGDPSAAMLEVLDPEQNRFFQDHYLELEYDLSQVLFVATANEIYDIPEPLLDRVEIIELSSYTFIEKIQIAKSHLIPAVLKENALDPKYFPIQDQTIDFLIRHYTREAGVRGLKRVIDKIVRKIIVKLLEKTLDQNFVIDIEFVRELLGIEKYDPDNVDSSPQIGTVTGLGYSPLGGSTLQIEVSTIPGRGDIKLTGSLKDVMQESARIALSYVQSKAKDFGINFDFENTLIHIHVPEGAIPKDGPSAGITFATAIISALSQKPVSHNIAMTGEITLRGKVLAIGGLKEKTMGAYKNGIKIIFIPKANEKNLVDIPQEVKDVIQFIPVDTYQQIYDFIFK

lon

Lon protease

856 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.404 kDa

MVNTPVPGLGSCASRGLIAAPASIIRSRPGCDHAGECIVVCVGVFRKDWVMTSPKQRPPLVPGVAQTFPVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMRGDTYILLATQENASDDDPATDAIYRVGTLATVLQLLKLPDGTVKVLVEGVTRAQVVQYTDRADLYEAEAISLPDEVGDVVEAEALARSVVNEFENYVKLNKKVSPEVVGVVGQIEDHAKLADTIASHLAVKIPEKQAVLETVKVADRLEKVLGLMESEISVLQVEKRIRTRVKRQMEKTQREYYLNEQMKAIQKELGDEDGRDDLQELEDRIKRTKLTKEAREKATHELKKLRQMSPMSAEATVVRNYLDWLLSIPWGIKSKVKKDLPFAQSVLDSDHYGLDKVKERIVEYLAVQSRANKLAGPILCLVGPPGVGKTSLGRSIAKATGREFVRVSLGGVRDEAEIRGHRRTYIGSMPGKIIQSMRKAKKSNPLFLLDEIDKMGADFRGDPSAALLEVLDPEQNPTFNDHYLEVDYDLSNVMFVTTANTLNIPPALLDRMEVIRIAGYTEDEKAEISRKHLIPNALQKHGLSAKEWSIDDAALLQVIRRYTREAGVRNLEREISTLARKAVKELVISKKKSVKVTAKNLETFLGVPRFRYGEIEREDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLKEVMKESISAAASYVRSRSVDFGIEPPLFERRDIHVHVPEGATPKDGPSAGVAMATTIVSVLTGIPVRRDVAMTGEITLRGRVLPIGGLKEKLLAALRGGIKKVLIPEENAKDLADIPDNVKNALEIIPVSRMDEVLHHALLRHPEPISWTEQPVSGAVVPDEDAAGVVAH

lon

Lon protease

855 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

98.939 kDa

MLLHETESEYDSKSKKNNYSYYESSDFKPLIEKYNRIKYSVTEYIYLLTVKNVVLFPDVVIPITAVKQKSINLFKSAYYTYKKIGILTKKYFNTTFSIAKLNIQTFNIYSFNKFNKINKFNKINKFNKINKFNKINKFNKINKFNKTNNIYYIGTVAKILKLLIMPDGNTTVILQGISRFKIIKLIQVYPYFKAEIIYLKDEKPQKKDKEYLILIDSIKEIAIKIIQDNYKIPSESSFAISNIESKSFLINFVAYNLNIEIKNKQILLEYDFLKQRAIETFRFLNIEYEKIKLKNDIQYRVRYDIDQQQKEYFLNQQIKALQEELGDFSYEKEVEVLRIKSYKKNWSKEAQNQFDRELSKLKRTNPQMPEYTILRNYLDLMLDLPWKKYSQDNYDLYRAQKILDKDHFGIDKVKERIIEYLSVLKLKGDLRSPILCFYGPPGVGKTSLGRSIASALNRKYVRISLGGLNDEAEIRGHRKTYIGAMPGRVLQSIKKAGTSNPVFVLDEIDKMGLGSQGNPSSAMLEVLDPEQNKEFYDNFLEMGYDLSKVIFIATANSLYTINIALLDRMEIIDMNGYTVEEKIEISKKHLIPKQLKENGLKSKDIILGVKQIEKIIESYTRESGVRSLEKNISKIVRYAAKNIAMNKKYLKRINMSKIEEVLGPPNDPEKYELIQVPGVVTGLAWTIVGGEIIYIESTLLKGRGNLSITGNVGEVMKESATIAFKYIKAHNYEFGIDEKMFELYNIHIHAPEGGIHKDGPSAGITMLTSIISSFLKKKIRPYLAMTGEITLRGKVLPVGGIKEKILAAKRANIKEIILSKANKKDIDDIKKVYLKGLKFHFVSKMNEVIDLSIIK

lon

Lon protease

850 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

93.449 kDa

MQHLADGPITGPSAFLFPQIPIPAERPMAQSQPEVLDLPVLPLRDVVVFPHMVIPLFVGRDKSMRALEKAMEADKRILLVAQKSAETDDPAAVDLHTVGTLAQVLQLLKLPDGTIKVLVEGLSRVTVDKVVEQDGALQGQGTEVEASDAREPREVEAIARSLMSLFEQYVKTNRKLPPELLQTLAGIDEPGRLADTIAPHIGVRLADKQRLLEITDIGERLELLVGLVDGEIDVQQLEKRIRGRVKSQMEKSQREYYLNEQMKAIQKELGDLDDVPGELEELARKIAEAGMPKPVETKAKAELNKLKQMSPMSAEAAVVRNYLDWLLGVPWKKRTKVRKDLKVAEDTLDADHYGLDKVKERILEYLAVQSRVKQMKGPILCLVGPPGVGKTSLGQSIAKATNRKFVRMSLGGIRDEAEIRGHRRTYVGSMPGRLVQNLNKVGSKNPLFLLDEIDKMSMDFRGDPSSALLEVLDPEQNNSFNDHYLEVDLDLSEVMFVATSNSLNIPGPLLDRMEVIRIPGYTEDEKLNIAMRYLVPKQIKANGLKPEEIEIGGDAIQDIVRYYTRESGVRNLEREVAKICRKVVKEIALAGPQPAAKKAVAKKGKPKALVTVNAKNLDKYLGVRRFDFGRAEEENEIGLVTGLAWTEVGGELLQVESTLVPGKGNLILTGQLGNVMKESASAALSVVRSRAERLGIDVDFLQKQDVHVHVPDGATPKDGPSAGIAMVTSLVSVLTKVPIRADVAMTGEITLRGRVSAIGGLKEKLLAALRGGIRTVLIPGENRKDLADIPANVTRDLKIVPVKWIDEVLDLALERPLTPKKAGKEKARKTAPRVAVRGKSRSTPGTRVKH

lon

Lon protease

845 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

95.966 kDa

MIDRKYIRLGEDDEDDGFPVFFPVLSVCEEDEDFKVKEDHMQEEMPILALRNMILFPGVAMPIMVGREKSLKLIRYVEKKGVYFGAVSQRDMDVEEPDRADLYDVGVVAEIIRVLEMPDGTTTAIVQGRQRFALQEITATEPFMKGRVKLLPDILPGKNKDHEFEALVSTIQDMSLKMMELMVERPPRELILSMRRNKNPMYQINFASANISTSIAVKQELLEISKMKDRGYRLLYLLHKELQVMELKASIQMKTREEMDKQQKEYFLQQQIKTIQEELGGNINDIEVQELRTKATTMKWSSEVAETFEKELRKLERLHPQSPDYSVQMQYVQTIISLPWGVFSKDNFNLKRAQSVLDRDHFGLEKVKERIIEHLAVLKMKGDMKSPIICLYGPPGVGKTSLGKSIAESLGRKYVRISLGGLHDEAEIRGHRRTYIGAMCGRIIQSLQRAGTSNPVFVLDEIDKIDSDYKGDPSSALLEVLDPEQNNAFHDNYLDIDFDLSHVLFIATANSLSSISRPLLDRMELIDVSGYIIEEKVEIAARHLIPKQLVEHGFRKNDIKFSKKTIEKLIDDYTRESGVRTLEKQIAAVIRKITKEAAMNVVHTTKVEPSDLVTFLGAPRYTRDRYQGNGDAGVVIGLAWTSVGGEILFIETSLHRGREPKLTLTGNLGDVMKESAVIALDYIRAHSDELGISQEIFNNWQVHVHVPEGAIPKDGPSAGITMVTSLVSALTRRKVRAGIAMTGEITLRGKVLPVGGIKEKILAAKRSGITEIILCEENRKDIEEINDIYLKGLKFHYVSNINEVLKEALLEEKVIDTTDIYSFGKKTEEEKAEKVEKTEKKQRKK

lon

Lon protease

843 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.373 kDa

MRERKETAMSDKEKKGAGAGAQVAPAMGPPVLINKEDIPAVLPILPLRNSVFFPGGVLPLAVGRQKTIALIKDAVRDEQVIGVVTQRRAEEEDPGAADLYTVGTVARVVKLLKMGEDNYSLVVQGLARFKVLELVQESPYLKARIEAVEDRSVVDDVEVEALAINLKKLAREVIELMPELPAAATELVESITHPGHLADLIAANVDVPIEEKQQVLETVELKARMKLVLELLNRKREILKLSNKIDSAVKGEMSKTQREYYLRQQLKAIKEELGELGEEEEELDELQERLKKAGLPPEVEKVAQKELNRLKSIPTASSEYTVARTYLDWIADLPWTKRTDDNLDIENARQILDTDHYGLDKIKKRILEYLAVRKLKNDMRGPILCFVGPPGVGKTSLGQSIARATGRKFVRLSLGGVRDEAEIRGHRRTYVGALPGRIIQSMKKAATVNPVMMLDEIDKLGADFRGDPSAALLEVLDPEQNHAFSDHYLDLSYDLSKVMFIGTANLLDPIPGPLKDRMEILELPGYTFEEKVHIAQNHLIPKQLREHGLSADAIAISEKALIKIIMAYTREAGVRNLERRIADVCRAIAVEVASGKIGASAKRSIEEADVLEILGPEKFYNETAERTEIAGVATGLAWTAAGGDILFIEATKMPGKGALTLTGQLGDVMKESAQAALSYLRSKSDSLGIPVNFLEKTDLHIHFPAGAIPKDGPSAGVTILTALVSLLTGIRVRSDVAMTGEVTLRGLVLPVGGIKEKVLAAHRAGIKRIIIPARNEKDLLDVPEQARKELEFVFAAHMDEVLQAALEENPVGRKPPAAPEPEGEKKPGATPTPPAKKPDEIRV

lon

Lon protease

839 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.786 kDa

MEGGPLEPLEDLSGIEENSIIPLDSILPPELFLIPIKSRPVFPGIITPLIVPSGKFAKAVEETVKGNSFLGLVLLKDEENEKETSENIYQYGVVAKILKKVNLPDNAVNILVNTIRRFKIESFVNKDPLVARVSYPEEEPGAPKNTTKAMMRTLLVMTRELAQNNPLFTEEMKLTMLNVNEPGKMADFVCSILNLEKEEYQSVIESNILKTRIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQRQFFLREQLKAIQNELGIKDDKFEKKYEKFLERLKNLNADPEVIEEVTRELDKFSYADPNTGDYNVIRNYLDILESLPWEPAPVREIDLEKAKKTLDKDHYKLEDVKDRILEFLAVKKLKNDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGGMRDEAEIKGHRRTYIGSMPGKIISALRITKERDCVILLDEIDKLSIGIQGDPASALLEVLDPEQNKNFRDHYLDLPFDISNVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQKYLWKKVLYKNGVTPYGIEFDKKAIVALIDSYSRESGVRGLEKVTDKLVRKIAIKIVRKESFPKIIQEKDLETFLGVPKFTDERMVRASVPGTALGLAWTSVGGATLLIEALFVKGKGGILLTGMLGKTMEESSNIALSYIKNLLYKEELFNNRMIHLHVPDGATPKDGPSAGITMASAILSLALNTKVKSGFGMTGELTLTGEVLAIGGLREKIVAAKRVGIHKIIYPKDNLQHLQEIPDYVKKGMYFFPVSRYEEVALLLFDEKVISKINPSFRENLKSIVNPTRKLSPKKKTTQKQKLSLSKQKGNNQKKK

lon

Lon protease

836 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

93.003 kDa

MTDHTKEHENTPSMGFLDGLVNSISQQPKAIEEEIKFDGALPVLPLRNTVLFPDVIVPIGVARQRSIALLESLAPNSPVVFLMQTDADIDAPTPDELHKNGSVGLVLRTLRMPDNSMSVIVQGVKRVVVEAFTQTEPYLAAKVTPKDEEELEGVEFDAYARTTKQLASKIIELSPNSPNEASYAIQSIENTRFLIHFIASNISVPAAEKQKMIEAEGMKARAERLIHFLNREVQVLELSKQIQTKVKTDMDRSQREFILRQQLKTIQQELGEQDAQMQDVEKLREAVEKKNLPEEVTSVVSKEIDKLSRIPQASPDYSVTRNYVDTILALPWGHFSETVINLHEAEKILNQDHYGLGKVKDRILEYLAVLKLKSNMKAPILCFCGPPGVGKTSLGRSIARALGRKFIRISLGGVRDEAEIRGHRRTYIGSMPGRIIQGIKTAGTSNPVFMLDEIDKIGADFRGNPSSALLEVLDPAQNNAFSDHYLEIPYDLSKVMFIATANTLDPIPVPLRDRMEIINLSGYTEYEKLHIAERYLIPRQLEEHGIRPEDVSFDALTTKKIINAYTREAGVRNLERQIANVCRVIAKDIVIRRESDQPDETPITVVTADLKKYLGMEQFYPDVSEPVMLSGVAVGLAWTPVGGDILFIESTVMKGTGRLILTGQLGDVMKESAQAALSYLKSCADYFKIPDEAFRYWDVHVHVPQGAIPKDGPSAGVTILTSLASIYTQRKVKPCIAMTGEITLRGRILPVGGIKEKVLAAKRAGITEILLPEKNEKDVKEALETNGGAFSDVSFKYFHEMDDLIDYVLEPAENGAPQFKVEDKDHTPETTGNESE

lon

Lon protease

836 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

93.003 kDa

MTDHTKEHENTPSMGFLDGLVNSISQQPKAIEEEIKFDGALPVLPLRNTVLFPDVIVPIGVARQRSIALLESLAPNSPVVFLMQTDADIDAPTPDELHKNGSVGLVLRTLRMPDNSMSVIVQGVKRVVVEAFTQTEPYLAAKVTPKDEEELEGVEFDAYARTTKQLASKIIELSPNSPNEASYAIQSIENTRFLIHFIASNISVPAAEKQKMIEAEGMKARAERLIHFLNREVQVLELSKQIQTKVKTDMDRSQREFILRQQLKTIQQELGEQDAQMQDVEKLREAVEKKNLPEEVTSVVSKEIDKLSRIPQASPDYSVTRNYVDTILALPWGHFSETVINLHEAEKILNQDHYGLGKVKDRILEYLAVLKLKSNMKAPILCFCGPPGVGKTSLGRSIARALGRKFIRISLGGVRDEAEIRGHRRTYIGSMPGRIIQGIKTAGTSNPVFMLDEIDKIGADFRGNPSSALLEVLDPAQNNAFSDHYLEIPYDLSKVMFIATANTLDPIPVPLRDRMEIINLSGYTEYEKLHIAERYLIPRQLEEHGIRPEDVSFDALTTKKIINAYTREAGVRNLERQIANVCRVIAKDIVIRRESDQPDETPITVVTADLKKYLGMEQFYPDVSEPVMLSGVAVGLAWTPVGGDILFIESTVMKGTGRLILTGQLGDVMKESAQAALSYLKSCADYFKIPDEAFRYWDVHVHVPQGAIPKDGPSAGVTILTSLASIYTQRKVKPCIAMTGEITLRGRILPVGGIKEKVLAAKRAGITEILLPEKNEKDVKEALETNGGAFSDVSFKYFHEMDDLIDYVLEPAENGAPQFKVEDKDHTPETTGNESE

lon

Lon protease

835 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.419 kDa

MTEDFPKILPLLVEEDTFLYPFMIAPIFLQNNASIKAVAYAKNNKSLVFIACQKDKLNDNEAPYYDVGVIGSVMREANMPNGRVKLLFNGIAKGRILEPAKENEQGFLEAQISPIEYLEYDKENIQAIVEVLKEKVITLANVSSLFPPDLIKALEDNDDPNRIADLIAAALHLKKDQAYSLFANNNTEQRLLDLIDIVIEETKTQKLQKEIKSKVHQKMEQTNKEYFLKEQLKQIQKELGTDKQRDEDLNQYYQKLESIKPFLKEEAFKEIKKQIDRLSRTHADSSDSATLQNYIETMLDVPFGQYGKKALDIKHVREQLDKDHYSLKRPKERIVEYFATMQLLEMRRKKKPEKKDKTKGTILCFYGPPGVGKTSLANSIAKAIERPLVRIALGGLEDVNELRGHRRTYIGSMPGRIVQGLIEAKKMNPVMVLDEIDKVDRSVRGDPASALLEILDPEQNTAFRDHYANFSIDLSQVIFIATANNIDRIPAPLRDRMEFISVSSYTPNEKEEIAKNYLIPQELEKHALKPSEVEISHECLKLIIEKYTREAGVRDLRRQIATIMRKVALKYLEDNPHQKGRTKKGKNEKSEDQKSEDQKSENQKSENKDFCVSITPNNLKEYLERMVFEIDPIDEENKIGIVNGLAWTPVGGDVLKIEVLKIRGKGELKLTGSLGDVMKESAIIAFSVVKVLLDNETLKVPKIPSETDAEGKKKKKVLKVYNAYDLHLHVPEGATPKDGPSAGIAMASVMASILCDRATRSEVAMTGELTLSGEVLPIGGLKEKLIAAFKAGIKTALIPVKNYERDLDEIPAEVRENLNIVAVKNIAEVLEKTLL

lon

Lon protease

835 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.242 kDa

MKKLPYIAIRNQLIAPYSTATVKIGRPNSLAAIQFAQTGFNGEIYIFYTKDNKMVDSIKKTSDLEEYGVKAKIKEIVEQGKLQNVVFEVEELVKVKEIYKELGKYSFTSDIFASVTEVEYSGNFDILSDYRSKAKMLIEKLSNLHDEIGSYIYGGRRGIKELEKAFSANTNISPLTHDSFNVDIWKIIDALTIEHSWKEYFAIINETNLEKNYELAINMLINAIKMGKLDEEVNSTMRGDLENQQRDFLLRERLRQIKKLLKDDEAGAKAIENMEDAEENARQYPDYVIEALKTEQNRLASMMPASPEANISKTYIDLITTLPWKKVSGELLDIDNVRKILDKHHYGLEKPKERILEFISVLTYTKKENEKNEYVPVKGEENRFIDKNLFVNKTGNFLKDRVNNIPILTLIGPPGTGKTTLAKSIAEALGRQFVKISLGGVKDESEIRGHRRTYVGALPGKIISGIKKAGVSNPVILLDEIDKMSSDFRGDPLSALLEVLDPEQNTNFQDHYLDLEYDLSKVLFIATANSFDSIPAPLYDRVEFLELSTYTLIEKTRIARTHLLSKILSLNALTEKQYQITDEVLAYIIKNYTRESGVRNLQRLLDSIARKIVVRILDKKVDKEFVIDKAIVREFLGPELYNEKGDETQPKAGVVNALAYTAYGGTSMTIEVTTFPTTAKGALNLTGQLKDVMRESATISLAYVRSNAEKFGIKDFDFENTSIHIHVPEGAIQKDGPSAGVTFTTAIISALSKKAVPNTIAMTGEITLRGKVLPIGGLKEKSLAASQIGIKTIFIPKDNEKNLIDVPEEVKKDIKFVPVEYYDEIFKYIFEAKNK

lon

Lon protease

835 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.306 kDa

MLEEPIDALETEFENALNSLEDNQLSKINGQLPEQVHVFPLLRRPFFPGMAAPLVIEPGPFYEVLKVVAKSDHKCVGLVLTRSEQAEIYKVGFSDLYQIGVLARVLRIIPMEQGGAQVILNMERRIKIEKPTSETKTLKANVSYIEDDPILTTELKAYAISILSTIKELLKLNPLFKEELQIFLGHSDFTEPGKLADFAVALTTASREELQDVLETFDIRKRIDKALILLKKELDISILQHNINQKIEATINKSQKDFFLREQLKTIKKELGIERDDKSLDREKFEARLKERVVPSDVMKVITEELEKLSVLDMQSAEYSVVRGYLDWLTTIPWGIYSQENHNLEEAEKILAHDHYGLEDIKQRILEFIGVGKLAKGVRGSIICLVGPPGVGKTSIGKSIARALNRKFYRFSVGGMRDEAEIKGHRRTYVGAMPGKMIQALKYCQTMNPVIMLDEVDKMGKSFQGDPASALLEVLDPEQNAEFLDHYLDVRCNLSEVLFIVTANVLDTIPEPLKDRMDILRLSGYIMQEKLEIAKKYLIPRNRKEMGLKALEVSFTQEALRSIINGYARESGVRNLENLLKKILRKLAVNIVREQEEHDKEQAKKKKSSRSKKPIAFVPTKHSITPSNLKDFLGKPVFTSDRFYERTPVGVCMGLAWTAMGGATLYIESIKVAGEKTVMKLTGQAGDVMKESAEIAWSYVHSSIHKYAPGYTFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLILDTPVLDNLGMTGELTLTGRVLPIGGVKEKLVAARRSGLKVLIFPKDNLRDYEELPEYIRKGITVHFVDHYDQVFKISFPNKHQMKLC

lon

Lon protease

833 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

94.358 kDa

MKYPFMATRGVITFIGNSSTIEVGRPLSLAAIDLAKSDFENKLVLIPQKNIKQNEIEFEKDLENVGILTKIKSIKILSNGNRKIIVEGVERIKLDSIEKDKNNNDIIANLSLYPVLKNENGSSETIIEKMQTSLNNIIESNLPLVANQELSKHESSERYTYILAHYLTMPFEKKFEIFAKKSLTEMLELIFSFLVELKNIQKLDVDLDKDIKKNLDSQQREYLLRERLKVIQKKLGDDENDEEEIEEKLNSKYGKEQYPEEVIKTIKNEKRRLKNMMSSSPEANTSRTYIEWLTNLPWRKVSVDKTNLVKSKEILDSYHYGLKEVKERIIEFLAVMINNNKKHPEDEKTKIQIPNSDYEINKNLFTKKNASDDTYSYKSSNNVPILALVGPPGTGKTSLAKAIAETLDRKFIKISLGGVKDEAEIRGHRRTYVGALPGKIIQAIKKAGVSNPVILLDEIDKMSSDYKGDPTSAMLEVLDPEQNVNFQDHYIELEYDLSKVLFIATANYYQNISAPLLDRVEIIELSSYTSLEKIRIARDYLIKKVLEQNSLEESQFKISDESLDFLIKHYTLEAGVRNLQRALDKLARKIVVKSLENKLEKDFVITSEEIVNLLGVIKYTDDFKENYERIGAVNGLAYTQYGGSTLSIEVTTFPNSKGGIKLTGQLKEVMQESAQIALAFVRSNAKKYEIDFNFEANQIHIHVPEGAVPKDGPSAGVTFTTAIISALKQIPVSHKVGMTGEITLRGKVLPIGGLKEKSLAAHKLGIKTVFIPNENNRNLVEVADEVKESIEFISVSDYDEIFENLFGKLSDNKKITSNSKIPKKDISKANPTH

lon

Lon protease

831 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

93.946 kDa

MTEDFPKILPLLVEEDTFLYPFMIAPIFLQNNASIKAVAYAKNNKSLVFIACQKDKLNDNEAPYYDVGVIGSVMREANMPNGRVKLLFNGIAKGRILEPAKENEQGFLEAQISPIEYLEYDKENIQAIVEVLKEKVITLANVSSLFPPDLIKALEDNDDPNRIADLIAAALHLKKDQAYFLFANNNTEQRLLDLIDIVIEETKTQKLQKEIKSKVHQKMEQTNKEYFLKEQLKQIQKELGTDKQRDEDLNQYYQKLESIKPFLKEEAFKEIKKQIDRLSRTHADSSDSATLQNYVETMLDVPFGQYEKKALDIKHVKEQLDNDHYSLKRPKERIVEYFATMQLLEMRHKKKPEKKDKTKGTILCFYGPPGVGKTSLANSIAKAIERPLVRIALGGLEDVNELRGHRRTYIGSMPGRIVQGLIEAKKMNPVMVLDEIDKVDRSVRGDPASALLEILDPEQNIAFRDHYANFSIDLSQVIFIATANNIDRIPAPLRDRMEFISVSSYTPSEKEEIAKNYLIPQELEKHALKPSEVDISHECLKLIIEKYTREAGVRDLRRQIATIMRKAALKYLEDNPHKKGRTKKSEDKDKKGGNEENEKRGESKDFCVSITPDNLKEYLERMVFEIDPIDEENKIGIVNGLAWTPVGGDVLKIEAVKIRGKGELKLTGSLGDVMKESAIIAFSVVKVLLDNETLKVPKIPSETDAENKKKKKVLKVYNAYDLHLHVPEGATPKDGPSAGIAMASVMASILCDRAIRSEVAMTGELTLSGEVLPIGGLKEKLIAAFKAGIKTALIPVKNYERDLDEIPTEVRENLNIVAVKNIAEVLEKTLL

lon

Lon protease

830 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.804 kDa

MTFDTNDDSIAKNSLAPYNQETEQQQEEGAMKINAGTEDDVQPQEIPSSIPILPLRDVVVFNYMIVPLFVGRERSIQAVESATTHGQHIFLCAQKDSQIENPTEEDLYSVGTVALILRLLKMPDGRLKALVQGISRARCLTIHNEDGYLTATVELLQEPQPTVKPTEQEALLRYAREQCEKILALRGIPTGEIMGVLSNVNEPGRLADLIAANLRLKTEEAQEILQCLEPIDRLHLVITHLTHEAEVATMQVKIQTSAREGMDKAQKDYFLREQLKAIRKELGDAIDADEEIEEVSSALNKAGLPAEVRKEVDKQLRRLSTMHADSAEAGVIRTYLDWIAELPWKKTSKDQLDIHKAKTILNEDHYGLVKIKDRILEYLSVRKLNPKSKGPILCFAGPPGVGKTSLGRSIAKSLGRKFQRISLGGMHDEAEIRGHRRTYIGAMPGRLIQAMKQAGTKNPVILLDEIDKLGNDFRGDPSSALLEALDPEQNHNFSDHYLNVPFDLSKVLFLCTANHLEHIPAALKDRLEIISLPGYTQQEKLAIARKYILPKQLKENGLKENELIISDTCLEKIIREYTREAGLRNMEREIGSLCRKVARKKAEGKKPPFRITTNQIEKFLGIPRFIDDDTEKTLPPGVALGLAWTPAGGEILYIEVSTVKGKGNLLLTGQLGDVMKESAQAALSYARSKASSLNISPDFAKSMDIHIHIPAGATPKDGPSAGVTLTTALISALTGKSVRGDLCMTGEITLRGRVLPVGGIKEKVLAGVARGLGHVIIPTKNTKDLEEIPQELKKKIKIHTVSHIDEVLPLAFSETIPVVTKKKQTKQPTS

lon

Lon protease

830 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.244 kDa

MIAENKDYVKPDVNTLPAVLPAVAIRDVVMFPGMSLPLSVSRSKSIAAINLALDSNKYVVAVAQKEAEVEDPKAEDIYRFGVLSEITQSLKMPDGSIKVFLQGIARVKIEHLDFNNIANSWFASVFYPADEKVSGPEVTALMRQLLDEFEEYATVSRRIAVEGVSFFRQIEDPSRLADTIASNIIVKTSDRQDVLEAVNPKDRLELLIKILANEVEIISLEEKIHSKVRAQIEKNQKEYYLNEQMKAIQKELSQKDDFQKEIDELRSKIKKNGLPKNAKESAEKELDRLAKMAPFSPESTVSRTYLDWLVNMPWNSSTNDILDLKKAKEVMDADHYGLDKPKERILEYLAVSKLTNSLKGPILCFAGPPGVGKTSLAKSIASAVGRKFVRMSLGGVRDESEIRGHRRTYIGSMPGRIIQGISKAKSNNPVFLLDEIDKMGSDWRGDPAAALLELLDPEQNKDFSDHYLDVPFDVSKVMFITTANSLSSIPVTLRDRLEIIDFSGYTEYEKEAIAQNHLIPRQMKEHGLKEGSLEIGLPAVKLIMRDYVREAGVRNFEREISTICRKAAKMYVENCGKTVTVTKDNLHDFLGVPRYTNFTTEENGVGISTGLAWTSVGGETLSIEASEISDGKGRIMLTGKLGDVMKESVHAALTYARSKGYGKGIDFNKTDFHIHFPEGAVPKDGPSAGTAVTTALISLLTKNPVKKNLAMTGEVTITGRVLPIGGVKEKFMAAYREGVKTILYPHTNEKDVSEVPEVIRKQLKLIPVKHMDEIVKIAFEKGEPKSSFKKSKTAPKKESAKKAAKSKKPAVKKPAVKKTKQVKKTAKKKK

lon

Lon protease

827 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.352 kDa

MNDETLREQTTAESEETSPTTPSPEPEVVETLPLIPLEGAVVFPYIVVSLTLDELGSASAEAAAREGRQVLLAARRPDAPADAPITDQLFNVGVVARIEQLGTLPNGASGVVVRGLVRAVLGEAVQTTPYLRFRFTRRPDVFERTPELEQLMVEVHAAIDAVLELRPGVTQEIRNFVRSIDDPGHLADNTGYSPDYTFAERQELLETFDVSERLRKVLMFYRKQFALLEVQAKLRQEVQESAARQQREFYLRQQLRAIQKELGEDTSEAAELDDLRQKLAAADLPEVARKEADRELSRLARINASSPEYQMVRTYLEWLAELPWNKYTGQPIDIAFARQVLDEDHHGLQKVKERILEYLAVKQRRAALGEENLRANREPILAFVGPPGVGKTSLGQSIARALGRSFVRMSLGGVRDEAELRGFRRTYIGSQPGRIIQELRRAGTADPVILLDEIDKLGIDYRGDPAAALLEVLDPEQNHTFTDHYLNLPFDLSRVLFLATANTWDTVPPALRDRMEVIELSGYIEDEKVQIAQIHLVPRQLRANGLRPEEAVVTEDAIRCIINEYTREAGVRNLERSIGAVLRKVARRLSEGEIDPANTPFVVDAAFVRAALGRPRFTNETRERIDQPGVAIGLVWTPVGGDIIFVEASAVEGKKELTITGQLGEVMRESAEAALTYVRSRARSLGIEPDFFETHAIHIHVPAGAVPKDGPSAGITMATALASAATGRLVRDDIAMTGEISLRGRVLPIGGIKEKALGAHRAGIRTVILPRRNLIDLDDLPPAVSAEMTFIPVDTLDEVLSIALLPPATTTDTLTVAQRSDVLTPAS

lon

Lon protease

827 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.352 kDa

MNDETLREQTTAESEETSPTTPSPEPEVVETLPLIPLEGAVVFPYIVVSLTLDELGSASAEAAAREGRQVLLAARRPDAPADAPITDQLFNVGVVARIEQLGTLPNGASGVVVRGLVRAVLGEAVQTTPYLRFRFTRRPDVFERTPELEQLMVEVHAAIDAVLELRPGVTQEIRNFVRSIDDPGHLADNTGYSPDYTFAERQELLETFDVSERLRKVLMFYRKQFALLEVQAKLRQEVQESAARQQREFYLRQQLRAIQKELGEDTSEAAELDDLRQKLAAADLPEVARKEADRELSRLARINASSPEYQMVRTYLEWLAELPWNKYTGQPIDIAFARQVLDEDHHGLQKVKERILEYLAVKQRRAALGEENLRANREPILAFVGPPGVGKTSLGQSIARALGRSFVRMSLGGVRDEAELRGFRRTYIGSQPGRIIQELRRAGTADPVILLDEIDKLGIDYRGDPAAALLEVLDPEQNHTFTDHYLNLPFDLSRVLFLATANTWDTVPPALRDRMEVIELSGYIEDEKVQIAQIHLVPRQLRANGLRPEEAVVTEDAIRCIINEYTREAGVRNLERSIGAVLRKVARRLSEGEIDPANTPFVVDAAFVRAALGRPRFTNETRERIDQPGVAIGLVWTPVGGDIIFVEASAVEGKKELTITGQLGEVMRESAEAALTYVRSRARSLGIEPDFFETHAIHIHVPAGAVPKDGPSAGITMATALASAATGRLVRDDIAMTGEISLRGRVLPIGGIKEKALGAHRAGIRTVILPRRNLIDLDDLPPAVSAEMTFIPVDTLDEVLSIALLPPATTTDTLTVAQRSDVLTPAS

lon

Lon protease

827 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.88 kDa

MFKNMTLLGTLIEHSDGLPLLETNMKNMHKDHNQDASLTLLASKYNVLFPGIYMPMTLENASIIRLVKKVYETGGIIGIVAQKKEDVEATSAQDIFTIGTTARILKLINLPDERVRILLQGEEKFQIEDVIAETPYLLASISRLKDKTSNTQSKHFKAVVSSIKETVAKLISLQPEFPTEIKLLLDNINDFNLLTYFLASGLDTDIKSKQKLLEIHDSKKRGTVLLKYLLKDLEVSKLRKKIQDKVHTDIEQLQHDFYIRRQIKVLQEELGENEFEDEIDELRAEGEKKQWPKEVADYFYKALDKAERLSPNSADYPVLISHAELMLELPWSVYTTDNMDLKMAKKVLDTEHYGLEKVKERLLEYLAVRKLTQNMKGPILCLYGPPGVGKTSLGKSIAKALNRKYVKVSLGGLHDEAEIRGHRKTYVGAMPGRIIKGIQNSGSSNPVFMLDELDKITDLRGDPAAALLEVLDPEQNQAFVDTFLEVPYDLSKVLFIATANQLDTIPPALRDRLEIIEINGYTIEEKLQIAKKYLFPKQRKENGLKATDLSIHDTAIVKVIESYTRESGVRELDRKLASLVRKVGKAMVLEEPYPKKIHKEDVISLLGIELFDQEMYQQTHLPGVAIGLAWTPVGGDILFIEAILSAGKGKLTLSGQLGDVMKESAMTAFTYLKANTNLLGIPDKVFESYDLHIHLPAGAVPKDGPSAGITLFAALASLYTQRKVKDKVAMTGEITLRGKVLPVGGIKEKILAAKRAGIKEVILSKENKKDIQEIKQKDIQDLKFHYVEFVEEVIQLALQPSKVEAAKDWSITKKRKQQPGIGHVSTL

lon

Lon protease

826 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.194 kDa

MAHTDTDDLVGLLDADDQNLDIPATLPMLPVRDVVVFTHMIIPLFVGRDKSVRAVDAAMAKDRFLFLATQMDGAVENPESDQIFKHGTAARILRVLKLPDGRVKVLVQGLAKAKIVRYTKKSDMFRVRIELLHEEDLGDLDMETEALMRNVKESCEKILGLRGELTPDVTMVLDGIDHPGRLADLVASNLNLKIEEAQSIFETIDPVQRLLAVNGFVSREVELSAMQARIQSSVRDEISKSQKDYFLREQMRAINRELGEMDEKTQEIKEYQDKIRKAKMPKEAKEEAERQLKRLEQMHPEAGEAPTVRTYLDWLVEVPWKKATKDTLDIKKAKEILEEDHYGLEKVKDRILEYLAVRKLNPKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFYRLSLGGIRDEAEIRGHRRTYIGALPGRIIQGLKHCKSNNPVFMMDEIDKIGADFRGDPSSALLEALDPEQNFAFSDHYLNVPFDLSSVMFITTANMTDTIPSALLDRMEVINLAGYTENEKVLIAQQYLVPRQVKENGLKPEDITISGNALLKMATEYTSESGLRNLEREIGTLCRKVSRKIAEGKKGPYQITASSLVKYLGLEKFLPEMDQEEPQIGLATGLAWTHWGGEALYIETTLMRGKGELVLTGQLGEVMQESARAALSYARTNEDELEIDPDLFDNFDIHIHVPAGAIPKDGPSAGIAMTTALVSALTERPVANDIAMTGEVTIRGRVLPIGGLREKSLGALRAGIKTIIIPEKNKKELSEVPQQVRRKLKYITVSHVNEVLEKALLPAEKKKAPPKKKPPKKAAKPKAKKTQPKAKTTEAADK

lon

Lon protease

826 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.194 kDa

MAHTDTDDLVGLLDADDQNLDIPATLPMLPVRDVVVFTHMIIPLFVGRDKSVRAVDAAMAKDRFLFLATQMDGAVENPESDQIFKHGTAARILRVLKLPDGRVKVLVQGLAKAKIVRYTKKSDMFRVRIELLHEEDLGDLDMETEALMRNVKESCEKILGLRGELTPDVTMVLDGIDHPGRLADLVASNLNLKIEEAQSIFETIDPVQRLLAVNGFVSREVELSAMQARIQSSVRDEISKSQKDYFLREQMRAINRELGEMDEKTQEIKEYQDKIRKAKMPKEAKEEAERQLKRLEQMHPEAGEAPTVRTYLDWLVEVPWKKATKDTLDIKKAKEILEEDHYGLEKVKDRILEYLAVRKLNPKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFYRLSLGGIRDEAEIRGHRRTYIGALPGRIIQGLKHCKSNNPVFMMDEIDKIGADFRGDPSSALLEALDPEQNFAFSDHYLNVPFDLSSVMFITTANMTDTIPSALLDRMEVINLAGYTENEKVLIAQQYLVPRQVKENGLKPEDITISGNALLKMATEYTSESGLRNLEREIGTLCRKVSRKIAEGKKGPYQITASSLVKYLGLEKFLPEMDQEEPQIGLATGLAWTHWGGEALYIETTLMRGKGELVLTGQLGEVMQESARAALSYARTNEDELEIDPDLFDNFDIHIHVPAGAIPKDGPSAGIAMTTALVSALTERPVANDIAMTGEVTIRGRVLPIGGLREKSLGALRAGIKTIIIPEKNKKELSEVPQQVRRKLKYITVSHVNEVLEKALLPAEKKKAPPKKKPPKKAAKPKAKKTQPKAKTTEAADK

lon

Lon protease

826 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.692 kDa

MSEEELNNRDTESKQEHDENNSNFEAGSAHMNLPVLPLREVIFFPGDYLPIFIGRKGSIQAMDKALAETSENTGRMLLIAQKNPKKEIPEGKDLYEVGVIAKIAEPKINLQDGGVKLMVIVECRARAVNFRKSEGVLEADVLPIEEEESDNVDIEAYRRAVVQNFEKCVKLSETIPDEIIGLLSQIDSTSRIADLVTASINLKLSVKQEILETVDLLERIKKVHALLEKELGVLQVKQQIKEKTESQIKKSHKVYLLNEQLKAITKELYDKEGEEYDELVDLEKKIGNGKLSAEAKEKVSKELKKLKNMVPMSAEATVVRNYVDWIISLPWKKKGKMITDIAASERILKASHYGIEKVKERIIEYLAVQNRTKSFKGSILCLLGPPGVGKTSLASAIAEATGRPFVRMSLGGIKDESEIKGHRRTYIGAMPGKIIQHMKKAKLSNPVFLLDEIDKMSSDFRSDPAFALLEVLDPEQNAHFVDHYLEVEYDLSDVMFVATANSLNMIPALLDRLEIIRLEAYSEEEKLQIAEHYLIGKLQREHGLKKSEWSISKEALKLLIRRYTRESGVRNLKRELANLMRKAVKKLGVQSGLKSIEVSVKNLKKYAGVEKYTFGTAEPENLVGMTTGLAYTQTGGDLIMIEAVLLPGKGEIRSTGKLGEVMQESVQAAYSFVCSNCNKFGFTSKFFKSKDVHLHVPEGATSKDGPSAGVAICTSIVSVMTGIPVRSNVAMTGEVSLRGKVMEIGGLKEKLLAAVRGGIKIVLIPASNEKDLENIPKSVKNAVRIIPVSTVSEALTFTLAEQPTPLAVDVWPDIPLSSTQQSEQRV

lon

Lon protease

825 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.97 kDa

MTQEMENENLSFTQQLRKDGFIKDIDTNPTCFDDTDSQNQLPIIFIPNTILLPHTDITLNLDKQHTDNLLHTVDDNNHGIILTPKKLEEGNGNVEFYDVGVILEIKSLTEDKENELLPEEYVLELKVKDKVYVNKILKKDGFFHAQYKILPEENTLTEDEITELNKNIDETVLEIAKFLPNTDKYTRKILGKLDTQDKLAEVFPFLKVPINKKQELLELDSVKIRALKVIQLLLEQKDAIGIQMELAKKLNKKMNETHKNTLLREQMKLIQEELNMTDDTPAHKTYRERIKDAQLPKEVEEAALEEVTKLERQGQNNAEENIIRNYLDTILQLPWHKEENPTIDIVKAKKQLNDDHYGLKKVKTRIIQHLTVLKMKKDKQGSILLFVGPPGTGKTSLGKSIAAALERPYVRVSLGGVNDESEIRGHRRTYLGALPGRIINGMKKAGKTNPVFVLDEIDKMTESLNGNPTSALLEVLDPEQNDSFSDNYLEVPYDLSDVFFIGTANSLQDIPGPLRDRLEIIELDSYTNTEKHHIADEHLIKEVLLEHGLTEDDLKITYDAIDCLIEKYTRESGVRGLKREIAAIARYVTEKIVVDNVERPYVVDENMLYDILGHEKSHYDKVPDSNPPGVVTGLAWTPIGGDILFIEAVLLPGEEKLKLTGQLGDVMKESAQIAQSLIKSRLATVLKDSDIEKRDIHIHVPAGSIPKDGPSAGVTLLTTIASLVTNTPVDSTLAMTGEISLRGKVLPVGGIKEKVIAAHRSGIKTVLLPEENMKDLDDVPCEVKDDMTFKPMKTVDEVLYEALGLKLPENKPLNISIDEINKVTP

lon

Lon protease

824 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.561 kDa

MNEPMSLFDDLPEEHDEPQEAPERRLPMVVLGEMVIMPHMTIPLQVPQGKSYRAMERAWEEDRDVLLIFVREHQLEGYKSNQPQNLPPIGVIAQLQEFAKLNDGTARVILEGQSRAQIIEAIQITPFYRVRCRPYTDPPVSGLEVEALMETVKQQVDEFVEHLGEVPQEAVQFVHRIDRPGHLADIVTWGPAFDFKDRLEVLNTLDPVERLRKVYLVLARQLELLKLRVKIQQDTKEVLDQSQREYFLREQLRIIRRELGEDEEGDDPIDELRRKIHELDAPEYVKNQALHELKRLAQQGMNNPESGVIRTYLDWILSLPWADEELPEISITEAQKVLDADHYGLEKVKERILEYLAVRKLAGDKMRSPILCFVGPPGVGKTSLGRSIARALGRKFVRTSLGGVRDEAEIRGHRRTYIGAMPGRIIQAMKNAKSKSPVYILDEVDKIGLDFRGDPTSALLEVLDPEQNNAFSDHYLEIPFDLSKVIFIATANQLDPIPLPLRDRMEIIEIGGYTEDEKLEIARGFLIPKQREFHGLTEDQIEFTEGAILKLIREYTREAGVRGLEREIASLCRKVARQVAEQTEANGELPPKFVIDEAAVVKYLGPERYTYGIAEEQDEVGVATGVAWTSAGGDILSIEVLPFKGKGQLQLTGQLGEVMKESAQTAVSYVRSRAADFGIDPNTFEETNIHIHIPEGAVPKDDPSAGITLTTALISALTGTPVRRDVAMTGEVTLRGKVLPIGGLKEKTLAAHRAGIRTFILPKENAKDISELPEKVRRELNLIPVSSMDEVLRIALSRMPTPANNQNGSHTNNRGQPSPAPAGT

lon

Lon protease

824 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.561 kDa

MNEPMSLFDDLPEEHDEPQEAPERRLPMVVLGEMVIMPHMTIPLQVPQGKSYRAMERAWEEDRDVLLIFVREHQLEGYKSNQPQNLPPIGVIAQLQEFAKLNDGTARVILEGQSRAQIIEAIQITPFYRVRCRPYTDPPVSGLEVEALMETVKQQVDEFVEHLGEVPQEAVQFVHRIDRPGHLADIVTWGPAFDFKDRLEVLNTLDPVERLRKVYLVLARQLELLKLRVKIQQDTKEVLDQSQREYFLREQLRIIRRELGEDEEGDDPIDELRRKIHELDAPEYVKNQALHELKRLAQQGMNNPESGVIRTYLDWILSLPWADEELPEISITEAQKVLDADHYGLEKVKERILEYLAVRKLAGDKMRSPILCFVGPPGVGKTSLGRSIARALGRKFVRTSLGGVRDEAEIRGHRRTYIGAMPGRIIQAMKNAKSKSPVYILDEVDKIGLDFRGDPTSALLEVLDPEQNNAFSDHYLEIPFDLSKVIFIATANQLDPIPLPLRDRMEIIEIGGYTEDEKLEIARGFLIPKQREFHGLTEDQIEFTEGAILKLIREYTREAGVRGLEREIASLCRKVARQVAEQTEANGELPPKFVIDEAAVVKYLGPERYTYGIAEEQDEVGVATGVAWTSAGGDILSIEVLPFKGKGQLQLTGQLGEVMKESAQTAVSYVRSRAADFGIDPNTFEETNIHIHIPEGAVPKDDPSAGITLTTALISALTGTPVRRDVAMTGEVTLRGKVLPIGGLKEKTLAAHRAGIRTFILPKENAKDISELPEKVRRELNLIPVSSMDEVLRIALSRMPTPANNQNGSHTNNRGQPSPAPAGT

lon

Lon protease

823 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.223 kDa

MEEIEDKEPRQENEELKIPDVLPLLPVRDVVVYPYMILPLFVGREISINAVDQALSRDRLIFLATQKEMGDEEPTPEGMYTVGTVAMIMRMLKLPDGRVKVLVQGLAKGLITEFVESKPAYTVRIERIVEPSVPEESLETEALMRAVKEQLTQIVSLGKAVSPEVLVIVENMQEPGSLADLIASNIGLKVDDAQALLEIIDPVQRLQKVNEHLNKEHELLDMQVKIQSAAKEEMGKSQREYFLREQLRAIQQELGETDPRSEELNELRKAIEQAKMPPVVEKEAFKQLGRLEQMHPDAAEAGMLRTFLDWMVELPWGKATKDVLDIKRARQILDEDHFYLEKIKERILEFLAVRKLRKKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGLKQAGSNNPVFMLDELDKLGADFRGDPSSALLEVLDPEQNHMFSDHYINLPFNLSNVMFIATANQIDTVPGPLRDRMEVIQLSGYTEEEKLEIAKRYLIPRQMKENGISEKEIVISDEAVRTIIAKYTREAGLRNLEREIGSVCRKVARKVAEGDGRRFRITPATVAKYLGPARFIREGEMEKNEVGIVTGLAWTPVGGEVLFVEATIMKGKGGLTLTGHLGDVMKESVQAALSYIRSKAKEFHLAEDFLSGYDIHVHVPAGAIPKDGPSAGVTMATALVSALTRVPVRKDVAMTGEITLRGKVLPIGGLKEKMLAAIRAGIKTIVIPEQNEKDLEEIPKHILKKVTVVSAKVIDDVLAVALETFPPPPPASEGKPAATVKAPPRRGIAAPRKGAMAGAKS

lon

Lon protease

823 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.725 kDa

MNVYMKEKTRVFCQNSFDDLDDNIGIVMPILTECDVDEDFTEGIEKVGDTIPILPLRNMVLFPGVALPVIIGRPKSMRLIKEAVHKKSLIGVVCQKEMGTEDPILEDLYTTGVIADIVRVLEMPDGSTTVILQGKKRFELNELTETDPYLSGKITVLEDTKPDKTDREFEALISTIKDLTIKMLGAVAEPPRDLIFSIKNNKNVLYVVNFSCSNIPSGSAEKQQLLLIGDLKERAYRLLFILNREYQLVELKASIQMKTHEDINQQQKEYFLQQQIKTIQEELGGNINELEIKELREKASRKKWPAEVAQVFEKELRKLERLHPQSPDYSVQTQYVQNIVNLPWNEYSKDNFNLSHAQKVLDRDHYGLEKVKERIIEHLAVLKLKGDMKSPIICLYGPPGVGKTSLGRSIAEALRRKYVRVSLGGLHDEAEIRGHRRTYIGAMCGRIIQNIQKAGTSNPVFILDEIDKITNDFKGDPASALLEVLDPEQNNAFHDNYLDIDYDLSKVMFIATANNLNTISQPLLDRMELIEVSGYIMEEKVEIAAKHLVPKQMDVHGLKKGSVKFPKKTLQVIVEAYTRESGVRELDKKIAKIMRKLARKVASDEPIPTSIKPEDLYEYLGAVEYSRDKYQGNDYAGVVTGLAWTAVGGEILFVESSLSKGKGSKLTLTGNLGDVMKESAMLALEYIHAHAAQFNINEELFENWNVHVHVPEGAIPKDGPSAGITMVTSLVSAFTQRKVKKNLAMTGEITLRGKVLPVGGIKEKILAAKRAGIKELILCKENEKDINEIKPEYLKGLVFHYVSDIQQVVDLALLREKVDNPLF

lon

Lon protease

821 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.363 kDa

MPDSTALPTTIPVCPVRGSVIYPTMVQHIDASRAISINAIEAAMSGEKVILIVSQRDKDVDDPKGEDLYDVGTACNVLRVRKNPDGTLQMLVSAVARVQVSAYQLGDYLTADIEPLDAGKSGGVELQALSRELKDKFETVASGGRINAESVQTINSKDDIGEMADHIAFNLDFKLEDKQAILEAANVTERLKKLLTLLDTEQEVQAVQAKIRAQVKEEIDKNQREYYLREQMKVIQKELQGGDEEEGDEAEAFRAKIDALGLNPEVKKEIDREVNRLARMHPDAAEASVIRTYLTWVTELPWNERSDDRLDVEEAAQVLDEDHYGLEKVKDRVLEFLAVRRLRKERAERGEISAEEVNKGPILVFTGPPGVGKTSIAQSIAKSLGRKYVRIALGGARDESDIRGHRRTYIGAMPGRIIQGIRTAGTKNPVILLDEVDKLGSSYQGDPSSALLEVLDPSQNQHFTDHYLGVPFDLSEVMFIATANYPEQIPAALMDRMEVIEFNSYIEQEKLEIAKRYLLPRQLLQNGLKPNQISFSDAALEKLISHYTREAGVRNLEREIGTVARKVARNIATGKTKRAKVTDKELEKYLGQPRHTPETENMEDMVGVSTGMFYTPVGGDILFVETSIMTGKGGGLLLTGQLGDVMKESARAALTYAKSNAERFHIDREKLDNSEIHVHVPAGAIPKEGPSAGGAMATSLISALTGIPARHDVAMTGEMTLTGRYLPIGGLKEKVLGARRAGIKHIILPKANERDINDIPLHLRSSMRFHPCETVDQVLDVALVGGLKALETPRTDSQVTPPADSGSKGRKTGRRSPEARA

lon

Lon protease

821 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.363 kDa

MPDSTALPTTIPVCPVRGSVIYPTMVQHIDASRAISINAIEAAMSGEKVILIVSQRDKDVDDPKGEDLYDVGTACNVLRVRKNPDGTLQMLVSAVARVQVSAYQLGDYLTADIEPLDAGKSGGVELQALSRELKDKFETVASGGRINAESVQTINSKDDIGEMADHIAFNLDFKLEDKQAILEAANVTERLKKLLTLLDTEQEVQAVQAKIRAQVKEEIDKNQREYYLREQMKVIQKELQGGDEEEGDEAEAFRAKIDALGLNPEVKKEIDREVNRLARMHPDAAEASVIRTYLTWVTELPWNERSDDRLDVEEAAQVLDEDHYGLEKVKDRVLEFLAVRRLRKERAERGEISAEEVNKGPILVFTGPPGVGKTSIAQSIAKSLGRKYVRIALGGARDESDIRGHRRTYIGAMPGRIIQGIRTAGTKNPVILLDEVDKLGSSYQGDPSSALLEVLDPSQNQHFTDHYLGVPFDLSEVMFIATANYPEQIPAALMDRMEVIEFNSYIEQEKLEIAKRYLLPRQLLQNGLKPNQISFSDAALEKLISHYTREAGVRNLEREIGTVARKVARNIATGKTKRAKVTDKELEKYLGQPRHTPETENMEDMVGVSTGMFYTPVGGDILFVETSIMTGKGGGLLLTGQLGDVMKESARAALTYAKSNAERFHIDREKLDNSEIHVHVPAGAIPKEGPSAGGAMATSLISALTGIPARHDVAMTGEMTLTGRYLPIGGLKEKVLGARRAGIKHIILPKANERDINDIPLHLRSSMRFHPCETVDQVLDVALVGGLKALETPRTDSQVTPPADSGSKGRKTGRRSPEARA

lon

Lon protease

821 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.617 kDa

MTDTGREGLQNREEGFELPLMSLREVVMFPRSIVPLFVGREASIKAIESAISDYGKKIFLVAQREPELEKPGPEDLFEVGTVSKILQLLRLPDGTIKVLFEGLYRARWDGTADAIIGADDAYPRVRVTRIEQESSEDDDEALVRATHEALDEYGKINKKLAQETLVAISALSDAARLADAIMPHLKVDYRRKQELLEVESGAERLEKVYELLQGEIAVASLEKRIKSRVKNQMERNQREYYLNEQIKAIHKEMGREDDPQAEVNELEARLAEKSMPEEAREKALREMKKLRQMPPSSAEYTVVRNYVDWILDLPWNTLKETEIDIDNARSILDADHYGLEKPKERILEYLAVQKLVNRLKGPILCLVGPPGVGKTSLAKSVAKATGREFVRLSLGGVRDEAEIRGHRRTYVGALPGKIIQSLKRVKHNNPLFCLDEIDKMSTDFRGDPSSALLEVLDPEQNSTFNDHYLDMDYDLSQVFFITTANSLHSIPLPLQDRMEIIRLPGYLETEKRRIAHDFLLPKQVEAHGLAASNLRISDNAVLEIIRSYTREAGVRNLEREIASVCRKAAMQVVEAGDKEKTLTVSRQNLGNFLGVKKYRHGEREDTSQVGVCTGLAWTEMGGELLVVETALMPGSGRVEITGKLGDVMTESAKAALSYLRSRSDLFGLRPDFHKEIDIHVHVPEGATPKDGPSAGITLATSMVSALLGIPVRNDVAMTGEITLRGRVLPIGGLREKLLAAHRGQIGKVLVPRENEKDLKEVPGEILKGLEIVFVDHVDEVLPQALMAQAESIFGGRTQSTPLYAKLRKDAQDGGATMPTAQ

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.844 kDa

MNSTNNTDSQNLDPNASEVEKLLDESAEAEEKTDDHTPPSELFILPLNKRPFFPGMAAPLLIEAGPHYEVLTLLAKSSQKHIGLVLTKKEDANTLKIGFNQLHRVGVSARILRIMPIEGGSAQVLLSIEDRIRIVKPVQDKYLKAKVAYHKENKELTEELKAYSISIVSIIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEVLETTDMHDRIDKALVLLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKDDHAVDLEKFMERLNKRDVPQYAMDVIQDEMDKLQTLETSSAEYAVCRNYLDWLTIVPWGIQTKEYHDLKKAESILNKDHYGLEDIKQRILELISVGKLANGMKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKLVQALKQSAIMNPVIMIDEVDKIGSSYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDSIPDPLLDRMEVLRLSGYILEEKLQIATKYLVPRARKEMGLSAQNVSFQPEALKHMINNYAREAGVRTLNENIKKVLRKVALKIVQNQEKNPSKKSRFTITPKNLQDYLGKPIFSSDRFYEKTPVGVATGLAWTSLGGATLYIESVQVPSSSGKADMHLTGQAGDVMKESSQIAWTYLHSALERYAPGRPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPVLNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNVLIFPEDNRRDYDELPAYLKKGLKVHFVTHYDDVFKIAFPGV

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.276 kDa

MDSTTNSDSPILDPNPEDVEKLLDESEEESEDQSTERLLPSELFILPLNKRPFFPGMAAPILIESGPYYEVLKVLAKSSQKYIGLVLTKKENADILKVSFNQLHKTGVAARILRIMPIEGGSAQVLLSIEERIRIIEPIKDKYLKARVSYHADNKELTEELKAYSISIVSVIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEVLETTNMHDRIDKALILLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKEDRAIDIEKFSERLRKRHVPDYAMEVIQDEIEKLQTLETSSAEYTVCRNYLDWLTIIPWGIQSKEYHDLKKAEIVLNKDHYGLDEIKQRILELISVGKLSKGLKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKMVQALKQSQAMNPVIMIDEVDKIGASYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDTIPDPLLDRMEILRLSGYILEEKLQIAKKYLVPKARKEIGLTASEVNFQPEALKYMINNYAREAGVRTLNGNIKKVLRKVALKIVQNQEKPKSKKITFKISSKNLQTYLGKPIFSSDRFYESTPVGVATGLAWTSLGGATLYIESVQVSSLKTDMHLTGQAGEVMKESSQIAWTYLHSALHRYAPGYTFFPKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLETPVVNNLGMTGEITLTGRVLGVGGIREKLIAARRSRLNILIFPEDNRRDYEELPAYLKTGLKIHFVSHYDDVLKVAFPKLK

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.965 kDa

MNSTNNTDSQNLDPNASEVEKLLDESAEAEEKVDDHTPPSELFILPLNKRPFFPGMAAPLLIEAGPHYEVLTLLAKSSQKHIGLVLTKKEDANTLKVGFNQLHRVGVSARILRIMPIEGGSAQVLLSIEDRIRIVKPIQDKYLKAKVSYHKENKELTEELKAYSISIVSIIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEILETTDMHDRIDKALVLLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKDDHAVDLEKFMERFNKRDVPQYAMDVIQDEMDKLQTLETSSAEYAVCRNYLDWLTIVPWGIQTKEYHDLKKAESILNKDHYGLEDIKQRILELISVGKLANGMKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKLVQALKQSQIMNPVIMIDEVDKIGSSYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDSIPDPLLDRMEVLRLSGYILEEKLQIATKYLVPRARKEMGLSAQNVTFQPEALKHMINNYAREAGVRTLNENIKKVLRKVALKIVQNQEKNLSKKSRFTITPKNLQDYLGKPVFSSDRFYEKTPVGVATGLAWTSLGGATLYIESVQVPSSSGKADMHLTGQAGDVMKESSQIAWTYLHSALERYAPGQPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPVLNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNILIFPEDNRRDYDELPAYLKKGLKVHFVTHYDDVFKIAFPGV

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.844 kDa

MNSTNNTDSQNLDPNASEVEKLLDESAEAEEKTDDHTPPSELFILPLNKRPFFPGMAAPLLIEAGPHYEVLTLLAKSSQKHIGLVLTKKEDANTLKIGFNQLHRVGVSARILRIMPIEGGSAQVLLSIEDRIRIVKPVQDKYLKAKVAYHKENKELTEELKAYSISIVSIIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEVLETTDMHDRIDKALVLLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKDDHAVDLEKFMERLNKRDVPQYAMDVIQDEMDKLQTLETSSAEYAVCRNYLDWLTIVPWGIQTKEYHDLKKAESILNKDHYGLEDIKQRILELISVGKLANGMKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKLVQALKQSAIMNPVIMIDEVDKIGSSYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDSIPDPLLDRMEVLRLSGYILEEKLQIATKYLVPRARKEMGLSAQNVSFQPEALKHMINNYAREAGVRTLNENIKKVLRKVALKIVQNQEKNPSKKSRFTITPKNLQDYLGKPIFSSDRFYEKTPVGVATGLAWTSLGGATLYIESVQVPSSSGKADMHLTGQAGDVMKESSQIAWTYLHSALERYAPGRPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPVLNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNVLIFPEDNRRDYDELPAYLKKGLKVHFVTHYDDVFKIAFPGV

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.276 kDa

MDSTTNSDSPILDPNPEDVEKLLDESEEESEDQSTERLLPSELFILPLNKRPFFPGMAAPILIESGPYYEVLKVLAKSSQKYIGLVLTKKENADILKVSFNQLHKTGVAARILRIMPIEGGSAQVLLSIEERIRIIEPIKDKYLKARVSYHADNKELTEELKAYSISIVSVIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEVLETTNMHDRIDKALILLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKEDRAIDIEKFSERLRKRHVPDYAMEVIQDEIEKLQTLETSSAEYTVCRNYLDWLTIIPWGIQSKEYHDLKKAEIVLNKDHYGLDEIKQRILELISVGKLSKGLKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKMVQALKQSQAMNPVIMIDEVDKIGASYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDTIPDPLLDRMEILRLSGYILEEKLQIAKKYLVPKARKEIGLTASEVNFQPEALKYMINNYAREAGVRTLNGNIKKVLRKVALKIVQNQEKPKSKKITFKISSKNLQTYLGKPIFSSDRFYESTPVGVATGLAWTSLGGATLYIESVQVSSLKTDMHLTGQAGEVMKESSQIAWTYLHSALHRYAPGYTFFPKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLETPVVNNLGMTGEITLTGRVLGVGGIREKLIAARRSRLNILIFPEDNRRDYEELPAYLKTGLKIHFVSHYDDVLKVAFPKLK

lon

Lon protease

819 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.965 kDa

MNSTNNTDSQNLDPNASEVEKLLDESAEAEEKVDDHTPPSELFILPLNKRPFFPGMAAPLLIEAGPHYEVLTLLAKSSQKHIGLVLTKKEDANTLKVGFNQLHRVGVSARILRIMPIEGGSAQVLLSIEDRIRIVKPIQDKYLKAKVSYHKENKELTEELKAYSISIVSIIKDLLKLNPLFKEELQIFLGHSDFTEPGKLADFSVALTTATREELQEILETTDMHDRIDKALVLLKKELDLSRLQSSINQKIEATITKSQKEFFLKEQLKTIKKELGLEKDDHAVDLEKFMERFNKRDVPQYAMDVIQDEMDKLQTLETSSAEYAVCRNYLDWLTIVPWGIQTKEYHDLKKAESILNKDHYGLEDIKQRILELISVGKLANGMKGSIICLVGPPGVGKTSIGRSIAKVLHRKFFRFSVGGMRDEAEIKGHRRTYIGAMPGKLVQALKQSQIMNPVIMIDEVDKIGSSYHGDPASALLEVLDPEQNKDFLDHYLDVRVDLSNVLFILTANVLDSIPDPLLDRMEVLRLSGYILEEKLQIATKYLVPRARKEMGLSAQNVTFQPEALKHMINNYAREAGVRTLNENIKKVLRKVALKIVQNQEKNLSKKSRFTITPKNLQDYLGKPVFSSDRFYEKTPVGVATGLAWTSLGGATLYIESVQVPSSSGKADMHLTGQAGDVMKESSQIAWTYLHSALERYAPGQPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPVLNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNILIFPEDNRRDYDELPAYLKKGLKVHFVTHYDDVFKIAFPGV

lon

Lon protease

818 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.809 kDa

MSIGRAVNFNSTVLPVLPLRDVVIFPNIMLPLFVGREKSVHALEYAISSSSHQNEIFLIAQKDGSIDNPEPENLYEVGVLANIIQPLIKLPDNAVKVMIHGVRRGRVIEYISSHTLLQARVALDGHYEYGENEDNIDLEALRRSVIDAFDNWCKLSKKSRPEIIIDPIDQVKEVNQIVDMIASHLNIKVSDKQNILEVYNPKERLKKVFALIEREISILSAQNRLYKTIKSQVESTQKVYYLNEQLKAIQKELGEFENGDEGNILNEFEKKINETKLSEEAKEKAITDLKRYKKMNPISPEATVISSYLHWLLDLPWGKYKDAKINLNAAKKILDENHYGIEKVKDRIIEFLAVLKRVKEIKGPILCLVGPPGVGKTSLAKSMAKAVGRDFVRISLGGIRDESEIRGHRKTYIGSMPGKIIQHMKKANSCNPLFLLDEIDKMGSDSRGDPASALLEVLDTEHNKHFTDHYLEVEFDLSSVMFVATANSLNLPHPLRDRMEIIQLSGYTEDEKISIATHHLIPKLKKEHGLHQKEWEITNEALYELIRLYTRESGVRSMERELAKLMRKAVKAILTDKNKKISVETGNLQDYLGVRKYTFGIAENESLVGIVTGLAYTETGGDILMIESVLIPGKGEIKYTGKLGEVMQESIKAAYSYVRSNCLFFGIKPEKFQNNDIHLHVPEGAVPKDGPSAGSAVCTSIVSLMTNIPVNKSVAMTGEVTLRGRVLAIGGLREKLLAALRGSIKTVIIPSENEKDMQEIPANIKEEINVIFAENIDEVIKVALMHPITSIDDNNEISVSTSIENKDNTFPSSETLKH

lon

Lon protease

817 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.649 kDa

MAQPKIPEYKANGTTDKLPETVPIMPLSDGVLFPKMIIPVVITQNEYMTLIDEVMSGNRLVALITPKSGERKSDYGPGDLSPIGTLALILKMAKPDESRIHLMLQGISRIRTKNFIKTDPYLEAAFAQITENEKKDKETEGLMSNISNVYQELVRISPAIPNELGAMAVTIDEPGSLADMVASTINSSTEEKQNILETLDVKLRLKKVTRQLNHQLEILKLGDKIQSQIKEDMDKQQKEFYLRKQLKAIREELGEKEEGNVEAEEYRTKIEEGNLPEEAYKAATRELERFSRMHPSSSEYTVSSTYLDWLTTLPWDKQTEDHLDIKKARAILDKDHFGLEKPKKRILEYLAVRKLNPDSKGPILCFLGPPGTGKTSLGRSIARALGREFIRISLGGVRDEAEIRGHRRTYVGALPGRIIQEIRKAGTNNPVFMLDEIDKVGADFKGDPSSALLEVLDPEQNFSFADHYLDVSFDLSRVMFVATANVIDTIPPALRDRMEVIGLRGYTLEEKVKIARQYLIPRQRKENGLAAKHISFSQSAIRHIISDYTREAGLRNAEREIASVCRGVAAKIAEGKKVSGAIKPEDLYEYLGPVRFTSETGENALTPGVVMGLAWTPVGGEILFIEATSMKGKRGLTLTGQLGDVMKESATAALSFIRAHARDYDIDEDFFDKYDFHIHVPSGAIPKDGPSAGVTMLTALVSLLTGRKVKKGLAMTGEITLRGKVMPVGGIKEKVIAAHRAGIKEVILPRPNKKDLEEIPAKVKSAMKFHFAEKMGDVLELALNGNGATKKKKKTPAKSKKSTKPAAKKTAARKSRK

lon

Lon protease

817 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.649 kDa

MAQPKIPEYKANGTTDKLPETVPIMPLSDGVLFPKMIIPVVITQNEYMTLIDEVMSGNRLVALITPKSGERKSDYGPGDLSPIGTLALILKMAKPDESRIHLMLQGISRIRTKNFIKTDPYLEAAFAQITENEKKDKETEGLMSNISNVYQELVRISPAIPNELGAMAVTIDEPGSLADMVASTINSSTEEKQNILETLDVKLRLKKVTRQLNHQLEILKLGDKIQSQIKEDMDKQQKEFYLRKQLKAIREELGEKEEGNVEAEEYRTKIEEGNLPEEAYKAATRELERFSRMHPSSSEYTVSSTYLDWLTTLPWDKQTEDHLDIKKARAILDKDHFGLEKPKKRILEYLAVRKLNPDSKGPILCFLGPPGTGKTSLGRSIARALGREFIRISLGGVRDEAEIRGHRRTYVGALPGRIIQEIRKAGTNNPVFMLDEIDKVGADFKGDPSSALLEVLDPEQNFSFADHYLDVSFDLSRVMFVATANVIDTIPPALRDRMEVIGLRGYTLEEKVKIARQYLIPRQRKENGLAAKHISFSQSAIRHIISDYTREAGLRNAEREIASVCRGVAAKIAEGKKVSGAIKPEDLYEYLGPVRFTSETGENALTPGVVMGLAWTPVGGEILFIEATSMKGKRGLTLTGQLGDVMKESATAALSFIRAHARDYDIDEDFFDKYDFHIHVPSGAIPKDGPSAGVTMLTALVSLLTGRKVKKGLAMTGEITLRGKVMPVGGIKEKVIAAHRAGIKEVILPRPNKKDLEEIPAKVKSAMKFHFAEKMGDVLELALNGNGATKKKKKTPAKSKKSTKPAAKKTAARKSRK

lon

Lon protease

817 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.375 kDa

MSNHKILTIDNLSLQEFDSEAELIPLLTPEDEEEMNNEELPVSLPILPLRNTVLFPGVVIPISAGRDKSIKLINDANAGGKIIGVVSQINEEDEDPSKDDIHKIGTVARILRVLKMPDGNVTVILQGKKRFEIDEVVSEEPYMTASIKEVSEERPDENDSEFTAILDSVKELAIQIIKESPNIPSEATFAIKNIESQSFLINFVSSNMNLSVKEKQGLLSINGLKERALETLRYMNVELQKLELKNDIQSKVRFDLDQQQREYFLHQQMKTIQEELGGVSQEEEMDEMGQKAKTKKWDEKTQKHFEKELSKMRRMNPQSPDFGIQRNYLELFLELPWGEYSKDKFDLKHAQKVLDKDHFGLDEVKKRMIEHLAVLKLRNDMKSPIICLTGPPGVGKTSIGRSVAEALGREYVRISLGGLRDEAEIRGHRKTYIGAMPGRIIQSLKKAGTSNPVFILDEIDKLSSGNSGDPSSALLEVLDPEQNNAFYDNFLEMGYDLSKVMFIATSNNMAAIQPALRDRMEVIKMSGYTIEEKVEIAKRHLFPKQLEAHGLTSKDLTIGKKQLEKIVEGYTRESGVRNLETKIAQVIRNAAKAVAMEEEYNKKVTDEDIVKVLGVPRLERDKYENNDVAGVVTGLAWTSVGGDILFIESLISEGKGALTITGNLGNVMKESATIALEYIKANAKKLGLAIELFQKYNIHLHVPEGATPKDGPSAGIAMLTSLVSLLTQKKVKKSLAMTGEITLRGKVLPVGGIKEKILAAKRAGIKEIILCHENKSDIDEIKEEYLEGLTFHYVKEMSEVLAIALTDQNVKNAKTLK

lon

Lon protease

816 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.252 kDa

MKSREIEYFMEEIKDTVSKEKKRSKNSGGILPHFDKPVRVPLIAVPSHPVFPSMFIPIVIVSDIDMKAVDYVIKGNGIISLFVLRDKFLEKSGNNKDGKLTINYQKDIYSVGVTAKIVKKINLPDGGYNIFVSTIDRVKFVKVVLNEDFPIIEVDYLKQIPIKKYDVNLKAIYSSILLKTKEIFSHRKMPEFQLNMVNIEDKGRLCDVVAGMIASSKESHQEVLETLSVKDRLKKVLELLYEELNLIEIQNKIAKGIQEKLEKQQKEFFLKEQLKAIKTELGVGDEKNSEFLKMKSKIDALALKGEALDAVGRELEKFSFLERHSSEYIVVRNYLELITNLPWEDTKVDFDKFNLQRAEKILDKTHYGMREVKDRILEYISVLKLRKSQKGAIMLLVGPPGVGKTSIGAAIAEVLNTKFFRFSVGGIRDESEIKGHRRTYVGALPGKIIQGLRITKTNSPVFLIDEIDKVSSSHYGDPFSVLLEVLDPEQNVNFRDHYLDLPFDISNVFFILTANSLETIPTPLLNRMEVIQLSGYVDDEKIEIARKYLIPKVLKENGVDKDSLKFQSSSLVQIAREYARDNGLRNFEKYLKQIVRKIARKLVEDQSVKAYQISKENLEEYIGIPVFRKEKFLDKAMSPGMVMGLAWTNYGGSTLIIETVKTESKSPGIKLTGRLGDVMKESANIAFTYVNSISNELKVHKSFFEKYMIHLHIPEGATPKDGPSAGITIASAFISLALNKTVRPNLAMTGELSLTGNVMAIGGLKAKIIAAKRNGVEHIIIPKANKVDLDDIPINIKNGINFHLVDSMKEVIKLLF

lon

Lon protease

816 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.91 kDa

MSKSDQEHTTTEPTIVAEEELRIPELLPLLPIRDVVVYPFMIIPLFVGREMSIKAVDQALAGDRMIMLATQHDIGDEDPTPDKIYNVGTVAMIMRMLKLPDGRVKILVQGLVKARIAEFVEFKPFHTVRIERLVEPVAVDNLETEALMRTVREQLAKIAELGKQISPEVMVILENITDPGSMADLIASNLGLKLSEAQMLLEIEDPVRRLTKVNDLLAREHEMLSVQAQIQNAAREEMGKNQKEYYLREQMKAIQQELGDHDGKEELEELRKAIETARMPENVEKEALKQLGRLERMHGDSGEAGVIRTYLDWLIEIPWSKTTRDSLDIIRAKKILDEDHSYLDKVKERILEFLAVRKLNKQMKGPILCFVGPPGVGKTSLGKSIARALNRKFVRISLGGVRDEAEIRGHRRTYLGALPGRIIQGMKQAGTRNPVFMLDELDKLGYDYKGDPSAALLEVLDPQQNNAFSDHYVNLPYDLSNVLFVATANHSDPIPSALFDRMEVINIPGYTEEEKLEIAIRYLVPRQMKDNGLKAKHIVFEEEALKEIIAKYTREAGLRNLEREIGNVCRKVARKIAEGHKRQIRVTPAAVATFLGAAKFLRDDEMDKNEVGVVNGLAWTSVGGEVLHIEATTMAGKGGMALTGQLGDVMKESVQAALAYIRSHGSEFHINPDWFQENEIHVHVPAGAVPKDGPSAGCAMATALISVLTKVPVKKDVAMTGEISLRGKVLPIGGLKEKILAAVRAGMKMVIIPEQNRKDLEDIPKAMQKKVKIVPVKEIDEVLKLALEKFPIPAPKGKAKPATPKVVVRPSKEISA

lon

Lon protease

814 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.615 kDa

MANEAHNIEHTDPEFRDDSADARTLPLLPVRDTVLFPHAVLPLTVGRESSVQLINSLGEDKTIVVVAQREARVDSPQPSDLFAIGSLAVVHKVVKMPNQSLFVFAEGLERVRVTEYVQLNPYMRATVETVPEAFPPKSAEIEALQRNVLTLFQQIVTGSPTLSDELSTVAMNIEEPGRLVDFVASSLPSLSTKDKQEILETADVQIRLDKINQHLAKELEVQQLRNKIQSEVQDRVQQTQREYYLREQLKAIQKELGEQDDSTRDADELREKVEAAGMPDDVKKEALKELGRLARMSPMAADYSVTRNYIEWLAVLPWQKSSGAGEIDIPKAKDILDEDHYDLQKVKDRILDYLSVRRLKPNMKGPILCFSGPPGVGKTSLGKSIARALGRKFVRISLGGVHDEAEIRGHRRTYIGALPGQIMQGIRRAETNDPVFMLDEIDKVGRDFRGDPSAALLEALDPEQNNSFRDNYLDVPFDLSKVLFITTANQLDPIPEPLRDRMEIIDLQGYSEEEKVHIAFRYLIPRQEEENGITKDMIEFSEEAVRRIIRHYTREAGVRNLERNIGTVCRKLARRIAEGKTEKLAVTPQTITEMLGGEKVRVDTEIAERTKRAGVVVGLAWTPAGGDILFVEATTMKGKGGFTMTGQLGDVMRESMQAALSWVKSNAGKLGIDEEFFEKHDIHIHVPAGAIPKDGPSAGVTMVTALVSLLTDKPLRPLTAMTGEITLSGNVLPIGGVKEKTLAAKRAGVKTIILPSENKMNMDEDLTPEQLQGIEVHYVKTIDEVLEIALPSNKAEEKQDARTRAEVLNEVPAV

lon

Lon protease

813 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.748 kDa

MLDTEPVDMIPLITPEEEAEMDKEEFPSVLPILPVRNIVLFPGVVLPITVGRQKSIRLVKKFYKGDRTIGVVAQENQKSEEPSFQDIFKVGTVAKILRMFVLPDGNTTIIIQGKRRFKIEEQVQDEPFMQAKVSMLKDIHPDMSKKEVKALLQSVKESATKILKMNPEIPQDAQIAINNIESENFLTHFLSSNINAELKDKQKLLEFDDAVERATWLLQLMDKDIQMLEIKREIHTKVHTDIDQQQRDYFLRQQIKVLQDELGDFSSEQEFERLKEKALTKKWSDKVRAHFDKEMSKLQRVNPMAPDYPVTFNYLELLVDLPWGENSTDNFDLVRAKEILDEDHFGLTKVKQRILEYLAVLKLKNNMKAPILCLYGPPGVGKTSLGKSIAKALDRKYIRMSLGGVHDESEIRGHRKTYIGAMPGKIIQGIKRSETSNPVFILDEIDKISKDFRGDPSSALLEVLDPEQNSSFMDNFLEVEYDLSKVLFIATSNALDTIQPALRDRMEIIEINGYTLEEKIQIAKKYLIPKQKEEHGLKAKDISFTDAAIVKIIEDYTRESGVRNLERKIGAVVRNIAVAIAMETAYTKKIQPAQVREILGSEDFEKDTYQQDDLAGIVTGLAWTPYGGEILTIESIISKGKGKLTLSGQLGDVMKESASAALSLLRANVDAIGIDHRVFDHFDLHVHVPAGATPKDGPSAGIALYTSLASTFTQRKIKPALAMTGEITLRGKVLPVGGIKEKILAAKRAGIKEIILSKKNKKDIEEIHPPDIADLKFHFVETADEVLAIALLKQKIKKPFNLEVPEEPKKKDK

lon

Lon protease

813 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.748 kDa

MLDTEPVDMIPLITPEEEAEMDKEEFPSVLPILPVRNIVLFPGVVLPITVGRQKSIRLVKKFYKGDRTIGVVAQENQKSEEPSFQDIFKVGTVAKILRMFVLPDGNTTIIIQGKRRFKIEEQVQDEPFMQAKVSMLKDIHPDMSKKEVKALLQSVKESATKILKMNPEIPQDAQIAINNIESENFLTHFLSSNINAELKDKQKLLEFDDAVERATWLLQLMDKDIQMLEIKREIHTKVHTDIDQQQRDYFLRQQIKVLQDELGDFSSEQEFERLKEKALTKKWSDKVRAHFDKEMSKLQRVNPMAPDYPVTFNYLELLVDLPWGENSTDNFDLVRAKEILDEDHFGLTKVKQRILEYLAVLKLKNNMKAPILCLYGPPGVGKTSLGKSIAKALDRKYIRMSLGGVHDESEIRGHRKTYIGAMPGKIIQGIKRSETSNPVFILDEIDKISKDFRGDPSSALLEVLDPEQNSSFMDNFLEVEYDLSKVLFIATSNALDTIQPALRDRMEIIEINGYTLEEKIQIAKKYLIPKQKEEHGLKAKDISFTDAAIVKIIEDYTRESGVRNLERKIGAVVRNIAVAIAMETAYTKKIQPAQVREILGSEDFEKDTYQQDDLAGIVTGLAWTPYGGEILTIESIISKGKGKLTLSGQLGDVMKESASAALSLLRANVDAIGIDHRVFDHFDLHVHVPAGATPKDGPSAGIALYTSLASTFTQRKIKPALAMTGEITLRGKVLPVGGIKEKILAAKRAGIKEIILSKKNKKDIEEIHPPDIADLKFHFVETADEVLAIALLKQKIKKPFNLEVPEEPKKKDK

lon

Lon protease

813 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.309 kDa

MAEEEKIRQTIQELPLLPLRGIIVFPYMVMHLDVGRERSVNAIEEAMAQDRIIFLATQKEAQTDQPGAEDIYQIGVIAEIKQLLKLPGGTIRVLVEGLARAEILEYIDMEPLIRVRVREHIEPDVKSNAVEALMRSLINQFEQYVKISKKIPPETFVSVVAVEDPGRLTDTISSHLTLKTQDKQRILEALDVTERLEILTEILAREMEILELERKINVRVRKQMEKTQKEYYLREQIKAIQKELGEKEDRQAEGEDLRNKIAKAKLPKEVEEKALREVERLEKMPPMVAEATVVRNYLDWLLALPWAKQTKDRLDIDKAEAILNEDHFGLDKVKERIIEYLAIRKLAQKMKGPIICFVGPPGVGKTSLARSIARALERKFVRLSLGGVRDEAEIRGHRRTYVGAMPGRLIQGLRTAGSKNPVFLLDEIDKMSMDFRGDPASALLEVLDPEQNSTFSDHFIEVPFDLSKVLFITTANGMHNIPRPLLDRMEVIYIPGYTEEEKTRIALDHLVPKQLKEHGLKKEQVQISENTVRRLIREYTREAGVRNLEREIASLCRKSARAIVKNPERRLSISAGNLPSYLGIPRFRYGLAEAESQVGVATGLAWTETGGDTLAIEVAHMPGKGNLALTGKLGDVMKESAQASLTYVRSRARELGIADNFHQNTDIHIHVPEGAIPKDGPSAGITIATALTSALSRRPVRREVAMTGEITLRGRVLPVGGIKEKMLAANRAGCTTVILPAENKKDLEEVPANVKKKLRFVLVEHMDQVIREALLEPVPVQAPEPPETIPAAIETSVPVYQGMLEETPPGLQT

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.461 kDa

MPTEEHQTYRELPMLPLRGVLVFPYTVIHLDVGRKKSINAIEDAMLGSKEIFLATQKEAQTDEPDEEDIYEVGTVAEIRQILKMPGGTMRVLVEGLFRAEINAYLANDPYMKVRVEELRDKKIKSPELEALMRNLVGQFEQYVRMSKKIPPETVVSVVAIEEGGRLADVIASHLNLRINEKQRILELSDINKRLNYLCELLAKEMEVLELERKINIRVRKQMEKTQKEYYLREQIKAIQKELGEKDERSSEVEEFRERIKKANMPKDAEEKAFKELERLEKMPPMVAEAVVVRNYLDWILSLPWSLETRDRLDLKAAEAILDEDHYGLEKPKERILEYLAIRKLAKKMKGPILCLVGPPGVGKTSLGKSVGRSLGRKFIRMSLGGIRDEAEIRGHRRTYVGSMPGRILQGMKTAGSKNPVFLLDEIDKMTMDFRGDPASALLEVLDPEQNYIFSDHYLEIPFDLSKVMFITTANSVFNIPRPLLDRMEIIEITGYTEEDKVHIATDYLVPKQIKEHGLKESNITFSEGTLRRIIREYTREAGVRNLERQIASICRKVARQVVEDKDTFVHVASNSLNRFLGAGRYRYGVAESENQVGVATGLAWTESGGDILSIEVALLKGKGNLTLTGKLGEVMKESAQAALTYVRSKADELGINDEIRDKYDVHIHIPEGAIPKDGPSAGITLATALASAMSGLPVRSDVAMTGEITLRGRILPIGGVKEKILAAHRAGIAKVLLPVENKKDLAEIPAPVKRKIKLVLVSHMDEVLEETLLKLEAIQPGEDFPGVLLNPELVGENLNQDRVEPEANKDLC

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Required for wild-type virulence during the initial stages of infection in the mouse model, but not essential for the establishment and maintenance of chronic infection in this host.

Belongs to the peptidase S16 family.

89.919 kDa

MTGIEQKTPVGGSETGGADGLYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGVDKQILLATQKNAADDDPAPDAIYEIGTIANVLQLLKLPDGTVKVLVEGTARAKISKFTDREDYHEAYAAALQEPEEDAVEIEALARSVVPDFENYVKLNKKISPEVVGAASQIDDYSKLADTVASHLAIKIPEKQEMLSVLSVRERLEKALSFMEAEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEVAEIEERITKTKLSKEAREKALAELKKLRSMSPMSAEATVVRNYLDWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVEYLAVQARSTKIKGPILCLVGPPGVGKTSLARSIAKATGREYVRMSLGGVRDEAEIRGHRRTYIGSMPGKVIQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSAMLEVLDPEQNATFMDHYLEVEYDLSNVMFVTTANTMNIPVPLLDRMEIIRIAGYTEDEKLEIAKRHLLPKAIKDHALQPKEFSVTEDALRNVIRHYTREAGVRSLEREVMTLARKAVTEILKTKKKSVKITDKNLSDYLGVEKFRFGQIDGEDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGIAMVTAIVSVLTGIPVRKDIAMTGEVTLRGRVLPIGGLKEKLLATLRGGIKKVLIPEENAKDLAEIPDNVKNNLEIVPVSRVGEVLKHALVRQPEPIEWTEQENPTAVPPVEDEAGASLAH

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.919 kDa

MTGIEQKTPVGGSETGGADGLYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGVDKQILLATQKNAADDDPAPDAIYEIGTIANVLQLLKLPDGTVKVLVEGTARAKISKFTDREDYHEAYAAALQEPEEDAVEIEALARSVVPDFENYVKLNKKISPEVVGAASQIDDYSKLADTVASHLAIKIPEKQEMLSVLSVRERLEKALSFMEAEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEVAEIEERITKTKLSKEAREKALAELKKLRSMSPMSAEATVVRNYLDWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVEYLAVQARSTKIKGPILCLVGPPGVGKTSLARSIAKATGREYVRMSLGGVRDEAEIRGHRRTYIGSMPGKVIQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSAMLEVLDPEQNATFMDHYLEVEYDLSNVMFVTTANTMNIPVPLLDRMEIIRIAGYTEDEKLEIAKRHLLPKAIKDHALQPKEFSVTEDALRNVIRHYTREAGVRSLEREVMTLARKAVTEILKTKKKSVKITDKNLSDYLGVEKFRFGQIDGEDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGIAMVTAIVSVLTGIPVRKDIAMTGEVTLRGRVLPIGGLKEKLLATLRGGIKKVLIPEENAKDLAEIPDNVKNNLEIVPVSRVGEVLKHALVRQPEPIEWTEQENPTAVPPVEDEAGASLAH

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.896 kDa

MTGIEQKTPVGGSETGGADGLYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGVDKQILLATQKNAADDDPAPDAIYEIGTIANVLQLLKLPDGTVKVLVEGTARAKISKFTDREDYHEAYAAALQEPEEDAVEIEALARSVVSDFENYVKLNKKISPEVVGTASQIDDYSKLADTVASHLAIKIPEKQEMLSVLSVRERLEKALSFMEAEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEVAEIEERITKTKLSKEAREKALAELKKLRSMSPMSAEATVVRNYLDWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVEYLAVQARSTKIKGPILCLVGPPGVGKTSLARSIAKATGREYVRMSLGGVRDEAEIRGHRRTYIGSMPGKVIQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSAMLEVLDPKQNATFMDHYLEVEYDLSNVMFVTTANTMNIPGPLLDRMEIIRIAGYTEDEKLEIAKRHLLPKAIKDHALQPKEFSVTEDALRNVIRHYTREAGVRSLEREVMTLARKAVTEILKTKKKSVKITDKNLSDYLGVEKFRFGQIDGEDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGIAMVTAIVSVLTGIPVRKDIAMTGEVTLRGRVLPIGGLKEKLLATLRGGIKKVLIPEENAKDLAEIPDNVKNNLEIVPVSRVGEVLKHALVRQPEPIEWTEQENPTAVPPVEDEAGASLAH

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.795 kDa

MTGIEQKTPVGGSETGGADGLYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGVDKQILLATQKNAADDDPAPDAIYEIGTIANVLQLLKLPDGTVKVLVEGTARAKISKFTDREDYHEAYAAALQEPEEDAVEIEALARSVVSDFENYVKLNKKISPEVVGAASQIDDYSKLADTVASHLAIKIPEKQEMLSVLSVRERLEKALSFMEAEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEVAEIEERITKTKLSKEAREKALAELKKLRSMSPMSAEATVVRNYLDWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVGYLAVQARSTKIKGPILCLVGPPGVGKTSLARSIAKATGREYVRMSLGGVRDEAEIRGHRRTYIGSMPGKVIQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSAMLEVLDPEQNATFMDHYLEVEYDLSNVMFVTTANTMNIPGPLLDRMEIIRIAGYTEDEKLEIAKRHLLPKAIKDHALQPKEFSVTEDALRNVIRHYTREAGVRSLEREVMTLARKAVTEILKTKKKSVKITDKNLSDYLGVEKFRFGQIDGEDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGIAMVTAIVSVLTGIPVRKDIAMTGEVTLRGRVLPIGGLKEKLLAALRGGIKKVLIPEENAKDLAEIPDNVKNNLEIVPVSRVGEVLKHTLVRQPEPIEWTEQENPTAVPPVEDEAGASLAH

lon

Lon protease

812 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.

Belongs to the peptidase S16 family.

90.799 kDa

MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISALSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSIDDPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLKHIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFENKRDLKENPDNAKADQDRHPVKNNEEEQTLSLQNYPSVFLFFFFFFFEAIEAFNRFTAAGLKIACPAAILSLN

lon

Lon protease

810 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.383 kDa

MESFAPTRKGRAVFSADAAATAAPGSAGAGETLDPAKDALIIVPVRGFVLFPGIVMPVVLNGPAAIAAAQEAVRQQRSVGILMQRESGAEEASPLNMHRFGVVANILRYITAQDGGHHLICQGEQRFHVEEFLRERPYLAARVKRIEEPDERSPDIEARFVHLQGQASEALQLLPQTPPELIAAVNSAPSPGALTDLVAAYMDASPAQKQDILETIDLRARMDMVAKLLAQRIEVLRLSQEIGRQTKASLDERQREMLLREQMASIQRQLGEGDGKAQEIAELTEAIAKAKMPAEVEEAARKELRRLERMPDASAEYGMIRTYIDWLIELPWSLPEEAPIDIAEARRILDADHFGLDKIKQRIVEYLAVRKLAPQGKAPILCFVGPPGVGKTSLGQSIARAMGRKFVRVSLGGVHDEAEIRGHRRTYVGALPGNIIQAIRKAGARNCVMMLDEIDKMGASAHGDPGSAMLEVLDPEQNSTFRDNYLAVPFDLSRVVFIATANMLDTVPGPLRDRMEIIALTGYTDREKLEIARRYLVRRQLEANGLKPDQVEIDDDALIEIIRGYTREAGVRNLEREIGRVLRHVAVRIADGSASHVHVSRAELTELLGQQRFEDEVAMRLSVPGVATGLAWTPVGGDILFIEATRAPGHGKLTLTGQLGEVMRESVQAALSLIKSRAAELGVDPESFDKTDIHVHVPAGATPKDGPSAGVAMFIALVSILTGRLVRNDTAMTGEISLRGLVLPVGGIKEKVVAAARAGLTRVLLPARNRRDYDEIPQDTREKLEFVWLEKVDDAMAAAFEGMAATPAPN

lon

Lon protease

810 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Involved in iron uptake.

Belongs to the peptidase S16 family.

90.143 kDa

MKEAQSMFEIPRGALYPVPPLRDIVVFPHMIVPLFVGREKSVRALEDVMKDDKQILLVTQKNAAQDDPTPADIYSVGTVGTVLQLLKLPDGTVKVLVEGGQRASITKFAENEDFFQAHADLVEEKVGESQELEALGRAVVSQFEQYIKLNKKIPPEVLVSINQIEEPGKLADTVASHLALKIPEKQQLLECATVSERLERVYAFMEGEIGVLQVEKRIRNRVKRQMEKTQREYYLNEQLKAIQKELGETEDGRDESAELEEKINKTRFSKEARDKALAELKKLRSMSPMSAEATVVRNYLDWMLSIPWKKRTKVKKDLKLAQKILDADHYGLEKVKERILEYLRVQNRMNKVKGPIQSLVGPPGVGKTSLGKSIAKSTGRNFVRMSLGGVRDEAEVRGHRRTYIGSMPGKVIQGMKKAKSSNPLFLLDEIDKLGADWRGDPSSALLEVLDPEQNGTFNDHYLEVDYDLSDVMFVCTANTMRMPQPLLDRMEIIRVAGYTEDEKVEISKRHLIEKQVEANGLKKGEFAISDDALRDLIRYYTREAGVRSLEREIANLCRKAVKEILMKGSAGAKVSVTRRNLDKYAGVRRFHFGEAELEDLVGVTTGLAWTEVGGELLSIEAVSLPGKGRVTTTGKLGDVMKESVQAAESYVKSRATAFGIKPTLFEKRDIHVHVPEGATPKDGPSAGVAMITSIVSVLTGIAVRKDVAMTGEITLRGRVLPIGGLKEKLLAALRGGLKHVLIPKDNEKDLAEIPDNVKRGLEIIPVSTVDDVLKHALVREVEPIEWKEPEAVEPAVAKPQTDGGGEVLRH

lon

Lon protease

810 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

91.333 kDa

MNSEIKSLPLLPLRGILVFPYMVIHLDVGREKSIQAIEEAMVQDRMIFLATQREAQTDEPTVDDIYNIGTVAEVKQLLKLPGGTIRVLVEGIARAKIEKYEHQDPYFRVEVQQYSEEFEKGAEVEALMRSLVYQFEQYVKLSKRIPPETVVSVVNLEEPGRLADIIASHLALKIEDKQNVLESVEIVDRLEKLCGIVAKELEIVELERKINIRVRKQMEKTQKEYYLREQMKAIQKELGEKDERVAECEEFREKISKAKFPKEAEEKALKEVERLEKMPPMAAEAAVVRNYLDWMLSLPWSKSTKDRIDINAAEEVLEADHYGLKDPKERITEYLAIRKLAKKMKGPILCLVGPPGVGKTSLGRSVARALDRKFVRISLGGVRDEAEIRGHRRTYVGAMPGRVIQGMRTAGSKNPVFLLDEIDKMASDFRGDPSSALLEVLDPEQNSTFSDHYIETPFDLSNVMFITTANNMYSIPRPLLDRMEVIQISGYTEEEKLQIAKRHLMPKQIKDHGLTEEMIQISENTILKVIREYTRESGVRNLERKIASICRKTAKKIVAGQAEKVKVTTQNLEQFLGIPRYRYGVAEQNDEVGTVTGMAWTEVGGDTLVIEVTTYKGTGRMTLTGKLGDVMKESAQAGYSFIRSRAQELGIDQEMFEKWDLHIHIPEGAIPKDGPSAGITMATAMASVLTGRKVRHDIAMTGEITLRGRVLPVGGIKEKVMAAHRAGIKLIILPNDNKKDLEDIPVNIKKQLEFKLVDHIDQVLAIALLEKEVVDTTTVLEPEAAVMDNPHFSAVDSQEVQQQGGTQLPS

lon

Lon protease

810 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

92.111 kDa

MPNKNDNKGKYSRLEKEAKKAREEKISIPNVLPAIAMRSNMVIFPNTVVPFYVGREISLMALEEAMEKTNQIVFVVNQKDPAVETPTEKDLYKVGTIVRIIQVGKLPDETFKVLVEGIARAKWIKNVGEKFFKFEIEILRTRYGKSKRLIALMRMVKEELHKYVQYSRKIPPETLMLLEDVDNPDVFADIAASLCPGNIEEKQQLLEIVHPANRLERILDILARETELLEIEQQLDQKVKERIEKSQREYYLREKLRVIRDELGGEEDIEIKELKEKIENNNYPEFVKEKARAEINRLEKMSPYAPEATVVRTYLDWILNLPWHEKTDDTDDINFAEKVLNEDHYGLDEPKRRILEYLATRKVSQKAKAPIICFVGPPGVGKTSLAKSIARAMNRKFGRMSLGGLRDEAEIRGHRRTYVGAMPGRIMQLIRKLGVKNPVILLDEIDKMGISFQGDPASALLEVLDPEQNKEFVDHYIELPYDLSEVLFVTTANVLYTIPPALRDRMEVIEISSYTDVEKFYIAKNYIIPKIESEFVEKADEIFSFKDTAIKKIINEYTLEPGVRELEREIRSVVRKATLDAIKTGKKIVISPEKVTEYLGPSKIKDEDKLEKPMIGVTTGLAWTPNGGTTLYIESTLIPGNGGLIITGQLGDVMKESVRIALSLARKIVGDEYAEKFTKNDIHVHVPEGAVPKDGPSAGVTITTALVSVVKNIPVRNDIAMTGEITLRGRVLPVGGIKEKVMAAYRKGIYHVILPKKNEVDIEKVPEVVRTKMKFTFVETIEEVLEVALNEDNSKESRKGRTRKGNSNTK

lon

Lon protease

809 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.51 kDa

MSEYTRQLPVVALRNMAVMPGMLIHFDVNRKVSIEAIEAAMLLNQQVLLVSQIDAETENPTADDLYRVGTIAEIKQMIKLPGNVIRVLVTGLERATLDSLVSEQPYLKAQLTSKEAELLNLTEAEEEAMVRALRDLFEVYTTENNKLNKDIIRQVEASREIEKMVEQLSIHIPMTLEDKQLLLAASDLMEQYERLCLILADEIEVMRIKRELQNKVKDKVDKNQKDYIMREQLKVIKEELGETSSVSDIMQYLEQLKELVASDEVKEKIKKEIERFQNVAGSNSESAVARGYVETLLSLPWDKVSEDFMDLAYAKEVLETEHYGLKKVKERVLDFLAVRQLTEKGDSPIICLVGPPGTGKTSIARSIAKALNKEYVRISLGGVRDEAEIRGHRRTYVGALPGRIITGLKQAKVKNPLMLLDEIDKMSSDYKGDTASAMLEVLDSEQNCNFVDHYVEIPVDLSEVMFIATANTTQTIPKPLLDRMEIIEVSSYTENEKFHIAKNHLLNKQIEKNGLKKSQISISEKALRKIISDYTREAGVRGLERKISEVCRKIARELLEQESKENQNLIKSAKNKSNNKNQSHSEVAAAVEAEEISVTTKPSKIKVTEKNITTYLGKPKFRNEIASQKDEVGIVCGLAWTSVGGTTLQIEVNSLPGKGALILTGQMGDVMKESAQLGISYIRSLSKEYKISEEYFQKNDIHIHIPEGATPKDGPSAGITMATAMLSAITGKKVHAKVAMTGEITLRGRVLPIGGLKEKLLAAKNTGIKKVLIPEKNRPDLEELEQEITEGMEVICVATMDEVLKHALV

lon

Lon protease

809 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.847 kDa

MSEQRSDEPEVVDAIIEDQQGAQATTDATPPVRIENSLPTELVIYPLGGRPFFPGMLTPIQVEGSPYYETIKKAMDSHGRLFGILASHAEDGQEVFDANQLFGIGTVVRILEASVNEEAKQIKLLAEGLWRFEVRDVVSVGPPIVAQVTHHNNPVSVVDTDALKPYTMAVINTLKEILKYDSLYQEQVKMFLSRHNFSEPDRLADFVASMTSSSREELQEVLETLPIMARLEKVLTLLKKELEVVKLQNKIQRQVEEGIAEHQRQFFLREQLKEIQKELGITKDDRTAEIDRFRERLEKLTLSEEAEQKIEEELDKLAILETGSSEYGVTRNYVDWLTSLPWGVHSTDKLNIARARRILDRDHDGLEDVKERILEFLAVGKLKGEIGGSIILLVGPPGVGKTSIGRSVATAVGREFYRFSVGGMRDEAEIKGHRRTYVGAMPGKFVQAIKHTKVANPLIMLDEVDKIGASYQGDPASALLEVLDPEQNSEFLDHYMDVRFDLSKVLFICTANQLDTIPRPLLDRMEVIRLSGYITSEKVRIARNHLLPKQLEKNGLDKSQLRVSNGALREIIEGYAREAGVRRLEQKIGAIARKVAVKVLEEAELPISVGQNDLDSYLGKPDFREEKPLTGVGIVTGLAWTALGGATLDIESAQTSTEGNTLLLTGQLGDVMKESARIAFSFLQSNVEKLGGKSERLKGNIHLHVPEGATPKDGPSAGITIATALLSLARTQPLPRRLAMTGEITLTGSVLAVGGVREKVIAARRVGIRELIIPEACRKDYDEVPEHIREGFTVHFVKKYAEVAKLVFG

lon

Lon protease

809 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.128 kDa

MSELIMNEKTDLEPQVPSVLPLLALRDVVVYPHMQIALFVGREKSINAVDVARNSDNLVFVVAQKDSLTEEIDHDNLYQYGTVAKIVQVVNHENDENCIKVLIEGLHRSKLKKIIDEDSYLTAEHELSPMTINVDKATQETRLQELRNLFAQYAEAKLRNARELVAAANKIEDLLQLMFFVATRVPLNIEIKQKFLEYDEFEAHLQELMNYLMNQSAEQQIEQTLHDSVKRQMEKNQREYFLNEKMKVIQRELSDMNGGAEDDVAEIEKRLAEADLPEHVRKKAEAEFRKLKAMQPASSEAAVVRNYLEVILDTPWNKASKVSINLNKAQEILDADHYGLDDVKDRIVEYLAVQSRVKKLKGPILCLVGPPGVGKTSLGESVAKATGREFVRMALGGVRDEAEIRGHRRTYIGAMPGKIVQSLTKVGVKNPLFLLDEIDKMAQDYRGDPASALLEVLDPSQNSKFNDHYLDLDLDLSEVMFICTANSMNIPEALLDRMEVIRLPGYTEDEKVNIAERYLVPKAIKNNGLRPKELTIHEEAIRDIVQRYTREAGVRNLEREVSKIARKVVKEAVSKKSKNLQLDVTSANLPEYLGPHKFDFGMAEDEAQVGRVNGLAWTSVGGELLTIEVAAVKGKGKFITTGSLGDVMKESITTAMTVVRTRADELGIEASRFEETDVHVHLPEGATPKDGPSAGLALTTALVSAFTGIAIRPDIAMTGETSLGGRAMRIGGLKEKLLAAHRGGIKLVFIPQDNVRDLAEIPDNVKEGLEIKAVKSIDEILPLALTSMPKPLPKTPIVKPVEGSKAARH

lon

Lon protease

806 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). In R.meliloti it is important for controlling the turnover of a constitutively expressed protein(s) that, when unregulated, disrupts normal nodule formation and normal growth.

Belongs to the peptidase S16 family.

89.458 kDa

MTNKTSPATESATYPVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGTDKQIMLVTQINATDDDPEPSAIYKVGTIANVLQLLKLPDGTVKVLVEGRSRAEIERYTPRDDFYEAMAHALPEPDEDPVEIEALSRSVVSEFESYVKLNKKISPEVVGVASQIEDYSKLADTVASHLSIKIVEKQEMLETTSVKMRLEKALGFMEGEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEMAELEERISKTKLSKEAREKADAELKKLRQMSPMSAEATVVRNYLDWLLGLPWGKKSKIKTDLNHAEKVLDTDHFGLDKVKERIVEYLAVQARSSKIKGPILCLVGPPGVGKTSLAKSIAKATGREYIRMALGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSALLEVLDPEQNSTFMDHYLEVEYDLSNVMFITTANTLNIPPPLMDRMEVIRIAGYTEDEKREIAKRHLLPKAIRDHALQPNEFSVTDGALMAVIQNYTREAGVRNFERELMKLARKAVTEILKGKTKKVEVTAENIHDYLGVPRFRHGEAERDDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGVAMATAIVSVMTGIPISKDVAMTGEITLRGRVLPIGGLKEKLLAALRGGIKKVLIPEENAKDLADIPDNVKNSLEIIPVSRMGEVIAHALLRLPEPIEWDPASQPAALPSVDSQDEAGTSIAH

lon

Lon protease

806 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.835 kDa

MLTSKEKSDTKRLPMMPIRDVVIFPYMMTPFVVGRESSVRALEEAMAGDKKIFLATQHDASIDEPKPNEIYSVGTIVNIVQSLKLPDGNIKVLVEGVERAKVVSVADDEGFFRATVRTSGFKVETGPQLDALISRVTTLFEQYVKLSQNLNYETMVAAIRVDEPGKLADTVGANLQLTIEEKQELLEIFDPIDRLTRVAEMLDIEIEKLNVDRTIQGRVKRQMEKAQKEYYLNEKIKAIQKELGRGEKSEIDELKRRIEEAGMTADAQEKAMAELKRLENMPPMSAESTVSRNYLDWLLAVPWKKKSKEIRDLKFAEGVLEADHYGLEKIKERILEFLAVRRLVKNPKGSILCFVGPPGVGKTSLGMSIAKATGRKFVRMSLGGVRDEAEVRGHRRTYIGALPGQIIQMMKKAGTRNPVFMLDEVDKMSMDFRGDPSAALLEVLDPEQNFMFVDHYLDVEYDLSQVFFVATANVMHTIPAALQDRMEVIRLSGYTELEKMEIAKRFLVKKQIEATGLDSKQIDFQDDGINSLIQYYTREAGVRNLEREIGNVCRKVARQVVNAESGKDKKAPAKAVINGDKVPELLGPWKFRDLVVEKKNEIGAATGLAWTEVGGQLLTVECTLMEGKGKLTITGKLGEVMQESAQAAMSYIRSRAMSLGIPRDFYRNLDLHIHIPEGAIPKDGPSAGITLATTICSALTKIPVRGDLAMTGEITLRGKVLPIGGLKEKLMAAHRHGILEAIMPKENEKDLPDIPDAIKKTMKLHFVESMDEVLKIALEREIVALPIPGAELPVEAGKPAEETVAH

lon

Lon protease

805 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.595 kDa

MQINENKGFPTEIPIIVEDELFLYPFMITPLFLSDEENLKALELAIQGETPILVVPTKPQQDGARDFDGIYDAGVIGTIMRRVPLPDGRVKVLFQGIDKGKILKQSGINPLRGIVDMLHVKRPSQVKTDALIVVLREKVRELSQFNHFFPPDLLKTIEESAEAVRVCDLVSSALRLKKQIAYSFFVEENLEQRLLKLIDYVIEEIEANKLQKEIKNKVHSKIDKTNKEYFLKEQLKQIQAELGADTSREEELEEYRKKLDAKKKFMAEDAYKEIKKQIDKLSRMHPDSADANTLQSYLDWVLEIPFENVAKKKSSIAEVSKHLNADHYSLEKPKERIEEYFALRELLELRGVGEKVNNGAILCFAGPPGVGKTSLANSIAKALKRELVRIALGGLEDVNELRGHRRTYIGAMPGRIVQGLIEAKQMNPVVVLDEIDKVGRSYRGDPTAVLLEILDPEQNNKFRDYYLNFNIDLSKIIFIATANDVSMIPAALRDRMEFIELSSYTPQEKFEIAKKYLLPQELKKHGLKPSDVSISKEALELIISDYTRESGVRNLRRRIADILRKVAKNILTKKNEGKISVTAKNLKEFLEKKVYEIEPADKKDQIGLVNGLAWTSVGGDVLRIEAIRIQGKGSMQITGQLGDVMKESAQIAFSVVKVLIDNKKLKVPMPIVPKFDDDKHKLEASDVYRRYDLHLHVPEGAVPKDGPSAGITMATAIASILTDTKVKHDIAMTGEITLTGRVLPIGGLKEKLIAAHKAGIKTALIPRKNYDRDLVDIPAEVKADMKIIAVDTIDDVLKNALVAKK

lon

Lon protease

805 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.595 kDa

MQINENKGFPTEIPIIVEDELFLYPFMITPLFLSDEENLKALELAIQGETPILVVPTKPQQDGARDFDGIYDAGVIGTIMRRVPLPDGRVKVLFQGIDKGKILKQSGINPLRGIVDMLHVKRPSQVKTDALIVVLREKVRELSQFNHFFPPDLLKTIEESAEAVRVCDLVSSALRLKKQIAYSFFVEENLEQRLLKLIDYVIEEIEANKLQKEIKNKVHSKIDKTNKEYFLKEQLKQIQAELGADTSREEELEEYRKKLDAKKKFMAEDAYKEIKKQIDKLSRMHPDSADANTLQSYLDWVLEIPFENVAKKKSSIAEVSKHLNADHYSLEKPKERIEEYFALRELLELRGVGEKVNNGAILCFAGPPGVGKTSLANSIAKALKRELVRIALGGLEDVNELRGHRRTYIGAMPGRIVQGLIEAKQMNPVVVLDEIDKVGRSYRGDPTAVLLEILDPEQNNKFRDYYLNFNIDLSKIIFIATANDVSMIPAALRDRMEFIELSSYTPQEKFEIAKKYLLPQELKKHGLKPSDVSISKEALELIISDYTRESGVRNLRRRIADILRKVAKNILTKKNEGKISVTAKNLKEFLEKKVYEIEPADKKDQIGLVNGLAWTSVGGDVLRIEAIRIQGKGSMQITGQLGDVMKESAQIAFSVVKVLIDNKKLKVPMPIVPKFDDDKHKLEASDVYRRYDLHLHVPEGAVPKDGPSAGITMATAIASILTDTKVKHDIAMTGEITLTGRVLPIGGLKEKLIAAHKAGIKTALIPRKNYDRDLVDIPAEVKADMKIIAVDTIDDVLKNALVAKK

lon

Lon protease

805 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.289 kDa

MTDKIYPILPLRDVVVFPHVIVPLFIGREKSIAALDAAMNGSQELLLVPQRDPAVVEPTLADLHEIGSLGRIVQMAKLSDGTVKALVEGLYRVHLEALNDDEKMFSAKKRNMLEKNSTKSEEHDSIVEILIEEFAKYLRNQERSADELLETLRGINDIGRISDTIAAHMDFRIEERVHLLAMEDAYERSQRLMILLAQESEKNELNKKIKNRVKQQMERNQREYYLNEKIKAIQKELGEMDEAQNDIELLEAQIKKAKMPVDVEKKALSELNKLKQMSAMSSEANVIRNYLEWLIDYPWAIEKPARYDLEEAARILDRDHYGLEDVKERILEYLAVQKRINEHNQKEAGTIGKGPIICLIGPPGVGKTSLGKSIAEATGRDFDRIALGGLHDEAEIRGHRRTYIGALPGKIVQKLCKLGSNNPVILLDEIDKIGHDHHGDPAAALLEVLDPAQNHTFNDHYLETDIDLSNVLFIATANTLNISEPLLDRMEVIRLPGYTTQEKIQIAKRYIVPRQRKENVLKASEFKIKNGVLNDVIEDYTREAGVRNLEREIGKLARKSVRRLQEGKQKSILITPNNLKDFLGVAKYHRNDEDLQAKIGSVTGLAWTSVGGELLQIEGVAFSGKGRLTHTGQLGDVMQESIRTALSVVRSYLDDLDDNFRFDEYDIHLHLPEGATPKDGPSAGIAMATALLSALSKQAVRGDLAMTGEITLHGKVLAIGGLKEKLLAAQRGRLKMVLIPEDNLKDLDEIPEEVKAALEIVPVSHIHEVFDHAFVADHAPFKARIEQKSLPTVSAVMHETPAGRC

lon

Lon protease

804 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.789 kDa

MSADSENETSESSPAGEATASTSALPDEPLILLPVRNAVLFPGMVLPFTAGRGQVKEDVQAAVKRQQPLGVVLQRDPRVQDPTFDDLNTIGTVANVVRYVTSPEDGAHHLICQGVERFRLIAPVEGLGFRAARVEFLPETTARNPAVDARALVLRQRAGEMIGLLPNAGGELVRALDAIELPGLLADTIAGLLDIPPERKQEILETLDVCKRLDKVLDAVAGRIEVLRLSQEIGEQTRGRIDQRQREMMLREQLRTIQNELGENIESREEVRKLTEAIEAAHMPPEVESHARKELGRLERMPEASSEYSISVSYLEWLTELPWPLPAEAPIDIARARQILDEAHFGLDKVKRRILEYLGVRKLNPHGKAPILCFLGPPGVGKTSLGQSIARALERPFVRVSLGGVHDEAEIRGHRRTYIGAMPGNIIQAIRKAGARNCVMLLDELDKLGQGVHGDPAAAMLEVLDPEQNASFRDNYLGVPFDLSAIVFVATANQIEGIAGPLRDRMEILDLPGYTEAEKFQIAQRFLVPRQLEACGLTAAQCELPDETLRAIIRDYTREAGVRSLERQIGAVFRYVALRVAEDPSTHERIEPDRLSSILGHRRFESEVAMRTSLPGVVTGLAWTPVGGDLLFIEASSTPGGGRLVLTGQLGDVMKESVQAALTLVKSRCESLHIDCSNFDKRDIHVHVPAGAVPKDGPSAGVAMFIAIASLLMGRAVRSDCAVTGEISLRGIVLPVGGIKEKVLAALRGGIKTVLLPARNAPDLEDIPVDARNQMRFVLLETVDDAVREIIEDESVTSSRNVDI

lon

Lon protease

803 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.347 kDa

MAKNTQRTMPVLPLRDVVVFPYMVMPLFVGRAKSINALEEAMNDDKQILLVSQREADLEEPTPEDLFDVGTIANIIQLLKLPDDTVKVLVEGQNRAKINSLEDGEKCFSAQITPIETTYGDEKELVVAKSAVLSEFENYLTLNKKVPTDILNALQRIDDVDRLADTMAAHLPVSIRHKQNALELANVQERLEYLLGMMESEADILQVEKRIRGRVKKQMEKSQRNYYLNEQIKAIRKEMDGGENEDTIDEVEQLHQKVEAAGMPADVRDKVENELQKLKMMSAMSSEATVIRSYIEWMIQVPWHQRSKVKKDIVKAQQVLDTDHYGLDRVKERILEYLAVQARLNKVKGPILCLVGPPGVGKTSLGQSIANATGRKYVRMALGGVRDEAEIRGHRKTYIGALPGKLIQKMAKVGVKNPLFLLDEIDKMASDMRGDPASALLEVLDPEQNTTFNDHYLEVDYDLSDVMFVATSNSMNIPGPLLDRMEVIRLSGYTEDEKLNIAMRHLLAKQIERNGLKKGELTVEESAILDIIRYYTREAGVRGLEREISKICRKAVKNLLVNPKLKSITVNSDNLHDYLGVKRFEFGKADTQNRIGEVTGLAWTEVGGDLLTIETASVVGKGKLSFTGSLGDVMKESIQAAMTVVRARADKLGINAEFHEKRDIHIHVPDGATPKDGPSAGIAMCTALISCLTGNPVRADVAMTGEISLRGKVLPIGGLKEKLLAAHRGGIKTVLIPKENVKDLEEIPENVKQNLAIHAVETIDEVLGFALENPPEGIEFVKVEAKPKAPRRKVTSKSERAVN

lon

Lon protease

802 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.744 kDa

MRRLTMYPEQPDENRESIVMPLFEVVVYPKSRAKFLADKVTGEILLNDMKNAESVSAIGLTVKNGTKASDLSEESLYKIGNLLNITYVQPSDDGYLVVAKGIERVEAVSLYQKNGLFYATYRPVHDLPDFDEDAETEVMANIKKTIHEISARFQGSEQFTKSIDKMDSIDQIMGFVMPYIPVKLAEKQRLLELASVRERYLLFLHILTKHKENINLQIEMAKKVTDKISKSNREAMLREQLKVIQEELNEGDDSASGDAAYREKIENSTMPDEVKKKAFSELKKLETGGSHNPEAPGIRNYLDLLLDLPWITEEKKSIDIAEARRVLESNHNGLEKVKERIIQHLAVMKLKHEKQGSILLLIGPPGTGKTSLGKSIADALGRKYIRISLGGVKDEAEIRGHRRTYIGALPGRIIQGMRKAGTKNPVFILDEVDKLSASYSGDPASALLEVLDPEQNSTFSDHYLEIPYDLSDVLFIATANSMANIPWPLLDRMETIEISGYTKNEKLAIAKDHLVPCILEDHGLDAEKLKIEDEALKVIIDKYTREAGVRGLKKQLAKTARFVSEKIVSGKADLPYVVRADMLKEILGKEIIRQEEARKENVPGVVTGLAWTPVGGDILFIEGTFMPGSGKLTLTGQLGDVMKESAKISLSLVRSRLANTANSFDFTSSDIHIHVPSGATPKDGPSAGVTLFTALTSLIIGKAVDPKLAMTGEITLSGAVLPVGGIKEKVLAAHRAGIKKIILPKENERDLEDVPEDARNELQFVPVETIEEVLREALDIDLPRPVVPSSYPGSSYAPAHSV

lon

Lon protease

802 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.373 kDa

MSELDRFSNDKNEMPKIPDVLPLLPVRDIILYPAMVLPLAVGREKSIKALEESMSTNRLVFIVTQKNIQIEDPTPKDVYNIGTICEVLQMLKMPDGTLKALVEGISRAQWTDFKLSDKGYIEVGLKVFDENTLKMPEVEAIMRQTIALFEQYVKLNPRIPIDISVSVSNIADPARLADTIASHLVIKNNDKQTILELVDPVKRLEKIIQILNAEIEILNIERRIQNRVRNQIEKTQKEYYLTEQMKAIQKELKQKDEAQKDLDDLKGKLKKTKMPQAAKSAADKEMSRLEKMMPMSPEATVIRTYLEWILDLPWEKSTIDNLDLNRAKEVLDQDHYGLEKVKDRVLEYLAVLSRVQKIKGPILCFIGPPGVGKTSIAKSVARSLGRNFVRISMGGVKDEAEIRGHRRTYIGSMPGKIIQSIKKAGSNNPVFILDEIDKIGSDWRGDPSSALLEVLDPEQNYTFNDHYLDVDFDLSNVMFITTANTLNNIPVTLFDRLELIRFSSYTDVEKRHIAEDFIVPKQLKEHGLKPEEFIFDDGALDIVIKNYTHEAGVRNLTREIANLCRKVVKGLEFNKELKSITIKPENLNKYLGIAYYERERIAENDVGVATGLAWTEVGGETLTIEVNKMGGKNSLVLTGKLGDVMKESAQAALTYVRSSSQKLKIDENMFSNTDFHVHVPEGAVPKDGPSAGIALATALASVCMNKPIKKKIAMTGEVTLRGRVLSIGGLKEKVLAAYREGITMILFPESNKKDLVDIPEDVIKKLQMIPVSHMDEVISLTIERLPENKNIKMDKRNGENGI

lon

Lon protease

802 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.113 kDa

MSTPLPTQDPPDIPEVLPILPLNNVVLFPGMFLPLVVSGDTWVKLVDEAALATKMVGVFMRTQPGEGFDPLALARTGAVALIVRMLRLPHGAVQILVQGQARIQIRQLIVTEPYPQARVAIHRDPAVLSVEVSGLARAALAAFQQIIQLSPTLPDELAIVAANTAQPGMLADLIAANLNLKPEDQQLVLDTLDVQERLRQVLSFLEREREILTIGRKAQEEMSKSQREYVLRQQLEAIKRELGETDDHAAEIAELRRRLEAANLPEEARKEAEREISRLERMPPGAAEYVVARTYLDWLLDLPWNVSTEDNLDLTQARQVLDEDHYDLERIKERIIEYLAVRKLRLEQDASGSARGPILCFVGPPGVGKTSLGTSIARALGRKFVRVALGGVRDEAEIRGHRRTYIGALPGRIIQGINRAGSNNPVFMLDEVDKLSVGFQGDPAAALLEVLDPEQNVAFVDRYLDVPFDLSRALFICTANRSDTIPPALLDRMELLELAGYTEMEKLEICRRYLIQRQRNEQGLAERAPTITEAALRRLIREYTHEAGVRDLERRIGAIYRKMATRAAEGQPLPDQVDAPDLDDLLGPPRFRSETLLGEDEVGVVTGLAWTPTGGDVLFVEASVVPGNGQLTLTGQLGDVMKESARAALTYARSRARALNIPTDFAQICDIHIHVPAGAVPKDGPSAGITMASALISALTDRRAYKHVAMTGEITLRGKVLPIGGVKEKVLAAQRAGVRTVLLPKANAPDLRELPEETRQQIDIVLVEHMDEVLPRVLHPKSESVTLAEPAPPDGAGTVQAT

lon

Lon protease

800 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.763 kDa

MGPFEDKLDLLELPSTYPLIPTRDVIVFPYMVFPLFIGRPFSIKAVEEALDNNQRYIFLSLQKDKEKEIPTKKDIHEIGVVATIIRMMKLEDNRIKILVQGVSRGRIKELKKVDDYYQVGVEIIEDPEVEETLEVQALKHSLKDLLDKAISLGKQIVPDLVEIIKSVEEPGRLADLVASILDIKAEEAQQILEILDPVERLRVVHDKFLKEVGILELQQKIRISAREAIEKDQREYFLRQQIKAIQEELGERDEKQEEIENYKKKIEESGMPDEIKEEALKQLKRLEKMHPDSAEAGVIRTYLDWLVELPWNKRTKDRLDLKIAKKILDEDHYDLEKIKERILEYLAVLKLKKESSKDKSIKGPILCFVGPPGVGKTSLGRSIAKALNRKFVRISLGGVRDEAEIRGHRRTYVGAMPGKIIQAIKQARTKNPVIMLDEVDKIGLDFRGDPTAALLEVLDPEQNKEFIDHYLGVPFDLSEVMFICTANRLDTIPRPLLDRMEVIRLSGYSEEEKLHIAKKYLIPKQLKENGLDEKTVEFSDKAITFLIRGYTREAGVRNLERQIGSIIRKIAKKIIETGKKRKYKITPSLIKKFLGAPIYSTEKEEKDEVGVVTGLAWTEVGGEILKIEVTKMDGKGNLVLTGSLGDVMKESARIAFSYVKSKAKELGIDPEEFGKYDLHIHVPAGAIPKDGPSAGIAITTGIASVFTNRPVRSDVAMTGEITLRGKVLPVGGLKEKILAAKRAGIKTVILPKDNKEEVMSDLPPYVRKSMNLIFVDHIDEVFKIALREEKKEVENQESES

lon

Lon protease

799 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). CcrM is an important target of the Lon protease pathway in C.crescentus (By similarity).

Belongs to the peptidase S16 family.

88.244 kDa

MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH

lon

Lon protease

799 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). CcrM is an important target of the Lon protease pathway in C.crescentus.

Belongs to the peptidase S16 family.

88.244 kDa

MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH

lon

Lon protease

799 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). CcrM is an important target of the Lon protease pathway in C.crescentus (By similarity).

Belongs to the peptidase S16 family.

88.244 kDa

MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH

lon

Lon protease

799 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). CcrM is an important target of the Lon protease pathway in C.crescentus.

Belongs to the peptidase S16 family.

88.244 kDa

MSELRTLPVLPLRDIVVFPHMVVPLFVGRDKSVRALEEVMRGDKQILLVTQKNSADDDPAPGDIFEVGVLATVLQLLKLPDGTVKVLVEGKARAAVVSFTDQESYYEAQIGEVSEDDGAGPEAEALSRAVVEQFENYVKLNKKVPPEALASIPQIAEPGKLADSIAAHLSVKIGDKQNLLEIFDVVKRLEKVFALMEGEISVLQVEKKIRSRVKRQMEKTQREYYLNEQMKAIQRELGDPDDARDELIDLEKRIKKTKLSKEARTKAESELKKLRNMSPMSAESTVVRNYLDWLLSIPWGKAKTKKIDLVESEGILDADHYGLEKVKERILEYLAVQARTNSLKGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKVVQSMKKAKTTNAFVLLDEIDKMGSDYRGDPASALLEVLDPSQNSTFGDHYLEVDYDLSQVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKLEIAKRHILPKLAKDHGLKPAEFIVPDKAIRDLIRYYTREAGVRSLERELGALARKTVRDLAREKVASITIDDERLAKYAGVKKYRYGETDEVDQVGIVTGLAWTEFGGDILTIEAVKMPGKGRMQITGNLKDVMKESIAAANSYVRSRALQFGIKPPVFEKTDVHIHVPDGATPKDGPSAGIAMALAMVSVLTGIPIRKDIAMTGEITLRGRVTAIGGLKEKLLAALRSGVKTVLIPQENEKDLADVPQTVKDGLEIIPVSTVDEVLKHALTGPLTPVEWNEAEEPITTSAKKDDGDSDAMLTH

lon

Lon protease

796 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.443 kDa

MLQYLKKIKGVSFMKTIKLPVVVTRGIFILPSTSKTIEFGRVKSKNALDASADLYNNQIVVVSQESPLEEEPNLEHLFYLGTVADLSVKKVWKDGTISVELNYNQKIKIDEFVEEDNIIYAIGSVFEDKLPKTDAQKTKIKEALEELQEKHSFNTSELLLVFNENDFNKLNSLIYQIIDKMPLVSLNTKLLLIQSTSILEKLELLKELIINRPKSTIKLNNNLNNNSTVDSEINKKLKDKMDKQQKEYYLREKMRIIKEELDDENSDASQLDKYKKRLEEEPFPESVKEKILSSIKRIETMQPGSAEVNVERNYVDWMMSIPWWEQSEDIDDLKYAQEILEKHHFGLKKVKERIIEYLAVKQKTKSLKGPIITFVGPPGVGKTSLARSIAEALGKKFVKVSLGGVKDESEIRGHRKTYVGSMPGRIIQALKRAKVKNPLFLLDEIDKMASDNRGDPASAMLEVLDPEQNKEFSDHYIEEPYDLSTVMFIATANYIENIPEALYDRMEIINLSSYTEIEKMHIAKDYLTKKILEEDQLTEDELRFTDEAYDEIIKYYTREAGVRQLERHLATIARKFIVKLLNGEITNLVVTREVVVQYLGKHIFEHTSKEEESQVGVVTGLAYTQFGGDILPIEVSTYNGKGNLTLTGKLGEVMKESATIALTYVKANHEKFGISKDKFDDIDIHIHVPEGAVPKDGPSAGITLTTALISALSKQPVSKDFGMTGEITLRGNVLPIGGLREKSISAARSGLKHILIPSKNVKDIEDVPQEVQDVLKITPVSKYEDVYEIIFKNNNQ

lon

Lon protease

795 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.166 kDa

MINLDDKNNIGRVIPVSDIVLLPGMYHTLKFNKFSETQIESLSDEDIVNIALPLKQNFGQSKLKEEDFHRVGVTFQVNAIEKTEKGYKAEIKILDRVEIKTFSIEEDSIKAEFEFAPDIIDLTEKSKDEMVEYIKKVTREISENFKGSEKFMLAVEGQKDLNKLMGYLSHFMQISSEEKYDLLETQSLKDRGLKFIDYLLKQKESLKLQFELAEKFTEKANKNYRETVLREQLKAIQEELNEGKSSPSKKDKNYLNRIEEAQMPDEIKEVALEELGKLESQSPNSAEYNVIKNYLELLIQLPWKKQEFKDIDLEEARRILDEQHYGLEKVKDRIIQHLAVMQLKNDKKGSILLLVGPPGVGKTSLGKSIAEALNRKYVRLSLGGVRDEAEIRGHRRTYVGAMPGRIIQSIKKAGEINPVMVLDEVDKLMASYNGDPASALLEVLDPEQNDTFTDHYLDVPYDLSNVFFIATANSLDTIPRPLLDRMEVIQISSYTMNEKFHIGKNHLISAVLEEHGLNDTQLVIEDAALERIISEYTLEAGVRGLKKQIATIARIASEKIVSNKVELPFKVKEDDLEDLLGRKVSSHDKAQDDNVPGVVTGLAWTSVGGEILFIEATGMLGSGQIVLTGQLGDVMKESAQISLSLLKSRLPINAINFRERDIHIHVPSGSVPKDGPSAGIALFTALASLVTGIKVDSKLAMTGEITLRGAVLPIGGLKEKLLGAQRAGITKVLIPKDNVVDLNEVPQEVKEQLTIIAVETVEDVLRETLGISLPRIEHIFNPNKFIEGTFKPAEE

lon

Lon protease

795 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.166 kDa

MINLDDKNNIGRVIPVSDIVLLPGMYHTLKFNKFSETQIESLSDEDIVNIALPLKQNFGQSKLKEEDFHRVGVTFQVNAIEKTEKGYKAEIKILDRVEIKTFSIEEDSIKAEFEFAPDIIDLTEKSKDEMVEYIKKVTREISENFKGSEKFMLAVEGQKDLNKLMGYLSHFMQISSEEKYDLLETQSLKDRGLKFIDYLLKQKESLKLQFELAEKFTEKANKNYRETVLREQLKAIQEELNEGKSSPSKKDKNYLNRIEEAQMPDEIKEVALEELGKLESQSPNSAEYNVIKNYLELLIQLPWKKQEFKDIDLEEARRILDEQHYGLEKVKDRIIQHLAVMQLKNDKKGSILLLVGPPGVGKTSLGKSIAEALNRKYVRLSLGGVRDEAEIRGHRRTYVGAMPGRIIQSIKKAGEINPVMVLDEVDKLMASYNGDPASALLEVLDPEQNDTFTDHYLDVPYDLSNVFFIATANSLDTIPRPLLDRMEVIQISSYTMNEKFHIGKNHLISAVLEEHGLNDTQLVIEDAALERIISEYTLEAGVRGLKKQIATIARIASEKIVSNKVELPFKVKEDDLEDLLGRKVSSHDKAQDDNVPGVVTGLAWTSVGGEILFIEATGMLGSGQIVLTGQLGDVMKESAQISLSLLKSRLPINAINFRERDIHIHVPSGSVPKDGPSAGIALFTALASLVTGIKVDSKLAMTGEITLRGAVLPIGGLKEKLLGAQRAGITKVLIPKDNVVDLNEVPQEVKEQLTIIAVETVEDVLRETLGISLPRIEHIFNPNKFIEGTFKPAEE

lon

Lon protease

795 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.988 kDa

MPVTKKSQILVVRGQVIFPFVPFSLDVGRPRSRKIIKALKTLKTKRLVLVTQKFTGEQNPEFNDIYHVGTLCEIDEIVDVPGVDSKTVDYRIKGRGLQRVLIEKFSDADINEVSYQLLNSTVKDEANVDRFLQRIFPEKEEIEQLMEGAEKFLELENISKTVNVPKGLKQLDIITFKLANLVPNTESIKQAILEENEIANRLEKIIQAGIEDLQKIQDYGRSKNKETEFDKLDSKITRKINEQLSRQQRDFYLREKLRIIREEIGISSKKEDEVASIRKKLDENPYPEAIKKRILSELEHYENSSSSSQESTLTKTYIDTLLNLPWWQKSKDNSDVKNLIKTLDKNHTGLDKVKERIVEYLAVQLRTQKNKGPIMCLVGPPGVGKSSLAKSIAEALDKKFVKISLGGVHDESEIRGHRKTYLGSMPGRILKGMTRAKVINPLFLLDEIDKMTSSNQGYPSGALLEVLDPELNNKFSDNYVEEDYDLSKVMFIATANYIEDIPEALLDRMEIIELTSYTEQEKIEIAKNHLIKRCLEDADLNSEELKFTDEAISYIIKFYTREAGVRQLERLIQQVVRKYIVAMQKDGIKQETIDVNAVKKYLKKEIFDHTMRDEVSLPGIVNGMAYTPTGGDLLPIEVTHVAGKGELILTGNLKQTMRESANVALGYVKANAERFNINPSLFKKIDINIHVPGGGIPKDGPSAGAALVTAIISSLTGKKVDPTVAMTGEITLRGKVLVIGGVKEKTISAYRGGVTTIFMPEKNERYLDEVPKEIVDKLNIIFVKEYSDIYNKLFS

lon

Lon protease

795 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.204 kDa

MPAVKKPQILVVRNQVIFPYNGFELDVGRERSKKLIKALKNLKTKRLVLVTQKNSDQLNPEFDDIYHCGTLCDIDEIIEVPSEDGKTADYKIKGKGLQRVAITSFSDADLTKYDHHFLNSTLTENKALDKLLERIFPDKEDFAEILDSLNSFLELQELKKLSKVPKDIKRYDIITFKLASLIFKDITLQQAILEENDIEKRLQKIIGSGIEDLGHISEEARAKQRESEFDKIDNRITRKVNEQLSRQQRDFYLREKLRVIREEIGMTSKKEDEVSNIRKKLEENPYPEHIKKRILSELDHFENSSSSSQESTLTKTYIDTLMNLPWWQESKDNADVKNLIKILNKNHSGLDKVKERVVEYLAVQLRTKKLKGPIMCLVGPPGVGKSSLAKSIAEALNKCFVKVSLGGVHDESEIRGHRKTYLGSMPGRILKGMVRAKVINPLFLLDEIDKMTSSNQGYPSGALLEVLDPELNNKFSDNYVEEDYDLSKVMFVATANYIEDIPEALLDRMEVIELTSYTEQEKLQITKSHLVKRCLDDAEIKTDDLKFTDEGISYIIKFYTREAGVRQLERLIQQIVRKYIVNLQKTGEQQVVVDVDLVKKYLKKEIFDYTVRDEDALPGIVNGMAYTPTGGDLLPIEVTHVAGKGDLILTGNLKQTMRESASVALGYVKANAQSFNINPNLFKKVDINIHVPGGGIPKDGPSAGAALVTAIISSLTGKKVDPKIAMTGEITLRGKVMTIGGVKEKTISAYRGGVRTIFMPEKNERYLDEVPKDIVKDLEIILVKEYKDIYNKIFN

lon

Lon protease

795 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.972 kDa

MNELFQTPQVEAGIKEYPLMPLRDIVIFPTMVQPLFVGRRFSIRAIEEANKKDKLIFLVLQKDKDVEEPKEEDIYKVGVVAYILRTVPIEDARVKVLVQGLKRGVIKKLEWKEDHYVAQVDVIEERDIPPESQTIEDKALIKAVKESIDKLVSLGKQIIPDLVVLIKELEEPGKLADMVASILDIKSSQAQEILETFDPRERLKKVYKFLQDEIGLLEVKQRISEIARERMEKEQREYYLRQQLKAIQEELGEAGGIKAEIEEYTKKFEEVKECMPEEGVKEVEKNIKRLERLHPESAEAGVIRTWLDWVLDLPWCTRTEDNYDLERAREILDRDHYDLEKVKDRIIEYLAIRKLTQGKEAPTQILAFVGPPGVGKTSLGRSIAEALGRKFVRIALGGIRDEAEIRGHRRTYVGAMPGRIIQAIKQAGTKNPVIMLDEIDKLAISFQGDPAAALLEVLDPEQNKKFTDLYIGIPFDLSEVIFICTGNRADTIPTPLLDRMELIMLSGYSEEEKLFIAKKHLIPKLIPLHGFSPEEIEFTDEAILEIIRGYTREAGVRNLQRQISAVLRKIAVKKLQGEKGPFNITPELVRKLLGVPRYRPEREKKPLVGVATGLAWTEVGGEIMFIEATKMKGKGSLVLTGSLGDIMKESAQAALSYIRSKAEDYGIDPDIFSQVDVHVHVPEGAVPKDGPSAGVAIATALLSLFTDIPVRMDVAMTGEITLRGRVLPVGGLKEKILAAKRAEIYEVILPAKNKDEVMEELPEYVREKMTLHFVDNLEEVFKIALVREPKPLKEA

lon

Lon protease

794 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.61 kDa

MYCNIKWLNRSLIYYGGAMSSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLADLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKEYFLREQMKAIQTELGDKEGKGGEVEELREKIEQSGMPEETMKAALKELDRYEKLPASSAESGVIRNYMDWLLALPWTDATEDMIDLAHSEEILNKDHYGLEKVKERVLEYLAVQKLTNSLKGPILCLVGPPGVGKTSLARSIATSLNRNFVRVSLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAKSVNPVFLLDEIDKMSNDFRGDPSAALLEVLDPEQNHNFSDHYIEEPYDLSKVMFVATANTLSSIPGPLLDRMEIISIAGYTELEKVHIAREHLLPKQLQEHGLRKGNLQVRDEALLEIIRYYTREAGVRTLERQIAKVCRKAAKIIVTAERKRIVVTEKNVVDLLGKHIFRYGQAEKTDQVGMATGLAYTAAGGDTLAIEVSVAPGKGKLILTGKLGDVMKESAQAAFSYIRSRAEELQIDPDFHEKNDIHIHVPEGAVPKDGPSAGITMATALISALTGIPVSKEVGMTGEITLRGRVLPIGGLKEKTLSAHRAGLTKIILPAENEKDLDDIPESVKENLTFVLASHLDEVLEHALVGVKQ

lon

Lon protease

794 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.19 kDa

MTENITINMPEIVPLYPLREIIAFPYMVFTIFLKQEDMPPFEEAVLFNNLVALVKLREEPTGELFPALHEIGTLCKVMQINKLAGGGAKVVLEGVIRVRLLAIVQQTPVALSRLEPVREFAEKSMVSEALVGSLNALLKIALSYGRPLPDDVMKMIDFIDNPARLSDLVALYLNLPIDELQKLLETVDPLERLKKVYMHLTNEVQRLQIKGEVQAEVTKKVGKSQKEFLLREQMKQIQEELGEEDSRLGEANELRSKVESAHMPEDVRRIAEKEMRRLERINPASPEYTVSRTYLDYLTTIPWQVSTPDNRDINQAETILNEDHYDLKKVKERILEYLAVRSLKDKMKGPILCFVGPPGVGKTSLGKSIARTLGRKFIRISLGGMRDEAEIRGHRRTYIGALPGRIIQEINRAGSNNPVFMLDEVDKIGADFRGDPASALLEVLDPEQNFSFTDHYLDVPFDLTNVMFITTANQLDPIPAPLKDRMEVITLSGYTDEEKLNIAKSYLVAREVEENGLASMAPQFTDEAIYRVTHDYTREAGVRNLQRNIASICRKIAKEVAQGKKARPIVNPETVSELLGAPKFFDEVASEKDRVGVATGLAWTESGGDIIFVEATKMKGKEDLILTGSLGEVMKESVRAALSFVKANCAELGIDKKMFDETTLHIHVPAGSIPKDGPSAGITMATAIVSLFSGRAARRDVAMTGEMSLTGRVLAIGGLKEKVLAARRAGVKKVLAPAKNKKDLEDIPENVKNELEFFFVEDIREVFVQALNPTSPAPTAATSARTPAGAPPPQ

lon

Lon protease

792 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.422 kDa

MEERELNQTQDIPEVLPILPLRETVVYPQMLIPLIVGREKSIRLVEDALSGNKLIGMCMQKTPVEDPTPDDIYRIGTVGIIVRSLRFPDNTLRLFVQGLQRIRVIEFLETEPYFKAKVEVIEEKVEKTVEIEGMMRNLLNLFQKMASLIPQFPEELLINAMNIQEPGRLADFIAFNTNLNINEKQEILETIDVKERLQKVTYYLTRELEILEIANKIQNEVKNEIEKSQKEYFLRQQMKAIQKELGEIDPREMEINELRQKLQEAKLPPEAMKEAERELERLSLMPPGSAEYTVTRTYLDWLISLPWAISTEDNLDIKRAEEILNEDHYDLEKVKERILEYLAVRKLKSDMKGPILCFVGPPGVGKTSLGKSIARALGRKFVRISLGGIRDEAEIRGHRRTYVGALPGRIIQGIRKAESNNPVFMLDEIDKLGSDFRGDPAAALLEVLDPEQNNAFVDNYLGVPFDLSKVMFIATANVLYTIPPALLDRMEVIELPGYTEYQKMGIAKGFLIPRQLKEHGLEKEQIEFSDDAIRKIIREYTREAGVRNLEREIASIIRKVAKGIAEGSITEKVIVKVEDVPKYLGPEKYTYGMKGEKDEVGVATGLAWTEAGGDILFVEALVVEGKGNLILTGKLGEVMQESAKTALSYVRSKLKDLNVSYELLEKADIHVHVPSGAIPKDGPSAGVTIATAIASALTRRPVKKDIGMTGEITLRGKVLPVGGIREKVLAAHRAGLTAVIMPKENKKDLEEIPEEVKKEITFYFVEHADEVLNLALLEVKESAEQRNPERIG

lon

Lon protease

792 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

86.499 kDa

MNGEQSANGARTLPDDAVVVVPVSNVIFPGVVFPIVLDRPSAVAAAQQALREQHPLVLVLQQDVQAPDPGPQSLHRMGTLANVLRYVTGPDGAPHVACQGVERFEIDEWVEGFPFLVARGRRIPEPEAEGAAIEARFLHLRSQALEALQLLPQSPPGELVAAVEGASSPAALADLVAAYLDLQPPEKQQILETIDLEARLDKVSAFLAQRLEVLRLTSEIAQRTRQSLGERQRETLLREQMAAIQRELGEGEREELVELEAAIENAGMPEEVVQQARKELRRLARTPEAAAEYGMVRTYLEWLVELPWGVPEAAPIDLAEARRILDEDHFGLEKIKQRIIEHLAVRRLAPEGKAPILCFVGPPGVGKTSLGQSIARAMHRPFVRVSLGGVHDESEIRGHRRTYVGALPGNIIQAIRKAGRRDCVMMLDEIDKMSAGIHGDPSAALLEVLDPEQNVAFRDNYLAVPFDLSRVVFIATANMLDTIPGPLRDRMEVIQLSGYTAGEKRQIAERYLVRRQLEANGLTAEQVQIEPAALETLIARYTREAGVRSLEREIGRLLRHVAVRFAEGHTEPVRIGPTNLEPILGPPRVENEVAMRTSVPGVATGLAWTPVGGEILFIEATRTPGDGRLILTGQLGEVMRESAQTALSLVKSRAEALGVTPSLFKESDIHIHVPAGATPKDGPSAGVAMTMALISLLTDRTVRSDTAMTGEISLRGLVLPVGGIKEKVVAAATAGVRRVLLPARNRADERDIPEETRQTLELIWLERIEDAIEAGLDPRRGDVRQTQVRAAS

lon

Lon protease

791 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.1 kDa

MQIEEIQNYPANLPVLVEDELFLYPFMITPIFINDSSNMKALDLAIKNDSMLFVAPSKLENGRNFDEIYNCGVIGTIMRKVPLPDGRVKILFQGYAKGKIIEQISNKPLEAKIELIKEDFLEGTKKEALLEVLKEKVKNLANISHYFSPDLLRTIEEGFDASRICDLILNTVRIKKQVAYEFFVLTDLEQKLVKLIDLIAQEIEANKIQKEIKNKVHSRIDKVNKEYFLKEQLRQIQKELGSDTQKEDEVREYQKRLELKKKFMHEDAYKEIKKQIEKFERIHQDNSEASMIQTYIETALDIPFEKISKKKLDIKEVSKQLNHDHYALNKPKERIEEYFAVRELLEKRKIAEKDGAKVILCLYGPPGVGKTSLANSVSKALKRELIRIALGGLEDVNELRGHRRTYIGAMPGRITQGLIEAKQINPVIVLDEIDKLNRSFRGDPSAVLLEILDPEQNSKFRDYYLNFNIDLSKVIFIATANDISNIPAPLRDRMEFIELSSYTPSEKFHIMKKYLIPDELKKHGLKSNELSIDDETIELIISDYTRESGVRNLRRKVAELCRKSAKKLLLENIKKVIINTKNLNEFLDKKVFEIEKNNGENQVGQVNGLAWTSVGGDVLKVEAVKIKGKGELTLTGSLGDVMKESARIAFSMIKVLIDEGKIKIPKKIIIDPKVNVYDSYNIHIHVPDGATPKDGPSAGITISTAIASIFSDKKVKADVAMTGEIDLKGKVLPIGGLKEKLIAAYKADIKTALIPRKNYERDLKDIPSEVRDNMEIIAVDTFSDVLEYTLV

lon

Lon protease

791 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

90.1 kDa

MQIEEIQNYPANLPVLVEDELFLYPFMITPIFINDSSNMKALDLAIKNDSMLFVAPSKLENGRNFDEIYNCGVIGTIMRKVPLPDGRVKILFQGYAKGKIIEQISNKPLEAKIELIKEDFLEGTKKEALLEVLKEKVKNLANISHYFSPDLLRTIEEGFDASRICDLILNTVRIKKQVAYEFFVLTDLEQKLVKLIDLIAQEIEANKIQKEIKNKVHSRIDKVNKEYFLKEQLRQIQKELGSDTQKEDEVREYQKRLELKKKFMHEDAYKEIKKQIEKFERIHQDNSEASMIQTYIETALDIPFEKISKKKLDIKEVSKQLNHDHYALNKPKERIEEYFAVRELLEKRKIAEKDGAKVILCLYGPPGVGKTSLANSVSKALKRELIRIALGGLEDVNELRGHRRTYIGAMPGRITQGLIEAKQINPVIVLDEIDKLNRSFRGDPSAVLLEILDPEQNSKFRDYYLNFNIDLSKVIFIATANDISNIPAPLRDRMEFIELSSYTPSEKFHIMKKYLIPDELKKHGLKSNELSIDDETIELIISDYTRESGVRNLRRKVAELCRKSAKKLLLENIKKVIINTKNLNEFLDKKVFEIEKNNGENQVGQVNGLAWTSVGGDVLKVEAVKIKGKGELTLTGSLGDVMKESARIAFSMIKVLIDEGKIKIPKKIIIDPKVNVYDSYNIHIHVPDGATPKDGPSAGITISTAIASIFSDKKVKADVAMTGEIDLKGKVLPIGGLKEKLIAAYKADIKTALIPRKNYERDLKDIPSEVRDNMEIIAVDTFSDVLEYTLV

lon

Lon protease

791 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.527 kDa

MKKPILISRAIVVLPYETTTIEVGRPKSIQAIDLAKQSSSKEIIIISQKDIDTDEVVNFDELYKVGTLVKIKSIIDNFDEGYSIEVEGLKAVYINNENDVIDAIEYEYEDVITNPILSNKDEIAINGINSEIFNIINKRSRHKNINFDNMHALISLEKEKFAYLAAATYINDYDNEISEKTIEDRINILLQPNLLLVHETILHLLFDQLVDKRVIEDEVEKTITDKINNNFQKQQREFYLREKLKVVKEQLGELSSREEDADKIRAKIEDLELPPNVKERALAELNRFENAMSSNESSVIKSYLDWLLDLPWTQQGVDNTDLMSVRTHLDDNHYGIEKVKERILEYLALRMRNPNLKGPIICLVGPPGVGKTSLVTSIAQALNKKFVKVSLGGVRDESEIRGHRKTYVGAMPGRIIKGMKKAGVINPLFLLDEIDKMTSDQRGDPAAAMLEVLDPEQNKNFSDNYIEEEYDLSKVMFMATANYYQQIPYALIDRLEVIELSSYTAIEKREIAKSHLLKRIFMDAKLNENELIFTDDALDFIINHYTKEAGVRELDRQLGHIVRKYIVETYKNKNNQSPLNLKVDEAMIIKYLGKIKFDFNKKEETTIPGIVNGMAYTAAGGDLLPIEVNHSTNGKGGNVTITGNLEKTMNESVSVALGFVKANADKYGIDTKKVSFKEIDIHVHVPSGGIPKDGPSAGIAITTAIISSLSQRPVRTTLSMTGEIMLRGNVGIIGGVKEKVISAYRAGVREIILPIDDERYLEDVPKYILDDIKIHLVKHYDEVYNIVFGEK

lon

Lon protease

791 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.748 kDa

MKTKSKKLKSDLSIGEFEDIFQEIPEQLPVVVISEIMPIPNVDFRIEVSDNSYLKALKESETNANSFVILLTQKGLSHNKPKLTNLQRYGVLAQIITKVKIPHGDFKVRFRILQRVKIDKFLQKEPFLKVSYEKVKTVYGSIEEEKALIKLVIEKIMDKPFQLLVQNTNNFLDIIKTEPETENITDIIIFNLKIDDLDKYKYLKESHLNKRIFYILQDIQSLLIGLDLEQKINEKVKQSIDENQKEFYLREKMKAIQLELGDKAKKEEEIAELRDKIKKTPLPPEIKKKALQELSRYQTSSLMAESFVIKNYLDFLLELPWGKTSQDENDLVAIEKSLNNQHYGLQKVKERILEYAAVKIMTKKNPQNILCLVGPPGVGKTSLASSIAKALGRQFVRQSLGGLKEESEIRGHRRTYIGAMPGRILAGIRDAKTVNPVFLLDEIDKLVTNYNFDPASALLEVLDPQQNINFMDHFLSEPFDLSQVLFIATANYLDNVPEALKDRMEIIEVSSYTEKDKINIASKYLLKKQLKNHGITDTNLVIDNDTILYLIRHYTKEAGVRELDRILAELARKTVKECLIKKKEQVIITTKNVTKYLGKEKYLNLLDEQKEKIGSTNGLAYTYFGGDLLPVEVTYYKGKGQLVLTGKLGEVLKESAYTALSFIKANCQNLGIDANIFAENDFHIHLPEAAIPKDGPSAGITIATSLVSAITQKYIKKGLGMTGEITLRGNILAIGGLKEKAIAANRSGLDTIFIPQENLKDIEDIPEEVRNKLNIIPVSNISDVFSQVFVV

lon

Lon protease

790 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.439 kDa

MEVPMPESTINEDSKIFKLPEILPIMPIFHTVAFPKMMFPMDIVGNRFIQLVDEAMAKDRLLGLVLTRKAPSAEGPLCQCEDLHRVGTCVSILKLAKQAGEKAQLVVQGLARFRIVEFLEEEPYIQARVEKIEADILIKDLEIEALMANLSTLFDRVIKLSPFLPQEFAAMAKSIQEPGDLADIIASIVNASVEDKQKILETLDIRQRLREITLIVNHQLEILELGSKIQSQVQEDIDKSQRDFYLRQQLKAIREELGESDENRVEVAEYRKKIEEKMLTEEARKEAFRELDRMSRMHPASAEYSVATTYLDWITSLPWNERTQDNQDIRQARRILDEDHYGLDKAKKRIIEYLAVRKLKPDTKGPILCFVGPPGTGKTSLAQSIARALGRKFYRISLGGVHDEAEIRGHRRTYVGALPGRIIQGIRRAESSNPVFVLDEIDKVGSDFRGDPSSALLEVLDPEQNFAFMDHYLGVAFDLSHVTFITTANILDTIPPALRDRLEVIELPGYTQDEKLRIAERYLIPRQREANGLTPEQIKFTRGAARLIISGYTREAGVRNLEREIAAVCRGVASQIAEGEISSALISARDIHRYLGPVRMISDARERISKPGIAMGLAWTPTGGDLLFVEATAMKGRKGLTLTGQLGEVMKESASAALSFIRSNAVKIGIPVDFFEETDIHIHVPAGAIPKDGPSAGVTMLAALASLLTNRTVKNDLAMTGEITLRGLVLPVGGIKEKVLAAHRAGIKTIILPKWNRKDLEEIPSKVRKEMNFVFVNDMREVLNIALSRK

lon

Lon protease

790 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.221 kDa

MAQVLNDISNRVLPLFPIRNTVLFPGLVLPILIGRDDSVKNLLRLGNDSENQHTILLTTQKNADDIKPSINSLYKIGVLAKITELVQLPNDNYKILIKVLDRVKLTIRRSHDLLVAEYVIVPDDEINNADEIKDKLANAIVLFNKYIRLSKKINPDLLVHVLSYTNQSYVVNALAANLICNVANKQSLLEITDVKQRIERLTDHVAKEIIIMETDELITSKAQKNLEKMQRDCFLNEKMKIIKNVLGVDDEKSDIAELQKKIDTLHLSKEAKAKAESELKKLKMMNPISAEAALTRNYLDILLGLPWKKEKESKININIDKALQDLNADHHGLEKVKERITEYLAVLQRTKKSIGTILCFIGPPGVGKTSLVKSIAEATKCKYAKFALGGVRDEAEIRGHRKTYIGAMPGKIISLIKRENSNNLVILLDEIDKISRDSRGDPAFALLEVLDPEQNSRFQDNYLEVEYDLSKVLFIATANSFNFPIPLRDRMEIIQIPGYVEGEKLEIAKHHLIPKQIKNNGLKNTEISFSDEAILELIRYYTREAGVRGLERKIGGICRKVLKKILSSKDIKSESVSKENIKDYLGSRKYKYGLAEDDNQVGITIGLAYTETGGDLIWVEAVMIPGKGKVKATGKLGDVMKESSQTAFSYFCSRAQKYNVKYEQYHKYDIHIHFPEGAIPKDGPSAGIAIFTTIVSLMTGIPVKLSVAMTGEITLRGRILPIGGLKEKLMAAKRGGIKTVIIPEGNTSDLEDIPNSIKNDLDIIPLSEADQVLDIALATTVTNSPAETAC

lon

Lon protease

787 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

89.254 kDa

MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQAMMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVKKIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILISLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKKITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEKIEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLEKVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVRDEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVLDPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNIAKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKYVEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNVLKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPKDGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITKVLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN

lon

Lon protease

784 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.

Belongs to the peptidase S16 family.

87.438 kDa

MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISALSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSIDDPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLKHIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFENKRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK

lon

Lon protease

784 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins, including some antitoxins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, UmuD and at least type II antitoxins CcdA, HipB and MazE (PubMed:8022284, PubMed:16460757, PubMed:22720069, PubMed:24375411). Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system (PubMed:15009896). Overproduction leads to very high persister cell formation (cells highly resistant to antibiotics), but not when 10 mRNA interferases are deleted, nor when Lon catalytic residues are mutated (PubMed:21788497).

Belongs to the peptidase S16 family.

87.438 kDa

MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISALSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSIDDPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLKHIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFENKRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK

lon

Lon protease

784 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.67 kDa

MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGINDLFSVGTVASILQMLKLPDATVKVLVEGLQRARISALSDNGDHFTAKAEYLTSPEIEEREQEVLVRTAINQFEGYIKLNKKIPPEVLTSLNSIDDAARLADTVAAHMPLKLSDKQSVLEMSDVDERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAARMPKEAREKTEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVEKDLQKRRQTLDTDHFGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNIAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKKHLLSKQIERNALKEHELIVDDSAIVGIIRYYTRERGVRSLERELSKLCRKAVKTLLMDKSVKHIEINADNLKDYLGVQRYDYGRADSENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARAEKLGINGDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPDENKRDLEEIPENVIADLDIHPVKRIEEVLALALQNAPYGMQVASVK

lon

Lon protease

784 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.071 kDa

MNKKSLPLMALRDMVVFPGVIAPIFVGRKKSLQALSRTTISEENNSKYILVTLQKKFDQENPSKHELYNTAILAKIIQIVKLPNNTAKILIEAVARVKLSNIKDEEAFEANYEIIPDEEILDIHNMRSLVDNAVQLFSKYAMNDKKVNAEIIETINKEISNRTNFINIINILSSHLITSLETKQQLLEETNPVKRITTVITTLTSNIVNSETEHALQQRVRKQIEKTQRDYYLHEQMKAIQKELDEDKSELADIEKKIKSLKLSKEAKEKAESEFKKLRAMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLVKSIAEGMGRKYTKFSLGGVRDEAEIRGHRKTYLGSMPGKILGQLKKIKTSNPVMLLDEIDKMSSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVVFIATANSHDLPRALSDRMEKIYISGYVEEEKLQIAKNYLVPKQFKMHKIKEDEITISEAAILDLIRYYTKESGVRALEREICALTRKALKQILANKTVKHISIDSNNLEEFLGAKKYNFGLAEKEDQIGSTTGLAYTEVGGELLTIEALAFSGKGEIKTTGKLGDVMKESAMAAYSCFRSRATNFGLKYDNYKDFDIHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVHRTVAMTGEITLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKENLEIISVSNIDQVLKHALVEMPINKGLSYDL

lon

Lon protease

784 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.102 kDa

MNKKSLPLMALRDMVLFPGVIAPIFVGRKKSLQALSRTTISEENNTKYILVTLQKKFDQENPSKHELYNTAILAKIIQIVKLPNNTAKILIEAVARVKLSDIKDEESFEANYEIIPDEEILDMHNMRSLVDNAVQLFNKYAMNDKKVNTEIIETINKEISNKTNFINIINILASHLITSLETKQQLLEETSPVKRITTVITTLTSNIVNSETEHALQQRVRKQIEKTQRDYYLHEQMKAIQKELDEDKSELADIEKKIKSLKLSKEAKEKAESEFKKLRAMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSNKIRGPILCLIGPPGVGKTSLVKSIAEGMGRKYAKFSLGGVRDEAEIRGHRKTYLGSMPGKILGQLKKVKTSNPVMLLDEIDKMSSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVVFIATANSHDLPRALSDRMEKIYISGYVEEEKLQIAKNYLVPKQFKVHKIKKDEITISEDAILDLIRYYTKESGVRALEREICALTRKALKQILADNTVKNISIDSNNLEEFLGAKKYNFGLVEKEDQIGSTTGLAYTEVGGELLTIEALAFSGKGEIKTTGKLGDVMKESAMAAYSCFRSRAPNFGLKYDNYKDFDIHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVHRTVAMTGEITLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKENLEIISVSNIDQVLKHALVEMPINKGLSYDL

lon

Lon protease

783 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Regulates swarmer cell differentiation of V.parahaemolyticus.

Belongs to the peptidase S16 family.

87.812 kDa

MNLERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSISCLETAMETNKQVLLVAQKQADTDEPTVDDLFEVGTVATILQLLKLPDGTVKVLVEGQQRAKINHFKESDFFLAEAEFIVTPELDEREQEVIVRSAINQFEGFIKLNKKIPPEVLTSLNGIDEAARLADTIAAHMPLKLVDKQQVLEIIDVTERLEFLMGQMESEIDLLQVEKRIRGRVKKQMEKSQREYYLNEQMKAIQKELGEMEDAPDEFETLQKKIDESKMPQEAREKTEQELQKLKMMSPMSAEATVVRSYIDWMVSVPWTKRSKVKKNLAKAEEILNEDHYGLERVKERILEYLAVQNRINKLKGPILCLVGPPGVGKTSLGRSIASATGRKYVRMALGGVRDEAEIRGHRRTYIGSLPGKLIQKMSKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNNSFNDHYLEVDYDLSDVMFVATSNSMNIPGPLLDRMEVIRLSGYTEDEKLNIAKRHLVEKQVQRNGLKPNEIVIEDSAIIGIIRYYTREAGVRGLEREISKICRKAVKNILLDKDIKSVTVTMDNLKEYLGVQRFDYGKADESNRIGQVTGLAWTEVGGDLLTIETQSMPGKGKLTQTGSLGDVMQESIQAAMTVVRSRADKLGINSDFYEKKDIHVHVPEGATPKDGPSAGTAMCTALVSALTGNPVKAEVAMTGEITLRGEVLPIGGLKEKLLAAHRGGIKTVLIPKDNERDLEEIPENVIADLQVIPVQWIDEVLKVALERDPTGVEFEAKK

lon

Lon protease

783 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.818 kDa

MDQEMVTKETEKYIELPLLASRGVVVFPHMVIPLLVGREKSIEALEKAMVKDKEIIILSQKDEKIEDPDPEDLYTIGTIAEVKQLVKLPNGMLKVVVEGIKRARIIDFIEIDEYFEVRAEILDQTVPEVDLEMKALMKAVLNKFQEYIKYNRNLPSETIMTVTNIEEPARFSDTIASHLELKFRQEQDLLEAISIKERLNKLLEIIKDEIEILKVEQKIQKKVRKQVEKTQKEYYLREQLKAIKEELDEDEEDDEIEEYRNKAEELDLPEKIREKVDKEIEKLKKTPSMSPEATVIRNYLDCVLDLPWNKVREEKIDLDEAKNVLDSEHYGLEDVKERILEYLAVRKLAPQKKSPILCLIGAPGVGKTSLGRSIARALGRDFVRLSLGGVRDEAEIRGHRRTYIGSRPGRIINAMREAGSKNPVFLLDEVDKMSSDFRGDPAAALLEVLDPEQNNEFTDHYLELPFDLSKVLFVTTANVAYPIPAPLLDRMEVIELPGYTEDEKVEIALRHLIPRILNEHGLTEDEIHFSSNSIYRIIREYTREAGVRNLERKLAAITRKVSKEIVEGRGRQARVTTQSIEKYLGVPKFKYEKAQKKDRVGVATGMAYTQTGGDILDIEVAVVPGKGKLTLTGSLGDVMKESARAALSYIRSKQEELGLSDNFHEEYDLHVHVPKGATPKDGPSAGITIASAIASALTGQPVKGKYAMTGEVTLRGRVLPVGGIKTKIMAARRAGLKDIIMPEENKKDFEEIPVKIKKDIRVNFVNHMDQVLDLILGGDEDEN

lon

Lon protease

781 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.389 kDa

MNNKKNEKTTNNKEIANVLVTRGIVFYPNTKIRIEIGREKSIAAINDSKEKKQNMIVVSQENPSIDSPSKNEIFTVGTLCSFEIDNKHPDGSYSIIFTGIKRVKINKLSEKASDGEIKTKFFYADYSEIEEDTKLSKSNEEAIKDLHAKFENELNNLTFFPKKDLALSKENRHTIVDWLPIALKFSLEEKQQLLEEPSLSKRIEKILSFTIDERVSQKIDSEISKKINTNLSKQQKEFYLRERVRAIKEELGDISSKEDDAESIRDRVRNNPYPEHIKKRILSEVNKLESSSNSNEYSMSKTYIDWLIDLPYWQKTDDVDSLADVENVLNNNHYGLEKVKERIIEYLAVRMKSKSAKGSIICLVGPPGVGKTSLAQSIAEALKKKFVKVSLGGMRDEAELKGHRKTYIGAMPGRIIKAMSKAGVVNPVFLLDEIDKLGSDHKGDPASAMLDILDPEQNNRFSDNYIEEDYDLSNVLFIATANYEENIPEPLHDRLEIIRLSSYTENEKLSIAKNYLVKKILVESALKKDELKFTDDGLSYIIKRYTREAGVREVERAIRQIARKFVVRQQKEKLTSQTIGVEEVKYYLKKEIYDYTKKDKEYMPGVVNGMAYTTAGGDLLPIEATFAPGKGKIEITGNLKETMKESVNVALGYVKTNAVKFGIDPKIFGEIDLHVHVPSGGIPKDGPSAGIALTTAILSALKNVKIPSNVAMTGEITLRGRVLIIGGVKEKTISAYRGGANDIFMPKEDERYLDDVPEEVRSKIKITLVDTYDDVYNRLFK

lon

Lon protease

781 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.29 kDa

MSTKFEKLEKLARESFQSPEVPETLPLIHLRNGMIIFPQTVVPVHVAREKTLLALEQSIESYQQFVFVTSQKDPSVEEPSFDQLYEIGTVSKVLQVVQLPDGSFRVLLEGLERARAYEVVQDNPFLVKLEILKVNYRKTKKLEALIRSVRESFAKYAYYTQRYSQETLSAMSEISDANRLADFVASLLPLQLKQRQSLLEQLKPAKRLEMILEILSHENEILEIERELDTKVKKRIEENQKEFFLREKLKAITEELGEKDTEADQLKARLQKLKLPEHAKQKATLEIERLEKMSPYSAEATVIRTYLDWLFNLPWDNSTEDRQDISQAEKILQASHYGLKEAKERILEFLAVRKRSNSVKAPILCFVGPPGVGKTSLARAVSQALNRKFAHMSLGGLRDEAEIKGHRRTYVGAMPGRILQLIRTAQSKNPVLLLDEIDKMAVSFQGDPAAALLEVLDPEQNKEFVDHYLEIPFDLSNVLFITTANVTHTIPPALLDRMEIIELEGYTDYEKSIIARQYIIPKLMGENALNEATFKITQGAIKKIIHTYTREAGVRQLTRMLQRLMRKSALKIEQGAKSVVIKSKDLEHFLGPQPVQNDIMLSKPEIGAVHGLAWTEYGGVVMVVESLLMPGKGDLILTGRLGEVMRESARIALSVARSFCGQDCKEKFQQSDIHINLPEGAVPKDGPSAGITMTVAMISSVLGKPVRNDTAMTGEITLRGKILAVGGVKEKILAAHRHGIKRILLPKTNEKDLKRIPPQVKDKMEFIFVEDIEKAVEKSCS

lon

Lon protease

780 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.203 kDa

MNPERSEYIEIPVLPLRDVVIYPYMVIPLFVGRDKSIKCIEASMNKNKKIMLVTQKEAEIDEPTDNDLFTIGTTASILQMLKLPDGTVKVLVEGLQRAKVKKINNENGYFTAQIQLICTPEITEKEQSILIRTTLNQFENYVKFNKKISPEILNSLNNITNASQLSDMIAIHMPLKLSEKQSILETYNTNERLERLMAIMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDETLDEHEILKRKITTIKMPKEAQEKMASELHKLKMMSPMSAEATVVRSYIDWMIQIPWNIRSKVKKNLTQAQKILDSDHFGLDKVKERILEYLAVQSRINTVKGPILCLVGPPGVGKTSLGQSIARATGRKYIRMALGGIRDEAEIRGHRRTYIGSMPGKIIQKMAKVGVKNPLFLLDEIDKMSCDIRVDPASALLEVLDPEQNVAFNDHYLEVDYDLSNVMFIATSNSTNIPAPLLDRMEIIRISGYTEFEKLNIAKSYLKPKQIKRNALKSNELTIEDSVVTNIIRYYTREAGVRNLERELSKICRKCVKNLILNKSLKKIKITTDNLHDYLGIKKYDFGKTNYKNQIGQVIGLAWTEVGGELLTIEAACISGKGKLIYTGSLGEVMQESIQAALTVVRSQANKLGIKKNFYEKNDIHVHVPEGATPKDGPSAGIAMCTAIVSCLTGIPVKSDIAMTGEITLRGQILTIGGLKEKLLAAHRGGIKKVLIPYDNEKDLQEIPKTILKGLFVHPVKHIKEVLNLSLENTPYFSSK

lon

Lon protease

780 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.203 kDa

MNPERSEYIEIPVLPLRDVVIYPYMVIPLFVGRDKSIKCIEASMNKNKKIMLVTQKEAEIDEPTDNDLFTIGTTASILQMLKLPDGTVKVLVEGLQRAKVKKINNENGYFTAQIQLICTPEITEKEQSILIRTTLNQFENYVKFNKKISPEILNSLNNITNASQLSDMIAIHMPLKLSEKQSILETYNTNERLERLMAIMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDETLDEHEILKRKITTIKMPKEAQEKMASELHKLKMMSPMSAEATVVRSYIDWMIQIPWNIRSKVKKNLTQAQKILDSDHFGLDKVKERILEYLAVQSRINTVKGPILCLVGPPGVGKTSLGQSIARATGRKYIRMALGGIRDEAEIRGHRRTYIGSMPGKIIQKMAKVGVKNPLFLLDEIDKMSCDIRVDPASALLEVLDPEQNVAFNDHYLEVDYDLSNVMFIATSNSTNIPAPLLDRMEIIRISGYTEFEKLNIAKSYLKPKQIKRNALKSNELTIEDSVVTNIIRYYTREAGVRNLERELSKICRKCVKNLILNKSLKKIKITTDNLHDYLGIKKYDFGKTNYKNQIGQVIGLAWTEVGGELLTIEAACISGKGKLIYTGSLGEVMQESIQAALTVVRSQANKLGIKKNFYEKNDIHVHVPEGATPKDGPSAGIAMCTAIVSCLTGIPVKSDIAMTGEITLRGQILTIGGLKEKLLAAHRGGIKKVLIPYDNEKDLQEIPKTILKGLFVHPVKHIKEVLNLSLENTPYFSSK

lon

Lon protease

779 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

83.676 kDa

MAEAKTVPVLFLNDSIVLPGMVVPIELDDAARAAVDAARASESGELLIAPRLEDRYPAYGVLASIVQIGRLPNGDAAAVVRGERRAHIGSGTSGPGAALWVQVEEVTDPEPTDETKKLAGEYKKLLLAMLQRRDAWQIVDMVNKITDPSALADTAGYASYLTGTQKRELLETTDVDRRLSLLIGWTGDHLAETEVNDKIAEDVRTGMEKQQKEFLLRQQLAAIRKELGELDDNGDGSSDDYRARIEQADLPEKVREAALREVGKLERASDQSPEGGWIRTWLDTVLDLPWNVRTEDSTDLARAREILDTDHHGLSDVKDRIVEYLAVRGAAPQRGMAVVGGRGSGAVMVLAGPPGVGKTSLGESVARALDRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAIGEAGSMNPVVLLDEIDKVGSDYRGDPAAALLEVLDPAQNHTFRDHYLDLDLDLSDVVFLVTANVIENIPSALLDRMELVEIDGYTADDKLAIAQGFLLPRQRERGGLTSDEVTVTEAALRKIAADYTREPGVRQFERLLAKAMRKAATKLADHPQAAPITIDEPDLVEYLGRPRFLPESAERTAVPGVATGLAVTGLGGDVLYIEANSTEGEPGLQLTGQLGDVMKESAQIAMSYVRAHAKQLGVDPEALNRRIHIHVPAGAVPKDGPSAGVTMVTALVSMATGRKVRGDVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPQRNQPDLDDVPADVLDALDVRPMTDVADIIAAALEPAHEASTAAAA

lon

Lon protease

779 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.422 kDa

MGERSGKRELPLLPLRGLLVYPTMVLHLDVGREKSIRALEQAMVDDNKILLATQEEVHIEEPDAEQIYSIGTVARVKQMLKLPNGTIRVLVEGLQRAKIEEYLQKEDYFVVSITYLKEEKAEENEVEALMRSLLTHFEQYIKLSKKVSPETLTSVQDIEEPGRLADVIASHLPLKMKDKQEILETVNIQERLEILLTILNNEREVLELERKIGNRVKKQMERTQKEYYLREQMKAIQKELGDKDGRQGEVDELRAQLEKSDAPERIKAKIEKELERLEKMPSTSAEGSVIRTYIDTLFALPWTKTTEDNLDIKHAEEVLDEDHYGLEKPKERVLEYLAVQKLVNSMRGPILCLVGPPGVGKTSLARSVARALGREFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMKQAGTINPVFLLDEIDKLASDFRGDPASALLEVLDPNQNDKFSDHYIEETYDLTNVMFITTANSLDTIPRPLLDRMEVISISGYTELEKLNILRGYLLPKQMEDHGLGKDKLQMNEDAMLKLVRLYTREAGVRNLNREAANVCRKAAKIIVGGEKKRVVVTAKTLEALLGKPRYRYGLAEKKDQVGSVTGLAWTQAGGDTLNVEVSILAGKGKLTLTGQLGDVMKESAQAAFSYIRSRASEWGIDPEFHEKNDIHIHVPEGAIPKDGPSAGITMATALVSALTGIPVKKEVGMTGEITLRGRVLPIGGLKEKCMSAHRAGLTTIILPKDNEKDIEDIPESVREALTFYPVEHLDEVLRHALTKQPVGDKK

lon

Lon protease

778 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.599 kDa

MNQENKVLPLIPLRGLIVFPYMVVHFDVGRDKSIEALEKAMMNDQQIFLSTQKDAKIEEPNEDDINSVGTICSIKQILRLPGDAVRVLVEGISRGKIDKYLKQEPFIEAEITEFKDEDNYEEYEIKALMRIITKEFGKYVKLSGAVTKDAVDFLKDIKEPGKFADIVSSYLIIKQEQKQSVLNSIDEKERLENVLTVIKDELQILELERNIGVKVKEKIDKSQREYYLREQIKVMQDQLGDDDEEKAEIKEYTQKIKKGKLTKEAKEKALHELKKLENAGAYSPEGAGIKTYLDWILSLPWKDKTKDNLDIKRAREILNKEHYGLSDVKDRIIEYLAVKKMSKSLKGPILCLVGPPGVGKTSIAKSIANAVNRNFVRISLGGVNDEAEIRGHRRTYVGAIPGRIIYGMKQAKSNNPLMLLDEIDKMSSSYKGESADALLEVLDTSENNKFRDNYLELDFDLSDVMFVTTANTLETIPRPLMDRMEIIEVSGYTYEEKFHIAKEHLIPKQLEEHNMPEDKKITFMDSSIYYIIENYTRESGVRSLERKIAAIIRKIITEIVEKDKSSISVNSRTVKKYLGEDVFSADKIDKEDKIGVVTGMAWTAYGGDTLPVEAVIMPGNGKLQLTGQLGDVMKESAQAGYSYVRANSVKYGIDKEFYKNKDIHVHVPEGAVPKDGPSAGVTMITAMVSALSDKKVKHNVAMTGEITLTGRVLAIGGLKEKTLAAYRAGVDTIIIPKQNEKDINKVPKAIRGKIKFILAEEVDTVLENALIGGINNDN

lon

Lon protease

778 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.599 kDa

MNQENKVLPLIPLRGLIVFPYMVVHFDVGRDKSIEALEKAMMNDQQIFLSTQKDAKIEEPNEDDINSVGTICSIKQILRLPGDAVRVLVEGISRGKIDKYLKQEPFIEAEITEFKDEDNYEEYEIKALMRIITKEFGKYVKLSGAVTKDAVDFLKDIKEPGKFADIVSSYLIIKQEQKQSVLNSIDEKERLENVLTVIKDELQILELERNIGVKVKEKIDKSQREYYLREQIKVMQDQLGDDDEEKAEIKEYTQKIKKGKLTKEAKEKALHELKKLENAGAYSPEGAGIKTYLDWILSLPWKDKTKDNLDIKRAREILNKEHYGLSDVKDRIIEYLAVKKMSKSLKGPILCLVGPPGVGKTSIAKSIANAVNRNFVRISLGGVNDEAEIRGHRRTYVGAIPGRIIYGMKQAKSNNPLMLLDEIDKMSSSYKGESADALLEVLDTSENNKFRDNYLELDFDLSDVMFVTTANTLETIPRPLMDRMEIIEVSGYTYEEKFHIAKEHLIPKQLEEHNMPEDKKITFMDSSIYYIIENYTRESGVRSLERKIAAIIRKIITEIVEKDKSSISVNSRTVKKYLGEDVFSADKIDKEDKIGVVTGMAWTAYGGDTLPVEAVIMPGNGKLQLTGQLGDVMKESAQAGYSYVRANSVKYGIDKEFYKNKDIHVHVPEGAVPKDGPSAGVTMITAMVSALSDKKVKHNVAMTGEITLTGRVLAIGGLKEKTLAAYRAGVDTIIIPKQNEKDINKVPKAIRGKIKFILAEEVDTVLENALIGGINNDN

lon

Lon protease

778 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87 kDa

MHKKSLPLMALRDMVVFPGVIAPIFVGRPKSLQALSHTTISEEDNSKYILVTLQKKFDQENPSTHELYNTAILAKIIQIVKLPNNTAKILIEAVARVKLSNIKGEEAFEANYEIIPDEEIFDVNNMRSLVDNAVQLFSKYAINDKKVNAEIIETINKEISNSTNFIDIINILASHLITSLEAKQHLLEETSPFKRITTVISMLNSNIVNSETEQALQKRVRKQIEKTQRDYYLHEQMKAIQKELDEDKSELADIENKIKSLKLSKEAKEKAEAELKKLRTMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLVKSIAEGMGRKYTKLALGGVRDEAEIRGHRKTYLGSMPGKILGQLKKVKTSNPVMLLDEIDKMSSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVIFIATANSHDLPRALSDRMEKIYISGYVEETKLQIARNYLVPKQFKMHKIKKDEITISETAILDLIRYYTKESGVRALEREIGALTRKALKQILADKSVKHIAIDSNHLEEFLGAKKYNFGLAEKEDQIGSTTGLAYTEVGGELLTIEALAFPGKGEIKTTGKLGDVMKESAMAAYSCFRSRATNFGLKYDNYKDFDIHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVHRTVAMTGEITLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKESLEIISVSNIDQVLKHALVGTPINK

lon

Lon protease

778 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.027 kDa

MNKKSLPLMALRDMVVFPGVIAPIFVGRQKSLQALSHTTVSEEDNSKYILVTLQKKFDQENPSKHELNNTAILAKIIQIVKLPNNTAKILIEAVARVKLSNIKGNDAFEANYEIIPDEEIFDVNNMRSLVDNAVQLFSKYAINDKKVNAEIIETINKEISNSTNFINIINILASHLITSLEAKQHLLEETSPFKRITTVISTLTSNIVNSETEQALQQRVRKQIEKTQRDYYLHEQMKAIQKELDEDKSELADIEKKIKSLKLSKEAKEKAESELKKLRSMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLVKSIAEGMGRKYTKFALGGVRDEAEIRGHRKTYLGSTPGKILGQLKKVKTSNPVMLLDEIDKMSSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVIFIATANSHDLPRALSDRMEKIYISGYVEEEKLQIAKNYLVPKQFKMHKIKKDEITISETAILDLIRYYTKESGVRALEREIGALTRKALKQILADKTVKHIAIDSSNLEEFLEAKKYNFGLAEKEDQIGSTTGLAYTEVGGELLTIEALAFPGKGEIKTTGKLGDVMKESAMAAYSCFRSRATNFGLKYDNYKDFDIHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVHRTVAMTGEITLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKESLEIISVSNIDQVLKHALVETPINK

lon

Lon protease

778 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

82.739 kDa

MATLPVLPLTDAVLLPGMAIPVTLDPTTQAAVDAARATGDQRLLAVPRLDGEYGPVGVVATIEKVGRLPSGEPAAVVRGLARARIGSGVPGPGAALWVEAAELAEPAPAGRARELAREYRALMTSVLQQRGAWQVIDAIERMTDLSELADSAGYVSWLSLAQKTELLAAPDVTTRLELLVGWVRAHLAEQEVAEQINTDVREGLEKSQREFLLRQQLATIRKELGEDEPEGSADYRARVEAADLPAPVRDAALREVGKLERASDASPEAGWIRTWLDTVLEMPWNTRTEDNTDLVAARAVLDADHAGLTDVKDRILEYLAVRNRRVERNLGVVGGRGSGAVLALAGPPGVGKTSLGESVARALGRRFVRVSLGGVRDEAEIRGHRRTYVGALPGRIVRALREAGSMNPVVLLDEVDKLAVGYSGDPAAALLEVLDPAQNHTFRDHYLEVDLDLSDVLFLATANVVEAIPSPLLDRMELVTLDGYTEDEKVAIARDHLLPRQRERAGLTADEVTISDGVLARIAGEYTREAGVRQLERSLAKIFRKVAVTATTDPAPVHVDTGNLHRYLGRPKFSPESAERTAVPGVATGLAVTGAGGDVLFVEATSMAGEPGLTLTGQLGDVMKESAQIALSYLRSNGRRLGLDPNALAGRRIHLHVPAGAVPKDGPSAGITMVTALASLVSGRPVRPEFGMTGEVTLSGRALPIGGVKQKLLAAHRAGLTEVIIPQRNEPDLDDLPAEVREALTVHTLADVADVLALALRPADLDADSLDGEALATA

lon

Lon protease

777 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.033 kDa

MNSERSERITIPVLPLRDVVIYPHMVIPLFVGRQKSIKCIETSMSNDKKIMLIAQKEASKDEPTPKDLFDIGTISAILQMLKLPDGTVKVLIEGLQRAHIKNLTNNGEHFIAEVELISSSNLLDKNQEVLIRTTMNQFESYIKLNKKIPLEILNVLNNIKNSEKLADTIAAHMPLKLNDKQSVLEIRNINDRLEFLMAIMESEIDLLQVEKRIRHRVKKQMEKSQREYYLNEQIKAIQKELGDMDEIPDENKILKRKIKSSKMPKEAREKTELELQKLKMMSPMSAEATVVRSYIDWMIQVPWYLKTKIKKDLQQAKKILDIDHFGLETVKDRILEYLAVQSRKNKIKGPILCLIGPPGVGKTSLGKSIARSTGRKYVRIALGGIRDEAEIRGHRRTYIGSMPGKLIQKMAKAKVKNPLFLLDEIDKMSRDIRVDPASALLEVLDSEQNMNFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEIIRLSGYTEDEKLNIAKRYLYPKQIERNGLEENEIKITDSAIISIIHYYTREAGVRSLEREISKICRKAVKNLILDKSLKHIEINSKNLKKFLGIKRFDYGKIHGTNQIGQVIGLAWTEVGGELLTIETTCVSGKGKLTYTGSLGEVMQESIQAALTVVRSQADRLGIKKDFHEKHDIHVHVPEGATPKDGPSAGAAMCTAIVSSLTNNPVKSNVAMTGEITLHGKILPIGGLKEKLLAAHRGGIKTVLIPYENKRNLEEIPKNIIEGLNIHPIKKIEEVLKLSLEKIPYV

lon

Lon protease

777 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.755 kDa

MNSERSERIKIPVLPLRDVVVYPHMVIPLFVGRKKSIHCIETSMNNDKKIMLIAQKEASKDEPSTNDLFNIGTISSILQMLKLPDGTVKVLVEGLQRACIKNIESNGEHLVAEVELIISPTVIDKEQEVLIRTTVNQFESYIKLNKKIPSEILNTLSQTKNAEKLADTIAAHMPLKLADKQSVLEIYNVNERLEFLMAIMETEIDLLKVEKRIRNRVKKQMEKSQREYYLNEQIKAIQKELGDMDEIPDENKILKRKIKSLKMPKEAKEKTESELQKLKMMSPMSAEATVVRSYIDWMIQVPWNIKTKIKKDIQEAKKILDIDHFGLEKVKERILEYLAVQSRTNKVKGPILCLIGPPGVGKTSLGKSIAKSTGRKYVRMALGGIRDEAEIRGHRRTYIGSMPGKLMQKMVKAKVKNPLFLLDEIDKMSCDIRVDPASALLEVLDPEQNINFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEIIRLSGYTENEKLNIAKCYLYPKQMERNALKRNELIITDCAIISIIQYYTREAGVRSLEREISKICRKVVKLLILNKSLKKIEINSKNLKKFLGIKRFDYGKTNNLNQIGQVVGLAWTEVGGELLTIETACVSGKGKLTYTGSLGEVMQESIQAALTVVRSQAKKLGIKKDFHEKHDIHVHVPEGATPKDGPSAGIAMCTAIVSSLTKNPVKSNIAMTGEITLQGRVLTIGGLKEKLLAAHRGGVKTVLIPYENKRNLEEIPKNIIEGLTIYPVKNIEEVLKIALENTPYV

lon

Lon protease

776 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

87.866 kDa

MKEYYTISEKKLPIIALRGLWLFPNNIQHFEVGREVSLNALNASLLRNSEIFICTQKDPMLENITKEDFYHTGVLASIKQTIKMPNGNIRVLVEAYDRAKIVDFVENDSFLEANVEVMEYDKTKYHPTDKSLTMIRMIISSFESLAEIIKKPLPQDLLGGLLNEEDPSSLIDTIAMLISLNDKDSILLLETLDMDERIELVYKFVIKEIEFLKIKEDIEERTNKEISDTQKEYFLQEQLRQIKMELGEEYDIEDTDDYANRVKKLKLKKDSEEHVLKEINRLSSMNPNNPESTVIRNYIDQVLDIPWNKKSKSSIDLKVAEKVLNDGHFGLEDVKKRILEYLAVKKMTGSLKGPILCLVGPPGVGKTSIARSIADATNRKFVSMRLGGVRDEAEIRGHRKTYIGAMPGRIITQLQKAKKLNPVFLLDEIDKLASDFRGDPASALLEVLDPEQNSEFTDNYIEIPVDLSDVLFITTANSQEQIPDALLDRMEVIRVTSYTDSEKFEIANRYLLPRQLKENGMDKSQFHITRDAIYTIINNYTRESGVRELERNIGKVIRKAVVKIVKDDVKKVVVNNKNLEKFLGSKLVLDDEIPREDTVGVVNGLAWTQVGGVILTIEANVMDGSGKTQLTGKLGDVMKESAMAAISYIRSNQEALGIKGEFYKEKDIHIHVPEGAVPKDGPSAGVTMVTALVSALTGRKVKHDFAMTGEITLTGRVLAIGGVKEKVLAAHRYGINKVFLPKENKRDIQDIDPKIRQKIKFYFTSNVKEILDEVLI

lon

Lon protease

775 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

86.722 kDa

MNKKSLPLMALRDIVVFPGVIAPVFVGRQKSLHALSNTTLSEEDNSKYILVTLQKKFDQENPNRNELYDVGILAKVIQIVKLPNTTAKILVEAIARVKISNIKGDEAFEANYEIIPDEEIFDANNMRSLVDNAVQLFAKYAGSDKKINAEIIETINKEISETSNFINIINILASHLITSLEEKQRLLEETSPFKRISTIINILTSNIVNSETEQALQQRVKKQIEKTQRDYYLHEQMKAIQKELDEDKSDLAEFDKKIKAAKLSKEAREKAEAELKKLRTMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLIKSIAEGMGRKYTKFALGGVRDEAEIRGHRKTYLGSMPGKILTQLKKVKTSNPVMLLDEIDKMGSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVIFIATANSYNLPRALIDRMEIIDISGYMEEEKIQIAKNYLVPKQLKMHKIKKDEITISDDAILDLIRYYTKESGVRSLEREIGALTRKALKQILADKKVKHISVDSNNLEEFLGARKYNFGLAEKNDQIGSTTGLAYTEVGGELLTIEALSFPGKGEIKTTGKLGDVMKESAMAAYSCFRSRAADFGLKYEDYKDFDVHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVRRTVAMTGEVTLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKSSLEIIPVSNIDQVLEHALTKKT

lon

Lon protease

774 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.114 kDa

MMIAVTKRTIPVIPLRGLVVFPYMMLHFDVGRQISLKALEEAMNSDQQVLLLAQKDPKQEEPSPEDLYQYGTVAKIKQMLKLPSETSRILVEGLSRAKVIGYVSVDPYFLVEVEEYKEKGGNLDDPELEALIRNVVSAFEEYARLTSRIPPDAILSVTTIQNPGQLADVIAANVIVKLEDKQLLLEQVDLKERLTKLYELILREKEIIEIERKITIKVKKQIDKMQKEYYLREQLKAIQSELGEKDSLFSEAQEYREQVQKLGLSNENLQKVYKEIDRLEKLPPNSPEIGVIRTYLEWIIDLPWNVKSEEKIDINVVKNVLDEDHYGLTKVKERILEYIAVRKLKNNLKGPILCLVGPPGVGKTSIAKSIARALNRNYVRISLGGLRDEAEIRGHRKTYVGAMPGRIIYALRQAKTKNPLILLDEIDKMSQDFRGDPASALLEVLDSEQNYAFRDHYVEIPFDLSEVMFIATANTLETIPRPLLDRLEVIEITGYTEEEKVEIAKRYLFPKQIEQNGLKKSQIRYDEAVIRDIISFYTRESGVRNLEREIARLCRRVAKEILEENKKMVRITTRNLEKYLGVRKYRRDELIEEDRIGIVTGLAWTPFGGETLSVEALVMPGSGKLELTGQLGDVMKESAKAAVSIIRARAKELGIDENFYKEYDIHIHVPEGAIPKDGPSAGVTMATAMVSALSKKPVRHDVAMTGEITLSGRVLPIGGVKEKILAAKRVGIKNVILPYENKKDVDELEDYVKKDMNFVFVKAIDEVFKIAIKE

lon

Lon protease

774 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

88.114 kDa

MMIAVTKRTIPVIPLRGLVVFPYMMLHFDVGRQISLKALEEAMNSDQQVLLLAQKDPKQEEPSPEDLYQYGTVAKIKQMLKLPSETSRILVEGLSRAKVIGYVSVDPYFLVEVEEYKEKGGNLDDPELEALIRNVVSAFEEYARLTSRIPPDAILSVTTIQNPGQLADVIAANVIVKLEDKQLLLEQVDLKERLTKLYELILREKEIIEIERKITIKVKKQIDKMQKEYYLREQLKAIQSELGEKDSLFSEAQEYREQVQKLGLSNENLQKVYKEIDRLEKLPPNSPEIGVIRTYLEWIIDLPWNVKSEEKIDINVVKNVLDEDHYGLTKVKERILEYIAVRKLKNNLKGPILCLVGPPGVGKTSIAKSIARALNRNYVRISLGGLRDEAEIRGHRKTYVGAMPGRIIYALRQAKTKNPLILLDEIDKMSQDFRGDPASALLEVLDSEQNYAFRDHYVEIPFDLSEVMFIATANTLETIPRPLLDRLEVIEITGYTEEEKVEIAKRYLFPKQIEQNGLKKSQIRYDEAVIRDIISFYTRESGVRNLEREIARLCRRVAKEILEENKKMVRITTRNLEKYLGVRKYRRDELIEEDRIGIVTGLAWTPFGGETLSVEALVMPGSGKLELTGQLGDVMKESAKAAVSIIRARAKELGIDENFYKEYDIHIHVPEGAIPKDGPSAGVTMATAMVSALSKKPVRHDVAMTGEITLSGRVLPIGGVKEKILAAKRVGIKNVILPYENKKDVDELEDYVKKDMNFVFVKAIDEVFKIAIKE

lon

Lon protease

774 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

85.998 kDa

MSEVLNVVPVIPLRDVVIYPSMTLPLNVGRKKSIEAVKQASNSYNNYILLATQKNGSSSGDVVDNIYDIGTLAKVVQIMKLPDGSLKIIVEGIAKRLVAKYESIDGCIYANLDSLHIDDNYDPSQIDKELKAILLSITDSLKKFVDISGKVSKESLATLINTEEPHKFIYEISTILNTEIAKKQKILEATDIKNKALLLLSCLYEELEILELEAKIKDRVKSQVDKNQREYYLNEQVKAIYKELGEADEESEVTALKSRIEATKMSKEAKEKCLKELKKLKAMPPSSSESAVSRNYIETILSLPWGKKAKVKKDINLAEKVLEKDHYGIKKVKERILEHLAVQIKRDTNAKAPILCLVGPPGVGKTSIGQSIARATGREYVRMALGGVRDESEIRGHRRTYIGSMPGQIIQKIIKSKTENPLFLLDEIDKISSDFRGDPSAALLEVLDPEQNSTFNDHYLEIDYDLSKVMFVATANSLDIDPALRDRLEIIHLSGYTEIEKQAIAKQYLVPKALENNGLTKNEINFTPKATLDIIRYYTREAGVRNLQQKIDGVCRKAVKNLLKDPEHGKVSITQNNLEDYLGVHQFDYGIKNAKPKVGQVTGLAWTSVGGELLTIEALAMPGKGKVKYTGSLGDVMKESIDAAFSVVRSISKDYKLEDDFYEKKDIHIHVPEGATPKDGPSAGIAMTTALVSVYTNKPVRNDIAMTGEVTLRGDVLAIGGLKEKLLAALRGGIKEVLIPKQNVKNLADVDKEILEKLEITPVNSIKEVLERVF

lon

Lon protease

772 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

86.604 kDa

MENNAYPTLPLKNTVLFPHLVLPLSVGRAGSIAAVEAALSSEDKLIAVFPQKDPRTDEPAADDLFRFGTVGIIKKMVRSEDTVQILVQGIERVEQLEMVQKQPYLSLKIATLSEPSDTGTEIEALHRTVIELAGKMIELVQPQIQVGIHHIISDVEKPLHQIYLLTSILSLDFDKEKELLAAATQVEALQLMHRYLNHEVQVLEVRQKITSTAQTEIDKKQREYVLRQQLEAIQEELGETNPEQAEIKELRQRMEETELPELVRKEVEKEITRLERMPSAAPDYQLTRGYVELALELPWNKTTEDRLDLKRAREILDEDHFDLEDVKERIIEHLAVMKLNPEAKSPILCFVGPPGVGKTSVGQSMARALGRKFERMSLGGLHDESELRGHRRTYIGAMPGRIIRAIRRTGYQNPLLMLDEIDKLGRDFRGDPAAALLEILDPAQNAEFHDNYLDLPFDLSKIFFVTTANTLDTIPRPLLDRMEILRLPGYSDEEKQHIARRYLIGRQIREAGLSEIQLSIPDETLSYLIRRYTREAGVRELERMLGRIARKVATQVATGQTQPVTVTPQDLVELLGPERFFAEEMRQQLAPGVAAGLAWTEAGGDVLYVEAALLPEGKGMTLTGQLGSIMQESAKAAQSYLWSRAEELNIDQKTIRESGVHIHVPAGAIPKDGPSAGVTMASALTSAYAHQPVRSDTAMTGEITLSGLVLPVGGIKEKVLAAHRSGIQRIILPKENEKDLREIPEHVRQSIQFILARRIEEVLAEAIPDLNR

lon

Lon protease

768 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

85.999 kDa

MSEKLPVIPLKNVVMFPGIVLPLLIGRPKSIKALEEAMKGTKQVILLAQKDENIDEPAPSDLYDVGVIGEVIQIFRAPDGTVRMVVEAKTRVKASVSDSGEFLEGNYEVLEEVEGDATRTEALVKATIARFEEYARLSGRIPIEVVAGIGGLDNPGKIADMVAANMFISYYEKQKVLELLSIPERLEHVLQLLLREIEVLKLSQEIEETVRERMEKNQREYILREQLKAIQEELGEKDERTIEIEQYKKRIEESGMPEEARKKAEEELDRLQRMPPYSAELAVIRTYLDWLVSLPWNARTEDEDDLKTVKQKLDKSHYGLDDAKERIVEFIATKKLSSNPKAPILCLVGPPGVGKTSLAKAIATALNRKLVRISLGGIRDEAEIRGHRRTYVGAMPGRIIQGIRSAGTKNPVFVLDEIDKLSSDFLGDPSAALLEALDPEQNYAFQDHYLEVPFDLSEVFFITTANNLYTIPPALLDRMEVIRVPGYTEEEKLHIAKDFILPKLYEQSGLNPEEVSFSDQAIIRIIREYTREAGVRNLERNLLSILRKLAVEKLEKGFSRVRITVKNVEDYLGVPKFRYGKALEKPEIGVVAGLAWTEFGGETMLIECQVVKGKGQLILTGSLGQTLKESAMAALTYVRSRAKQLGIDEEFYKKYDIHVHAPEGAIPKDGPSAGITIATAMISALKKEPVPNDLAMTGEITITGKVLPIGGVKEKVLAAHRIGLDRVILPKDNKINMEEIGDEVKKKLRFYFVDTMDQVVEIVFGKTS

lon

Lon protease

768 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

85.999 kDa

MSEKLPVIPLKNVVMFPGIVLPLLIGRPKSIKALEEAMKGTKQVILLAQKDENIDEPAPSDLYDVGVIGEVIQIFRAPDGTVRMVVEAKTRVKASVSDSGEFLEGNYEVLEEVEGDATRTEALVKATIARFEEYARLSGRIPIEVVAGIGGLDNPGKIADMVAANMFISYYEKQKVLELLSIPERLEHVLQLLLREIEVLKLSQEIEETVRERMEKNQREYILREQLKAIQEELGEKDERTIEIEQYKKRIEESGMPEEARKKAEEELDRLQRMPPYSAELAVIRTYLDWLVSLPWNARTEDEDDLKTVKQKLDKSHYGLDDAKERIVEFIATKKLSSNPKAPILCLVGPPGVGKTSLAKAIATALNRKLVRISLGGIRDEAEIRGHRRTYVGAMPGRIIQGIRSAGTKNPVFVLDEIDKLSSDFLGDPSAALLEALDPEQNYAFQDHYLEVPFDLSEVFFITTANNLYTIPPALLDRMEVIRVPGYTEEEKLHIAKDFILPKLYEQSGLNPEEVSFSDQAIIRIIREYTREAGVRNLERNLLSILRKLAVEKLEKGFSRVRITVKNVEDYLGVPKFRYGKALEKPEIGVVAGLAWTEFGGETMLIECQVVKGKGQLILTGSLGQTLKESAMAALTYVRSRAKQLGIDEEFYKKYDIHVHAPEGAIPKDGPSAGITIATAMISALKKEPVPNDLAMTGEITITGKVLPIGGVKEKVLAAHRIGLDRVILPKDNKINMEEIGDEVKKKLRFYFVDTMDQVVEIVFGKTS

lon

Lon protease

768 amino acids

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Belongs to the peptidase S16 family.

86.349 kDa

MLKAPFLPIRDLVIFPNVVTPIYVGRANSIATLEKAIANKTKLVLGLQKDASQENPTFDGDIYEVGVIANIVQIIRMPNNNIKVLVEAEDRVKIKNIEKEENEYVTTYTVIKETLKDSKETEAIYRKVFTRFEKYVSMIGKFSSELILNLKKIEDYSNGLDIMASNLNISSEKKQEILEISNVRDRGYRILDEIVAEMEIASLEKTIDDKVKNKMNEAQRAYYLKEKISVMKEELGDFSQDDDVIEIVDRLKNTELPKEVREKLEAEVKKLTKMQPFSAESSVIRNYIEAVLELPWNSETNDVLDLKKASQILERDHYGLKDAKEKVLDYLAVKKLNPSMNGVILCLSGPPGIGKTSLVKSIAESMGRKFVRVSLGGVRDEAEIRGHRRTYVGSMPGKIMKAMKEAGTNNPVMLLDEIDKMSNDFKGDPASAMLEVLDPEQNKNFEDHYIDMPFDLSKVFFVATANDLRNVSAPLRDRMDILQLSSYTEFEKLHIAQKFLLKQAQKENGLANIDIKIPDKVMFKLIDEYTREAGVRNLKREIITICRKLAREVVEKDTKKFNLKPTDLEKYLGKAKFRPEKSRKATGKIGVVNGLAWTAVGGVTLDVQGVDTPGKGEVTLTGTLGNVMKESASVAMTYVKANLKKYPPKDKDFFKDRTIHLHFPEGATPKDGPSAGITITTAIVSVLTNKKVRQDIAMTGEITITGDVLAIGGVREKVIGAHRAGIKEVILPEDNRVDTDEIPDELKSTMKIHFAKTYDDVSKLVFVK

lon

Archaeal Lon protease

635 amino acids

Serine protease that displays ATP-independent proteolytic activity towards peptides and unfolded proteins and ATP-dependent activity for the cleavage of folded proteins.

Belongs to the peptidase S16 family. Archaeal LonB subfamily.

70.258 kDa

MDEESTKERLIPREYGESLDLGIDFKTTEEIPVPEKLIDQVIGQEHAVEVIKTAANQRRHVLLIGEPGTGKSMLGQAMAELLPTENLEDILVFPNPEDENMPKIKTVPACQGRRIVENYRRKAKEQEGIKNYLLMFVIFTVILAIIMEPTATTLLMGMFVVLLSMMVLSNMRFRNTVLVPKLLVDNCGRKKAPFVDATGAHAGALLGDVRHDPFQSGGLGTPAHERVEPGMIHRAHKGVLFIDEIATLSLKMQQSLLTAMQEKKFPITGQSEMSSGAMVRTEPVPCDFILVAAGNLDTIDKMHPALRSRIRGYGYEVYMRTTMPDTIENRRKLVQFVAQEVKRDGKIPHFTREAVEEIVREAQKRAGRKGHLTLRLRDLGGIVRAAGDIAIKKGKKYVEREDVLEAMRMAKPLEKQLADWYIENKKEYQVIKTEGGEIGRVNGLAVIGEQSGIVLPIEAVVAPAASKEEGKIIVTGKLGEIAKEAVQNVSAIIKRYKGEDISRYDIHVQFLQTYEGVEGDSASISVATAVISALENIPIRQDVAMTGSLSVRGEVLPIGGATPKIEAAIEAGIKKVIIPKANEKDVFLSPDKAEKIEIYPVETIDQVLEIALQDGPEKDELLRRIREALPLYGSS