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ispF

Gene
ISPF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Plasmodium falciparum (isolate 3D7)
Length
240 amino acids
Function
Converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP.
Similarity
Belongs to the IspF family.
Mass
27.161 kDa
Sequence
MFLKGYTSNVVLIILTFFILLTKEEKNIKNNISGYCFLNFGLKKNAIIKKREKQNLKLFCYNGIRIGQGYDIHKIKVLDEEYNTYANNDFNKNEQSFKTLTLGGVKINNVLVLSHSDGDIIYHSIVDSILGALGSLDIGTLFPDKDEKNKNKNSAIFLRYARLLIYKKNYDIGNVDINVIAQVPKISNIRKNIIKNISTVLNIDESQISVKGKTHEKLGVIGEKKAIECFANILLIPKNS

Gene
ISPF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Plasmodium falciparum (isolate HB3)
Length
240 amino acids
Function
Converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP.
Similarity
Belongs to the IspF family.
Mass
27.161 kDa
Sequence
MFLKGYTSNVVLIILTFFILLTKEEKNIKNNISGYCFLNFGLKKNAIIKKREKQNLKLFCYNGIRIGQGYDIHKIKVLDEEYNTYANNDFNKNEQSFKTLTLGGVKINNVLVLSHSDGDIIYHSIVDSILGALGSLDIGTLFPDKDEKNKNKNSAIFLRYARLLIYKKNYDIGNVDINVIAQVPKISNIRKNIIKNISTVLNIDESQISVKGKTHEKLGVIGEKKAIECFANILLIPKNS

Gene
ISPF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic
Organism
Catharanthus roseus
Length
236 amino acids
Function
Converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP. Also converts 4-diphosphocytidyl-2C-methyl-D-erythritol into 2C-methyl-D-erythritol 3,4-cyclophosphate and CMP.
Similarity
Belongs to the IspF family.
Mass
25.364 kDa
Sequence
MAMATSFYCSTAIPSKKTNQNRENFLCSPVGGSKTTPSYIRLSTRQSRTLSLVVSAAASGAAVEAEPKFAAVTPSKILSFRVGHGFDLHRLEPGYPLIIGGINIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDTDPKWKGAPSSVFIKEAVRLMDEAGYELGNLDATLILQRPKVSPHKEAIRQNLCQLLGADPCVVNLKAKTHEKVDSLGENRSIAAHTVVLLMRK

Gene
ISPF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic
Organism
Arabidopsis thaliana
Length
231 amino acids
Function
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP. Also converts 4-diphosphocytidyl-2C-methyl-D-erythritol into 2C-methyl-D-erythritol 3,4-cyclophosphate and CMP. Is essential for chloroplast development.
Similarity
Belongs to the IspF family.
Mass
24.812 kDa
Sequence
MATSSTQLLLSSSSLFHSQITKKPFLLPATKIGVWRPKKSLSLSCRPSASVSAASSAVDVNESVTSEKPTKTLPFRIGHGFDLHRLEPGYPLIIGGIVIPHDRGCEAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPKWKGAASSVFIKEAVRLMDEAGYEIGNLDATLILQRPKISPHKETIRSNLSKLLGADPSVVNLKAKTHEKVDSLGENRSIAAHTVILLMKK

Gene
ISPF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic
Organism
Oryza sativa subsp. japonica
Length
222 amino acids
Function
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP (Probable). Also converts 4-diphosphocytidyl-2C-methyl-D-erythritol into 2C-methyl-D-erythritol 3,4-cyclophosphate and CMP (Probable). Is essential for chloroplast development (PubMed:29143298).
Similarity
Belongs to the IspF family.
Mass
23.524 kDa
Sequence
MATASSLFLASPVATAPTARARSTPSASPARPSLRLRRPSTLAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEPGLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSSVFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADPSVVNLKAKTHEKVDSLGENRSIAAHTVVLLMRK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Anaplasma marginale (strain St. Maries)
Length
184 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.574 kDa
Sequence
MITAVRAVPFRVGIGYDVHGFADSPPENGHIVLCGVEIAFHRKIKAHSDGDVGTHALVDALLGCVGEGSIGEHFPNTDPRWENMSSTHFLLEAQSKALAKGYAVLNFDLTIVCELPKIIPHVPKMKLFMSKLLGMDASAINIKAVTTEKLGFIGRGEGIAAHAVVLCRKVTAAAPNPGSENPRG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Verminephrobacter eiseniae (strain EF01-2)
Length
183 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.605 kDa
Sequence
MNLRIGEGWDVHALVPGRRLVIGGVELEHPMGLGLLGHSDADVLLHAITDALLGAAALGDIGRHFPDTDAAFRAADSRLLLAEAARRVRAAGYEIGNIDSTVVAQAPRLAAHIPAMRLAIARALGVDQGQVNVKAKTAEGLGPVGQNLAIEARAVALICATPGAGAIGPAAQRVSSAWSGSGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Eubacterium eligens (strain ATCC 27750 / VPI C15-48)
Length
183 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.786 kDa
Sequence
MRVGMGYDVHKLVKDRKLIMGGVEIPYELGLLGHSDADVLLHAIMDALLGAAALGDIGKHFPDTDDRYKGISSIKLLEEVGKKIDEANYIIENIDATIIAQKPKMRPYIDDMRKNIADALKIDVDRVNVKATTEEGLGFTGSGEGISSQAICSLNSVSNYIYGAADMTNCRSDCGGCMGCQNK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13)
Length
178 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.418 kDa
Sequence
MTEIPSSFVLPDPEWIYRVGIGQDSHRFLPDEDPKPCILGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHKGILGGLADELLKTKGITDSVVYLQEAVASLKPTQQVSHLAITIEGKRPKLLPQLPSMRKRIAEVLHIPLDSINITATSGEGLTAMGQGYGVQCFCVLTIMEYCRY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Length
178 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.46 kDa
Sequence
MTEIPSSFVLPDPEWIYRVGIGQDSHRFLPDEDPKPCILGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHKGILGGLADELLKTKGITDSVVYLQEAIASLKPTQRVSHLAITIEGKRPKLLPQLPSMRKRIAEVLHIPLDSINITATSGEGLTAMGQGYGVQCFCVLTIMEYCRY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Length
178 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.446 kDa
Sequence
MTEIPSSFVLPDPEWIYRVGIGQDSHRFLPDEDPKPCILGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHKGILGGLADELLKTKGITDSVVYLQEAVASLKPTQRVSHLAITIEGKRPKLLPQLPSMRKRIAEVLHIPLDSINITATSGEGLTAMGQGYGVQCFCVLTIMEYCRY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Length
178 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.185 kDa
Sequence
MSEPSSCFVLPDPEWIYRVGIGQDSHRFLPSDNPKPCVLGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHQVILGALADELLKAKGISDSAVYLKEAVASLKPTQKISHLAITIEGQRPKLLPKISAMREKIAEILRISLDSVNITATSGEGLTSMGQGHGVQCFCVLTVMEFCPR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Length
178 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.446 kDa
Sequence
MTEIPSSFVLPDPEWIYRVGIGQDSHRFLPDEDPKPCILGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHKGILGGLADELLKTKGITDSVVYLQEAVASLKPTQRVSHLAITIEGKRPKLLPQLPSMRKRIAEVLHIPLDSINITATSGEGLTAMGQGYGVQCFCVLTIMEYCRY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990)
Length
177 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.858 kDa
Sequence
MRVGMGYDVHKLVEGRDLILGGVKVPHTLGLLGHSDADVLLHAIMDALLGAAALGDIGKHFPDTDPAYEGISSLKLLEHVRDLIAKKGYVIENIDATVIAQKPKLRPYIEQMEQNVADTLQIAKEQVNIKATTEEWLGFTGREEGIASQAICSLTGLYEASMQVGGGCSGCGGCQAD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Length
177 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.079 kDa
Sequence
MFFAEIKQEEVIVGGFRIGQGFDVHQLVEGRKLVIGGVTIPYEKGLLGHSDADVLLHAICDAVLGAAALGDIGRHFSDTDPRYRNIDSRVLLQNVGNLLAERGYRVVNVDATIIAQAPRMASHIPAMVANIAQDLRMQPGDVNVKAKTAERLGPVGRGEGIEAEAVCLITHMNQTTD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xylella fastidiosa (strain 9a5c)
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.764 kDa
Sequence
MSGLFRGRVMTGLNVRIGQGYDVHAFGPGDHVMLGGVRVPHRCGVLAHSDGDVILHALCDAMLGALGLGDIGQHFPPSDVRWKGADSGVFVRHCHLLLRERDWCVGNVDATAICESPKIAPYVNAMREGIARLLEVQPECVSVKATTSEGLGFIGRGEGLAAQVVVLLYRLNGVVV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.771 kDa
Sequence
MSGLFRGRVMTGLNVRIGQGYDVHAFGPSDHVMLGGVRVPHRCGVLAHSDGDVILHALCDAMLGALGLGDIGQHFPPSDVRWKGADSGVFVRHCNLLLRERDWCVGNVDATAICESPKIAPYVNAMREGIARLLEVQPECVSVKATTSEGLGFIGRGEGLAAQVVVLLYRLNGVVV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia abortus (strain DSM 27085 / S26/3)
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.776 kDa
Sequence
MNAENDSSLPKPQWIYRVGIGQDSHRFLSESSAKPCILAGVIFENSPGFQANSDGDIIFHAICNAISSVTHRIILGEVADELLHTRGITDSSVYLSEAIKSLKSNQMISHAAITIEGNRPKFLPKLSAMRQSIASALNIPLGSVGITATSGEGLSDFGCGDGVQCFCILTIMEYCG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydophila caviae (strain GPIC)
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.804 kDa
Sequence
MDAENDSPLPKPQWIYRVGIGQDSHRFLSESSAKPCILAGVIFENSPGFQANSDGDIVFHAICNAISSVTHRIILGEVADELFHTRGITDSSVYLSEAIKSLKSNQMISHVAITIEGNRPKFLPKLSAMRQSIASALNIPLGSVGITATSGEGLSDFGCGDGVQCFCVLTVAEYCN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia felis (strain Fe/C-56)
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.788 kDa
Sequence
MNAEKDSPLPKPQWVYRVGIGQDSHRFLSESSAKPCILAGVIFENSPGFQANSDGDIVFHAICNAISSVTHRIILGDVADELFHTRGITDSSIYLSEAIKSLKPNQLISHVAITIEGNRPKFLPKLSAMRQSIASALNISLGSVGITATSGEGLSDFGCGDGVQCFCVLTVMEYCG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlamydia pneumoniae
Length
176 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.131 kDa
Sequence
MDRDNEVPLPKPKWIYRTGIGQDSHRFLPESSTKPCILGGIIFDHCPGFQANSDGDIIFHAICNAISSVTNKIILGKVADELLQTRGITDSGIYLEEALKSLKPNQKISHVAITIEGSRPKFLCKLSALRQNIAQVMNLTPTDIGITATSGEGLSDFGCGDGVQCFCVLTVMEYCD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bifidobacterium longum (strain NCC 2705)
Length
174 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.434 kDa
Sequence
MGSVGVLIGQGFDAHRFAPAGSGRELWIAGLYWPVPDSCSEADAAKYEGIEGDSDGDVAAHALIDALLAAARLGDIGSLFGVGADAHGAGMHGIDMLQEVVAHLASNGYTPASASVAIIGNRPKIGTRRAEAEAALSAAVGCPVSVTATTTDHMGFTGHGEGIAAIANALVEKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Length
174 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.462 kDa
Sequence
MGAAGVLIGQGFDAHRFAPAGSGRELWIAGLYWPVPDSCSEADAARYEGIEGDSDGDVAAHALIDALLAAARLGDIGSLFGVGADAHGAGRHGIDMLQEVVAHLASNGYTPASASVAIIGNRPKIGTRRAEAEAALSAAVGCPVSVTATTTDHMGFTGRGEGIAAIANALVEKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bifidobacterium longum (strain NCC 2705)
Length
174 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.434 kDa
Sequence
MGSVGVLIGQGFDAHRFAPAGSGRELWIAGLYWPVPDSCSEADAAKYEGIEGDSDGDVAAHALIDALLAAARLGDIGSLFGVGADAHGAGMHGIDMLQEVVAHLASNGYTPASASVAIIGNRPKIGTRRAEAEAALSAAVGCPVSVTATTTDHMGFTGHGEGIAAIANALVEKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Length
174 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.462 kDa
Sequence
MGAAGVLIGQGFDAHRFAPAGSGRELWIAGLYWPVPDSCSEADAARYEGIEGDSDGDVAAHALIDALLAAARLGDIGSLFGVGADAHGAGRHGIDMLQEVVAHLASNGYTPASASVAIIGNRPKIGTRRAEAEAALSAAVGCPVSVTATTTDHMGFTGRGEGIAAIANALVEKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Length
174 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.5 kDa
Sequence
MASEASDVRLPPGGPVVLPLVGIGTDIHAFEDGRELWCAGLKWEGEGPGLAGHSDADVVAHAACNALFSAAGLGDLGQHFGTGRPEWSGASGVTLLTEAARIVRAAGFTIGNVAVQVVGPRPKIGKRRDEAQKILSDAVGAPVSVSGATTDGLGFPGRDEGLMAVATALVVRAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ehrlichia canis (strain Jake)
Length
173 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.16 kDa
Sequence
MKQHINKPTFKVGIGYDVHKFDNIEYDATNTFITICGIKINHHKKIVAHSDGDVGLHALTDAILGAVGCGSIGQHFPNTDNKWKDAKSDYFLIEAKNKAQEKGYYISNADIIIICEQPKIMPHALKMQEYIANLIKIDTSCINVKATTTEKLGFLGRKEGIAAQAIVLCCLQN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Length
173 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.069 kDa
Sequence
MNQHPNKPIFKVGIGYDVHKFDNTCYNDANTFITICGIKINYHKKIIAHSDGDVGLHALTDAILGAVGCGSIGQHFPNTDNTWKNIKSDYFLIEAQKKAQEKGYSISNADITIICEQPKIMPHALEMQEYIANLICIDPSCINVKATTTEKLGFLGRKEGIAAQAIVLCCLQN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ehrlichia ruminantium (strain Gardel)
Length
173 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.088 kDa
Sequence
MSKHTNIPMFRIGIGYDVHRFDNINNDDSNTSITICGIEINYHKKIIAHSDGDVGLHALADAILGAVGCGSIGQHFPNTDQKWKNAKSSHFVIEAQKKAQERGYIISNADIIIICEQPKIMPYALEMQHYIAQFTSIDPSFINIKATTTEKLGAIGRNEGIAAQAIVLCSQQY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ehrlichia ruminantium (strain Welgevonden)
Length
173 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
19.088 kDa
Sequence
MSKHTNIPMFRIGIGYDVHRFDNINNDDSNTSITICGIKINYHKKIIAHSDGDVGLHALADAILGAVGCGSIGQHFPNTDKKWKNAESSHFVIEAQKKAQERGYIISNADIIIICEQPKIMPYALEMQHYIAQFTSIDPSFINIKATTTEKLGAIGRNEGIAAQAIVLCSQQY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Length
172 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.225 kDa
Sequence
MVSETPGAGSPAAPVIPLVGIGTDIHAFEEGRKLWCAGLKWEGEGPGLAGHSDADVVAHAACNALFSAAGLGDLGQHFGTGRPEWSGAAGITLLTEAARIVRAGGFEIGNVAVQVVGSRPKIGKRREEAQKVLSEAVGAPVSLSAATSDGLGFTGRGEGIAGLATALVYRTA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Length
171 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.077 kDa
Sequence
MRQNRRFLRCQVTEQIIPRVGIASDAHQIEAGKPCWIACLLFDGVDGCEGHSDGDVVAHAIVDALLSASGLGDLGSFVGVGRPEYDGVSGTQLLIEVRELLITRGFTIGNVAAQLVGQTPKFGPRREEAQQVISDILGAPCFLSATTTDHMGFTGRGEGRAALATAVVWTG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Length
171 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.369 kDa
Sequence
MRIGHGYDVHKLVSGRKLILGGVDIPYERGLLGHSDADVLLHAISDAILGAIGEGDIGKHFPDTDPAYKGADSIKLLMHVMGLARDRGYAIGNVDATIVAQRPKLAAHIPLMGENIAKALETEASRINVKATTTEELGFCGRGEGIAAYAVALLQRRHELSPETREVLETR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
Length
170 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.295 kDa
Sequence
MRIGHGFDVHKFGGKGPLVLGGVKIPFELGFIAHSDGDVAIHALCDAILGALCLADIGNHFPDTDGQYENISSRILLRHVVSLMTDKGFQLGNADITIVAQAPKMAPHLVAMRTCLSEDLKTTIEQVNVKATTTEKLGYTGRKEGISVHAVVLLIAIEHPLPLIEEIQNI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
170 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.969 kDa
Sequence
MGSESSGTAELPPLPQVGIGTDIHAFEDGRELWCAGLKWEGEGTGLAGHSDADVVAHAACNALFSAAGAGDLGQHFGTGRPEWSGASGVTLLAEAARIVRARGFRIGNVAVQVVGARPKIGKRRDEAEAVLSAAVGAPVSVSGATTDGLGFPGRGEGLMAVATALVVRGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Akkermansia muciniphila (strain ATCC BAA-835 / Muc)
Length
169 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.689 kDa
Sequence
MKNMIALTGIGYDIHRFAEVPRPLMLGGVHIPSSRGLDGHSDADVLCHAIADALLGAAGLPDIGYWFPPGDPSCKDIPSLDIVAKAVSLIRERGGRIVNVDSSLIAESPRISPYLEQMKGALGAALGISPVRVGIKATTNEQLGALGRREGIAAFAVAAILMPEDLTMP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
169 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.836 kDa
Sequence
MMPFDIRVGQGYDVHALVPGRKLILGGVEIPHDRGLLGHSDADALLHAVTDALFGAAALGDIGRHFPDTDAQFAGADSRVLLREAARRVREAGYEIGNVDATVIAQAPKLAPHIGAMVANLAEDLGIARGRCNVKAKTNEKLGFEGRQEGIVAQAAVLLWRASVGDAQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cupriavidus necator (strain JMP 134 / LMG 1197)
Length
169 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.882 kDa
Sequence
MMPFDIRVGQGYDVHALVPGRKLILGGVHIPHDRGLLGHSDADALLHAITDALFGAAGLGDIGRHFPDTDAQFAGADSRVLLREAARRVREAGYEIGNVDASVIAQQPKLAPHIPGMVANIADDLGLPATRCNVKAKTNEKLGFEGRQEGIVAQAAVLIWRGAIADAQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)
Length
169 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.836 kDa
Sequence
MMPFDIRVGQGYDVHALVPGRKLILGGVEIPHDRGLLGHSDADALLHAVTDALFGAAALGDIGRHFPDTDAQFAGADSRALLREAARRVREAGYEIGNVDATVIAQAPKLAPHIGAMVANLAEDLAIARGRCNVKAKTNEKLGFEGRQEGIVAQAAVLLWRASVADAQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.749 kDa
Sequence
MIMIKIGQGIDVHAFHNNGQQQQYVVLAGVPIEHTHSLLAHSDGDVVLHALADALLGALALGDIGQHFPDTDAANAGLDSRVLLRYVYGKVLAAGYMLGNADITVMCERPKLAVHNLAMRANIASDLQTDVSNISVKATTTEKLGFTGRQEGIMANAVVLLVPNTSGV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Psychrobacter cryohalolentis (strain K5)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.685 kDa
Sequence
MIMIKIGQGIDVHAFHNNGQQQQYVVLAGVPIDHTHSLLAHSDGDVVLHALADALLGALALGDIGQHFPDTDAANAGLDSRVLLRYVYGKVLAAGYILGNADITVMCERPKLAPHNLAMRANIASDLQTDVSNISVKATTTEKLGFTGRQEGIMANAVVLLVPNASGV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ralstonia pickettii (strain 12J)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.86 kDa
Sequence
MNWMDIRIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHFPDTDPAFAGADSRVLLREAVRRVHKAGYAVGNVDATVIAQKPKLAPHVPGMVANLAEDLGIAPERCNVKAKTNEKLGFEGKEEGIVAQAVVLIYRAEAAEQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.78 kDa
Sequence
MNWMDIRIGQGYDVHALVEGRKLILGGVEIPHTRGLLGHSDADALLHAITDALFGAAGLGDIGRHFPDTDPAFAGADSRVLLREAVRRVREAGYDVGNVDATVIAQKPKLAPHVPGMVANLAADLGIAPGRCNVKAKTNEKLGFEGREDGIVAQAAVLIYRAEAAEQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Anaplasma phagocytophilum (strain HZ)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.387 kDa
Sequence
MGYLGMPFRVGMGFDVHRFTESREEGQYIPICGIKVAHTQGIVAHSDGDVALHALTDALLGCMGEGSIGQHFPNSDPQWKNASSSYFLLEAQKKAAAKSYAILNFDVTIVCEQPKIMPHVPKMKEFLSKLLDVDVSQMNIKAVTTEKLGFLGRGEGIAAHAVLMCYRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.908 kDa
Sequence
MNPFDIRIGQGYDVHALVPGRKLILGGVDIPHDRGLLGHSDADALLHAVTDALFGAAALGDIGRHFPDTDPNFAGADSRVLLREAVRRVREAGYEIGNVDATVIAQKPKLAPHISGMVANLAEDLGLPVTRCNVKAKTNEKLGFEGKEEGIVAQAAVLIYRRNGDAQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cutibacterium acnes (strain DSM 16379 / KPA171202)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.829 kDa
Sequence
MIEIRTGIGTDVHQLSAGVPMHVAGLSFPDETVGLVGHSDGDVACHAICDALLSATGLGDIGSIFGTADPQWAGAAGVALLGHVVALVTGEGWTIQNVAVQVVGQRPRMAARRAEAEAALAQTVGAPVSVSATTTDHLGFTGRGEGVAAIASALVTRGLKGEDSSLIR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Desulfococcus oleovorans (strain DSM 6200 / Hxd3)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.296 kDa
Sequence
MRIGTGYDLHRLVKGRRLVLGGVALPFEKGLDGHSDADVLVHAVCDALLGAAGLGDIGDHFPDTDARFKGVSSLLLLTETGRMLKEKGFFVVNIDATVLAQAPKLGAHKAAMAANMATALGIDAACVNVKATTTEGLDAVGRGEAMAAMSVALIIEEEARDSRGQGAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neorickettsia sennetsu (strain ATCC VR-367 / Miyayama)
Length
168 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.479 kDa
Sequence
MYRVGFGYDVHKIDKPVKTGNTCIVLCGVSVPCEYKVIAHSDGDVALHALVDALLGAACIEGANDIGMLFPDTDEKWRGKSSSYFVEHVVTLIQRAGYVVNNADLTIVCETPRIQQYKSEMQQQVADLLCVRKEQINVKATTTEKLGFEGRKEGIAAYAIVSLTKIRP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus parasuis serovar 5 (strain SH0165)
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.981 kDa
Sequence
MIRIGHGFDVHAFGQDRPLMICGVAVPYHTGFIAHSDGDVALHALSDALIGAAALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVQATGYVVGNVDVTIIAQAPKMRPYIDQMRQVIADDLNCDISCVNVKATTTEKLGFTGRGEGIACEAVALLIKPALCSSYRNI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus parasuis serovar 5 (strain SH0165)
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.981 kDa
Sequence
MIRIGHGFDVHAFGQDRPLMICGVAVPYHTGFIAHSDGDVALHALSDALIGAAALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVQATGYVVGNVDVTIIAQAPKMRPYIDQMRQVIADDLNCDISCVNVKATTTEKLGFTGRGEGIACEAVALLIKPALCSSYRNI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Azobacteroides pseudotrichonymphae genomovar. CFP2
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.447 kDa
Sequence
MKIRIGFGYDVHPLVMNYNLWLGGIKIPYEKGLKGHSDADVLIHALCDALLGAADIGNIGTNFPNTNKKLRNIDSKILLKQTMSFIYSKNYELNNADITVCIEQPKLNPFIPQMKTCLAEIMQTDKGNISIKATTSEKMGFIGREEGIAVFATVLITPINEIGISCQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nitrosomonas eutropha (strain DSM 101675 / C91)
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.571 kDa
Sequence
MKKIRIGQGFDIHQLAAGRELVIGGVTIPYEKGLLGHSDADVLLHALCDALLGAAALGDIGKHFSDTDARYKDIDSRKLVCKVHRLLAETGYRVVNIDATIIAQAPKMAPHISGMIANIAQDLAMPAGNINIKAKTAEKLGAVGRGEGIVAEVVCLIANSDEGEAQP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.707 kDa
Sequence
MRIGYGFDIHAFGSIKPLIIGGVQIPYNKGLIAHSNGDLLIHSLIDALLGATAMGDIGTFFPSEDKKYKNINSRILLKYIWKRIYLKNYRISNIDITIITETPKILSYIFLMRSNIASDLNIKIEKISVKSTSSKMIGCIGRKEGIACQSLVMLVKSKNTDRKNNII

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Prochlorococcus marinus (strain MIT 9312)
Length
167 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.528 kDa
Sequence
MNDFTPKFRIGNGYDIHRLVTGRKLIIGGVNLKHPDNLGLDGHSDADVLTHSIMDALLGALSLGDIGKYFPPSDDKWKDVDSLILLSKVIDLVRKQGWEINNIDSVLVAERPKIKPFVEIMKKNLSNTLKIDNSFIGIKATTNEKLGPEGREEGISCHSVVLLEKKE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.751 kDa
Sequence
MMTQPQPLAFRIGLGYDSHRLGPDGPLRIGGLDVAGDFHAIGHSDADVLLHAVTDALMGAIAGPDIGRLFPDDADENRGRDSRDFVEEALRRVNEAGYEINNVDAVILAQKPKMAPHIDSMRAAVAEMLQTTIEQVGLKAKTGEGVDAVGRSEAIAARAVVMLSRR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.645 kDa
Sequence
MSFNFRIGQGYDVHAFGPGDHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDARWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIADLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAAPHQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.575 kDa
Sequence
MSFNFRIGQGYDVHAFGPGDHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGQHFPPSDARWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIAGLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRTAVPHQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.211 kDa
Sequence
MSLLLRVGIGYDSHRFGEGGPMRLGGIDIPSDRHCAGHSDGDAICHAVTDALLGAAGLGDIGEMFPDTDAANKGKDSVVMLEAAVSRLHAAGWRVGNVDITVITQQPKIGPHRAAMRDRLATVLGVNSTEVFVKGKTNEGLGWIGREEGLGVIATATILAIGSSTL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechococcus sp. (strain CC9311)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.484 kDa
Sequence
MTSSVPSLRIGNGYDVHRLVPDRPLILGGQLLEHPAGLGLDGHSDADVLVHAIMDALLGALSLGDIGKYFPPSDPQWKGADSLVLLEQVVALVKARGWGVVNVDAVLIAERPKLKPHIEAMRSAIALRIGVAPDQVGVKATTNEQLGPEGREEGISCQAVALLQAL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Prochlorococcus marinus (strain MIT 9215)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
18.426 kDa
Sequence
MTSKSPKFRIGNGYDIHRLEIGRKLIIGGVKLNHPDNLGLDGHSDADVLSHSIMDALLGALSLGDIGKYFPPSDEKWKDVDSLILLSKVIDLVRKQGWEINNIDSVIVAERPKIKPYVEIMKRNLSKTLKIDDSFIGIKATTNEKLGPEGREEGISCHSVVLLEKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6)
Length
166 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.849 kDa
Sequence
MIIPRTGIGVDVHAFAAEGEARQLWVGGLLWPGERGLAGHSDGDPVAHAAADALFSAAGIGDLGTHFGTDRPEFAGASGVTLLAEAARIVRAAGFEIGNIAVQFVANRPKFGPRREESQQVLSDAAGAPVSVTATTSDGLGFTGRGEGISAVATALVYPRLSESIG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.652 kDa
Sequence
MIRIGHGFDVHKFGGVGPLTIGGEKIDYPQGFLAHSDGDVAIHALCDAILGALAMGDIGKHFPDTASEYENIDSRILLRHVVSLAKEQGYVLGNGDVTIVAQAPKMLPHIQAMRSNLASDLNCELSQINVKATTTEKLGFEGRKEGISSHAVVIMNKESMSKTNA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.837 kDa
Sequence
MTMSIRIGNGYDIHRLVSDRALILGGVHIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGHYFPPTDPQWAGADSLVLLNQVNELIRAQGWRIGNIDSVVVAERPKLKPHIKTMRDKLANVLQLEPNQIGVKATTNEKLGPVGREEGICAYAVVLLVSSDPVN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.923 kDa
Sequence
MNGLPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLRDPLGSQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.918 kDa
Sequence
MRIGIGFDVHPLKKGETLILGGVHIQGEYGLAGHSDADVLTHALMDAILGAMGEADIGYHFPDTDPSYRGISSLKLLKKVYNMMKPRGFSIGNIDLIIMAQSPKLSPYYNKIKENYTRILQLDSSRINIKATTTENLGFVGREEGIAAQAAVLLIDTKEGDINAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.918 kDa
Sequence
MRIGIGFDVHPLKKGETLILGGVHIQGEYGLAGHSDADVLTHALMDAILGAMGEADIGYHFPDTDPSYRGISSLKLLKKVYNMMKPRGFSIGNIDLIIMAQSPKLSPYYNKIKENYTRILQLDSSRINIKATTTENLGFVGREEGIAAQAAVLLIDTKEGDINAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Aromatoleum aromaticum (strain EbN1)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.909 kDa
Sequence
MKAPFRIGQGFDVHALVPGRALIVGGVHIPFERGLLGHSDADVLLHALTDALLGAAGLGDIGRLFPDTDAAHAGADSRVLLREAFAAVRAAGFGVVNVDATVICRAPRILPHAPAMVANIAADLGIDAAAVNIKGKTTEKLGFTGRGEGIAAQVVALLMRHGDET

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.738 kDa
Sequence
MGGYRVGLGVDVHAFADPAEGRQLVLGGVRIPSERGLRGHSDADVLAHAVTDALLGAAGLEDIGHYFPDTDERFRDADSIWLLREARRIVGGGWEVVNVDAVVICERPRIREHREKMRENLAAALGVEASRVSVRGTTSERLGFTGRGEGIAAQAVCLLERAVGT

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.833 kDa
Sequence
MESDPMFIGFGYDRHPLVEGRRLVLAGVEIDAPLGSLGHSDGDVLSHAIIDALLGAGCLGDIGTWFPETKEYKDANSLDLLKETVKILEERGFSVVNVDATVVASIVKLSPYREKIVENLKSALETSRVNVKFKSGNTLGFEGEERGISAYAVCLVEEKGCTKST

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.92 kDa
Sequence
MESDSMFIGFGYDRHPLVEGRRLVLAGVEIDAPLGSLGHSDGDVLSHAIIDALLGAGCLGDIGTWFPETKEYKDANSLDLLKETVKILEERGFSVVNVDATVVASIVKLSPYREKILENLKSALETSRVNVKFKSGNTLGFEGEERGISAYAVCLVEEKKCTKSI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.874 kDa
Sequence
MTMSIRIGNGYDIHRLVSDRALILGGVHIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGHYFPPTDPQWAGADSLVLLSQVNELIRTQGWRIGNIDSVVVAERPKLKPHIKTMRDKLADILQLEPNQIGVKATTNEKLGPVGREEGICAYAVVLLVSSDEIS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.621 kDa
Sequence
MRIGHGFDVHKFGGEGPLVIGGVRIPYTQGLLAHSDGDVVLHAVTDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAWRRINDKGYQLGNLDVTIIAQAPKMAPHIPQMRVNLAEDLQCHMDDVNVKATTTEQLGFTGRGEGIACEAVALLVKKETGEIVAW

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Length
165 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.548 kDa
Sequence
MRIGHGFDVHKFGGEGPLVIGGVRIPYTQGLLAHSDGDVVLHAVTDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAWRRINEKGYQLGNLDVTIIAQAPKMAPHIPQMRVNLAEDLLCHMDDVNVKATTTEQLGFTGRGEGIACEAVALLVKKGTGEIVAW

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium kluyveri (strain NBRC 12016)
Length
164 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.766 kDa
Sequence
MRVGLGYDVHKLGYNTPLILGGVNIPFNKGLIGHSDADVLVHAIMDALLGALSLGDIGKHFPPSDMKYKNISSLKLLNYVSNLIKSKGYSIGNIDSTIIAEEPKLFPYIPDMRLNIAKILKVNTSIISVKATTEEGLGFTGKKEGIAAQSICLLYNNLKHSIDL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
Length
164 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.766 kDa
Sequence
MRVGLGYDVHKLGYNTPLILGGVNIPFNKGLIGHSDADVLVHAIMDALLGALSLGDIGKHFPPSDMKYKNISSLKLLNYVSNLIKSKGYSIGNIDSTIIAEEPKLFPYIPDMRLNIAKILKVNTSIISVKATTEEGLGFTGKKEGIAAQSICLLYNNLKHSIDL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Length
164 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.307 kDa
Sequence
MIRVGQGFDAHRFGEPGTPLILGGVQVPHERGLAAHSDGDVLMHAVTDGLLGAAGEGDLGTHFPDSDDAYKGIDSRILLRDALQRVRAGGWRVVNVDATLIAQAPRMNPHVGAMRDHLAADLEVAPSAVNVKATTTERMGFPGRGEGIAAMAVVLIARDGFFEH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nocardioides sp. (strain ATCC BAA-499 / JS614)
Length
164 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.318 kDa
Sequence
MDLLPRVGIGTDVHRLVDGVPLHLAGLHWPDEPQGLEGHSDADVAAHAACDALFSAAGLGDLGSNFGTADPAWAGASGAALLEETARRVRAAGFEIGNVAVQVIGNRPRLGGRRAEAETALSAAVGAPVSVSATTADGLGLTGRGEGVAAIATALVTPRHHGSA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Length
164 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.623 kDa
Sequence
MMRIGHGYDVHQLVAERKLILGGVDIPHTLGLLGHSDADVLLHAICDAILGALGEGDIGKHFPDTDPAYKGISSIKLLHEVMRLAETKGYRLGNLDATIIAQRPKLAPFIGNMRENIAEACGTDVSRINVKATTTEQLGFEGRGEGISSHAVVLLNKAAHSEER

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.263 kDa
Sequence
MAVGGFEMRIGNGYDFHRLVEGRRLILGGVEIPYRLGLLGHSDADLLTHAITDALLGAACLGDIGRHFPPGDPQWQDVSSLLLLSKVLELVRGRGLRLSNVDAVVVAERPKLAPHIPAIRQSLAGALGLPLDRLSVKATTNEGLGPVGEGLAMACHAVVLLEE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.301 kDa
Sequence
MSLFRIGHGFDVHAFSETGDLIVIGGVNIPHERGLQAHSDGDVLLHAICDALLGAAAFGDIGKHFPDTDPSFSGADSRNLLRSVVSKLHQKGYKIGNIDGTIVAQAPKMAPHIESMRVNIASDCNVSIDCINVKATTTEKLGYTGRKEGIACHAVALLEAQKN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Halorhodospira halophila (strain DSM 244 / SL1)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.971 kDa
Sequence
MIRIGQGFDVHRFAGKGEGFRLGGVAVPYHKRLEAHSDGDVLLHAITDGLLGACGMGDIGRHFPDDDPRWRDADSIGLLASTLRLAAEAGWVPVNVDGTVIAQAPKLAPYIGAMRQATADAMELSPGAVNVKATTSERLGFTGRGEGIAAMAVVLVESAPGRG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.263 kDa
Sequence
MAVGGFEMRIGNGYDFHRLVEGRRLILGGVEIPYRLGLLGHSDADLLTHAITDALLGAACLGDIGRHFPPGDPQWQDVSSLLLLSKVLELVRGRGLRLSNVDAVVVAERPKLAPHIPAIRQSLAGALGLPLDRLSVKATTNEGLGPVGEGLAMACHAVVLLEE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.301 kDa
Sequence
MSLFRIGHGFDVHAFSETGDLIVIGGVNIPHERGLQAHSDGDVLLHAICDALLGAAAFGDIGKHFPDTDPSFSGADSRNLLRSVVSKLHQKGYKIGNIDGTIVAQAPKMAPHIESMRVNIASDCNVSIDCINVKATTTEKLGYTGRKEGIACHAVALLEAQKN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Halorhodospira halophila (strain DSM 244 / SL1)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.971 kDa
Sequence
MIRIGQGFDVHRFAGKGEGFRLGGVAVPYHKRLEAHSDGDVLLHAITDGLLGACGMGDIGRHFPDDDPRWRDADSIGLLASTLRLAAEAGWVPVNVDGTVIAQAPKLAPYIGAMRQATADAMELSPGAVNVKATTSERLGFTGRGEGIAAMAVVLVESAPGRG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.21 kDa
Sequence
MRIGYGYDVHGLVPGRKLVLGGVTIPYDRGLAGHSDADVLLHALADALLGAAALGDIGHYFPPGDPRYKDADSMLLLREVYRHVQTAGYRLANADATITAQEPRLAPYIDAMRERIAAALGVTKEQISVKATTTEGLGFTGRGEGISAQAVVLLLDREAGAGL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.201 kDa
Sequence
MSFNFRIGQGYDVHAFGPGDHLMLGGVRMAHSHGVLAHSDGDVVLHALCDAMLGGLALGDIGVHFPPSDARWKGADSAQFVQHCDQLLRDRGWRVGNADITVICERPKVGPHALAMRERIAGLLAIELDAVSVKATTSEKLGFTGRSEGIAAQAAVLLGKIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas campestris pv. campestris (strain B100)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.201 kDa
Sequence
MSFNFRIGQGYDVHAFGPGDHLMLGGVRMAHSHGVLAHSDGDVVLHALCDAMLGGLALGDIGVHFPPSDARWKGADSAQFVQHCDQLLRDRGWRVGNADITVICERPKVGPHALAMRERIAGLLAIELDAVSVKATTSEKLGFTGRSEGIAAQAAVLLGKIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.201 kDa
Sequence
MSFNFRIGQGYDVHAFGPGDHLMLGGVRMAHSHGVLAHSDGDVVLHALCDAMLGGLALGDIGVHFPPSDARWKGADSAQFVQHCDQLLRDRGWRVGNADITVICERPKVGPHALAMRERIAGLLAIELDAVSVKATTSEKLGFTGRSEGIAAQAAVLLGKIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.297 kDa
Sequence
MSFNFRIGQGYDVHAFGPGEHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDERWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIAGLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.297 kDa
Sequence
MSFNFRIGQGYDVHAFGPGEHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDERWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIAGLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.297 kDa
Sequence
MSFNFRIGQGYDVHAFGPGEHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDERWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIAGLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium jeikeium (strain K411)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.228 kDa
Sequence
MNTPHIIPRVGIATDAHQVQPGKDCWMACLLWEDQDGCEGHSDGDVVAHAVVDALLSAAGLGDLGSFVGVGRQEYDNVSGERLLRECRELLESKGFVIGNAAVQMVGNRPKMGTRREEAEKVMGELIGAPVSVSATTTDHMGFTGRGEGVAAVATAVVWQAQN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.626 kDa
Sequence
MVVQIRIGQGMDVHAFEEGDHVTLAGIKIPHTHGLKAHSDGDVVLHALSDALLGALALGDIGQHFPDTDVQFKGADSRVLLKHVYQLILDRGYALNNADITVACERPKLAKYNLEMRQSIADVLDVDVTQISVKATTTEKLGFTGRQEGILATATVLVSYQAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.856 kDa
Sequence
MMIRIGFGYDVHPLVEGRKLIIGGVEIPFTKGLLGHSDADVLYHAIADAFLGSLALGDIGQLFPDNDERYRGIDSGLLLQEVYRRVRERGYCLNNLDAVIVAQKPKLLPFIQKMRENLAVLLNTAIENISVKATTTEGLGFAGREEGIAAYAVITVKEVLENG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Length
163 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.303 kDa
Sequence
MKKIRIGQGFDIHPLVVGRDLIIGGVTIPYEKGLLGHSDADVLLHALCDALLGAAALGDIGRHFSDTDARYQGIDSRKLVREVHRLLTEAGYRVVNIDATIIAQVPKMAPHIPGMVTNIAQDLTLPAGDINIKAKTAEKLGVVGRGEGIVAEVVCLIADGDEV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.097 kDa
Sequence
MTLRIGHGFDVHRFGDGDHLMIGGVRIPYVQGFVAHSDGDVLLHAICDALLGACALGDIGRHFPDTDAAWAGADSRDLLRHVHTLVMAAGYAVANLDATVIAQAPRMAEHIPAMRACIAEDLDLDTTAVNVKATTSERLGFTGRKEGIAAEAVVLLMPTGTT

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.346 kDa
Sequence
MLPSIRVGLGTDVHPIEAGRPCWLLCLLFDDADGCAGHSDGDVAAHALCDALLSAAGMGDIGEVFGTGLPQWRGVSGADMLRHVHSMMTAEGLRVGNAAVQVIGNRPKIGPRRAEAQRVLSGILGAPVSVSATTTDGLGLTGRGEGLAAIATALVVGDEGKG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella avium (strain 197N)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.905 kDa
Sequence
MTIPFRVGQGFDVHALVTGRPLIIGGVRIEHSHGLLGHSDADVLLHAVTDAILGAAGLGDIGRHFPDTDPRFKGADSRVLLREAMARVDAAGWQVVNVDATVHAQAPKIGPHAPAMVANIAADLGIAHDLVNIKAKTNEGLGYLGRKEGIAATVVTLLARQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.599 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDQAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.568 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDPAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.484 kDa
Sequence
MNVPFRVGQGYDVHALVAGRPLIIGGVTIPHTHGLQGHSDADVLLHAVTDALLGAAGLGDIGRHFPDTDPAYRGADSRVLLRDAVAKVRAAGWAPVNIDATVHAQAPKIGPHAGAMVANIAADAGIDSASVNIKAKTNEGLGYLGRKEGIAATVVALLARAS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.568 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDPAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus somnus (strain 129Pt)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.275 kDa
Sequence
MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDAMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVALLIKQTGTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Histophilus somni (strain 2336)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.332 kDa
Sequence
MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDSMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVVLLIKQNGTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis (strain Pestoides F)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella avium (strain 197N)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.905 kDa
Sequence
MTIPFRVGQGFDVHALVTGRPLIIGGVRIEHSHGLLGHSDADVLLHAVTDAILGAAGLGDIGRHFPDTDPRFKGADSRVLLREAMARVDAAGWQVVNVDATVHAQAPKIGPHAPAMVANIAADLGIAHDLVNIKAKTNEGLGYLGRKEGIAATVVTLLARQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.599 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDQAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.568 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDPAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.484 kDa
Sequence
MNVPFRVGQGYDVHALVAGRPLIIGGVTIPHTHGLQGHSDADVLLHAVTDALLGAAGLGDIGRHFPDTDPAYRGADSRVLLRDAVAKVRAAGWAPVNIDATVHAQAPKIGPHAGAMVANIAADAGIDSASVNIKAKTNEGLGYLGRKEGIAATVVALLARAS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.568 kDa
Sequence
MNIPFRVGQGFDVHALVEGRPLIIGGVTIAHTHGLLGHSDADVLLHAVTDALLGGAGLGDIGRHFPDTDPAYRGADSRVLLRAAFDKVRAAGWAPVNVDATIHAQAPKIGPHAAAMVANIAADLALDAGAVNIKAKTNEGLGYLGRKEGIAANVVVLLARAG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus somnus (strain 129Pt)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.275 kDa
Sequence
MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDAMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVALLIKQTGTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Histophilus somni (strain 2336)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.332 kDa
Sequence
MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDSMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVVLLIKQNGTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis (strain Pestoides F)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Azoarcus sp. (strain BH72)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.62 kDa
Sequence
MKCPFRVGQGFDVHALVPGRALIVGGVDIPFSAGLLGHSDADVLLHALTDALLGAAGLGDIGRLFPDTDPAHAGADSRVLLREAYARVKAAGWEAVNVDATLICRAPRILPHAPAMVVNIAADLGMDAAAINIKGKTTEKLGFTGRGEGIAAQVVALLARAD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Laribacter hongkongensis (strain HLHK9)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.397 kDa
Sequence
MNLRIGQGWDVHRLVEGRPLVLGGVTIPFDKGLDGHSDADALCHAITDALFGAAALGDIGRHFPDTDLEFKGADSRVLLREAVRRVREAGFDIVNVDSTVIAQAPRLAPYVEAMRSHLAADLGLSPDRVNVKAKTSERLGHLGRGEGIAADAVCLLQSRLQE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.599 kDa
Sequence
MFRVGNGIDFHKLIHEPFRPLVLAGVEIKSEFAFLGHSDADVILHAVADAILGALSLGDIGVHFPDTDPQYKNMKSTRIIEKCLELVAEKKFKLINVDCTYVGDHPKISPIRAELNASLANITKLPLDCVSIKATTSEGMGALGRSEGVMVMATVLIESLKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.599 kDa
Sequence
MFRVGNGIDFHKLIHEPFRPLVLAGVEIKSEFAFLGHSDADVILHAVADAILGALSLGDIGVHFPDTDPQYKNMKSTRIIEKCLELVAEKKFKLINVDCTYVGDHPKISPIRAELNASLANITKLPLDCVSIKATTSEGMGALGRSEGVMVMATVLIESLKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.261 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRALLREAYRRILAKGYRLGNLDITIIAQAPKMAPHIPQMRVHLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVALLIKVEQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.182 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.129 kDa
Sequence
MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRCILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.863 kDa
Sequence
MTQPIIPRVGIASDAHQVEPGKPCWMAGLLFEDADGCEGHSDGDVVSHVIVDALLSASGLGDLGSFVGVGRKEYDGVSGERLITECRQLLAENGFTIGNVAAQMIGNRPKMGPRREEAERRLTELVGAPVSVSATTTDKMGFTGRGEGVAALATAVVWKAGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia mallei (strain NCTC 10247)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia mallei (strain NCTC 10229)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia mallei (strain ATCC 23344)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia mallei (strain SAVP1)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia pseudomallei (strain 1106a)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia pseudomallei (strain 1710b)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia pseudomallei (strain 668)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia pseudomallei (strain K96243)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.175 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.117 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECAARVAQAGFSIRNVDSTIIAQAPKLAPHIDAMRANIAADLGLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.744 kDa
Sequence
MRVGFGYDVHKLVEGRPLVLGGVSIPFVKGLLGHSDADVLAHAVMDALLGAAGAGDIGRHFPDNDGRYKGISSMKLLARVGDILSRQGLAVVNIDSVVVAQGPKLSPFIEEMQKRMAGALQIQPSQVSVKATTTEGLGFAGKGEGIAAYAVALVHKTGQAAT

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Petrotoga mobilis (strain DSM 10674 / SJ95)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.567 kDa
Sequence
MLKIGFGYDVHPFAENRRLILGGVVINHPKGYGLLGHSDGDVFFHALIDSLLGMCGLGSIGEYFPESKEFENISSSILLEKTIDLINKRYIVKINNIDVVIISKSVNISSITGQIKNNTSCILNLEVSRINLKGKSGNGLGVGGNDQGIEVYCTILGEIDEI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.622 kDa
Sequence
MKKPFRIGFGFDVHRLSEGYPLWMGGVRLEHSKGLEGHSDADVLIHAICDALLGAAALRDIGYHFPPSDPQYKGIDSKILLARAMELVRSQGYELGNIDATIAAEQPKLNPHIPDMQRVLAEVIQVEVSDISLKATTTEKLGFTGREEGISAYAVALLIAAV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.65 kDa
Sequence
MKKPFRIGFGFDVHRLSEGYPLWMGGVRLEHSKGLEGHSDADVLIHAICDALLGAAALRDIGYHFPPSDPQYKGIDSKILLARVMELVRSQGYELGNIDATIAAEQPKLNPHIPDMQRVLAEVIQVEVSDISLKATTTEKLGFTGREEGISAYAVALLIAAV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Length
162 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.327 kDa
Sequence
MNLRIGHGYDVHKFGDSGPITICGVKIDYEQGLLAHSDGDVALHALCDALLGALALGDIGGHFPDTDAQFKGADSRALLRHVMTLVNEHGYEIGNLDLTIVAQAPKMAPHIQAMRENIRQDVNAQLNQVNVKATTTEKLGFAGRKEGIACYAVVLLNKSIAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.79 kDa
Sequence
MTAALLPRVGIGVDVHPFSPDRPLWLAGLHWPGEPGLAGHSDADVVIHALCNALLSAAGLGDLGTQFGTAEPEWRDAAGTRLLTETVRLVRDAGYAVGNAAVQLLGERPKLRERRTEAEQLLTETVGAPIALSAATTDGLGFLGRRDGLAAVATALVFPAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.92 kDa
Sequence
MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.92 kDa
Sequence
MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.513 kDa
Sequence
MYRIGNGIDFHRLEINPNRPLVLGGVECESEVALVGHSDADIILHAISDAILGALALGDIGQYFPDTDPKLKNIDSKIILAKCLELMKERNFQLVNVDCTVIGEKPKIAPLKEKIKKSLCSLLDLPVDCVSVKATTTEKMGALGRQEGIGTFCTILLVKNL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.513 kDa
Sequence
MYRIGNGIDFHRLEINPNRPLVLGGVECESEVALVGHSDADIILHAISDAILGALALGDIGQYFPDTDPKLKNIDSKIILAKCLELMKERNFQLVNVDCTVIGEKPKIAPLKEKIKKSLCSLLDLPVDCVSVKATTTEKMGALGRQEGIGTFCTILLVKNL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.622 kDa
Sequence
MYRIGNGIDFHKLEINLNRPLILGGIECESEFALVGHSDADIILHAISDAILGALALGDIGQYFPDTDPSLKNIDSKIILVKCLELMKEKNFDLVNIDCTVIGERPKIAPLKDRITKSLSNLLNLPLDCISVKATTTEKMGALGRQEGIGTFCSILLEKRS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.652 kDa
Sequence
MYRIGNGIDFHKLEINLNRPLILGGIECESEFALVGHSDADIILHAISDAILGALALGDIGQYFPDTDPSLKNIDSKIILVKCLELMKEKNFDLVNIDCTVIGERPKITPLKDRITKSLSNLLNLPLDCISVKATTTEKMGALGRQEGIGTFCSILLEKRS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cyanothece sp. (strain PCC 7425 / ATCC 29141)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.23 kDa
Sequence
MTSIRIGNGYDIHRLVSDRPLILGGVNIPHELGLLGHSDADVLTHAIMDALLGALSLGDIGHYFPPGDPQWAGADSLKLLAQVHQLVQERGWQVGNIDSVIVAERPKLKPHLAAMRDRLSAVLKVKPDQIGIKATTNEKLGPEGREEGICAYAVAVLVSVA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salinispora arenicola (strain CNS-205)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.022 kDa
Sequence
MVIVPRVAIGVDTHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAADLGDLGANFGVGQPEWSGASGVALLTESASRVRAAGYAIGNVSVQVIGNRPKIGSRRAEAQRVLSGAVGAPVSISAATTDGLGFPGRGEGLTGIAVALVYEAPDA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.816 kDa
Sequence
MTGLPFRIGYGEDAHRLAPGLPLVLGGVAIPHAELGAVAHSDGDAVLHAVADALLSGLALGDIGQYFPDTAAEWKGMDSRRILAKALELVEERGYRPVNVALVVTLDRPKLGPLRADIAASVAELLGLPAGEVGVSFKTSEGLALEHVQTRVTVLLGRVDD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.119 kDa
Sequence
MVIVPRVAIGVDMHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAAELGDLGANFGVGQPEWSGASGVALLSESARRVRTAGYTIGNVSVQVIGNRPKIGPRRAEAQQVLSAAVGAPVSVSAATTDGLGFPGRDEGLTGIAVALVYAAPAA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella baltica (strain OS223)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.258 kDa
Sequence
MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGALALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQVPKMAPHIEAMRQILAADLTSELDDINVKATTTEHLGFTGRKEGIAVEAVVLMTRKHD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella baltica (strain OS155 / ATCC BAA-1091)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.265 kDa
Sequence
MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHFPDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLTSELDDINVKATTTEQLGFTGRKEGIAVEAVVLMTRKHD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella baltica (strain OS185)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.265 kDa
Sequence
MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHFPDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLTSELDDINVKATTTEQLGFTGRKEGIAVEAVVLMTRKHD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella baltica (strain OS195)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.265 kDa
Sequence
MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHFPDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLTSELDDINVKATTTEQLGFTGRKEGIAVEAVVLMTRKHD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.226 kDa
Sequence
MNIRIGHGFDVHKFGGELPLILGGVEVPYDTGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDPDFKGADSRVLLRHCYQLALDKGYRLGNLDVTIIAQAPKMLPHIQAIRECLSADLESDIEAINVKATTTEKLGFTGRKEGIAVEAVVLMCAAPR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.447 kDa
Sequence
MKIRIGHGFDVHKFGEVRPLILCGVEVPYETGLVAHSDGDVVLHAVSDAILGAMALGDIGKHFPDTDTAYKGADSRVLLRHCYDLAKQRGFELGNVDVTIIAQAPKIAPHIEAMRQVLATDLMAELDDINVKATTTEKLGFTGRKEGIAVEAVVLMSRKQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acaryochloris marina (strain MBIC 11017)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.37 kDa
Sequence
MTSIRIGNGYDIHQLVEGRPLILGGVQIEHSLGLKGHSDADVLTHAIMDALLGALSLGDIGHYFPPTDPKWAGADSLKLLEQVHQLILDRGWQIGNIDSVVVAERPKLKPHIEAMRDRISQVLNLSPELIGIKATTNEKLGPVGQEQGICSYAVALLTSDS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.411 kDa
Sequence
MTALRIGNGYDIHRLVGDRPLILGGVTIAHHLGLDGHSDADVLTHALMDALLGALSLGDIGHYFPPSDARWQGADSLKLLAQVHQLILERGWRINNLDNVIVAEQPKLKPHIQAMKENLAKVLTIDPDLIGIKATTNERLGPTGREEGIAAYSVALLIKEG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermosynechococcus elongatus (strain BP-1)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.323 kDa
Sequence
MMKIRIGNGYDIHRLVPERPLILGGIRLEHACGLLGHSDADVLTHAIMDALLGALSLGDIGHYFPPSDPQWAGADSQVLLAKVAALIAERGWRVGNIDAVVVAERPKLKPYLDPMRDRLATTLGIDRDQISIKATTNEKLGPVGREEGIAAYAVALLQSGM

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.768 kDa
Sequence
MRTGLGYDLHRLVRGKKLMMGGVHIPFKKGEKAHSDGDVLLHAITDALLGACGMGDIGEFFPPSDKKWKDANSSELLSTVWERISEAGWKIQNIDCVIIIEEPKILPFREEIRKSIAGILKIEKEQIFIKAKTGEGIGIIGRGKAVAALASCLIFCRHTQE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.743 kDa
Sequence
MKIRVGFGYDVHALVPDRELWLGGIKIEHTLGLLGHSDADVLIHAICDALLGAANMRDIGYHFPDTAGEYKNIDSKILLRDTMRLLREAGYELGNIDATVAAERPKLNPHIPLMKKTLAEVMNVDEEDISIKATTTEKLGFTGRQEGISAYATVLIQRMGS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella sediminis (strain HAW-EB3)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.252 kDa
Sequence
MNIRIGHGFDVHKFGGGSPLLLGGVHIPYETGLIAHSDGDVVLHAISDAVLGAVALGDIGKHFPDTDEEFKGADSRHLLRHCYRLAKEKGYSMGNLDVTIIAQAPKMAPHIEAIREVLALDFETDTDNINVKATTTEKLGFTGRKEGIAVEAVVLLVKSAD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella sp. (strain W3-18-1)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.447 kDa
Sequence
MKIRIGHGFDVHKFGEVRPLILCGVEVPYETGLVAHSDGDVVLHAVSDAILGAMALGDIGKHFPDTDTAYKGADSRVLLRHCYDLAKQRGFELGNVDVTIIAQAPKIAPHIEAMRQVLATDLMAELDDINVKATTTEKLGFTGRKEGIAVEAVVLMSRKQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.92 kDa
Sequence
MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.92 kDa
Sequence
MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia ambifaria (strain MC40-6)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.848 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECAARVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKAGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia cenocepacia (strain AU 1054)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.923 kDa
Sequence
MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia cenocepacia (strain MC0-3)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.923 kDa
Sequence
MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia cenocepacia (strain HI2424)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.923 kDa
Sequence
MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.923 kDa
Sequence
MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.878 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECAARVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLDRVNVKAKTNEKLGYLGRGDGIEAQAAALLVKEGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.937 kDa
Sequence
MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECVARINAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.877 kDa
Sequence
MDFRIGQGYDVHQLVAGRPLIIGGVSIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECVARVKAAGFAIQNVDSTVIAQAPKLAPHIEAMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Peptoclostridium difficile (strain 630)
Length
161 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.434 kDa
Sequence
MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAIMDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQSPKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQNN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain AYE)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.375 kDa
Sequence
MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.874 kDa
Sequence
MVSVRIGQGFDVHAFDEGDHVMLGGVAIPHSHGLKAHSDGDVALHALSDALLGALALGDIGHHFPDTDPQWRGADSGQLLTAIYSSILDAGWRLGNADLTVICQAPKLAPHILAMRERIAALLQCEQGQVSVKATTTEKLGFTGRKEGIAVQAVVLLESQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.048 kDa
Sequence
MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQVVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neisseria meningitidis serogroup C (strain 053442)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.02 kDa
Sequence
MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.036 kDa
Sequence
MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIESQAAVLLVRI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.02 kDa
Sequence
MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.02 kDa
Sequence
MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALLHAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVIAQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.474 kDa
Sequence
MKIRVGFGFDVHQLVTGRELWLGGIKFEHELGLLGHSDADVLIHAICDALLGAANMRDIGYHFPDTAGEFKNIDSKILLAETVDLIAAKGYKVGNVDATICAERPKLKARIPEMQLVLAHLMRIDVDDVSVKATTTEKLGFTGREEGISAYATVLIEKAE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.419 kDa
Sequence
MFRIGQGFDVHQFVEGRPLIIGGVHIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGRHFPDTDPRYKDADSAELLAHVWSLVRQEGYVLVNADCTIIAQKPKMAPYIEEMKKVIARLLEAERSQVNVKATTTEKLGFTGREEGVAAQVVVLLQKSEA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.437 kDa
Sequence
MIRIGHGFDVHAFGEKRPLIIGGVTIPYHTGFIAHSDGDVALHALTDALLGAAALGDIGKLFPDTDQQYKNIDSRKLLIEAYRQVQTKGYQISNIDITIIAQAPKMRPHIDNMRQLIANDLNCDIDQINIKATTTEKLGFTGRGEGIACEAVALLSKKTV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.474 kDa
Sequence
MKIRVGFGFDVHQLVTGRELWLGGIKFEHELGLLGHSDADVLIHAICDALLGAANMRDIGYHFPDTAGEFKNIDSKILLAETVDLIAAKGYKVGNVDATICAERPKLKARIPEMQLVLAHLMRIDVDDVSVKATTTEKLGFTGREEGISAYATVLIEKAE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.419 kDa
Sequence
MFRIGQGFDVHQFVEGRPLIIGGVHIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGRHFPDTDPRYKDADSAELLAHVWSLVRQEGYVLVNADCTIIAQKPKMAPYIEEMKKVIARLLEAERSQVNVKATTTEKLGFTGREEGVAAQVVVLLQKSEA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.437 kDa
Sequence
MIRIGHGFDVHAFGEKRPLIIGGVTIPYHTGFIAHSDGDVALHALTDALLGAAALGDIGKLFPDTDQQYKNIDSRKLLIEAYRQVQTKGYQISNIDITIIAQAPKMRPHIDNMRQLIANDLNCDIDQINIKATTTEKLGFTGRGEGIACEAVALLSKKTV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.172 kDa
Sequence
MIRVGNGFDVHQLVEGRPCIIGGVEIPFAKGLKGHSDADVLLHAVSDALLGAAALGDIGKHFPDTDERFKDADSRVLLRHVVALLKAKHYNIVNIDATIIAEAPKMAPHIARMVQHIAEDCDILADCVNVKATTSEKMGFVGRGEGIAAQAVCLIQKYQI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.586 kDa
Sequence
MTNTPIIPRVGIATDAHQIEAGKPCWIACLLFSGADGCEGHSDGDVVAHALVDALLSAANLGDLGSFVGVGRKEYDGVSGTQLLTECRELLESHGFTIGNGAVQLVGQSPKMGPRREEAERVMSEILGAPVSVSATTTDHLGFTGRSEGRAAVATAVVWK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium glutamicum (strain R)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.671 kDa
Sequence
MTNPIIPRVGIATDAHQIEAGKPCWIACLLFEGVDGCEGHSDGDVIAHAIVDALLSASGLGDLGSFVGVGRPEYDGVSGTQLLKEVRELLESRGFVIGNVAAQLVGQTPKFGPRREEAQQVISDIIGAPCSLSATTTDHMGFTGRSEGRASVATAVVWKV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.582 kDa
Sequence
MTNPIIPRVGIATDAHQIEAGKPCWIACLLFEGVDGCEGHSDGDVVAHAIVDALLSASGLGDLGSFVGVGRPEYDGVSGTQLLKEVRELLSAHGYVIGNVAAQLVGQTPKFGPRREEAQQVISEIIGAPCSLSATTTDHMGFTGRSEGRASVATAVVWKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Dechloromonas aromatica (strain RCB)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.934 kDa
Sequence
MNFRVGQGYDVHKLVDGRKLILGGVEIPHPTGLLGHSDADALLHAITDALLGAVALGDIGRHFPDTDPRYKGADSRVLLRAAVALLAERGWRPVNVDATLIAQQPKLAPHAVAMVANVAADLGISPDCVNIKGKTNERLGYLGREEAIEAQAVALVERVG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.279 kDa
Sequence
MKIRIGHGFDVHKFGADRPLILCGIEVPYETGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYEGADSRVLLRHCFKLAREHGFAIGNLDVTIIAQAPKMLPHIEAMRAVLADDLQTELNNINVKATTTEKLGFTGRKEGIAVEAVVLMENVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.145 kDa
Sequence
MKLRIGHGFDVHKFGGDKPLILGGVTVPYDTGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDDAFSGADSRVLLRHCYQLALNKHFQLGNLDVTVIAQAPKMAPHIEAIRQLLALDLNTDIDNINVKATTTEKLGFTGRKEGIAVEAVVLMQQAI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain AB307-0294)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.375 kDa
Sequence
MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain AB0057)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.375 kDa
Sequence
MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain ACICU)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.375 kDa
Sequence
MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain SDF)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.389 kDa
Sequence
MVAQIRIGQGMDVHAFEEGKFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.375 kDa
Sequence
MVAQIRIGQGMDVHAFEEGNFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Frankia alni (strain ACN14a)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.977 kDa
Sequence
MTTAVLPRVGIGVDVHPFAAGRPCWVACLEWPGETGLAGHSDGDVAAHATCDALLTASCLGDLGKVFGTDRPEYAGASGAVLLAETARLLAVGGWVIGNVSVQVIGNRPRMAARREQAQAAMSAALGASVSLSATTTDGLGLTGRGEGLAAIATALVVRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.032 kDa
Sequence
MNTVILPRVGVGVDVHPFAAGRPCWVACLEWPGETGLAGHSDGDVAAHAACDALLTASCLGDLGRVFGTDRPEYAGASGAVLLAETARLLGAAGWAIGNVSVQVIGNRPRMAGRREDAQKAMSVALGASVSLSATTTDGLGLTGRGEGLAAIATALVIRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Frankia sp. (strain EAN1pec)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.07 kDa
Sequence
MTEPSLPRVGTGVDVHPFEQGRECWVACLLWPGETGLAGHSDGDVASHAACDALLTASGIGDLGAVFGTGRPEWSGASGAALLGETARLLAEGGWLIGNVAVQVVGNRPRMAARRVEAQEAMSAALGAPVNLSATTTDGLGLTGRGEGLAAIATALVTRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.687 kDa
Sequence
MLRIGNGYDVHKLVEGRKLMLGGVEVPHTKGVLGHSDGDVLLHAITDAIIGALGLGDIGLHFPDNDENLKDIDSAILLKKINNIMKEKNYKIVNLDSIIVMQKPKLRPYIDSIRDNIAKILEINSELINVKAKTEEKLGFTGDETGVKSYCVVLLEKKKC

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.431 kDa
Sequence
MSRFRIGNGYDIHRLVEGRPLILGGIQLEHSLGLDGHSDADVLTHAIMDALLGALSLGDIGHYFPPTDPQWKGADSLKLLAQVNQLIRDRGWTIGNLDSVVVAEQPKLKPHIAAMRDRLAKVLELEPDQIGIKATTNEKLGPTGREEGICAYAVALLVRD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thiobacillus denitrificans (strain ATCC 25259)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.176 kDa
Sequence
MREMRVGHGYDVHVLVENRRLIIGGVEIPYERGLAGHSDADVLLHAICDALLGAVGLGDIGRHFPDTDAAFAGIDSRILLRRVAQQLKERAWQVGNVDATIIAQAPKMAPHIARMTAHIADDLGVAIDRVNVKATTTERLGFAGRGEGIAAEAVCLIERG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thioalkalivibrio sulfidiphilus (strain HL-EbGR7)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.858 kDa
Sequence
MANIRIGHGYDVHAFKAGGHVVLGGVRIPHAKAFAAHSDGDVLIHALCDALLGAAALGDIGRHFPDTDPAYKGADSRVLLRRVVELLHEQGYRVGNVDATIIAQAPKMAPHIEAMRANLADDLGVALECVNVKATTTERLGFAGREEGIAAHAVALIESF

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Uncultured termite group 1 bacterium phylotype Rs-D17
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.531 kDa
Sequence
MYIGFGYDAHRLKKGRELILGGVKILTSEGLDGHSDADVLIHALMDALLGAAGLNDIGHFFPDMDPKYKNVSSISLLESVYKELKKQNFSVNNVDITVIVEAPKICPFIADMKENISRVIELKRERIGIKATTNEKMGFVGRGEGIAAVAVASISQEKKR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.692 kDa
Sequence
MGKMRVGIGYDVHRFEEGKKLMLGGIEIPFEKGLKGHSDGDVLIHALIDGILGAAGLGDIGEHFPDTDVAYKEVDSKILLKRVLELVSEHYVVNNVDCIVVTERPKLSPYKDRIRTSLAELLGVSKERVNVKAKTEEGLGFTGREEGIKAYAVVLLEERY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.459 kDa
Sequence
MTKIRIGNGYDIHQLVSDRVLILGGIQIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGHYFPPSDPKWAGADSLVLLNQVHQLIRDRGWQVGNIDSVVVAERPKLKPHIHNMRDKLAAILELESNQIGIKATTNEKLGPVGREEGICAYAVVLLLKE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechococcus elongatus (strain PCC 7942)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.431 kDa
Sequence
MSRFRIGNGYDIHRLVEGRPLILGGIQLEHSLGLDGHSDADVLTHAIMDALLGALSLGDIGHYFPPTDPQWKGADSLKLLAQVNQLIRDRGWTIGNLDSVVVAEQPKLKPHIAAMRDRLAKVLELEPDQIGIKATTNEKLGPTGREEGICAYAVALLVRD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Proteus mirabilis (strain HI4320)
Length
160 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.17 kDa
Sequence
MRIGHGYDVHKFGGEGPIIIGGVRIPYEQGLLAHSDGDVVLHAVTDAILGAVAMGDIGTLFPDTDPAYKGADSRVLLREAFSRVMAKGYRIGNLDVTIIAQAPKMLPHTPQMRVNIAEDLHCHVDDINVKATTTEKLGFVGRKEGIACEAVVLLIKESLS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.853 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYDKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Aliivibrio salmonicida (strain LFI1238)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.93 kDa
Sequence
MRIGHGFDVHKFGGEGPVIIGGVSVPYEQGLIAHSDGDVALHALCDALLGAIAEGDIGRHFPDTDDKWKGADSRALLRDVYRRVKEKGLELGNADVTIIAQAPKMAPHIKHMCAAIAEDLETSLDNVNVKATTSEGLGFTGRKEGIACEAVVLLVKKSY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Alkaliphilus metalliredigens (strain QYMF)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.999 kDa
Sequence
MRVGIGYDVHRLVEGRKLIVGGVEIPHEKGLLGHSDADVLLHAIKDALLGAVALGDIGKHFPDTDEKYKGESSLYLLNEVGRMLAEKAYVANNIDATIIAQEPKMAPYIELMRRNIAEVLGIKVEQVNIKATTTEGIGFVGRGEGIAAQAIVSVGQSLG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium avium (strain 104)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.957 kDa
Sequence
MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVVPTG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.957 kDa
Sequence
MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVVPTG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.458 kDa
Sequence
MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus clausii (strain KSM-K16)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.956 kDa
Sequence
MIRIGQGFDVHQLTEGRPLLLGGVHIPHPKGLLGHSDADVLLHTITDAALGAIGAGDLGKHFPDTDEAFKDADSKHLLSQAWQLVKNAGYTLGNVDCTVMAQKPKLAPYIEAMRKQIAELLETDVANVSVKATTTETLGFVGREEGIAAQAVILLQKAE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.394 kDa
Sequence
MKIRVGFGFDVHQLVEGRELWLGGIRLEHSKGLLGHSDADVLLHTVCDALLGAANMRDIGYHFPDTAGEYKNIDSKILLKKTVELIATKGYRVGNIDATICAERPKLKAHIPLMQETMAAVMGIDAEDISIKATTTEKLGFTGREEGISAYATVLIEKD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.08 kDa
Sequence
MKIRVGHGYDVHRWGSDKPLILGGVEIEHHQGLVAHSDGDVVLHAVTDAVLGALALGDIGQHFPDTDERYAGADSAELLSHAVSLCQEKEFKTGNIDVTIVAQAPKMAPHIDDMRSSIAQCLKTCIDNVNVKATTTEKLGFVGREEGIACHAVVLMESF

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.816 kDa
Sequence
MSGLPRVGTGVDVHQLVAGRPCWVAGLLWEGEAAGPEGHSDGDVAAHACCDALFAAAGLGDLGAHFGTARPEFAGASGARLLAEAARLVREAGFEIGNVSVQVVGNRPKVGRRRAEAQAALSRACGAPVSVAGTTTDALGLTGRGEGIAAIATALVVPR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Klebsiella pneumoniae (strain 342)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.969 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLRKAEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.955 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLRKADK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus clausii (strain KSM-K16)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.956 kDa
Sequence
MIRIGQGFDVHQLTEGRPLLLGGVHIPHPKGLLGHSDADVLLHTITDAALGAIGAGDLGKHFPDTDEAFKDADSKHLLSQAWQLVKNAGYTLGNVDCTVMAQKPKLAPYIEAMRKQIAELLETDVANVSVKATTTETLGFVGREEGIAAQAVILLQKAE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.394 kDa
Sequence
MKIRVGFGFDVHQLVEGRELWLGGIRLEHSKGLLGHSDADVLLHTVCDALLGAANMRDIGYHFPDTAGEYKNIDSKILLKKTVELIATKGYRVGNIDATICAERPKLKAHIPLMQETMAAVMGIDAEDISIKATTTEKLGFTGREEGISAYATVLIEKD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.08 kDa
Sequence
MKIRVGHGYDVHRWGSDKPLILGGVEIEHHQGLVAHSDGDVVLHAVTDAVLGALALGDIGQHFPDTDERYAGADSAELLSHAVSLCQEKEFKTGNIDVTIVAQAPKMAPHIDDMRSSIAQCLKTCIDNVNVKATTTEKLGFVGREEGIACHAVVLMESF

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.816 kDa
Sequence
MSGLPRVGTGVDVHQLVAGRPCWVAGLLWEGEAAGPEGHSDGDVAAHACCDALFAAAGLGDLGAHFGTARPEFAGASGARLLAEAARLVREAGFEIGNVSVQVVGNRPKVGRRRAEAQAALSRACGAPVSVAGTTTDALGLTGRGEGIAAIATALVVPR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Klebsiella pneumoniae (strain 342)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.969 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLRKAEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.955 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLRKADK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.328 kDa
Sequence
MKIKVGFGFDVHQLVEGRELWLGGILLEHEKGLLGHSDADVLVHAICDALLGAANMRDIGYHFPDNAGEYKNIDSKILLKKTVELIATKGYQIGNIDATICAERPKLKAHIPSMQQVLAEVMGIDADDISIKATTTEKLGFTGREEGISAYATVLINRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacteroides fragilis (strain YCH46)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.298 kDa
Sequence
MKIKVGFGFDVHQLVEGRELWLGGILLEHEKGLLGHSDADVLVHAICDALLGAANMRDIGYHFPDNAGEYKNIDSKILLKKTVELIAAKGYQIGNIDATICAERPKLKAHIPSMQQVLAEVMGIDADDISIKATTTEKLGFTGREEGISAYATVLINRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mannheimia succiniciproducens (strain MBEL55E)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.224 kDa
Sequence
MIRIGHGFDVHAFGEARPLIIGGVEVPYHTGFIAHSDGDVALHALTDALLGALALGDIGKLFPDTDMQFKNIDSRILLREAFRRVQEKGYKIGNVDVTIIAQAPKMRPHIDAMRAVIAEDLQCSVEQVNVKATTTEKLGFTGRSEGITTEAVALLVKSC

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.82 kDa
Sequence
MRIGQGFDVHAFCEGDSVILGGVTIPHSHGLMAHSDGDVLLHALADALLGAVALGDIGHFFPDSSEEWAGADSRDLLRRVMQRVLDEGYAVTNIDTTIIAQAPKMAPHIEAMRMNIAEDLGVPANRVSVKATTTEKLGFTGRGEGIACQAVCLLEAVSQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.757 kDa
Sequence
MRIGHGFDVHAFGGTGPIILGGVRIPYEQGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMAPHIPQMRVFIAEDLGCHMDQVNVKATTTEKLGFTGRGEGIACEAVALLMKAGA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.634 kDa
Sequence
MKIKVGFGYDVHQLKEGRPMWLGGIQLEYTKGPDGHSDADVLIHAICDAILGAANMRDIGFHFANTDDRWKGVDSKVLLKEVCRMIREKGWEISNVDASLALEMPKINPHIERMQTALSEAMSIPVEDISIKATTNEKLGYVGREEGVNAYAVALLIKP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.776 kDa
Sequence
MDIRTGNGFDVHAFGPGDHVWLCGVRVPHHRGLIGHSDADVGMHALTDAIYGALAEGDIGVHFPPSDPQWKGAASRIFLEHAMGRIAARGYTLANCDVTLICERPKIGPVAPAMREALAEIMGIAADRISVKATTSEKLGFTGREEGIAAIATVALLQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.776 kDa
Sequence
MDIRTGNGFDVHAFGPGDHVWLCGVRVPHHRGLIGHSDADVGMHALTDAIYGALAEGDIGVHFPPSDPQWKGAASRIFLEHAMGRIAARGYTLANCDVTLICERPKIGPVAPAMREALAEIMGIAADRISVKATTSEKLGFTGREEGIAAIATVALLQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.782 kDa
Sequence
MDIRTGNGFDVHAFGPGDHVWLCGVRVPHHRGLIGHSDADVGMHALTDAIYGALAEGDIGVHFPPSDPQWKGAASRIFLEHAMGRIAARGFTLANCDVTLICERPKIGPMAPAMREALAAIMGVEVGRISVKATTSEKLGFTGREEGIACIATATLLQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodobacter sphaeroides (strain KD131 / KCTC 12085)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.776 kDa
Sequence
MDIRTGNGFDVHAFGPGDHVWLCGVRVPHHRGLIGHSDADVGMHALTDAIYGALAEGDIGVHFPPSDPQWKGAASRIFLEHAMGRIAARGYTLANCDVTLICERPKIGPVAPAMREALAEIMGIAADRISVKATTSEKLGFTGREEGIAAIATVALLQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.71 kDa
Sequence
MDIRLGNGFDVHAFGPGDHVTLCGVKIPHGQGLVGHSDADVAMHTVTDAIYGALAMGDIGQHFPPSDPQWKGAASDIFLKHAVAQASEQGFEINNVDCTLICEFPKIGPHAQAMREAMARIMGMALSRISVKATTSERLGFTGRGEGIACIATAALVRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella agona (strain SL483)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.928 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYILGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGITCEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella choleraesuis (strain SC-B67)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.914 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPRMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella dublin (strain CT_02021853)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.876 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella enteritidis PT4 (strain P125109)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.876 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.876 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella heidelberg (strain SL476)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella newport (strain SL254)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella paratyphi C (strain RKS4594)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.882 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAAQGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.926 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPTFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPRMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain 55989 / EAEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O157:H7
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O81 (strain ED1a)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.868 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O8 (strain IAI1)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain K12 / DH10B)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella paratyphi A (strain AKU_12601)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella typhi
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.886 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
16.9 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDEVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella frigidimarina (strain NCIMB 400)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.873 kDa
Sequence
MNIRIGHGFDVHKFGGDSPLVLGGVTVPYDSGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDANFAGADSRVLLKHCYQLALQKQFVLGNLDVTIIAQAPKMAPHIEAIRQCLSADLQTDIDNINVKATTTENLGFTGRKEGIAVEAVVLMKSQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella halifaxensis (strain HAW-EB4)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.893 kDa
Sequence
MKIRIGHGFDVHKFGGEPPLILGGVDVPYEVGLIAHSDGDVALHAISDAILGAMALGDIGKHFPDTDPEFKGADSRVLLRHCYQLATDMGFSLSNLDVTIIAQAPKMAPHIEAIRKVLAADLVADINDINVKATTTEKLGFTGRKEGIAVEAVVLMIKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella oneidensis (strain MR-1)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
16.996 kDa
Sequence
MKIRIGHGFDVHKFGEPRPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALAKAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADVADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.947 kDa
Sequence
MKIRIGHGFDVHKFGGEPPLILGGITVPYEVGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDPDFKGADSRVLLRHCYKLAMDMGYSLSNLDVTVIAQAPKMAPHIEAIRAVLAEDLASEICDINVKATTTEKLGFTGRKEGIAVEAVVLMIKS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.903 kDa
Sequence
MKIRIGHGFDVHKFGGEPPLILGGVTVPYEVGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAEFKGADSRVLLKHCYQLALNMGFSMSNLDVTVIAQAPKMAPHIEAIRSVIAADLQSDIDDINVKATTTEKLGFTGRKEGIAVEAVVLMTKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Finegoldia magna (strain ATCC 29328)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.724 kDa
Sequence
MRIGFGLDVHKLVENRKLILGGVEIPHDKGLLGHSDADVLIHAIMDAICGALCLGDIGKLFPDTDMKYKDIDSRVLLRKVFEIMDDMGYEIGNIDSTISCQKPKLRDYIDKMRENIAQDLHTNTFNISVKATTTEQLGFEGRCEGITANSVCILNKKDL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.665 kDa
Sequence
MSFRIGHGYDVHKFTSTKKNIILGGIEIPYEMGLEAHSDGDVLIHALCDAILGALCLGDIGKHFPDTDMEYKNTDSKFFLAEIKKMLDDKEYSISNIDCTIIAQAPKMLPHIEKMKACLASVLEIQINQINIKATTTEQLGFIGRKEGIATHVVCLLNR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. tularensis (strain FSC 198)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.665 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDKKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.666 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. holarctica (strain LVS)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.666 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. mediasiatica (strain FSC147)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.666 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. novicida (strain U112)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.677 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFPDTDNQFKNIDSKFFLAEIKKMLDEKQYSINNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. holarctica (strain OSU18)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.666 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAIIGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
17.665 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDKKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Francisella tularensis subsp. tularensis (strain WY96-3418)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.666 kDa
Sequence
MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.081 kDa
Sequence
MRVGFGYDVHAFVEGRPLVLGGVKVPHDRGLLGHSDADVLLHAICDALLGGAALGDIGRHFPDTDPRFKGISSLLLLRQTVELVRRAGFRIANIDTTLVLQKPRLAPYIARMAEEIGRATDLPVSSVNVKATTTEKLGFAGREEGVAAYAVVLLRSDGR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Cellvibrio japonicus (strain Ueda107)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.154 kDa
Sequence
MSMRIGQGYDVHAFGEGEKIVIGGVVIPHHHGLVAHSDGDVLLHALCDALLGAVALGDIGKHFPDTDMQYRNADSRSLLRMVYAKVSQHGWKLANADMTIVAQAPRMASYIPHMVEVIASDLQSSASQINVKATTSERLGFTGREEGIACYAVVLLESR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobium phaeobacteroides (strain BS1)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.896 kDa
Sequence
MRIGTGIDVHQFAEGRKLIVGGVEIPHSKGLKGHSDADVLLHAISDALLGAAALGDIGKHFPDTSPQFKDIDSMILLQHVGKLIAEEGYAIGNIDSVLVMEKPKVAPHIMAMRGNIAACLDIDVSKVAVKATTTEKLGYVGREEGVAAHAICLIEERKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.881 kDa
Sequence
MDLRIGQGYDVHALVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFPDTATEFKGANSRVLLRECAARIARAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAEDLNLPIDRVNVKAKTNEKLGYLGRGEGIEAQAAALLVRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.743 kDa
Sequence
MDFRIGQGYDVHALVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDAIFGAAAMGDIGRHFSDTDAKFAGADSRVLLRECFARVKAAGFSIANVDSSVVAQAPKLAPHIEGMRANIAADLGLPVERVNVKAKTNEKLGYLGRGEGIEAQAAVLLIKN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Paraburkholderia xenovorans (strain LB400)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.744 kDa
Sequence
MDFRIGQGYDVHALVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAAMGDIGRHFSDTDAKFAGADSRVLLRECFARVTAAGFSIANVDSSVVAQAPKLAPHIEGMRANIAADLGLPVERVNVKAKTNEKLGYLGRGEGIEAQAAVLLIRN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O9:H4 (strain HS)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O1:K1 / APEC
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.926 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPTFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPRMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.924 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVVLHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPRMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.868 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain K12)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). Also converts 4-diphosphocytidyl-2-C-methyl-D-erythritol into 2-C-methyl-D-erythritol 3,4-cyclophosphate and CMP.
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain SE11)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.868 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.926 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPTFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPRMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Enterobacter sp. (strain 638)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.827 kDa
Sequence
MRIGHGFDVHAFGGVGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLTHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLVKAAK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella sp. (strain ANA-3)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.012 kDa
Sequence
MKIRIGHGFDVHKFGEARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADIADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella sp. (strain MR-4)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.012 kDa
Sequence
MKIRIGHGFDVHKFGEARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADIADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella sp. (strain MR-7)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.012 kDa
Sequence
MKIRIGHGFDVHKFGEARPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALARAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADIADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.004 kDa
Sequence
MNIRIGHGFDVHKFGGDSPLLLGGVNVPYETGLIAHSDGDVVLHAISDAVLGAVALGDIGKHFPDTDDDFKGADSRHLLRHCYQLAKDKGFVIGNLDVTIIAQVPKMAPHIQAIREVLSRDFATDLDNINVKATTTEKLGFTGRKEGIAVEAVILLAKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella flexneri serotype 5b (strain 8401)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella flexneri
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Shigella sonnei (strain Ss046)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.898 kDa
Sequence
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Solibacter usitatus (strain Ellin6076)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.449 kDa
Sequence
MSEIRTGLGWDVHRIATGRKMILGGVTVPCEFGLEGHSDADVLAHAITDAILGAAALGDIGMHFPDSDPRWKGCDSLVFLRHARDLATQKGYRIVNVDSTIILERPKLKDFRQTIRERLAETLELDVDRVSVKFKTAEKVGPVGEGRSAESQAIVTLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Syntrophus aciditrophicus (strain SB)
Length
159 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.269 kDa
Sequence
MRVGCGYDSHRWAAKRKLILGGVEIPHEFGLTGHSDADALTHAICDALLGAISEGDIGFQFPDSDPAYSGISSLKLLSKILEMVDKKGFAIDYIDSTVIMERPKLMPYIPDMKSKIAGVLKMPSDRINIKAKTNEGMGFVGRQEGVAVFAVALVKENQD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.6 kDa
Sequence
MFRIGQGYDVHQLVEGRPLILGGVDIPHDKGLLGHSDADALLHAITDALLGAAALGDIGRHFPDTAAEFKGADSRALLREAAARVRAAGWRPVNVDSTLIAQRPKLAPHIDAMRANIAADLGLDVGAVNVKGKTNEKLGYLGRCEAIEAQAVCLLAQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.063 kDa
Sequence
MRIGLGYDVHRLVENRKLILGGVEIPYEKGLLGHSDADVLIHAIIDSLLGACALGDIGKHFPDTDSRFSGISSIILLEETGKLLLKSGYAINNIDATIIAQKPKMLPHIENMRKNISIALNIDINKINIKATTEEGLGFTGEMLGISSQSISSVESII

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.291 kDa
Sequence
MRVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVFGTGRPEWDGVSGARMLAEVRRLLEENQFTVGNAAVQVIGNRPKIGPRRGEAQKVLSDILGAPVSVSATTTDGLGLTGRGEGIAAMATALVMTTEHDR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodococcus jostii (strain RHA1)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.174 kDa
Sequence
MRVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVFGTGRPEWSGVSGAAMLAEVRRLLEEDDFDVANAAVQVIGNRPKIGPRRNEAQKVLSDILGAPVSVSATTTDGLGLTGRGEGIAAMATALVIPGRSAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Actinobacillus pleuropneumoniae serotype 5b (strain L20)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.245 kDa
Sequence
MIRIGHGFDVHAFGQDRPLMICGVEVPYHTGFIAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVRAQGYKVANVDVTIIAQAPKMRPYIDQMRQTIADDLQCDAMQVNVKATTTEKLGFTGRGEGIACEAVALLIKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.273 kDa
Sequence
MIRIGHGFDVHAFGQDRPLMICGVEVPYHTGFIAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVRAQGYKVANVDVTIIAQAPKMRPYIDQMRQTIADDLQCDVMQVNVKATTTEKLGFTGRGEGIACEAVALLIKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Actinobacillus pleuropneumoniae serotype 3 (strain JL03)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.245 kDa
Sequence
MIRIGHGFDVHAFGQDRPLMICGVEVPYHTGFIAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVRAQGYKVANVDVTIIAQAPKMRPYIDQMRQTIADDLQCDAMQVNVKATTTEKLGFTGRGEGIACEAVALLIKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / 130Z)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.008 kDa
Sequence
MIRIGHGFDVHALGEARPLIIGGVKVPYHTGFIAHSDGDVVLHALTDALLGAVALGDIGKLFPDTDMQFKDIDSRILLREAFRRVKEKGYAVGNVDVTIIAQAPKMRPYIDAMRAVIAEDLQCGIDQVNVKATTTEKLGFTGRSEGIATEAVVLLVKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.83 kDa
Sequence
MRIGHGFDVHKFGGEGPVIIGGVSVPYEQGLIAHSDGDVALHALCDALLGAIAEGDIGRHFPDTDDKWKGADSRALLRDVYRRVKEKGFALGNADVTIIAQAPKMAPYIQAMCNAIAEDLETELDNVNVKATTSERLGFTGRKEGIACEAVVLLVKAS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Aliivibrio fischeri (strain MJ11)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.832 kDa
Sequence
MRIGHGFDVHKFGGEGPVIIGGVSVPYEQGLIAHSDGDVALHALCDALLGAIAEGDIGRHFPDTDDKWKGADSRALLRDVYRRVKEKGFVLGNADVTIIAQAPKMAPHIQAMCNAIAEDLETELDNVNVKATTSERLGFTGRKEGIACEAVVLLVKAS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.942 kDa
Sequence
MNALPRVGIGTDVHPIEEGKPCWLLGLLFSDENGCEGHSDGDVAAHALCDALLSAAGLGDVGAVFGTGRPEWTGVSGAKMLSHVRDLLHDNGFQIGNAAVQVIGNRPKVGPRRAEAQELLSGLIGAPVSVSATTTDGLGLTGRGEGLAAVATALVTAL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium leprae (strain Br4923)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.511 kDa
Sequence
MSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycobacterium leprae (strain TN)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.511 kDa
Sequence
MSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.337 kDa
Sequence
MRIGHGVDVHKLVKGEDLVLGGVQIPSDLGLKGHSDADVLIHAIMDAMLGSLALGDIGKHFPDDDPRYHQIDSKVLLKKTYQLITSYGYQLINLDSTIMAEKPKLAPYIDEMRITISDVLDLYPSQIGIKATTFEKLGFVGSGQGIMAQAVVLMERLY

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.188 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLRHVWMIVKEKGYTLGNLDCTIIAQKPKMAPYIEDMRARIAEGLEAEISQINVKATTTEKLGFTGRAEGIAAQASVLLQKV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus pumilus (strain SAFR-032)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.145 kDa
Sequence
MLRIGQGFDVHQLTEGRPLIIGGVTIPYEKGLLGHSDADVLLHTVADACLGAIAEGDIGRHFPDTDPEFKDADSFQLLQHVWALVKEKGYTLVNIDCTIMAQKPKMAPYIQPMCEKIAEALEADVTQVNVKATTTEKLGFTGRGEGIASQATVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus subtilis (strain 168)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.126 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.046 kDa
Sequence
MFRIGQGFDVHQLTEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAAGEGDIGKHFPDTDPEFKDADSFKLLQHVWNIVKEKGYVLGNIDCTIIAQKPKMAPHIDAMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Brachyspira hyodysenteriae (strain ATCC 49526 / WA1)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.489 kDa
Sequence
MRIGYGYDSHAFAENRKLILSGIEIPYELGLKGHSDADAVIHALIDSILGALALGDIGSHFPDNDSKYKGISSIVLLEKTVSIMEEKNYEISNTDITIILEKPKLRNYIDTMRENLSKILKTDIENVSIKAKTNEKMDSIGRGEGIAVHCVSLLKKTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacillus sp. (strain WCH70)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.161 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGVRIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGKHFPDTDECYKDADSALLLKQVWELVKQQGYELANLDCTIIAQKPKMAPHIEQMKENIANLLEGELSQVNVKATTTEKLGFTGREEGIAAQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain 86-028NP)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.179 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDILCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain PittEE)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain PittGG)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.188 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLRHVWMIVKEKGYTLGNLDCTIIAQKPKMAPYIEDMRARIAEGLEAEISQINVKATTTEKLGFTGRAEGIAAQASVLLQKV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus pumilus (strain SAFR-032)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.145 kDa
Sequence
MLRIGQGFDVHQLTEGRPLIIGGVTIPYEKGLLGHSDADVLLHTVADACLGAIAEGDIGRHFPDTDPEFKDADSFQLLQHVWALVKEKGYTLVNIDCTIMAQKPKMAPYIQPMCEKIAEALEADVTQVNVKATTTEKLGFTGRGEGIASQATVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus subtilis (strain 168)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.126 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAVGEGDIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVLGNIDCTIIAQKPKMLPYIEDMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.046 kDa
Sequence
MFRIGQGFDVHQLTEGRPLIIGGIEIPYEKGLLGHSDADVLLHTVADACLGAAGEGDIGKHFPDTDPEFKDADSFKLLQHVWNIVKEKGYVLGNIDCTIIAQKPKMAPHIDAMRKRIAEGLEADVSQVNVKATTTEKLGFTGRAEGIAAQATVLIQKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Brachyspira hyodysenteriae (strain ATCC 49526 / WA1)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.489 kDa
Sequence
MRIGYGYDSHAFAENRKLILSGIEIPYELGLKGHSDADAVIHALIDSILGALALGDIGSHFPDNDSKYKGISSIVLLEKTVSIMEEKNYEISNTDITIILEKPKLRNYIDTMRENLSKILKTDIENVSIKAKTNEKMDSIGRGEGIAVHCVSLLKKTK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacillus sp. (strain WCH70)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.161 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGVRIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGKHFPDTDECYKDADSALLLKQVWELVKQQGYELANLDCTIIAQKPKMAPHIEQMKENIANLLEGELSQVNVKATTTEKLGFTGREEGIAAQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain 86-028NP)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.179 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDILCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain PittEE)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain PittGG)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
Similarity
Belongs to the IspF family.
Mass
17.194 kDa
Sequence
MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus anthracis (strain A0248)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus anthracis (strain CDC 684 / NRRL 3495)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus thuringiensis (strain Al Hakam)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus anthracis
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain AH820)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.205 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGVTIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain G9842)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain 03BB102)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain B4264)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.147 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWGFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain AH187)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.245 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain Q1)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus cereus (strain ZK / E33L)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.219 kDa
Sequence
MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Lysinibacillus sphaericus (strain C3-41)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.299 kDa
Sequence
MFRIGQGFDVHAFEEGRPLIIGGITIPHEKGLVGHSDADVLLHTVTDAALGAIGEGDIGRHFPDTDPAFKDADSAKLLEYIWKIVEDKGYILGNVDCTIMAQRPKMAPYIEQMQNRIAELLHAEPSQVNVKATTTERLGFTGREEGIAAMATILLMKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.943 kDa
Sequence
MFRIGQGYDAHRFKEGDHIVLCGVKIPFGRGFAAHSDGDVALHALCDALLGAAALGDIGRHFPDTDARYKGIDSRVLLREVRQRIASLGYTVGNVDVTVVAQAPRLAAHIQAMRENLAQDLEIPPDCVNVKATTTEGMGFEGRGEGISAHAVALLARR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.837 kDa
Sequence
MIRIGHGFDVHRFGGEGPIIIGGVKIPYEQGLIAHSDGDVALHALSDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKAQGYVLGNADVTIIAQAPKMAPYIQAMCAAIAEDLETDLGNINVKATTTEKLGFTGRKEGIACEAVVLLRKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio cholerae serotype O1 (strain M66-2)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.837 kDa
Sequence
MIRIGHGFDVHRFGGEGPIIIGGVKIPYEQGLIAHSDGDVALHALSDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKAQGYVLGNADVTIIAQAPKMAPYIQAMCAAIAEDLETDLGNINVKATTTEKLGFTGRKEGIACEAVVLLRKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.949 kDa
Sequence
MIRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHALTDALLGAIAAGDIGRHFPDTDDKWKGANSRELLKDVYRRVKEQGYRLGNADVTIMAQAPKMAPHIDAMCAAIAEDLETDISNINVKATTTERLGFTGRKEGIATEAVVLLFKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio vulnificus (strain CMCP6)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.085 kDa
Sequence
MIRIGHGFDVHKFGGEGPVIIGGVAVPYEQGLIAHSDGDVALHALSDALLGAIAAGDIGRHFPDTDDKWKGVDSRELLKDVYRRVKEQGYKLGNADVTIIAQAPKMAPYIDAMREAIAHDLETDIRNINVKATTTERLGFTGRKEGIATEAVVLLIKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio vulnificus (strain YJ016)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.056 kDa
Sequence
MIRIGHGFDVHKFGGEGPVIIGGVAVPYEQGLIAHSDGDVALHALSDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKEQGYKLGNADVTIIAQAPKMAPYIDAMREAIAHDLETDIRNINVKATTTERLGFTGRKEGIATEAVVLLIKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium tetani (strain Massachusetts / E88)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.457 kDa
Sequence
MRVGIGYDVHKLVDGRDLIIGGEKIPFEKGLLGHSDADVLCHAIGDSILGAAALGDIGRHFPDTDNRYKGYSSLKLLEEIKRIINEKGYYITNIDSTIIAQKPKMLAYINNMRKNISKVLDISIEDINIKATTEEELGFTGKQLGIKAQSICLLNKNI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Rhodococcus opacus (strain B4)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.173 kDa
Sequence
MRVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVFGTGRPEWSGVSGAAMLAEVRRLLEQDDFGVANAAVQVIGNRPKIGPRRNEAQKVLSDILGAPVSVSATTTDGLGLTGRGEGIAAMATALVIPDRSAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.213 kDa
Sequence
MLRVGIGYDVHALVAGRPLILAGIDIPHEKGLLGHSDADVLTHTLMDALLGALALGDLGKHFPDTDERYRGISSMKLLEQVMKLLEERGYAIGNIDCIIAAQRPKLAPYIPQMRENLARALKTDLENVSVKATTTERLGFEGREEGISSQAIVCLVKV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Desulfitobacterium hafniense (strain Y51)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.213 kDa
Sequence
MLRVGIGYDVHALVAGRPLILAGIDIPHEKGLLGHSDADVLTHTLMDALLGALALGDLGKHFPDTDERYRGISSMKLLEQVMKLLEERGYAIGNIDCIIAAQRPKLAPYIPQMRENLARALKTDLENVSVKATTTERLGFEGREEGISSQAIVCLVKV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.013 kDa
Sequence
MFRIGQGFDVHQLVEGRPLIIGGVTIPYEKGLLGHSDADVLLHAVADACLGAIGAGDIGRHFPDTDPRFKDADSAELLAHVWALARQEGYRLVNADCTIIAQKPKLAPYIEEMRAVIARLLEAERSQVNVKATTTEKLGFTGRGEGIAAQAVVLLQKS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.837 kDa
Sequence
MIRIGHGFDVHRFGGEGPIIIGGVKIPYEQGLIAHSDGDVALHALSDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKAQGYVLGNADVTIIAQAPKMAPYIQAMCAAIAEDLETDLGNINVKATTTEKLGFTGRKEGIACEAVVLLRKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.95 kDa
Sequence
MIRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHALTDALLGAIAAGDIGRHFPDTDDKWKGADSRELLKDVYRRVKEQGYRLGNADVTIMAQAPKMAPHIDAMCAAIAEDLETDISNINVKATTTERLGFTGRKEGIATEAVVLLFKQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.635 kDa
Sequence
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRECAARVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGDGIEAQAAALLVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobium phaeobacteroides (strain DSM 266)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.918 kDa
Sequence
MRTGIGIDVHPFAEGRKLVIGGVEIPSAKGLDGHSDADVLLHAVSDALLGAAALGDIGLHFPNTSQEFKDIDSMILLKHVKKLLDKEGFRIVNIDAMLLLEAPKIASYINEMRKNIARCLGLELNAVSVKATTNEKLGYIGREEGAAAHAVCLIQVKP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.993 kDa
Sequence
MRIGHGFDAHRFGSTGKLILGGVEIPHEQGLIAHSDGDVVIHALCDALLGGAALGDIGRHFPDTSAEFKNADSQKLLHRVMVLLKEHGFKVSNGDMTIIAQIPKLAPYLPAMRETLALALGLPLQRFNIKATTTERMGYIGRAEGIAAHAVVLLLEEQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pasteurella multocida (strain Pm70)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.555 kDa
Sequence
MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLLAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKGADSRGLLREAYTQVQAKGYKVGNVDVTIIAQAPKMRPHIDAMRAAIAEDLACDIEQVNVKATTSERLGFTGRGEGIACEAVALVVKS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.789 kDa
Sequence
MRIGHGYDVHKLVEGRKLIMGGVDIPWEKGLLGHSDADVLLHAIADAILGALGEGDIGKHFPDTDPAYKGADSLKLLEHVANLAIAKGYCLGNLDATIIAQRPKMAPHIPAMRENIARVLRSTVDRVNVKATTEEGLSFTGRGEGISAHAVVLMIGKG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Sodalis glossinidius (strain morsitans)
Length
158 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.739 kDa
Sequence
MRIGHGFDVHKFGGEGPLIIGGVRIPYPQGLLAHSDGDVALHTATDALLGAAALGDIGKLFPDTDSAFKGADSRALLREAWRRIAAKGYRLGNLDITLIAQVPKMALHIPQMRVNIAEDLGCHMDDVNVKATTTEQLGFTGRGEGIACEAVALLVRTS

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.924 kDa
Sequence
MRIGIGIDVHQFAEGRKLIIGGVEVPSPIGLLGHSDADVLLHAISDALLGAAALGDIGKHFPDTSPDYKDADSMELLRHVCKLLEQEGYKPVNVDTMLLLEKPKIAPYIDQMRRNIARCLGLEINAVSVKATTNEKLGYVGRQEGACAHAVCLIENA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Alaska E43 / Type E3)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.114 kDa
Sequence
MRVGLGYDVHKLVENRKLILGGVEIPYEKGLLGHSDADVLLHAIMDSLLGACALGDIGRHFPDTDNKFKGISSIKLLEEVNKLIIKNGYIINNIDSVIIAQKPKLAPYIENMRVNISNALNIEIDKINIKATTEEGLGFTGSMLGISSQSICSVIKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.13 kDa
Sequence
MRVGLGYDVHKLVENRKLILGGVEIPYEKGLLGHSDADVLLHAIMDSLLGACALGDIGRHFPDTDNKFKGISSIKLLEEVNKLIIKNRYIINNIDSVIIAQKPKLAPYIDTMTENISNALNIKIDQINIKATTEEGLGFTGGMLGISSQSICSVIKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas entomophila (strain L48)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.843 kDa
Sequence
MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVGIVDNKGWKVGNVDATIVAQAPKMAPHIETMRQQIAADLQVELDQVNVKATTEEKLGFTGREEGIAVHAVALLLPA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.928 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHHFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVALIHAKGWKIGNVDNTIVAQAPKMAPHIETMRALIAEDLQVELDQVNVKATTTEKLGFVGREEGIAVHSVALLQRP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas fluorescens (strain SBW25)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.752 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHHHGLLAHSDGDVVLHALSDALLGAAALGDIGKHFPDTDPTFKGADSRVLLRHVVGLIHAKGWKVGNVDNTIVAQAPKMAPHIESMRALIAADLQIELDQVNVKATTTEKLGFTGREEGIAVHSVALLLRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas mendocina (strain ymp)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.724 kDa
Sequence
MRIGHGYDVHRFGEGDFITLGGVRIPHKFGLVAHSDGDVLLHALSDALLGAVALGDIGKHFPDTDPTFKGADSRALLRHVMSLVRGKGYAVGNVDATIIAQAPKMAPHIQSMRERIAEDLGVELDQVNVKATTTEKLGFTGREEGIAVHAVALLVKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.816 kDa
Sequence
MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRALLRHVVGIVKAKGWKVGNVDATIVAQAPKMAPHIETMRQLIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHSVALLLPA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.737 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVSLIHAKGWKVGNVDNTIVAQAPKMAPHIESMRALIAADLQVELDQVNVKATTTEKLGFVGREEGIAVHSVALLLRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas putida (strain GB-1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.844 kDa
Sequence
MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRALLRHVVGIVRAKGWKVGNVDATIVAQAPKMAPHIETMRQLIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHSVALLLPA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.816 kDa
Sequence
MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRALLRHVVGIVKAKGWKVGNVDATIVAQAPKMAPHIETMRQLIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHSVALLLPA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas putida (strain W619)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.873 kDa
Sequence
MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAGLGDIGKHFPDTDPQFKGADSRVLLRHVVGIVQAKGWKVGNVDATIVAQAPKMSPHIETMRQRIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHAVALLLPA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.749 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVLKQIHGKGWKVGNVDATIVAQAPKMAPHIDAMRALIAEDLLVELDQVNVKATTTEKLGFTGREEGIAVHAVALLLRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.706 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVLTLIHGKGWKVGNVDATIVAQAPKMAPHIDAMRALIAEDLQVEPDQVNVKATTTEKLGFTGREEGIAVHAVALLLRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas stutzeri (strain A1501)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.772 kDa
Sequence
MRIGHGYDVHRFGEGDHITLGGVRIPHRFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRALLRHVLAQVQAKGYVVGNVDATIVAQAPKMAPHIERMRALIAADLQVELDQVNVKATTTEKLGFTGREEGIAVHAVALLVRP

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Alkaliphilus oremlandii (strain OhILAs)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.617 kDa
Sequence
MRVGIGYDVHKLVADRKLIIGGVHIPYEKGLLGHSDADVLLHAIKDAILGAAALGDIGKHFPDTDERYKGANSLELLKEVSNLIKSKGYKIHNLDATIIAQKPKMASHIEQMRANIAAAINVDMDSVNVKATTTEGLGFVGVGEGIAANAIASIIKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.751 kDa
Sequence
MIRVGQGFDVHQFAEGRLLIIGGVEIPYEKGLLGHSDADVLLHTIADAALGAIGEGDIGKHFPDTDPHFKDADSAKLLSAVWELVKEKGYTLGNVDCTIIAQKPKMAPHIPAMRARIAELLEAEEAQVNVKATTTETLGFTGRGEGIASQAVILLVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Blochmannia pennsylvanicus (strain BPEN)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.207 kDa
Sequence
MLRIGYGFDVHQFGGCRPLTIGGVSIPCMKGIKAHSDGDVMMHSLIDALLGAACCGDIGSMFPDTDAKYNNIDSRKLLRIAWEKITMQGFLLENIDITVILQIPKINTYIYQMKHHLSQDLNCSVTSINIKATTTDTLGYIGRSEGIACIAVVLLTR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter uraniireducens (strain Rf4)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.825 kDa
Sequence
MRIGHGYDVHKLVENRKLILGGVDIPYERGLLGHSDADVLLHAISDAILGAIGEGDIGKHFPDTDPAYKGADSIKLLMHVMALAVGKGYAIGNLDATIVAQRPKLAPHIPQMRENIARALKADADRINVKATTTEELGFAGRGEGIAAYTVVLLERK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.751 kDa
Sequence
MIRVGQGFDVHQFAEGRLLIIGGVEIPYEKGLLGHSDADVLLHTIADAALGAIGEGDIGKHFPDTDPHFKDADSAKLLSAVWELVKEKGYTLGNVDCTIIAQKPKMAPHIPAMRARIAELLEAEEAQVNVKATTTETLGFTGRGEGIASQAVILLVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Blochmannia pennsylvanicus (strain BPEN)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.207 kDa
Sequence
MLRIGYGFDVHQFGGCRPLTIGGVSIPCMKGIKAHSDGDVMMHSLIDALLGAACCGDIGSMFPDTDAKYNNIDSRKLLRIAWEKITMQGFLLENIDITVILQIPKINTYIYQMKHHLSQDLNCSVTSINIKATTTDTLGYIGRSEGIACIAVVLLTR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter uraniireducens (strain Rf4)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.825 kDa
Sequence
MRIGHGYDVHKLVENRKLILGGVDIPYERGLLGHSDADVLLHAISDAILGAIGEGDIGKHFPDTDPAYKGADSIKLLMHVMALAVGKGYAIGNLDATIVAQRPKLAPHIPQMRENIARALKADADRINVKATTTEELGFAGRGEGIAAYTVVLLERK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.995 kDa
Sequence
MRIGHGYDVHRFAEGDFVTLGGVRIPHRFGLLAHSDGDVLLHALCDALLGAAALGDIGRHFPDTDPRFKGVDSRVLLRHVVALVREKGWRVGNVDATIVAQAPKMAPHIERMRLSIAEDLQVGVEQVNVKATTTEKLGFTGREEGIAVHAVALLLAL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.228 kDa
Sequence
MIRIGQGYDVHKLDYDRELIIGGIKIPYEKGLLGHSDADVLLHAITDAIIGAIGALDIGHFFPDTDMAYKDADSAELLAEIWRQVEAEGFKLGNLDATIIAEKPKMAPYVELMKRRIAELLHAEPSQVNVKATTTEKLGFTGREEGIASLAVVLLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Listeria monocytogenes serotype 4b (strain CLIP80459)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.073 kDa
Sequence
MIRIGQGYDVHKLAYDRELIVGGIKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMAFKDADSAELLEEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGRKEGIASLAVVLLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Listeria monocytogenes serotype 4b (strain F2365)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.074 kDa
Sequence
MIRIGQGYDVHKLAYDRELIVGGIKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMAFKDADSAELLEEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGREEGIASLAVVLLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Listeria monocytogenes serotype 4a (strain HCC23)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.016 kDa
Sequence
MIRIGQGYDVHKLAYDRELIVGGIKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMAFKDADSAELLAEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGREEGIASLAVVLLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.03 kDa
Sequence
MIRIGQGYDVHKLAYDRDLIIGGVKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMVFKDADSAELLAEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGREEGIASLAVVLLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Wigglesworthia glossinidia brevipalpis
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.252 kDa
Sequence
MRVGHGFDIHKFGKIYKPLILGGVHIPYCKGVVSHSDGDVIIHSIIDSLLGASSLGDIGILFPNNDIKYKNINSCILLQVVWNCIKKKYKIGNIDVTLFLEYPKISSYTNKICLCISNCLKCKTDVINIKSKTMEGLGEIGKKKGIASEAVSVLLEI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium novyi (strain NT)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.029 kDa
Sequence
MRIGMGYDVHKLCENRKLILGGIEIPYELGLLGHSDADVLIHAIMDSLLGAAALGDIGKHFPDTDNKYKGISSMLLLKEVGKLLNENSYEIINIDATIIAQKPKMAPYIKDMIKNIASALCINENQVNIKATTEEGLGFTGEGLGISSQSICLINEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.633 kDa
Sequence
MRIGNGYDVHRLAPGQKLVLGGVEIPFECGLIGWSDADVLTHAIMDSLLGAAALGDIGLYFPPGDPKFKGISSLKLLEQVTALLAEKGFGIINVDSVIVAEEPKLRGHVDTMRKHLAKAMGIDPGRVGIKASTSEQLGFVGREEGMAAWAVALVDEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Dehalococcoides mccartyi (strain CBDB1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.733 kDa
Sequence
MRIGNGYDVHRLAPGQKLVLGGVEIPFECGLIGWSDADVLTHAIMDSLLGAAALGDIGLYFPPGDPKYKGISSLKLLEQVTDLLAKKGFGIINVDSVIVAEEPKLRGHIDTMRKHLAKAMGIDPGRVGIKASTSEQLGFVGRQEGMVAWAVALVDEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Desulfotomaculum reducens (strain MI-1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.837 kDa
Sequence
MRVGIGYDVHKLVAERQLVLGGVVIPYEFGLLGHSDADVLIHAIMDALLGAAALGDIGRHFPDNEPRYKGISSMKLLEEVREKLAVKGYSVNNLDAVVVAQAPKLAPYIQAMQQNIARTLQVDLDSVNIKATTTEHLGFAGRGEGIGAYAVCTLQQG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Salinibacter ruber (strain DSM 13855 / M31)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.741 kDa
Sequence
MRIGFGYDVHRLVEGRPLILGGVQVPHDRGLAGHSDADVLLHAVADALLGAAALGDLGAHFPDTDAKWKDADSQALLRRVVERVQHAGYAPHNVDATVLLERPKLRPHVDEMRTNIARALSFPRDAVSVKATTTEGIGFVGREEGVAAQAACTIQSA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Serratia proteamaculans (strain 568)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.809 kDa
Sequence
MRIGHGFDVHKFGGEGPLVIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRVLLREAWKRIRAKGYRLGNLDITIIAQAPKMAPHIPQMRVFLAEDLQCHMDDVNVKATTTEQLGFTGRGEGIACEAVALLIKE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.747 kDa
Sequence
MRIGHGYDVHRLVEDRKLIMGGVDIPWEKGLLGHSDADVLLHAIADALLGALAMGDIGKHFPDTDPAFKGADSMKLLEHVVGLIRTQGYAVGNLDATIIAQRPKMAPHIQAMRENVARACGVEVDRINVKATTEEGLGFTGTGEGISAHAVVLLIPQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.89 kDa
Sequence
MRIGHGYDVHCLVEGRKLILGGVDVPYERGLLGHSDADVLLHAIADAILGALALGDIGKHFPDTDPQFKGADSRKLLRHVMALAGQKGYVLGNVDATIVAQRPKLAPFIPEMRANLAEDLIAEIDRINVKATTTEQLGFAGRGEGIAAYAVVLMERR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.92 kDa
Sequence
MRIGHGYDVHRLVAGRKLIVGGVDIPHELGLLGHSDADVLLHAISDAILGALALGDIGKHFPDTDPRYKGADSRALLRHVMELATRKGFHLGNLDATIVAQRPKMAPHIPLMREHIAADLMADPDRVNVKATTTEELGFAGRGEGIAAYAVVLMEEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechococcus sp. (strain JA-3-3Ab)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.049 kDa
Sequence
MRIGQGYDIHRLVEGRPLILGGIRIPYEKGLLGHSDADVLTHAIMDALLGAAALRDIGYYFPPEDERWKGADSILLLQQVVQLVGQEGWRIANVDSVVVAEQPKLKPHIPAIQARLAEAMQLSPKQVGVKATTNEKLGPVGQGEAMAAFAVVLLLER

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Synechococcus sp. (strain JA-2-3B'a(2-13))
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.049 kDa
Sequence
MRIGQGYDIHRLVEGRPLILGGIRIPYEKGLLGHSDADVLTHAIMDALLGAAALRDIGYYFPPEDERWKGADSILLLQQVVQLVGQEGWRIANVDSVVVAEQPKLKPHIPAIQARLAEAMQLSPKQVGVKATTNEKLGPVGQGEAMAAFAVVLLLER

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.96 kDa
Sequence
MRVGYGYDVHRLQEGRRLVLGGVEIPHMQGLLGHSDADVLLHAICDALLGAAALGDIGQHFPDSDSQYKDINSLLLLKEVAGILQRAGWRVINVDSTVVAQEPRLAPHIKQMRQNIARVLAIESEQVSVKATTTEGLGFAGRQQGISAHAVVLIEQA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.205 kDa
Sequence
MFKVGIGYDVHRFVEGRKLILGGVEIPFEKGLLGHSDADVLVHAIIDAILGAMGENDIGRLFPDSSPNYKDISSLVLLKEVAKLLEEKNMKIVNIDSTVVSQRPKISPYTNEMKNKIADCLKIESTQVNIKGKTTEGLGFEGREEGISAYAVVLICE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.289 kDa
Sequence
MFKVGFGFDVHRFSEDRKLILGGVEIPFEKGLLGHSDADVLIHAIIDAILGAMGENDIGRLFPDTDMKYKDISSIVLLKEVSKLLKNKGMSIINIDTTIVAQKPKISPYTDEMKTNIAKALNIEKTQVNIKGKTTEGLGFEGREEGVSAYAIVLLHE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobium chlorochromatii (strain CaD3)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.504 kDa
Sequence
MRIGIGIDVHPFAAGRKLVIGGVYIPGHDGLDGHSDADVLLHAISDALLGAAALGDIGLHFPNTSAEFKDIDSMILLKHVGKLLAEHGYAPVNVDAMLLLEAPKIAPYIQQMRQNIADALGLQVGDVAVKATTNEKLGYIGRKEGAEAHAVCLIQGK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobium luteolum (strain DSM 273 / 2530)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.737 kDa
Sequence
MRIGIGIDVHPFAEGRKLIVGGVDIPSPKGLEGHSDADVLLHAVSDALLGAAALGDIGLHFPNTSAEYKDIDSMILLKHVGRLLTKNGYRTVNVDAMLLLEAPKIAPYVADMRRNIARCLDIDTSLVSVKATTNEKLGYIGREEGAAAHAVCIIETL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobaculum parvum (strain NCIB 8327)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.05 kDa
Sequence
MRIGIGIDVHQFSEDRKLIVGGVEVPSPVGLLGHSDADVLLHAISDALLGAAALGDIGKHFPDTSPDYKDADSMELLKHVGKLLEQEGYKPVNIDTMLLLEKPKIAPYIEQMRRNIASCLDMDMNDVSVKATTNEKLGYVGRQEGACAHAVCLIEKK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chlorobium phaeovibrioides (strain DSM 265 / 1930)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.829 kDa
Sequence
MRIGIGIDVHSFKEGRKLIVGGVDIPSPKGLDGHSDADVLLHAVSDALLGAAALGDIGLHFPDTSPEFKDIDSMILLKHVGKLLEKNGWRTVNVDAMLLLEAPKIAPFVVDMRKNIARCLQIETDLVSVKATTNEKLGYIGREEGAAAHAVCIIEKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Chloroherpeton thalassium (strain ATCC 35110 / GB-78)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.926 kDa
Sequence
MRIGIGIDIHQLVEGRKLIIGGVEIPYEKGLKGHSDADVLLHAISDALLGAAALGDIGKHFPDTDPAYKGIDSQLLLKHVRKLLETHGYKPVNVDSMLLLEKPKIAPHVQKMRENIAACLEVDVDAISVKATTNEKIGYVGRGEGALAHAVCLIEKI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.925 kDa
Sequence
MRIGIGIDVHPFAEGRKLVIGGVHIPGHNGLDGHSDADVLLHAVSDALLGAAALGDIGLHFPNTSQEFKDIDSMILLKQVRKLLEKHGYQTVNIDAMLLLEEPKIAPYITGMRKNIARCLDIEIGMVSVKATTNEKLGYIGREEGAAAHAVCIIRSL

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Edwardsiella ictaluri (strain 93-146)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.603 kDa
Sequence
MRIGHGFDVHRFGGEGPLIIGGVRIAHPQGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAYKGADSRALLREAYRSIRARGYRLGNLDITLIAQAPKMAPHIPQMRVFLAEDLQCPIDDVNVKATTTEKLGFTGRGEGIACAAVALLIKE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.692 kDa
Sequence
MIRIGQGFDVHQLVPQRPLIIGGVTLPYEKGLLGHSDADVLTHAIIDAILGAAGLGDIGQLFPETDPQFKNANSVNLLKKVNEKVGRSGFTIGNIDCTILAEEPKMSPYLAEMKKNLAASCHLAVTQVNIKATTMETMGFVGKKEGIGAIAVALLEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.619 kDa
Sequence
MRIGHGFDVHAFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDEAYKGADSRELLREALRQIAQKGYRVGNVDVTIIAQAPKMLPHAPQMRINIAEDLGIHMDEVNVKATTTEKLGFTGRGEGIACEAVALLIKA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.571 kDa
Sequence
MLIGFGYDVHRLVPGRPLVLGGVEIPSKRGLEGHSDADVALHALMDALLGAAGLGDIGTHFPPTDPAWAGANSLDLLRRVVGLLAEEGYRPVNCDITVVAERPKIGPYVPAMRERIGAVLGVEPRRVSIKATTNEQMGFVGREEGIAAYAVALIAGR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.935 kDa
Sequence
MRIGHGFDVHKFGGEGPIIIGGVRIPYEQGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGVDSRKLLREAYSRIREKGYRIGNLDITIIAQAPKMLPHIPQMRVNLAEDLQCHIDDINVKATTTEKLGFVGRKEGIACEAVALLVKE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Photobacterium profundum (strain SS9)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.664 kDa
Sequence
MRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHAVCDALLGAIGAGDIGRHFPDTDAEWKGADSRFLLRDVYSKVKDKGYRLGNLDVTIIAQAPKMAPYIDAMCQAIAEDLETDIGNVNVKATTSERLGFTGRKEGIACEAVVLINAQ

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.053 kDa
Sequence
MRVGIGIDVHQFVENRKLIIGGIEIPHTMGLKGHSDADVLLHAISDALLGAAALGDIGKHFPDTSPDFKDIDSRILLRHVGKLIADEGYTIVNIDSMLLMERPKVAPYIVAMRESIAECLDIETSRVSVKATTNEKLGYIGRQEGAAAHAVCLIEEK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.764 kDa
Sequence
MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVLKQIHGKGWKVGNVDATIVAQAPKMAPHIDAMRALIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHAVALLLRA

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.692 kDa
Sequence
MRIGHGYDVHRFGEGDYITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVALDQVNVKATTTERLGFTGREEGIAVHAVALLMAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas aeruginosa (strain LESB58)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.662 kDa
Sequence
MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.636 kDa
Sequence
MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGSIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
157 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.662 kDa
Sequence
MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Aquifex aeolicus (strain VF5)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.307 kDa
Sequence
MELRIGFGFDSHEFVEGKLLILGGVEIEKDYGLKGHSDGDALLHAITDAILGALGERDIGEIFKDTDPRWKNAPSRIFLEKALEVMSEKGFNISNIDCVIVADRPKIAPHKERIKESLSKLLGIPKERISLKGKRREGFCEGNGLVCMCTVLLVKM

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Hydrogenobaculum sp. (strain Y04AAS1)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.372 kDa
Sequence
MYRIGIGQDAHYFEKGKKLYLGGEEFDIGYGLKGHSDGDALLHAITDAILGALAKTDIGTLFPDKSKENKNRNSVDFLNKALEIMYDMDYSIVNLDCNIIADKPNISSVRDKIIESLSRLLSIPKDNISIKAKTKEGYNKEDSLEVVCIALLQKMI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Hydrogenobaculum sp. (strain Y04AAS1)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.372 kDa
Sequence
MYRIGIGQDAHYFEKGKKLYLGGEEFDIGYGLKGHSDGDALLHAITDAILGALAKTDIGTLFPDKSKENKNRNSVDFLNKALEIMYDMDYSIVNLDCNIIADKPNISSVRDKIIESLSRLLSIPKDNISIKAKTKEGYNKEDSLEVVCIALLQKMI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.106 kDa
Sequence
MYRVGIGFDAHPLEANKKGLYLGGVKVSEEYSSIGHSDGDALIHAIVDAILGATNAGNIGIWFPENEENRGRRSTEFLEIIRKKILAGKYEILNIDSVIIIDKVRMNPHIENIRLKLARILGISKGNINVKPKSGNTLYGNSVSVYAVCMLKKVGT

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.866 kDa
Sequence
MRIGMGYDVHKLVENRDLILGGVKIPYEKGLLGHSDADVLLHAIMDSLLGAAALGDIGKHFPDTDPKYKGADSIKLLEFVGELLNKNNYKISNIDATIIAQRPKMAPHIPTMRENIAKALNIDLDQINVKATTEEGLGFTGSGEGISSQSICLLVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium perfringens (strain 13 / Type A)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.866 kDa
Sequence
MRIGMGYDVHKLVENRDLILGGVKIPYEKGLLGHSDADVLLHAIMDSLLGAAALGDIGKHFPDTDPKYKGADSIKLLEFVGELLNKNNYKISNIDATIIAQRPKMAPHIPTMRENIAKALNIDLDQINVKATTEEGLGFTGSGEGISSQSICLLVK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium perfringens (strain SM101 / Type A)
Length
156 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.92 kDa
Sequence
MRIGMGYDVHKLVENRDLILGGVKIPYEKGLLGHSDADVLLHAIMDSLLGAAALGDIGKYFPDTDPKYKGADSIKLLEFVGELLNKNNYKISNIDATIIAQRPKMAPHIPTMRENIAKALNIDLDKINVKATTEEGLGFTGTGEGISSQSICLLIK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.592 kDa
Sequence
MRVGIGYDVHKLVENRKLILGGVEIQYSKGLLGHSDADVLVHAIIDSILGAAGLGDIGKLFPDSDNKYKGISSLKLLKEVNALIKDKGYKIGNIDSTIIAQKPKISPYIEDIKKSLCNVLDIDLGSINIKATTEEGLGFTGRGEGISSQSICLLI

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain ATCC 19397 / Type A)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.863 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain 657 / Type Ba4)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.862 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLN

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.863 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Kyoto / Type A2)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.864 kDa
Sequence
MRIGLGYDVHKLVEDRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Okra / Type B1)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.862 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHINAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.863 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Clostridium botulinum (strain Loch Maree / Type A3)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.863 kDa
Sequence
MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
17.218 kDa
Sequence
MNIRIGQGFDSHKLKTKKNSRVFLGGIPVRTDQQLIANSDGDVVLHALSDAVLGCGSFGDIGMYFDENDLSNKGLDSKTILNYCLKLIKKLKLEFVNIDLTIFAQDIRIDPIRFEIKSSLMKLTGCNSVNVKAKSYEEPKNEIACSCVVLMNTNK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Koribacter versatilis (strain Ellin345)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.321 kDa
Sequence
MIRVGLGFDSHEFREGIPLRIGGLTIPHTHGLSGHSDGDVLLHAITDALLGAVAAGDIGAFFPPSDPKWKGANSVVFIEEAMRHIETAGYRVGNVDCSLVLNAPKIGPHAKAIQESVAKLLKIEPTAVGIKAKTPEGLNLDGTALAHVVVLLEKR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.499 kDa
Sequence
MRIGQGVDVHAFGDGDKIVIGGVVIPYERGLVAHSDGDVLLHALCDALLGAAALGDIGKHFPDTDSAYKNACSRTLLRMVYSKLKAKGYSLVNADMTIVAQAPKMAPHISDMRAKIAEDLDTHIDNINVKATTTEQLGFNGRKEGITALATVLIK

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Desulfatibacillum aliphaticivorans
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.477 kDa
Sequence
MRVGYGYDVHRLVDGRPLVLGGVTIPFDKGLKGHSDADVLLHAVCDALLGAAGLGDIGMHFPDKDPKYKNIASTRLLEETGRKIAQEGYKIVNLDATLVAEAPKIGPYRQEMVSVIAKCLGLENRQVNVKATTTEGLGITGRGEGMAATCVACLE

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Nocardia farcinica (strain IFM 10152)
Length
155 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.722 kDa
Sequence
MRVGIGSDVHPIEPGRPCWMAGLLFEGEDGCSGHSDGDVAAHALCDALLSAAGLGDVGAVFGTGRPEWADVSGAAMLTEVRRLLGEAGFEVVNAAVQVIGNRPKIGPRRAEAQRVLGDLLDAPVSVSGTTTDGLGLTGRGEGIAAVATALLRPRV

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermobifida fusca (strain YX)
Length
154 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
15.727 kDa
Sequence
MVGVGTDVHPFQTGRPLFLAGLEWPDEVGLSGHSDGDVAAHAACDALFSACALGDLGSQFGTSDPRWRGASGVALLTEAAQRVRAAGYEIGNIAIQIIGNRPKFAPRRHEAEKVLSAAVGAPVSCAATTTDGLGFTGRGEGIAAVATALCVRVR

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
152 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.532 kDa
Sequence
MRIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAALHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREALRLVEARGARLLQASLVLTLDRPKLGPHRKALVDSLARLLRLPQDRIGLTFKTSEGLAPSHVQARAVVLLDG

Gene
ispF
Protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
152 amino acids
Function
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
Similarity
Belongs to the IspF family.
Mass
16.52 kDa
Sequence
MRIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAALHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREALRLVEARGAKLLQASLVLTLDRPKLGPHRKALVDSLSRLLRLPQDRIGLTFKTSEGLAPSHVQARAVVLLDG