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lctA

Gene
lctA
Protein
Lantibiotic lacticin-481
Organism
Lactococcus lactis subsp. lactis
Length
51 amino acids
Function
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. Lacticin 481 is a broad spectrum bacteriocin exhibiting activity against a wide range of lactic acid bacteria and C.tyrobutyricum.
Similarity
Belongs to the type A lantibiotic family.
Mass
5.677 kDa
Sequence
MKEQNSFNLLQEVTESELDLILGAKGGSGVIHTISHECNMNSWQFVFTCCS