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igf2

Gene
igf2
Protein
Insulin-like growth factor II
Organism
Oncorhynchus mykiss
Length
214 amino acids
Function
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for integrin which is required for IGF2 signaling.
Similarity
Belongs to the insulin family.
Mass
24.637 kDa
Sequence
METQKRHEYHSVCHTCRRTENTRMKVKMMSSSNRVLVIALALTLYIVEVASAETLCGGELVDALQFVCEDRGFYFSRPTSRSNSRRSQNRGIVEECCFRSCDLNLLEQYCAKPAKSERDVSATSLQIIPMVPTIKQDVPRKHVTVKYSKYEAWQRKAAQRLRRGVPAILRARKFRRQAVKIKAQEQAMFHRPLITLPSKLPPVLPPTDNYVSHN

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Gallus gallus
Length
187 amino acids
Function
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for integrin which is required for IGF2 signaling.
Similarity
Belongs to the insulin family.
Mass
20.837 kDa
Sequence
MCAARQILLLLLAFLAYALDSAAAYGTAETLCGGELVDTLQFVCGDRGFYFSRPVGRNNRRINRGIVEECCFRSCDLALLETYCAKSVKSERDLSATSLAGLPALNKESFQKPSHAKYSKYNVWQKKSSQRLQREVPGILRARRYRWQAEGLQAAEEARAMHRPLISLPSQRPPAPRASPEATGPQE

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Sus scrofa
Length
181 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
20.313 kDa
Sequence
MGIPMRKPLLVLLVFLALASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVNRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFRYDTWKQSAQRLRRGLPALLRARRGRTLAKELEAVREAKRHRPLTARPTRDPAAHGGASPEASGHRK

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Equus caballus
Length
181 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
20.361 kDa
Sequence
MGIPVGKSLLMLFTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDDSPRYPVVKLFQYNAWKQSTQRLRRGLPALLRTRRGRMLVKELEAFREAQRHRPLIALPTEDPTPHGAAFVEVSSDLQ

Gene
Igf2
Protein
Insulin-like growth factor II
Organism
Rattus norvegicus
Length
180 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
20.086 kDa
Sequence
MGIPVGKSMLVLLISLAFALCCIAAYRPSETLCGGELVDTLQFVCSDRGFYFSRPSSRANRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTSQAVLPDDFPRYPVGKFFKFDTWRQSAGRLRRGLPALLRARRGRMLAKELEAFREAKRHRPLIVLPPKDPAHGGASSEMSSNHQ

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Homo sapiens
Length
180 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
20.14 kDa
Sequence
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK

Gene
Igf2
Protein
Insulin-like growth factor II
Organism
Mus musculus
Length
180 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
20.03 kDa
Sequence
MGIPVGKSMLVLLISLAFALCCIAAYGPGETLCGGELVDTLQFVCSDRGFYFSRPSSRANRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTSQAVLPDDFPRYPVGKFFQYDTWRQSAGRLRRGLPALLRARRGRMLAKELKEFREAKRHRPLIVLPPKDPAHGGASSEMSSNHQ

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Ovis aries
Length
179 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
19.616 kDa
Sequence
MGITAGKSMLALLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCAAPAKSERDVSASTTVLPDDFTAYPVGKFFQSDTWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSHRPLIALPTQDPATHGGASSEASSD

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Bos taurus
Length
179 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
19.682 kDa
Sequence
MGITAGKSVLVLLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPSSRINRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASTTVLPDDVTAYPVGKFFQYDIWKQSTQRLRRGLPAFLRARRGRTLAKELEALREAKSHRPLIALPTQDPATHGGASSKASSD

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Neovison vison
Length
129 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
14.437 kDa
Fragment
single
Sequence
MGVPMGKSLLAPLTFLALASCCFAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSAQRLRR

Gene
IGF2
Protein
Insulin-like growth factor II
Organism
Cavia porcellus
Length
128 amino acids
Function
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Similarity
Belongs to the insulin family.
Mass
14.42 kDa
Fragment
single
Sequence
MGISMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSASLAVLPDNFPRYPVGKFFQYDTWRQSTQRLRR