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hopAB3

Gene
hopAB3
Protein
Effector protein HopAB3
Organism
Pseudomonas syringae pv. tomato
Length
579 amino acids
Function
Effector protein involved in gene-for-gene resistance in tomato plants. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible plants, acts as a virulence factor by suppressing PCD and HR-based plant immunity. This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation (By similarity). Enhances the development of disease symptoms and bacterial growth.
Similarity
Belongs to the HopAB family.
Mass
61.819 kDa
Sequence
MAGINGAGPSGAYFVGHTDPEPASGGAHGSSSGASSSNSPRLPAPPDAPASQARDRREMLLRARPLSRQTREWVAQGMPPTAEAGVPIRPQESAEAAAPQARAEERHTPEADAAASHVRTEGGRTPQALAGTSPRHTGAVPHANRIVQQLVDAGADLAGINTMIDNAMRRHAIALPSRTVQSILIEHFPHLLAGELISGSELATAFRAALRREVRQQEASAPPRTAARSSVRTPERSTVPPTSTESSSGSNQRTLLGRFAGLMTPNQRRPSSASNASASQRPVDRSPPRVNQVPTGANRVVMRNHGNNEADAALQGLAQQGVDMEDLRAALERHILHRRPIPMDIAYALQGVGIAPSIDTGESLMENPLMNLSVALHRALGPRPARAQAPRPAVPVAPATVSRRPDSARATRLQVIPAREDYENNVAYGVRLLSLNPGAGVRETVAAFVNNRYERQAVVADIRAALNLSKQFNKLRTVSKADAASNKPGFKDLADHPDDATQCLFGEELSLTSSVQQVIGLAGKATDMSESYSREANKDLVFMDMKKLAQFLAGKPEHPMTRETLNAENIAKYAFRIVP

Gene
hopAB3
Protein
Effector protein hopAB3
Organism
Pseudomonas syringae pv. maculicola
Length
385 amino acids
Function
Effector protein involved in gene-for-gene resistance in tomato plants. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible plants, promotes virulence, in part, by enhancing the development of disease symptoms and bacterial growth.
Similarity
Belongs to the HopAB family.
Mass
41.628 kDa
Sequence
MVGISGRAGPSGSYNYSGHTDNPEPVSGRARDSNSEANSSNSPQVPPPLNAPASPMPAGRPRFLRSMALSSQTREWLEKGMPTEAEAGVPIRLQERAANTAPQARAEERHTQPADAAAPHARAERGRTLQAPASTSPLYTGAVPRANRIVQQLVEAGADLANIRTMFRNMLRGEEMILSRAEQNVFLQHFPDMLPCGIDRNSELAIALREALRRADSQQAARAPARTPPRSSVRTPERSPAPRTATESSSGSNQRSLLGRFAGLMTSNQRRPSSASNASTSQRPVDRNPPRINLMPTGANRVAMRNRGNNEADAALQALAQNGINMEDLRAALEAYIVWLRPIPLDIANALEGVGITPRFDNPEEAKVDNPLMNLSSALKRRLDA