Protein
GPI ethanolamine phosphate transferase 1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
Similarity
Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
Sequence
MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKNITYTIHEKVN