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hypA

Gene
hypA
Protein
Protein HypA
Organism
Clostridium perfringens (strain 13 / Type A)
Length
973 amino acids
Mass
112.074 kDa
Sequence
MNFKENNIYSGFKLLNIENLNEIGGVGLRFEHEKTKAKLIKILSEDDNKCFAIGFRTPPENSTGVPHILEHSVLCGSRKFNTKEPFVELLKGSLNTFLNAMTYPDKTIYPVASRNEKDFMNLMDVYLDAVLYPNIYKHKEIFMQEGWHYYIENKEDELKYNGVVYNEMKGAYSSPDSILYRKIPQTIYPDTCYALSSGGDPDEIPNLTYEEFVEFHKKYYHPSNSYIFLYGNGDTEKELEFINEEYLKNFEYKEIDSEIKEQKSFESMKEESFTYGIAESEDLNHKSYYSLNFVIGDATDGEKGLAFDVLAYLLTRSTAAPLKKALIDAGIGKAVSGDFDNSTKQSAFTVLVKNAELNKEEEFKKVVMDTLKDLVENGIDKELIEASINRVEFELREGDYGSYPNGLIYYLKVMDSWLYDGDPYVHLEYEKNLEKIKSALTSNYFEDLIERYMINNTHSSLVSLHPEKGINEKKSAELKKKLEEIKNSFDEKTLNEIIDNCKKLKERQSTPDKKEDLESIPMLSLEDIDKEATKIPTEEKEIDGITTLHHDFHTNKIDYVNFFFNTNSVPEDLIPYVGLLCDILGKCGTENYDYSKLSNAINISTGGISFGAITFANLKKNNEFRPYLEISYKALSSKTNKAIELVDEIVNHTDLDDMDRIMQIIREKRARLEGAIFDSGHRIAMKKVLSYSTNRGAYDEKISGLDYYDFLVNIEKEDKKSTISDSLKKVRDLIFNKGNMLISYSGKEEEYENFKEKVKYLISKTNNNDFEKEEYNFELGKKNEGLLTQGNVQYVAKGGNYKTHGYKYSGALSLLESILGFDYLWNAVRVKGGAYGVFSNFRRDGGAYIVSYRDPNIKSTLEAYDNIPKYLNDFEADEREMTKYIIGTIRKYDQPISNGIKGDIAVSYYLSNFTYEDLQKEREEIINADVEKIKSFAPMIKDLMKEDYICVLGNEEKIKENKDLFNNIKSVIK

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
142 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.806 kDa
Sequence
MHELSVAQSVLETVLDVARKRGAERVLSVRLRIGEFTLLNPEQLRFCLEVLAEGTPVEGAKFEIEIERGYFKCAECGHRWRPEDESLKDPSLHTAFDLSELTELLDLKCPKCGSRAVKLDGGDACSIESVRLEVPGEQHAQG

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)
Length
141 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.761 kDa
Sequence
MHELSIAQSIVDVAGAEARRLGASSVRVVYLAIGRLSGIEPGALLFSYELVAADTPLAGSRLVIEDIPIAIHCAPCAAIHELPGVNRFRCPVCDTPSGDIRRGRELDITGLEIDDGASTDFDSIDHDTSALGASQAPEIPA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.609 kDa
Sequence
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLEGAELEIEVVPSKFVCKRCGHEWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVEIVQGTEFVIEGFEYQESNE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.753 kDa
Sequence
MHEWALADAIVRTALDYAQKENASKILAIKVVLGELQDVNAEVVEFAMKELLRGTIGEGAEIIFEEEEAVFRCRNCGHEWKLKEVKDKLDERIREDIHFIPEVVHAFISCPNCGSHDFEVVKGRGVYIAGIKIEKEEGE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.763 kDa
Sequence
MHEWALADAIVRTVLDYAQKEGASRVKAVKVVLGELQDVGEDIVKFAMEELFRGTIAEGAEIIFEEEEAVFKCRNCGHVWKLKEVKDKLDERIREDIHFIPEVVHAFLSCPKCGSHDFEVVKGRGVYISGIMIEKEGEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.847 kDa
Sequence
MHEWALADAIVRTVLEHAQKENASKVLAVKVVLGELQDVDAKIVEFAMNELFKGTIAEGAEIIFEEEEAVFKCRNCGYEWRLSEVREKLDERMREDIHFIPEVVHAFLSCPRCGSHDFEVVKGRGVYIAGIKIEKEGEQ

Gene
HYPA
Protein
Hydrophobin A
Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
Length
139 amino acids
Function
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Prevents recognition by the cellular immune defense system.
Similarity
Belongs to the fungal hydrophobin family.
Mass
14.373 kDa
Sequence
MKFSIAAAVLALASAVVAHPGAGYVSTPEKEANFQQNFQKFVTACGNGNQVSCCNTETKKVGAPLTAGGLIPILDNINLEDFSLLKGCSKVDVAAVIGVQDLLNSNCKTQVSCCKVGDTNQVGLVNANVDLKCAAQNII

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Thermococcus onnurineus (strain NA1)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.592 kDa
Sequence
MHEWALADGIVRTALDYAQREGAKKLLAIQVVLGELQDVNAEIVEFAMKELLKGTIGEGAEIEFIEEEAVFKCRDCGHEWKLKEVKGSFDERIKEDIHFIPEVVHAFLACPKCGSRDFEVVQGRGVYISGIKIEKEGEA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.738 kDa
Sequence
MHEWALADAIVRTVLDYAQREGAKRVKAVRVVLGELQDVAEDIVKFAMEQMFAGTIAEGAEIIFEEEEAVFKCRNCGHTWKLKEVKDRFDERIKEDIHFIPEVVHAFLACPKCGSHDFEVVQGRGVYVAGIMIEKEGEA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
139 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.689 kDa
Sequence
MHEWALADAIVRTVLDYAQREGASRVKAVRVVLGELQDVAEDIVKFAMEQLFAGTIAEGAEIEFVEEEAVFKCRNCNYEWKLKEVKDKFDERIKEDIHFIPEVVHAFLACPKCGSHDFEVVKGRGVYVAGIKIEKEGGS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Thermococcus sibiricus (strain MM 739 / DSM 12597)
Length
138 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.696 kDa
Sequence
MHEWALADGIVRTAIEFARQHGKEKVLAMRISLGELQDVNQEILEFAINEIKKGTIAEEAELEFIIEEAEFKCRNCGNEWKLKDVKESFNETIKEDIHFIPEVVHAFLACPNCGSRDFEVTKGRGVYLAAIKVEGDDE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
137 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
15.135 kDa
Sequence
MHELSIACEIFEQVKVTAEAHGATEVKHVTLQMGRLSHTNPEQLSFCFKTLAEGSIAENADLIVEMVPPTLECECGYTGTIDQERIRESNELTSELLAYIAAMDCPVCGKQAHIAGGRELIIKSIEIETENENESQR

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
133 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.728 kDa
Sequence
MHEYSIACEIFEQVIETAKVHGALEVRHVTLEMGRLSHTNPEQLSFCFKAIAEGSIAENAEFIVETIPPSLECECGYTGTVDETQIGKNDELQSELLEYIAALECPVCGKNARIIGGRELIVKSIEIETEVEQ

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
133 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.748 kDa
Sequence
MHELSIACEIFEQVMSTAKEHGATEVKHVTLQMGRLSHTNPEQLSFCFNVLADESIAKDADLIVEMIPPSLECECGYKGAVDEKKIRENCEFESELLAYAAVMECPVCGKPAQLTGGRELIIKSIEIETENQD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Synechococcus sp. (strain JA-2-3B'a(2-13))
Length
132 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.935 kDa
Sequence
MHETDMTRALIQTLRDWWQSQPGQPQIARVHLVVGQFTCVEPASLTFAYAAQTQGTFLQGSQLVIRETPLIAYCHPCGQEYKPEIGRRYACPNCGSPMEEIRSGRELKIDYIEIDYIECSTNFTPPAQPEVA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)
Length
131 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.629 kDa
Sequence
MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGAILAIQVPPIVLRCEECGQETNLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRELELVAAEVRRG

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Length
131 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.055 kDa
Sequence
MHEMSVALAVIDQVEQAAQQAGDVTAVRSVRLQVGELAGVVPDSLSFCFELACAGTVLEGADLVTEEVPGRARCAPCAREWSVGMPPRLSCPECGGARVDLLSGRELQIVSVHWEDGRTHAQTREPISEER

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Desulfatibacillum aliphaticivorans
Length
130 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.249 kDa
Sequence
MHEMGIALQIAEIAKSAIPKTPADLKVKAVNLRVGKLTAIVPDSLRFCFEIVAKDTPLAEAELNIEEIPIVAVCKECYTETIITDADFSCEKCKSGKLDIISGRELTVSSIEVADPEEMKQAQKKSKKEK

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
127 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.347 kDa
Sequence
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDAEIIINMIPIEVECEDCGFHGISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKIEREDENA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
126 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.141 kDa
Sequence
MHELSYATSVLNAILDAVKQQEELGRKVIKVNDINLEIGDLTLLSVDQLQFVFEVISEDTVCKGAELKAEIVKPKIFCMDCEFEGNLDTKDELEVACPKCESRNVKLKGGKEFNIVNATIEFDDEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Length
126 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.146 kDa
Sequence
MHELSYATSVLNAILDAIKQQETLGRKVIKVTDINLEIGDLTLLSVDQLQFVFEVISEDTVCNGAELKAEMVKPKIFCMDCEFEGNLDTKDELEVRCPKCESVNVKLKGGKEFNIVNATIEFDDEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
126 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.173 kDa
Sequence
MHELSYATSVLNAILEAVEQQEALGRKVIKVNDINLEIGELTLLSVDQLQFVFEVISEDTVCKGAELKAEMVKPKIFCMDCEFEGDLDTKDELEVICPKCESRNVKLKGGKEFNIVNATIEFDDEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
126 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.212 kDa
Sequence
MHELSYATSVLNAILDAVKQQEELGRKVIKVNDINLEIGDLTLISLDQLQFVFEVISEDTICKGAELKAEMVKPKIFCNDCEFEGNLDTKDELEVVCPKCESRNIKLKGGKEFNIVNATIEFDDEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)
Length
125 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.751 kDa
Sequence
MHELSMAQGIINAVIDTAESNNATEVTEVGIEIGRLAMINPEQLRFMLSVLVENTIVEDADIKIEEIPVEINCPECGFKGVAELDDKDHYAPIVECPKCGNKRISILNGKDCVVKNIVIEKPDDD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
124 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
14.058 kDa
Sequence
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLDCGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
124 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.728 kDa
Sequence
MHELSYATSILNSILEVLKEQESLGKKVTGVSEINLEIGDLTLISFEQLKFAFEVIAENTLCKNAVLNTEMIKPKISCLNCGFLGILEVTDELEAKCPKCGSMNVRIKGGKEFNIKNAIIEFDD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Length
123 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.706 kDa
Sequence
MHELSYATSIVNAIMEHITNMEQANKVKKVSKINLEIGELTFINFEQLKFAFEVASEGTLCKDAKLEAEFLKPHIACNNCGYRGELTANDEFEVKCPECGSLSLKISGGKEFNIKNAILESDE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Roseiflexus sp. (strain RS-1)
Length
123 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.217 kDa
Sequence
MHELSIAHSLVEIAEEAAAKAGVARVTVVHLRLGTLSGVVRDALLFGFDVASAGTRLEGARLEIEEVPLQVYCETCDTVVALPDVRYFRCPQCGAACRRIVTGQEIELAALEYEDDTPEATAS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
122 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.478 kDa
Sequence
MHELSMADAIVRTVIDAAEKNDAVEVLEVTVEIGQLTLLNPEQIEFMLDVLSEGTILEGARFNLEVVPVEIECECGYEGVVEADELDHFAPVIKCPACGGHEFHVRAGRECNVKNIKIEKKD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
120 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.68 kDa
Sequence
MHEASIALALIDVAGDVLREHGAARASALTVRVGQWSSVVPEALAAAFPACAEGTPLAGARLSIERVPGVGECPQHGPVELEVWRGLRCPLCGAPTPRLLQGDELELDQLELDQLELENL

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
119 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.858 kDa
Sequence
MHELSLAGGILQLLEDAARRERFARVTLLRLEAGKLCGVEVRALRFALEAIASGTCLEGACIEIEEPEGQAWCLQCNAAVALAERGAPCSGCGGYRLQPTAGTELRVMDMLVEDHWCPE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)
Length
119 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.219 kDa
Sequence
MHELSITEELLKTIVAKAEEAKARKISRINLVIGEYAGVVEDSVKMCFDILSQDTMAKGALLEFKRIPAEFRCRLCGHTFPSGQHALVCPKCQGWNAEVIAGNEFFIESIEVDDESQSS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Dehalococcoides mccartyi (strain ATCC BAA-2100 / JCM 16839 / KCTC 5957 / BAV1)
Length
119 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.151 kDa
Sequence
MHELSITEELLKTIVAKAEEAKARNVSRINLVIGEYAGVVEDSVKMCFEILSQDTIANGAILEFSRIPAKFRCRLCGHTFPSGQNLLVCPECQGWNAEVIAGNEFFIESIEVDDESQSS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Dehalococcoides mccartyi (strain CBDB1)
Length
119 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.137 kDa
Sequence
MHELSITEELLKTIVAKAEEAKARNVSRINLVIGEYAGVVEDSVKMCFEILSQDTIANGAVLEFSRIPAKFRCRLCGHTFPSGQNLLVCPECQGWNAEVIAGNEFFIESIEVDDESQSS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Length
119 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.075 kDa
Sequence
MHEYSIVTALLELCENHAKSNKAKKVTKVVVALGERSGVEPQLLESAFEVFKLDSVCAESELVIETKPMKFRCRSCGAEFLPKGIDFGSCEVCKAPNPELVGGKEMHLQSLEMEAEDEG

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.054 kDa
Sequence
MHEYSIVASLIQMCESHAKEHNAASIAKVCIAVGERSGVDSALVKSAFETFRLDSPLCQNTILEIQSQSVELECRDCGHYFQAQNLTYSTCPQCQSHNVIIAKGKELHLLSLELDIQS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Lawsonia intracellularis (strain PHE/MN1-00)
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.468 kDa
Sequence
MHEMSLVTGILSIIQEEMSKNGVNKLQRVKVCYGELTNIVPDSLQFAFKIFTEGTSLEGAILEIEKIPLMLRCSNCLSLFTPEDKQKIFFITCPSCKKEVAYNVETGREFYIQHLEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Salmonella typhi
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.485 kDa
Sequence
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.485 kDa
Sequence
MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSALSFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVADDGLQIRRIEIDETED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella oneidensis (strain MR-1)
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.216 kDa
Sequence
MHEYSIVSALIEQCEQYAKANQATKVTRVEIKLGVMSGVEPALLQTAFETFKLDGICREAKLCMTLQPLVIKCADCQQESVLDERSIVCPACNSYHTRVLDGEEMLLMQLEMEQAEDA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella sp. (strain MR-7)
Length
118 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.415 kDa
Sequence
MHEYSIVSALIEQCEQHAKANRANKITRVDIKLGVMSGVEPALLETAFETFKLDGICRDAELRMTLQPLVIACLDCHQESELTERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDEH

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Helicobacter pylori (strain J99 / ATCC 700824)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.202 kDa
Sequence
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE

Gene
hypA
Protein
Hydrogenase/urease maturation factor HypA
Organism
Helicobacter pylori (strain ATCC 700392 / 26695)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Is also required for urease maturation.
Similarity
Belongs to the HypA/HybF family.
Mass
13.202 kDa
Sequence
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.398 kDa
Sequence
MHELTLCQRAIEIIEQQAQQHGAKKVTAVWLEIGAFSCVETSSLDFCFGMVCRRTLAEGCQLHLHQQEAECWCYDCQQSVTLLTIQVRRCPQCQGDNLRIVADDGIQLKRMEIEQEI

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.672 kDa
Sequence
MHEMSIALSIVDAVVAKARQEGGVRISAIDLLIGKLAGIEPESLKFCFSAAARETLAAEALLNIEEPEGVGECGECGMSFPVNFYYAECPRCRSLRVKIVSGEEFLIQSMTIEEEGE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.811 kDa
Sequence
MHELSIAQSLLALIEDEMAKHGKEKLITVKVRHGRLSSVVPEALSMAFEVMTADSRLAGAALVMEETPVLLRCRDCSREFTPDPPTAAFAPCPGCGQELGHTVVSGRELYIEYLELE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chlorobium luteolum (strain DSM 273 / 2530)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.55 kDa
Sequence
MHEMSIAMSIVDAVDAKARAEGAVRISLIELKIGKLAGILPEALRFCFSAAATGSLAGQAQLVIDEPDGRGRCSDCGHEFSVDFYYARCPECGSLRIVIVSGEEFLIQSIIIDEEGE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella baltica (strain OS223)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.069 kDa
Sequence
MHEYSIVSALIEQCEQHALANHAAKITRVDIKLGVMSGVEPSLLQTAFDTFKLDGICNAAQLNIQIQPLVILCQDCQSESVLSERTIVCPACQSYRTRVLDGEDMLLMQLEMEQEED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella baltica (strain OS155 / ATCC BAA-1091)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.083 kDa
Sequence
MHEYSIVSALIEQCEQHALANHAAKITRVDIKLGVMSGVEPSLLQTAFDTFKLDGICKAAQLNIQIQPLVILCQDCQSESVLSERTIVCPACQSYRTRVLDGEDMLLMQLEMEQEED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella baltica (strain OS185)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.115 kDa
Sequence
MHEYSIVSALIEQCEQHALANHAAKITRVDIKLGVMSGVEPSLLQTAFDTFKLDSICKAAQLNIQIQPLVILCQDCQSESVLSERTVVCPTCQSYRTRVLDGEDMLLMQLEMEQDED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella baltica (strain OS195)
Length
117 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.097 kDa
Sequence
MHEYSIVSALIEQCEQHAQANHADKITRVDIKLGVMSGVEPSLLQTAFDTFKLDGICNAAQLNIQIQPLVILCQDCQTESVLSERTVVCPACQSFRTRVLDGEDMLLMQLEMEQNED

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Escherichia coli O157:H7
Length
116 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.168 kDa
Sequence
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
116 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.153 kDa
Sequence
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPLCHGDMLQIVADDGLQIRRIEIDQE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Escherichia coli (strain K12)
Length
116 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase (PubMed:12081959, PubMed:15995183). Mediates transfer of nickel, but not zinc, from the low-affinity metal-binding site in the GTPase domain of HypB to HypA (PubMed:23899293, PubMed:27951644). HypA is involved in maturation of hydrogenase 3. It may partially substitute for the function of HybF and vice versa (PubMed:12081959). May act as a scaffold for assembly of the nickel insertion proteins with the hydrogenase precursor protein after delivery of the iron center (PubMed:22016389).
Similarity
Belongs to the HypA/HybF family.
Mass
13.168 kDa
Sequence
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)
Length
116 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.258 kDa
Sequence
MHEMSIALSIVDAVDAQARVEGAGRISRVELVIGRLAGIEPESLRFCFPAAATGTLAEGAELDIEEIAAVAVCGACGFRFSVTFPVAECPECRSLRISVVSGEEFVIRSITIEEGD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shigella flexneri
Length
116 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.168 kDa
Sequence
MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.795 kDa
Sequence
MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Polaromonas naphthalenivorans (strain CJ2)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.178 kDa
Sequence
MHEASLAGGILKLVEDAARREAFQRVTVLRLEVGQLAGVELRALKFALEAIAPGTALDGARLEFEEPAGQAWCMACSQTVPLAARGMACTGCGSYQLQPTGGTELRVMDMLVADE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Desulfococcus oleovorans (strain DSM 6200 / Hxd3)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.25 kDa
Sequence
MHEMGIAMQIVEIAGGAIPSGIENPSVAKVNIRVGKLTAVVPTSLTFCFNIATQDTPLAGAELVIEEVPVVARCKQCGHEWIITGPDFSCETCRAGEVDILSGRELDIVSIELKE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.329 kDa
Sequence
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGSTLEIERAPLKVNCEACGLESEVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Nitratiruptor sp. (strain SB155-2)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.139 kDa
Sequence
MHEYSIVQSMLDLIEENAKKHNAMKVEKVVVKIGVMSGVEAHLLKIAFDTFKEGTLCSDAELEMIIQPIIAKCRACKKESRFEKNEIFYECKHCGDVDLEIVDGEDMILMQLDMN

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Aquifex aeolicus (strain VF5)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.783 kDa
Sequence
MHEFSIVQSLLTLIEDYARENNAKSVTKVVVSIGVLSGVEPHLLEMAFNTFKEGTVAEKAELIMEIEKLKIKCMDCGKESEKEELNMLCPGCGSLNTQIISGQDMFLKSLELEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Shewanella halifaxensis (strain HAW-EB4)
Length
115 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.896 kDa
Sequence
MHEYSIVTALIEECERHAFANNASKVSRVEIKLGILSGVEPELLRTAFETFKLEGICREANLVMNIQPLVLRCLDCGQSTEHSERSVICSHCQSGQTKVLDGEDMMLMQLELEQA

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Klebsiella pneumoniae (strain 342)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.914 kDa
Sequence
MHEITLSQRALEIIEQQAQQAGARRVTGVWLKVGAFSCVEASALTFCFELVCRGTLAEGCELHIAEQQAECWCERCQQYVHLVSQHVRRCPLCNNDQLQIVADDGLQIQRLELE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.924 kDa
Sequence
MHEITLSQRALEIIEQQAQQAGARRVTGVWLKVGAFSCVEASALTFCFELVCRGTLAEGCELHIAEQQAECWCDRCQQYVHLVSQHVRRCPHCNNDQLQIVADDGLQIQRLELE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Psychromonas ingrahamii (strain 37)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.662 kDa
Sequence
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGAELLIEDKLAQGVCQNCHLQVTTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.054 kDa
Sequence
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Cyanothece sp. (strain ATCC 51142)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.793 kDa
Sequence
MHELGITQNIVAIVLEQARGASVKRVTLEIGKLSAIMPEAIRFCFDICCQDTLLEGVTLEIIETEGKGKCRHCGHEIRLSQPFGQCDRCDSFELDIIQGQELQIKEMEVEELCV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Cyanothece sp. (strain PCC 8801)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.541 kDa
Sequence
MHELGITQNIIAIVAEQAKGIPVKRVTLEIGQLSAIMADSIRFCFDICCQGTVLEGATLEIIEILGRGKCRDCGQEIALFQPFGTCDRCGSIQLEIIQGQELKIKEMEIEEICV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.451 kDa
Sequence
MHEMSLMGGVFEAIEATLAHHHVKKVLLVKLKIGQLTNAEPDALQMAFAAFAQGTVCEGAELQIEMLPVKGRCRSCSEEFMVPGLIFACPVCQHLGIDITQGEELLLESLEVEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Desulfitobacterium hafniense (strain Y51)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.451 kDa
Sequence
MHEMSLMGGVFEAIEATLAHHHVKKVLLVKLKIGQLTNAEPDALQMAFAAFAQGTVCEGAELQIEMLPVKGRCRSCSEEFMVPGLIFACPVCQHLGIDITQGEELLLESLEVEE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Azoarcus sp. (strain BH72)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.064 kDa
Sequence
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGAAVDIEAVPGSGWCMQCATVVPIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.815 kDa
Sequence
MHELSVTQGLVDMLVEEAEKRKVKKVTKVTVVIGELTGIESESVKFYFDILTENTVAEGAELVFKIVRAQFKCTQCGNVFERSNFTFKCPVCGGQGVLIDKRGKEFYIESIEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
13.244 kDa
Sequence
MHELSIVESLIELCEENALNNKAYNVQEIYVKIGRLSGIEVDLFKRCFETFKENSNICKNAKLFIELAPLEILCLKCDQTSILEENVFKCPKCQSIEYKIIQGEDLHLMRLVMK

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.054 kDa
Sequence
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chloroflexus aggregans (strain MD-66 / DSM 9485)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.046 kDa
Sequence
MHELSIAHNIVNIASAAAAEAGTEEISAVYLRIGALAGVVADALRFSFAIAAEGTPLANAELIIEEVPVTVFCPTCNTEVTLPNPRLFRCPHCGRPCGQIIHGRELELVALETP

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Trichodesmium erythraeum (strain IMS101)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.521 kDa
Sequence
MHELGITQNIVAIVAENANNRLIKRVTLEIGELSAIMPNAIEFCFDVCTQGTVLEGATLEIIKIPGLGKCRQCATEIPLEQPFGICHVCNSVELDIIQGQELKIKEMEVEELSV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Syntrophus aciditrophicus (strain SB)
Length
114 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.6 kDa
Sequence
MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGATLEIDFLPIVISCLNCGEDTEVEYVEASCPECGSENVLLAGGTEELRLLELDVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Legionella pneumophila (strain Paris)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.689 kDa
Sequence
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Legionella pneumophila (strain Corby)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.689 kDa
Sequence
MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.686 kDa
Sequence
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Legionella pneumophila (strain Lens)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.686 kDa
Sequence
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.49 kDa
Sequence
MHELSLCEGILQILEEQSRTQGFIQVHRVCLEIGALASVEPEALRFHFDVVTQGTLAEGSHLEIVTVPAQAWCLPCGEKVSVGQYFDACPQCGSRQLQVIAGEELRIQQLEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Acidithiobacillus ferrooxidans (strain ATCC 53993)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.49 kDa
Sequence
MHELSLCEGILQILEEQSRTQGFIQVHRVCLEIGALASVEPEALRFHFDVVTQGTLAEGSHLEIVTVPAQAWCLPCGEKVSVGQYFDACPQCGSRQLQVIAGEELRIQQLEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / 130Z)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.933 kDa
Sequence
MHEMALTQNIIEIVEEQCRRNHVNKVTDIWLEIGPLSCVEPDAITFCFDVYSKDTVMENCKIHFIPVPALAYCWHCEKTVKIKTHHDACPECGGVHLQKQGGDELRIKEIAVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.205 kDa
Sequence
MHEMSLAMAAIDLAAEQATQRGFTKVTALWLEVGSFSCVDPDTIAFCFEAAAKGTAVEGAQLHFQHQAAEAWCYDCNKTVTLTERGQACPECGGYKLRVAQGDSLRITDIEVS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Paracoccus denitrificans (strain Pd 1222)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.548 kDa
Sequence
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGAVLEMIDLPGRAMCFDCAEQVELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.224 kDa
Sequence
MHEMSIALSVVDAITARAREEQAEKVTAIELVAGKLSGVEIESLKFCFSAAVRGTIMEDAELMVTVPLSEGLCEVCGERFAVDGYYTQCPSCGSYKVRIVSGKELSIRSITLE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhizobium leguminosarum bv. viciae
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.447 kDa
Sequence
MHEMSLMESVIEIVCETARQNGATRVKSVRLDVGVLSHVNPDALIFCYEAVRHGTVADSATLEINRIAGEGWCLDCGKTVALEERFGACPDCGRHRVQMTAGDELKIRDMEVI

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodobacter capsulatus
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.194 kDa
Sequence
MHEMSIVEGIRTAIEEAARANGFAKVTRVRLEIGRLAGVERAALDFAFDVVLRGSLAEGAAVQIIDLPGQAACFDCGKTVEIEHRLDICPECGGTRLLVQGGDEMRIKDLEVL

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.325 kDa
Sequence
MHEMSLAEGVLQLIEDAARKDHFAKVTTVWLEIGQLSGVEPEAMVFCFDAVTRDSVAQGARLEIMTLPGTAWCMACAETVPMAEVFGQCPQCGGYQLQVTGGTEMRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodopseudomonas palustris (strain BisA53)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.574 kDa
Sequence
MHEMSLCEGVIEIIEREAQQQNFAKVRTVWLEIGALSHVEPEAMRFCFSAVSHDTIAADARFEIVSVPGAAWCMACAKTVPLKQRYEPCPDCGGHQLQVTAGDELRVKELEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.533 kDa
Sequence
MHEMALCESMIEIIEREAREQQFSRVRAVWLEIGALGHVDPEAMRFCFSAVAHGGIAADARLEILEMPGAAWCMDCAKTVTIAQRDAPCPDCGGHHLQITAGEELRIRELEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodopseudomonas palustris (strain BisB5)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.381 kDa
Sequence
MHEMALCESMIEIIEREARDQHFARVRAVWVEIGALSHVEPEAMRFCFSAVAHGGIAADARFEIVSVSGAAWCMSCSKTVPLAQRSAPCPDCGGYQLQVTAGDELRVKELEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodopseudomonas palustris (strain TIE-1)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.533 kDa
Sequence
MHEMALCESMIEIIEREAREQQFSRVRAVWLEIGALGHVDPEAMRFCFSAVAHGGIAADARLEILEMPGAAWCMDCAKTVTIAQRDAPCPDCGGHHLQITAGEELRIRELEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.299 kDa
Sequence
MHEMSLCEGIRGIVEDQARRHGFATVKVLRLEIGRFAGVEKAALGFAFDVVMRGSAAEGARLEILDLPGRALCYDCGEEAAIEDRFDPCPLCGGGRLMPVGGDEMRIKDMEVQ

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.227 kDa
Sequence
MHEMSLCEGIRGIVGDQARRHGFATVKVLRLEIGRFAGVEKAALGFAFDVVMRGSAAEGARLEILDLPGRALCYDCGEEAAIEDRFDPCPLCGGGRLMPVGGDEMRIKDMEVQ

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodobacter sphaeroides
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.312 kDa
Sequence
MHEMSLCEGIRGIVEDQARRHGFATVKVLRLEIGRFAGVEKAALGFAFDVVMRGSAAEGARLEILELPGRALCYDCGEEAAIQDRFDPCPLCGGGRLMPVGGDEMRIKDMEVQ

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.975 kDa
Sequence
MHEMSIAMSVVEAVVDKAREEGGGKITGIDLVVGRLAGVEVESLKFCFGAAARGTLAEGAELVIEEPEGRGRCEACGAEFPVTSFYAKCSACGQFRVKIESGRELAVRSFTIE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Dechloromonas aromatica (strain RCB)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.117 kDa
Sequence
MHEMSLAEGVLQLVEDTARRESASRVKLVVLEIGRLSSVEPEAIKFCFEAVTHGSIAQGAALEIIAVPGAGWCMQCAETVPMTELYGACPTCGSHQVQPTGGTEMRVKEIEIE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.379 kDa
Sequence
MHELSIATDLINTALETAKQNNAREVISITVEIGELALINPEQLQFMYQVLTEENLLKGSELIIINVPAVAECQCGYKGPVPDKTTCACPNCGLTMRAVEGRDICLKTMEIEV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methylacidiphilum infernorum (isolate V4)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.241 kDa
Sequence
MHELSLCESLVSLLEEEMQKLGCGALKKVVLQVGPLALIEEGAMRFAFEVASKGTVVEGAELFIEWIAVRGYCLDCQKEALVYKIGESCPCCGGVMILSEEGKDLKVASIEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.518 kDa
Sequence
MHEISLIESVVALVEDERRKQDFSRVRMIRLRLGALGHAEPEALRFCFDAVTRGTIAEGARLDIDIVLGEGWCSSCSRTVPLEERFAACPICGNAPVQMTAGDELRVAEMEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.841 kDa
Sequence
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDAKLEIEEKPVRIRCRDCMAEKAVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.363 kDa
Sequence
MHEFGITQNIVAIVTEHAKGAKVQRVLLEIGKLSAIMPDAIRFCFDICTQGTVLEGATLEILEIPGLGRCRQCGGEIYLDKPFGICNCGSVQLDLITGEELKIKEIEIEELCV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.161 kDa
Sequence
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLEIREIPGLAKCRQCGAEIALEKPFGICGCGSVHLDVITGEELKIKEIEVEEVCV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Aeromonas salmonicida (strain A449)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.215 kDa
Sequence
MHEMSLAVAAIDLAAEQATQRGFNKVTALWLEVGSFSCVDPDTIAFCFEAAAKGTVVEGAQLHFQHQAAEAWCYDCDKTVTLTERGQACPECGGYKLRVAQGDSLRITDIEVS

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.742 kDa
Sequence
MHEMSLCEGILQILEEEARRQMFSRVRTVRLEVGELAGVELDAMYFGFDVVCRDTLADGARLEIVQRPGQAFCLGCGERVAVRRRFDACPDCGSYQLQVIGGDELRIKDLEVD

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.263 kDa
Sequence
MHELGITQNIVAIVNEYAHGAKVRRVLLEIGKLSAIMPDAIKFCFDICSQGTVLEGAVLEILEIPGLAKCRQCGAEIALEKPFGICNCGSVHLDLITGEELKIKEIEVEEVCV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.208 kDa
Sequence
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGAELVVLEEEGTAWCFDCNRTVPLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Azotobacter chroococcum mcd 1
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.593 kDa
Sequence
MHEMSIAEGIVQLLEEQAAAQRFERVKAVWLEIGPLAAVEVESLRFCFEAVTRGSLAEGARLEIVELPGRAWCLGCNASVAIRQRYDACPQCGSYRLQVTQGDELRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Azotobacter vinelandii
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.61 kDa
Sequence
MHEMSIAEGIVQLLEEQAVAQDFTRVRALWLEIGPLAAIEVESLRFCFEAVTRGSLAEGARLEIVELPGRAWCLGCNASVAIRRRYDACPQCGSHRLQVTQGDELRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.601 kDa
Sequence
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGAELELLEEPGAAWCFDCSETVPLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Bradyrhizobium sp. (strain ORS 278)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.366 kDa
Sequence
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGAALEIIEQKGSAWCLGCSRSVEISRRYDACSECGSHQLQVTGGEDMRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chlorobaculum parvum (strain NCIB 8327)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.154 kDa
Sequence
MHEMSIAMSVIDAVTEKARQEGCSKVTGIELVVGHLSGVEVESLKFCFSAACRDTPADGAELVIEECEAVGRCEACGETFPITSFYAKCPSCAQFRVQIESGQELSVRSITIE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Chlorobium phaeobacteroides (strain BS1)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.83 kDa
Sequence
MHEMSIAISIIDAVAAKAEAEHADTVTIVELEVGKVAGVEVESLKFCFSAAAKNTVAEGAELAVCEVEPVGECEACGQRFPVAFHVATCTSCGSFKTNIVSGRELLIKSITIE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.251 kDa
Sequence
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGAELVVLEEDGSAWCFDCCETVALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Rhodobacter sphaeroides (strain KD131 / KCTC 12085)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.297 kDa
Sequence
MHEMSLCEGIRGIVEDQARRHGFAAVKVLRLEIGRFAGVEKAALGFAFDVVMRGSAAEGARLEILDLPGRALCYDCGEEAVIEDRFDPCPLCGGGRLMPVGGDEMRIKDMEVQ

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)
Length
113 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.04 kDa
Sequence
MHEVAIMTETVAIANAAAERQNATKIVGLTMRIGAISGVVPEALSFAFEAVAGGTLAEQAQLIIETVPVTCYCAQCDRPFTPPDLFYECPLCSSLSQHILSGKEVELKSLEVI

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
Length
112 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.579 kDa
Sequence
MHEFSLCQSVISIAKKAAENNSKKVSKIVVKIGNLAGVDIESFEFWFPVAAKDSVLEQAKLEIIHEQAIAKCKACEHEFELTRLYEQCPNCGSFEKDILKGKDMLVESIVFN

Gene
hypA
Protein
Hydrophobin-1
Organism
Agaricus bisporus
Length
112 amino acids
Function
Forms hydrophobic rodlet layers.
Similarity
Belongs to the fungal hydrophobin family.
Mass
11.19 kDa
Sequence
MISRVLVAALVALPALVTATPAPGKPKASSQCDVGEIHCCDTQQTPDHTSAAASGLLGVPINLGAFLGFDCTPISVLGVGGNNCAAQPVCCTGNQFTALINALDCSPVNVNL

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Synechococcus elongatus (strain PCC 7942)
Length
112 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.219 kDa
Sequence
MHELSLATALVETALWQAVQAEAQQIVSLKLRLGTWAGVDAEALRFAFSLVQQDTIAASAQLVIESVPAQFRCQTCGQQTPPPLLAACSHCGSDRWQLQQGRELQLQSMEVV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
112 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.219 kDa
Sequence
MHELSLATALVETALWQAVQAEAQQIVSLKLRLGTWAGVDAEALRFAFSLVQQDTIAASAQLVIESVPAQFRCQTCGQQTPPPLLAACSHCGSDRWQLQQGRELQLQSMEVV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.674 kDa
Sequence
MHELSIARSVVDICTENAGGRRVCSVTIEIGALSGVATESIRFCFDACTRGTLLENALLLIEHVPASGRCRQCNSEFPVKACYDPCPACGGVGMDLITGEELRVKGLTVV

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.957 kDa
Sequence
MHEMSITQSVVEICEKSAGGRRVLAVTLEIGDLSGVVPDAIEFCFEACTRDTLLEGARLVIERVPGRGECTSCGKEFPVRGYFDPCPACGAYGMRVVSGEELRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.791 kDa
Sequence
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLAIDRVPGRGECGNCATVFPVRTYFDPCPACGAYGVRVVAGEELRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Geobacter sp. (strain M21)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.648 kDa
Sequence
MHEMSITQSVVEICEVHAAGRKVTEVVLLIGELSGVVPESVEFCFEACSKGTLLEGARLQLELVLGVGSCPACHGEFPISTLFEPCPGCGAFGLSVVAGEELRVKELELE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Geobacter uraniireducens (strain Rf4)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
11.957 kDa
Sequence
MHEMSITQSVVEICTQNAGGRRVTAVILEIGDLSGVVPDAIEFCFEACTRDTQLDGARLLIERVQALGRCRDCKAEFALSAYYDPCPACGGFGVDVLSGEELRVKELEVE

Gene
hypA
Protein
Hydrogenase maturation factor HypA
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
110 amino acids
Function
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Similarity
Belongs to the HypA/HybF family.
Mass
12.164 kDa
Sequence
MHEMSFAEAIIRNVLRFAEEKQAKTVTSVRVRVGELLLINPEQLQFCFSVASKGTIAEGAKLEISVERADIRCLLCGRELSKDEMLCECGGFAQVKGGKDFILESVVVEV