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hokA

Gene
hokA
Protein
Protein HokA
Organism
Escherichia coli (strain K12)
Length
50 amino acids
Function
Toxic component of a type I toxin-antitoxin (TA) system (Probable). When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration (PubMed:10361310, PubMed:20105222). Its toxic effect is probably neutralized by antisense antitoxin RNA SokA (PubMed:10361310).
Similarity
Belongs to the Hok/Gef family.
Mass
5.998 kDa
Sequence
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE