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id2-b

Gene
id2-b
Protein
DNA-binding protein inhibitor ID-2-B
Organism
Xenopus laevis
Length
135 amino acids
Function
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Inhibits the activity of both neurogenic (neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors. May play a role in the regulation of the circadian clock (By similarity).
Mass
14.99 kDa
Sequence
MKAFSPVRSVRKSSLTEHSLGIARSKAPVDEPMSLLYNMNDCYSKLKELVPSIPPNKKVSKMEILQHVIDYILDLQLTLDSHPTLVSLHHHHLSRVGGNTSRTPLTALNTDISILSLQAVELSSEFTDESKSLCP