Protein
Modification methylase LlaDCHIA
Organism
Lactococcus lactis subsp. cremoris
Function
This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the LlaDCHI endonuclease.
Similarity
Belongs to the N(4)/N(6)-methyltransferase family.
Sequence
MNLLQKNKINLRPFTKWTGGKRQLLPHIQYLMPEKYNHFFEPFIGGGALFFELAPQKAVINDFNSELINCYRQMKDNPEQLIELLTNHQRENSKEYYLDLRSSDRDGRIDKMSEVERAARIMYMLRVDFNGLYRVNSKNQFNVPYGRYKNPKIVDKELIESISEYLNNNSIKIMSGDFEKAVKEAQDGDFVYFDPPYIPLSETSAFTSYTHEGFSYEDQVRLRDCFKQLDSKGVFVMLSNSSSPLAEELYKDFNIHKIEATRTNGAKSSSRGKITEIIVTNYGN