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ihh

Gene
IHH
Protein
Indian hedgehog protein
Organism
Homo sapiens
Length
411 amino acids
Function
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
Similarity
Belongs to the hedgehog family.
Mass
45.251 kDa
Sequence
MSPARLRPRLHFCLVLLLLLVVPAAWGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRLRAFQVIETQDPPRRLALTPAHLLFTADNHTEPAARFRATFASHVQPGQYVLVAGVPGLQPARVAAVSTHVALGAYAPLTKHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFHSLAWGSWTPGEGVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS

Gene
Ihh
Protein
Indian hedgehog protein
Organism
Mus musculus
Length
411 amino acids
Function
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
Similarity
Belongs to the hedgehog family.
Mass
45.485 kDa
Sequence
MSPAWLRPRLRFCLFLLLLLLVPAARGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLENGERVALSAVKPGDRVLAMGEDGTPTFSDVLIFLDREPNRLRAFQVIETQDPPRRLALTPAHLLFIADNHTEPAAHFRATFASHVQPGQYVLVSGVPGLQPARVAAVSTHVALGSYAPLTRHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFPSLAWGSWTPSEGVHWYPQMLYRLGRLLLEESTFHPLGMSGAGS

Gene
ihh
Protein
Indian hedgehog protein
Organism
Xenopus laevis
Length
409 amino acids
Function
Signal involved in the early induction and patterning of anterodorsal ectoderm, nervous system and somites. Induces ectopic cement gland formation in embryos.
Similarity
Belongs to the hedgehog family.
Mass
45.591 kDa
Sequence
MQLPKVVLLLCAAALLLSGAVRGCGPGRVVGRRRRPTKLSPLSYKQFSPNVPEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEEITGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDRNKYGMLARLAVEAGFDWVYYESKAHIHCSVKSEHSAAAKTGGCFPGEALATLESGEKIPVSQLSPGLRVLAMDNSGRPTYSDFLSFLDHSPKEEHMFQVIKTQDPHRRLFLTPAHLIFVSDNYSTPASEFQAVFASSVRPGQYILVSNVVGLIPAKVRSVNTQTNYGAYAPLTQHGTLVVDDVVVSCFALVQKQRLAQIVYWPLRVLYNLGIIAGTQPSQQMGIHWYSKALYHLGRLILHGNEFHPLGIVQLES

Gene
IHH
Protein
Indian hedgehog protein
Organism
Gallus gallus
Length
408 amino acids
Function
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
Similarity
Belongs to the hedgehog family.
Mass
44.829 kDa
Sequence
MKPARLLLLLSGCALLLAPAVRCCGPGRVVGSRRRPPRKLIPLAYKQFSPNVPEKTLGASGRYEGKIARNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGMLARLAVEAGFDWVYYESKAHIHCSVKSEHSAAAKTGGCFPGRALATLENGARTPLWALRPGQRVLAMDGAGRPTYSDFLAFLDKEPRALTAFHVIETRQPPRRLALTPTHLLFVADNASAPAAQFRPTFASHVQPGHFVLVAVGSGGLQPAEVVGVRGRTDVGAYAPLTRHGTLVVDDVVASCFALVREQQLAQMAFWPLRLYHSLLGGPGVQGDGVHWYSGLLYRLGRMLLPPDSFHPLGAPRAES

Gene
ihh
Protein
Indian hedgehog protein
Organism
Carassius auratus
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Danio albolineatus pulcher
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Danio aff. tweediei
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Danio kerri
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Devario devario
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Devario malabaricus
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.714 kDa
Fragment
single
Sequence
VMNLWPGIRLRVTEGWDEDGHHSEESLHYEGRAVDITTEDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Devario pathirana
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.672 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAAF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Puntigrus tetrazona
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Rasbora elegans
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.658 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Rasbora paviana
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.688 kDa
Fragment
single
Sequence
VMNLWPGVRLRVMEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF

Gene
ihh
Protein
Indian hedgehog protein
Organism
Trigonostigma heteromorpha
Length
58 amino acids
Function
Intercellular signal essential for a variety of patterning events during development.
Similarity
Belongs to the hedgehog family.
Mass
6.628 kDa
Fragment
single
Sequence
VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITASDRDRNKYAMLARLAVEAGF